• A series of 75 lung carcinomas (47 squamouscell carcinomas, 24 adenocarcinomas, 3 small cell carcinomas, and 1 large cell carcinoma) was analyzed for the extent ofapoptosis by using the 3' end-labeling method of DNA in tissue sections. (dokumen.tips)
  • Large cell carcinoma: Cancer in which the cells are large and look abnormal when viewed under a microscope. (doereport.com)
  • ients with recurrent unresectable or metastatic cervix carcinoma with squamous cell, adenocarcinoma or adenosquamous histology immediately after at the very least on prior platinum-based chemotherapy for metastatic/recurrent illness.Coquan et al. (trpv1inhibitor.com)
  • BMC Cancer(2021) 21:Page 5 ofTable 1 Study eligibility criteriaInclusion criteria - Female 18 years of age or older, with histologically confirmed recurrent unresectable or metastatic cervix carcinoma with squamous cell, adenocarcinoma or adenosquamous histology. (trpv1inhibitor.com)
  • We report a case of simultaneous Squamous cell carcinoma(SCC) of cervix and fallopian tube (invasive). (amrita.edu)
  • Women with primary untreated invasive squamous-cell carcinoma, adenosquamous carcinoma, or adenocarcinoma of the cervix of stage IIB, III, or IVA, without involvement of the para-aortic lymph nodes, were enrolled. (nih.gov)
  • Cervical cancer is cancer that starts in the cells of the cervix. (navigatingcare.com)
  • Before cancer appears in the cervix, the cells of the cervix go through changes known as dysplasia, in which abnormal cells begin to appear in the cervical tissue. (navigatingcare.com)
  • Over time, if not destroyed or removed, the abnormal cells may become cancer cells and start to grow and spread more deeply into the cervix and to surrounding areas. (navigatingcare.com)
  • Very rarely, cancer develops in other cells in the cervix. (navigatingcare.com)
  • The most common ones are adenocarcinomas and squamous cell carcinomas. (lccs.com.sg)
  • Macroscopically, ulcerative carcinomas are poorly-differentiated adenocarcinomas, which invade deeply into the stomach wall. (poznayka.org)
  • Microscopically, fungating or polypoid carcinomas are well-differentiated adenocarcinomas, commonly papillary type. (poznayka.org)
  • Cervical adenocarcinomas develop in the glandular cells of the endocervix. (navigatingcare.com)
  • In terms of tumor histologic types, the patients included 26 adenocarcinomas, 4 bronchioloalveolar carcinomas, 10 squamous cell carcinomas and 5 adenosquamous carcinomas. (cyp17-signal.com)
  • Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR), including gefitinib and erlotinib, have become the standard first-line therapy for patients with advanced non-small cell lung cancers (NSCLCs) harboring activating EGFR mutations ( 4 , 5 ). (spandidos-publications.com)
  • Lung cancers are histologically classified as Small Cell Lung Cancer (SCLC) or Non-Small Cell Lung Cancer (NSCLC). (frontiersin.org)
  • Esophageal adenosquamous carcinoma (ASC) is a rare tumor with characteristics of adenocarcinoma (AC) and squamous cell carcinoma (SCC), the two most common esophageal cancers. (nih.gov)
  • The predominant histological types are squamous cell cancers. (scirp.org)
  • Cervical cancers are named after the type of cell where the cancer started. (navigatingcare.com)
  • Most cervical cancers (up to 90%) are squamous cell carcinomas. (navigatingcare.com)
  • These cancers develop from cells in the ectocervix. (navigatingcare.com)
  • Fungating carcinoma of the colon Edges and margins of an intestinal tumor Adenocarcinoma is a malignant epithelial tumor, originating from superficial glandular epithelial cells lining the colon and rectum. (wikipedia.org)
  • It originates from the glandular cells that line the inner surface of the gallbladder. (healthtrip.com)
  • This is a hybrid form, comprising both glandular and squamous cells. (healthtrip.com)
  • Microscopically, early gastric carcinoma is a typical glandular adenocarcinoma, usually well-differentiated. (poznayka.org)
  • Esophageal Primary Intrahepatic Adenosquamous Carcinoma (IASC) is defined by the coexistence of both squamous and glandular elements in the same lesion histologically. (oncologyradiotherapy.com)
  • The endocervix is covered with column-shaped glandular cells that make mucus. (navigatingcare.com)
  • Adenocarcinoma: Cancer that begins in cells that have glandular (secretory) properties. (doereport.com)
  • These cells also have glandular (secretory) properties. (doereport.com)
  • Preoperative imaging for high-risk cutaneous squamous cell carcinoma (HRcSCC) of the head and neck lacks robust diagnosis-specific data regarding utility and lacks established guidelines regarding indications. (ahns.info)
  • This study explored the expression of Ln5 and the role of its relationships with PTEN, phospho-EGFR (p-EGFR) and phospho-Akt (p-Akt) in the prognosis of patients with non-small cell lung cancer (NSCLC). (spandidos-publications.com)
  • This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. (rush.edu)
  • Lung cancer is divided into two major groups: non small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). (scielo.br)
  • 2004) Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer. (scielo.br)
