In addition of the categories of squamous dysplasia and carcinoma in situ , two additional lesions were added to the group of pre-invasive lesions: atypical adenomatous hyperplasia (AAH) and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). (ersjournals.com)
Gland type1
Integrated PET/CT of salivary gland type carcinoma of the lung in 12 patients. (radiopaedia.org)
Cancers4
Salivary gland-like carcinomas of the lung generally refers a class of rare cancers that arise from the uncontrolled cell division (mitosis) of mutated cancer stem cells in lung tissue. (wikipedia.org)
They take their name partly from the appearance of their abnormal cells, whose structure and features closely resemble those of cancers that form in the major salivary glands (parotid glands, submandibular glands and sublingual glands) of the head and neck. (wikipedia.org)
This class of primary lung cancers contains several histological variants, including mucoepidermoid carcinoma of the lung, adenoid cystic carcinoma of the lung, epithelial-myoepithelial carcinoma of the lung, and other (even more rare) variants. (wikipedia.org)
Non-small cell lung cancer (NSCLC) represents a heterogeneous group of lung cancers that do not have "small cells" on histology. (radiopaedia.org)
Lesion1
As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
Lung cancer is a large and exceptionally heterogeneous family of malignancies. (wikipedia.org)
However, since different forms of malignant tumors generally exhibit diverse genetic, biological, and clinical properties - including response to treatment - accurate classification of lung cancer cases are critical to assuring that patients with lung cancer receive optimum management. (wikipedia.org)
Some of the tests used to diagnose non-small cell lung cancer are also used to stage the disease. (solarproguide.com)
A lower body mass index, interstitial lung disease, prior pulmonary tuberculosis, larger clinical target volume, history of lung cancer surgery or radiation pneumonitis, and use of inhaled corticosteroids were independent risk factors for CPI development. (e-crt.org)
International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. (radiopaedia.org)
2 Although burn pits are only one of many possible sources of airborne hazards that may be encountered during deployment to Southwest Asia, they are the most well-recognized and -documented sources of smoke and fumes for a large number of service members. (nationalacademies.org)
Open burn pits were large, constructed holes that were used for waste disposal via combustion, with jet fuels often used as accelerants. (nationalacademies.org)
Genetic1
The effects of RT are mediated by energy deposition and the genetic damage it causes to the cells it passes through, resulting in reproductive cell death during cell division. (e-crt.org)
Tumour classification systems provide the foundation for tumour diagnosis and patient therapy and a critical basis for epidemiological and clinical studies. (ersjournals.com)
There has been substantial evolution of concepts in neuroendocrine lung tumour classification. (ersjournals.com)
An international system of tumour classification is important for consistency in patient treatments and to provide the basis of epidemiological and biological studies. (ersjournals.com)
If complete resection of tumor and lymph nodes is possible, such patients may benefit from surgery followed by postoperative chemotherapy. (solarproguide.com)
Features2
Carcinoma is a term for malignant neoplasms derived from cells of epithelial lineage, and/or that exhibit cytological or tissue architectural features characteristically found in epithelial cells. (wikipedia.org)
Large cell neuroendocrine carcinoma (LCNEC) is now recognized as a histologically high grade non small cell carcinoma showing histopathological features of neuroendocrine differentiation as well as immunohistochemical neuroendocrine markers. (ersjournals.com)
Patients3
Although at least 15 patients were to be enrolled in each of the tumor-specific expansions, up to 45 to 60 patients could be enrolled in each tumor-specific expansion. (solarproguide.com)
Assuming an equal number of patients having tumors with and without the biomarker, 45 or 60 patients provided approximately 85% power to differentiate 40% or 34.5% from 5% ORR, respectively. (solarproguide.com)
To maximize the power to detect the ORR difference between the biomarker groups, enrollment to a tumor-specific expansion could be adjusted to achieve approximately an equal number of patients having tumors with and without the biomarker. (solarproguide.com)
Invasive tumor1
A digital pathology platform was used for measuring total tumor size and invasive tumor size. (bvsalud.org)
NSCLC3
Because of the importance of stage in the therapeutic decision-making process, all patients with non-small cell lung cancer (NSCLC) must be staged adequately. (medscape.com)
