Loading...
  • FASEB
  • This FASEB SRC will highlight current advances in our understanding of the pathways, mechanisms and enzymatic activities controlling RNA turnover in eukaryotic and prokaryotic cells and by viruses. (faseb.org)
  • This FASEB SRC brings together leaders in these fields, young up-and-coming faculty and the students and postdocs, who are actually doing the work to share the most current technical and conceptual advances, meet their colleagues from across the globe and establish new collaborations. (faseb.org)
  • This FASEB SRC is designed to highlight the major advances in science and integrate different topics, which are part of an extremely fast-moving and exciting field of research. (faseb.org)
  • This FASEB SRC focuses on the role of the immune system in the development and exacerbation of the many conditions that encompass metabolic syndrome. (faseb.org)
  • tyrosine
  • The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. (nih.gov)
  • SRC appears to be one of the primary kinases activated following engagement of receptors and plays a role in the activation of other protein tyrosine kinase (PTK) families. (nih.gov)
  • Receptor clustering or dimerization leads to recruitment of SRC to the receptor complexes where it phosphorylates the tyrosine residues within the receptor cytoplasmic domains. (nih.gov)
  • Western blot analysis of extracts from pervanadate-treated (1 mM for 5 minutes) NIH/3T3 cells that have been stably transfected with a constitutively active form of Src (in which the regulatory tyrosine 527 residue has been mutated to phenylalanine), A431 cells and HepG2 cells, using Non-phospho-Src (Tyr416) (7G9 ) Mouse mAb (top), v-Src antibody (middle) or Phospho-Src (Tyr416) Antibody #2101 (bottom). (cellsignal.com)
  • advances
  • This SRC will also highlight "epitranscriptomics" and should attract a whole range of researchers curious to learn the latest advances in this booming area of epigenetics. (faseb.org)
  • family
  • Due to functional redundancy between members of the SRC kinase family, identification of the specific role of each SRC kinase is very difficult. (nih.gov)
  • Western blot analysis of extracts NIH/3T3 cells, serum-starved or treated with human Platelet-Derived Growth Factor BB hPDGF-BB #8912 (100 ng/ml, 15 min), using Phospho-Src Family (Tyr416) (D49G4) Rabbit mAb (upper) or Src (36D10) Rabbit mAb #2109 (lower). (cellsignal.com)
  • focus
  • This SRC will focus on improving our understanding of the scientific (basic, socioeconomic, clinical, health policy) basis of disparities in cardiovascular health outcomes in the U.S. with a view to addressing the challenges posed at every level including complementary and integrative health. (faseb.org)
  • In recognition of the need to put the issue of health disparities front and center of health care delivery in the US, this SRC will focus on a multi-disciplinary approach to addressing health disparities and inequities in the United States. (faseb.org)
  • active
  • In addition to phosphorylating focal adhesion proteins, SRC is also active at the sites of cell-cell contact adherens junctions and phosphorylates substrates such as beta-catenin (CTNNB1), delta-catenin (CTNND1), and plakoglobin (JUP). (nih.gov)
  • members
  • Through the activities of the Council, SRC members make sure vocational rehabilitation programs are delivered with respect to individual dignity and informed consumer choice. (mass.gov)
  • At the end of the fiscal year, the MRC-SRC is still working with your administration on the gubernatorial appointments of our members. (mass.gov)
  • The lack of statutory appointments has negatively affected the ability of the SRC to have a full slate of members. (mass.gov)
  • together
  • This SRC series has historically brought together scientists involved with diverse systems and strategies, resulting in exciting and synergistic discussions. (faseb.org)