  • 2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. (scielo.br)
  • Metz H, Busch SE, Hanke ML, Kargl J, Kim KH and Houghton M (2014) Insulin receptor substrate-1 regulates immune cell content in lung adenocarcinoma. (scielo.br)
  • Small cell lung cancer (SCLC) is characterized by poor prognosis and challenging diagnosis. (frontiersin.org)
  • Screening in high-risk smokers results in a reduction in lung cancer mortality, however, screening efforts are primarily focused on non-small cell lung cancer (NSCLC). (frontiersin.org)
  • It represents a large group of epithelial lung malignancies which can be divided into two clinical groups: SMALL CELL LUNG CANCER and NON-SMALL-CELL LUNG CARCINOMA . (lookformedical.com)
  • Lung cancer originates from cells of the lung. (lccs.com.sg)
  • these are your small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). (lccs.com.sg)
  • The latter, non-small cell lung cancer (NSCLC) is much more common than its counterpart. (lccs.com.sg)
  • Treatment of small cell and non-small cell lung cancer are different. (lccs.com.sg)
  • Lung cancer is caused by the genetic mutation to cells, causing them to grow abnormally. (lccs.com.sg)
  • They are typically differentiated by the type of cells in the lung from which the cancer develops. (lccs.com.sg)
  • Although anaplastic lymphoma kinase ( ALK ) fusion genes are generally identified in lung adenocarcinoma patients, they are relatively rare in patients with squamous cell carcinoma (SqCC). (biomedcentral.com)
  • Numerous oncogenic driver mutations have been identified in patients with non-small cell lung cancer. (biomedcentral.com)
  • Research has reported that two genes in particular (human epidermal growth factor receptor [ EGFR ] and anaplastic lymphoma kinase [ ALK ]) are associated with improvements in therapeutic efficiency in non-small cell lung cancer patients receiving targeted therapies. (biomedcentral.com)
  • Compound epidermal growth factor receptor ( EGFR ) mutations are less responsive to tyrosine kinase inhibitors (TKIs) than single EGFR mutations in non-small cell lung cancer (NSCLC). (biomedcentral.com)
  • The relationship between operative invasiveness and the prognosis in non-small cell lung cancer (NSCLC) patients who have undergone surgery has been controversial. (researchsquare.com)
  • Video-assisted thoracic surgery (VATS) for patients with non-small cell lung cancer (NSCLC) has been widely adopted and the advantages of the VATS approach have been reported [1-7]. (researchsquare.com)
  • 2. Categorisation of lung tumours by cytomorphology and with immunohistochemistry on cell block wherever available. (patholjournal.com)
  • IHC confirmed the diagnosis of adenocarcinoma in 30 cases, squamous cell carcinoma in 10 cases, neuroendocrine carcinoma in 11 cases and adenosquamous carcinoma in 2 cases, and 1 case of plasmacytoma lung. (patholjournal.com)
  • Genetic analysis by fluorescence in situ hybridization of lung cancer cells obtained by bronchial brushing Uemura Y, Kobayashi M, Muneishi H, Urata T, Hakoda E, Tanaka Y et al, l?drd Dept. of Internal Medicine, Kochi Medical School, Kochi 783. (dokumen.tips)
  • The most frequent signal spots in class V cells (Case 1-7) ranged from 3 to 5, followed by 6 to 8, regardless of histopathological findings of lung cancer. (dokumen.tips)
  • Enhanced apoptosis predicts shortened survival in non-small cell lung carcinoma Tormanen U, Eerola A-K, Ramio P, Vahakangas K, Soini Y, Sormunen R et al. (dokumen.tips)
  • This study was undertake0 to determine the extent of apoptosis in lung carcinoma and to evaluate it as a prognostic marker. (dokumen.tips)
  • Non-small cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung. (doereport.com)
  • There are two types of lung cancer: non-small cell lung cancer and small cell lung cancer. (doereport.com)
  • Refer to the PDQ summary on Small Cell Lung Cancer Treatment for more information. (doereport.com)
  • The five types of non-small cell lung cancer have different kinds of cancer cells. (doereport.com)
  • For most patients with non-small cell lung cancer, current treatments do not cure the cancer. (doereport.com)
  • Clinical trials are taking place in most parts of the country for patients with all stages of non-small cell lung cancer. (doereport.com)
  • After lung cancer has been diagnosed, tests are done to find out if cancer cells have spread within the lungs or to other parts of the body. (doereport.com)
  • Between February 2009 and July 2013, 402 patients with clinical stage I non-small cell lung cancer (NSCLC) underwent "non-grasping en bloc MLND" conducted by one surgical team. (medscape.com)
  • Though the majority of the primary tumors are hepatocellular carcinoma (HCC), some rare diseases also could not be ignored by the reason of their characteristics. (biomedcentral.com)
  • These are rare tumors that arise from the hormone-producing cells in the gallbladder. (healthtrip.com)
  • Gastric carcinoma comprises more than 90% of all gastric malignant tumors. (poznayka.org)
  • Among malignant neoplasms of the penis, squamous cell carcinoma (SCC) is the most common. (medscape.com)
  • The concept does not refer to neoplasms located in tissue composed of squamous elements. (lookformedical.com)