The most common metabolic abnormality associated with NSCLC is hypercalcemia, which usually occurs with squamous cell carcinoma and results from secretion of parathyroid hormone-related peptide (PTH-rP) by the tumor. (medscape.com)
Giant cell carcinomas of the lung are a rare type of non-small cell lung carcinomas ( NSCLC ) classified under sarcomatoid carcinomas of the lungs . (radiopaedia.org)
Malignant7
Carcinoma is a term for malignant neoplasms derived from cells of epithelial lineage, and/or that exhibit cytological or tissue architectural features characteristically found in epithelial cells. (wikipedia.org)
However, since different forms of malignant tumors generally exhibit diverse genetic, biological, and clinical properties - including response to treatment - accurate classification of lung cancer cases are critical to assuring that patients with lung cancer receive optimum management. (wikipedia.org)
WHO, 2001) Malignant C45929 Acidophil Stem Cell Pituitary Gland Adenoma Acidophil Stem Cell Adenoma An infrequent pituitary gland adenoma composed of cells showing immunoreactivity for prolactin and less often growth hormone. (nih.gov)
Acinic Cell Carcinoma A malignant glandular epithelial neoplasm consisting of secretory cells forming acinar patterns. (nih.gov)
Malignant C40367 Acinic Cell Breast Carcinoma A breast adenocarcinoma characterized by the presence of serous (acinic cell) differentiation. (nih.gov)
Malignant Pituitary Gland Corticotropinoma A rare, hormonally functioning or non-functioning pituitary gland adenocarcinoma that produces corticotropin. (nih.gov)
Giant cell carcinomas are composed mostly of malignant giant cells, without differentiated carcinomatous elements 4 . (radiopaedia.org)
Benign6
Code Preferred Term Synonyms Definition Neoplastic Status C7419 Acanthoma A benign skin neoplasm composed of epithelial cells. (nih.gov)
Clear cell tumors of the lung are rare benign pulmonary neoplasms that contain an abundant amount of glycogen. (radiopaedia.org)
2. Liebow AA, Castleman B. Benign clear cell ("sugar") tumors of the lung. (radiopaedia.org)
A rare cause of hemoptysis: benign sugar (clear) cell tumor of the lung. (radiopaedia.org)
Benign clear (sugar) cell tumor of the lung with CD1a expression. (radiopaedia.org)
6. Jordá aragón C, Froufe sánchez A, Padilla alarcón J. [Benign clear cell tumor of the lung]. (radiopaedia.org)
Classification1
INTRODUCTION: Since the eight edition of the Union for International Cancer Control and American Joint Committee on Cancer TNM classification system, the primary tumor pT stage is determined on the basis of presence and size of the invasive components. (bvsalud.org)
Peripheral1
Giant cell carcinomas often present with peripheral neutrophilia and fever related to the production of granulocyte colony-stimulating factor (G-CSF) 3 . (radiopaedia.org)
Therapy1
Epidemiological features of lung giant cell carcinoma and therapy for patients with EGFR mutations based on case reports and the surveillance, epidemiology, and end results (SEER) database. (radiopaedia.org)
Type4
Salivary gland-type tumors of the trachea. (co.us)
EZH2 (≥80% staining) had a sensitivity of 81% for thymic carcinoma and a specificity of 100% for thymic carcinoma versus type A thymoma and MNTLS but had poor specificity (46%) for thymic carcinoma versus B3 thymoma. (bvsalud.org)
Overall, absent EZH2 staining may be useful for excluding thymic carcinoma, diffuse EZH2 staining may help to exclude type A thymoma and MNTLS, and ≥10% POU2F3 staining has excellent specificity for thymic carcinoma versus thymoma. (bvsalud.org)
Location2
This can be achieved by sputum cytologic studies, bronchoscopy, or computed tomography (CT)-guided transthoracic needle biopsy of the mass, depending on the location of the tumor (see the image below). (medscape.com)
RESULTS: The mean coefficient of variation for measuring total tumor size and tumor invasive size was 6.9% (range: 1.7%-22.3%) and 54% (range: 14.7%-155%), respectively, with substantial variations in interpretation of the size and location of invasion among pathologists. (bvsalud.org)
Primary1
This class of primary lung cancers contains several histological variants, including mucoepidermoid carcinoma of the lung, adenoid cystic carcinoma of the lung, epithelial-myoepithelial carcinoma of the lung, and other (even more rare) variants. (wikipedia.org)
Analysis1
METHODS: A Delphi approach was used with two rounds of blinded anonymized analysis of resected nonmucinous lung adenocarcinoma cases with presumed invasive and noninvasive components, followed by one round of reviewer de-anonymized and unblinded review of cases with known outcomes. (bvsalud.org)
Rare1
Salivary gland-like carcinomas of the lung generally refers a class of rare cancers that arise from the uncontrolled cell division (mitosis) of mutated cancer stem cells in lung tissue. (wikipedia.org)
Mass1
Clear cell "sugar" tumor of the lung: a well-enhanced mass with an early washout pattern on dynamic contrast-enhanced computed tomography. (radiopaedia.org)