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  • molecular
  • With the stable isotope-labeled amino acid, the deuteration of protein can be attained without damaging the NMR sensitivity of remaining hydrogen nucleus and, in addition, the rapid, accurate analysis of NMR spectrum of a high-molecular protein which is beyond the limitation in the prior art and the determination of the stereo-structure can be performed at the same time. (go.jp)
  • Guide to gels and transfer methods for high molecular weight proteins, featuring the Pierce Power Blotter. (thermofisher.com)
  • The molecular mechanisms driving physiological changes after long duration space flights revealed by quantitative analysis of human blood proteins. (nih.gov)
  • Molecular biologists are constantly challenged by the need to improve and optimise the existing expression systems, and also develop novel approaches to face the demands of producing the complex proteins of tomorrow. (springer.com)
  • Through his efforts as Associate Editor of the Journal of Biological Chemistry and Co-Editor of Molecular and Cellular Proteomics, he has guided protein and proteomics research to be published with the highest degree of confidence and has set standards to ensure results are properly analyzed and reported. (hupo.org)
  • synaptic
  • In this article, we report on the use of the Pierce Primary Neuron Isolation Kit method for generating high-yield, high-viability, high-quality neuronal cultures as manifested by their morphological characteristics, cell-specific protein expression, and the extent of synaptic scaling. (thermofisher.com)
  • 2018 . Identification of long-lived synaptic proteins by proteomic analysis of synaptosome protein turnover. (isotope.com)
  • gene
  • Our ready-to-use Mission TRC3 LentiORFs allow for stable integration, enrichment of cells, and long-term gene expression in difficult-to-transfect cell lines utilizing our best-in-class lentiviral manufacturing. (brighttalk.com)
  • This collection provides researchers with unique tools to gain insights into gene function by modulating gene and protein expression. (brighttalk.com)
  • signaling pathway
  • Rather, they involve a concerted effect from many proteins that may operate in a directed signaling pathway and/or may physically associate in a complex to achieve a specific enzymatic activity. (princeton.edu)
  • receptors
  • Colocalization studies and proteomic analyses suggest that GPR107 associates with clathrin and the retromer protein VPS35 and that GPR107 might be responsible for the return of receptors to the plasma membrane from endocytic compartments. (biologists.org)
  • integral
  • This article introduces the biology of Integral and peripheral membrane proteins (MPs) and their role in maintaining critical cellular functions. (thermofisher.com)
  • cells
  • Gpr107 -null fibroblast cells exhibit reduced transferrin internalization, decreased uptake of low-density lipoprotein (LDL) receptor-related protein-1 (LRP1) cargo and resistance to toxins. (biologists.org)
  • stability
  • For each candidate protein interaction, scores from the two workflows can be correlated to minimize nonspecific background and profile protein complex composition and relative stability. (princeton.edu)