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  • trypsin inhibitor
  • However, depending on their mode of preparation, soy isolates may contain trypsin inhibitor activity as high as 40% of that found in raw soybeans. (springer.com)
  • Trypsin inhibitor forms stronger polymer adduct than trypsin. (deepdyve.com)
  • We report the bindings of Received 18 August 2015 trypsin (Try) and trypsin inhibitor (Tryi) with polyamidoamine (PAMAM-G4) dendrimer at physiological Revised 20 September 2015 conditions, using thermodynamic analysis, UV-Visible and Fourier transform infrared (FTIR) spectro- Accepted 21 September 2015 scopic methods. (deepdyve.com)
  • Thermodynamic parameters DS, DH and DG showed protein-PAMAM bindings occur Available online 25 September 2015 via H-bonding and van der Waals contacts with trypsin inhibitor forming more stable conjugate than trypsin. (deepdyve.com)
  • viral
  • The DP16-1 cell line was derived from the spleen cells of a mouse infected with the polycythemia strain of Friend virus, and like other erythroleukemia cell lines transformed by this virus, it grows independently of erythropoietin, likely because of expression of the viral gp55 protein which binds to and activates the erythropoietin receptor. (semanticscholar.org)
  • This response to erythropoietin was not accompanied by down-regulation of viral gp55 protein. (semanticscholar.org)
  • In their efforts to inhibit HPV, Baleja and his team zeroed in on the viral protein E2, which controls viral activities including DNA replication and the activation of cancer-causing genes. (infectioncontroltoday.com)
  • MAPK
  • The purpose of this study was to investigate the usefulness of a p38 MAPK inhibitor for promoting proliferation of human corneal endothelial cells (HCECs). (arvojournals.org)
  • Activation of p38 MAPK signaling due to culture stress might suppress the proliferation of HCECs, whereas a p38 MAPK inhibitor can counteract this activation and enable efficient in vitro HCEC expansion. (arvojournals.org)
  • compound
  • Based on our results, we have identified specific, high affinity palmitoyl transferase inhibitors that will serve as a foundation for future compound design. (eurekaselect.com)
  • Herein, we show that the small molecule enoxacin, a fluoroquinolone used as an antibacterial compound, enhances the production of miRNAs with tumor suppressor functions by binding to the miRNA biosynthesis protein TAR RNA-binding protein 2 (TRBP). (sebbm.es)
  • CCND1
  • As a result, the expression of CCND1 and MCL1, proteins encoded by eIF4E-sensitive and cap-dependent transcripts, was refractory to AZD8055 in SW620:8055R cells. (biologists.org)
  • Forms a complex with cyclin type D- CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1 - CDK4 complex activation. (rcsb.org)
  • Sequence
  • Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed. (uniprot.org)
  • Enzymes
  • Heat treatment during processing serves to inactivate the inhibitors of trypsin and chymotrypsin, enzymes which play a key role in the digestion of protein in animals. (springer.com)
  • substrates
  • Autotrophic microalgae are photosynthetic, using solar energy, inorganic nutrients, and carbon dioxide (CO 2 ) to produce proteins, carbohydrates, lipids and other valuable organic compounds while heterotrophic microalgae can be fermented using simple organic substrates (for example, glucose, acetate, glycerol) as carbon and energy sources for cell growth without light. (mdpi.com)
  • tumor
  • In nutraceutical industries, Arthrospira ( Spirulina ) and Chlorella are the most important species in commercialization as health foods and nutrition supplements with various health benefits including enhancing immune system activity, anti-tumor effects, and animal growth promotion, due to their abundant proteins, vitamins, active polysaccharides, and other important compounds [ 5 , 6 ]. (mdpi.com)
  • Participants will be screened with a medical history, physical examination, blood tests, imaging studies, and potentially, tumor biopsy tests to determine whether a participant's NSCLC contains mutations in the KRAS protein. (clinicaltrials.gov)
  • ABSTRACT
  • article i nfo abstract Article history: Protein-polymer conjugates are widely used in therapeutic drug delivery. (deepdyve.com)
  • sensitivity
  • Consistent with our hypothesis that PIs induce the accumulation of misfolded ER-processed proteins, we found that the amount of immunoglobulin subunits retained within MM cells correlated with their sensitivity to PIs. (bloodjournal.org)
  • amplification
  • Defects at different steps in replication also increased Dup protein during an S-phase-like amplification cell cycle in the ovary, suggesting that Dup stabilization is sensitive to DNA replication and not an indirect consequence of a cell-cycle arrest. (biologists.org)
  • eukaryotic
  • Ito K et al (2008) Advanced method for high-throughput expression of mutated eukaryotic membrane proteins in Saccharomyces cerevisiae . (springer.com)
  • membrane
  • Using membrane techniques for the separation of TI from non-TI-protein, best results were obtained with 0.1 N. MgCl 2 where 79% of the TI was removed in the permeate. (springer.com)
  • conformation
  • In this article, small weight molecules of the imidazolidine series were screened from databases and optimized on silicon as the inhibitors of PTP1B based on the steric conformation and electronic configuration of thiazolidinedione (TZD) compounds. (mdpi.com)
  • Polymer interaction alters protein conformation. (deepdyve.com)
  • whereas
  • HCECs cultured with SB203580 exhibited hexagonal morphology and similar size and morphology, whereas control HCECs cultured without inhibitor exhibited monolayer morphology and varied in size and morphology. (arvojournals.org)
  • mRNA
  • XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin-mediated Rho-GDIβ mRNA stability. (semanticscholar.org)
  • interact
  • PIAS3 do, however, not only operate as SUMO-E3, since its coregulator effects are often independent of its RING-finger like domain but dependent on its capability to interact with sumoylated proteins via its conserved SIM (SUMO-interacting motif) or SAP (scaffold attachment factor-A/B/acinus/PIAS) domain (figure 2). (atlasgeneticsoncology.org)