  • In situ carcinomas may progress to invasive lesions. (medscape.com)
  • In situ carcinomas include Bowen disease , erythroplasia of Queyrat , and bowenoid papulosis . (medscape.com)
  • carcinoma in situ in the stomach (a state of severe cellular atypia or dysplasia, without invasion across the basement membrane of the glands). (poznayka.org)
  • Immunohistochemistry is helpful in subtyping non- small cell carcinoma, NOS and poorly differentiated carcinoma into adeno, squamous and neuroendocrine carcinomas. (patholjournal.com)
  • Meanwhile, 40 hepatocellular carcinoma (HCC) patients and 26 metastatic hepatic SCC or ASC patients who were hospitalized in the same period were also reviewed to make a comparison. (biomedcentral.com)
  • ASC is a rare tumor among esophageal carcinomas with a greater burden of metastatic disease than AC or SCC and worse OS than AC. (nih.gov)
  • If untreated, these conditions may evolve to invasive carcinomas. (medscape.com)
  • Invasive adenocarcinoma commonly displays: Varying degrees of gland formation with tall columnar cells Frequently desmoplasia Dirty necrosis, consisting of extensive central necrosis with granular eosinophilic karyorrhectic cell detritus. (wikipedia.org)
  • A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane. (lookformedical.com)
  • An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST. (lookformedical.com)
  • SCC of the prostate is a rare malignant epithelial neoplasm arising in the prostate, with squamous differentiation of the neoplastic cells. (medscape.com)
  • [ 12 , 13 ] The time course for the appearance of squamous differentiation in the carcinoma varies from 3 months to many years (up to 9 years) after therapy. (medscape.com)
  • Rarely, they have foci of squamous differentiation (morules). (wikipedia.org)
  • A pathology report contains a description of the microscopical characteristics of the tumor tissue, including both tumor cells and how the tumor invades into healthy tissues and finally if the tumor appears to be completely removed. (wikipedia.org)
  • Tumor cells describe irregular tubular structures, harboring pluristratification, multiple lumens, reduced stroma ("back to back" aspect). (wikipedia.org)
  • Sometimes, tumor cells are discohesive and secrete mucus, which invades the interstitium producing large pools of mucus. (wikipedia.org)
  • Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes. (rush.edu)
  • Nevertheless, nonresponders had been resistant to all or any ALK inhibitors, regardless of the existence of ALK rearrangement in FISH-positive circulating tumor cells and circulating free of charge DNA and lack of the ALK inhibitor level of resistance mutation. (exposed-skin-care.net)
  • A cell line derived from cultured tumor cells. (lookformedical.com)
  • carcinoma contains abundant pools of mucin in which are seen a small number of tumor cells, sometimes having signet-ring appearance. (poznayka.org)
  • Upon immunohistochemical (IHC) analysis, the tumor cells exhibited strong positive staining for p40 and cytokeratin 5/6, but were negative for thyroid transcription factor-1 (Fig. 2b-d ). (biomedcentral.com)
  • Drugs used in chemotherapy, such as cisplatin and tirapazamine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. (stanford.edu)
  • Radiation therapy uses high-energy x-rays to kill tumor cells. (stanford.edu)
  • Internal radiation uses radioactive material placed directly into or near a tumor to kill tumor cells. (stanford.edu)
  • Cisplatin and tirapazamine may make tumor cells more sensitive to radiation therapy. (stanford.edu)
  • The apoptotic indexes (percentages of apoptotic cells and bodies among tumor cells) were slightly higher in adeoocarciooma than in squamous cell carcinoma. (dokumen.tips)
  • PET scan (positron emission tomography scan): A procedure to find malignant tumor cells in the body. (doereport.com)
  • Malignant tumor cells show up brighter in the picture because they are more active and take up more glucose than normal cells. (doereport.com)
  • Colorectal carcinoma with desmoplastic reaction (*) Dirty necrosis Determining the specific histopathologic subtype of colorectal adenocardinoma is not as important as its staging (see #Staging section below), and about half cases do not have any specific subtype. (wikipedia.org)
  • Primary Intrahepatic Adenosquamous Carcinoma (iASC) is a very rare subtype of Cholangiocarcinoma (CCA), with a worse prognosis than adenocarcinoma. (oncologyradiotherapy.com)
  • Precancer - Colorectal villous adenoma A lesion at least "high grade intramucosal neoplasia" (high grade dysplasia) has: Severe cytologic atypia Cribriform architecture, consisting of juxtaposed gland lumens without stroma in between, with loss of cell polarity. (wikipedia.org)
  • D) Medullary carcinoma: Neoplastic cells with syncytial appearance (thick yellow arrow) and eosinophilic cytoplasm associated with abundant peritumoral and intratumoral lymphocytes. (wikipedia.org)
  • The cadherin-catenin complex also influences migration and modifies cell growth and the survival of neoplastic cells [8]. (cyp17-signal.com)
  • C) Signet ring carcinoma: More than 50% of signet cells with infiltrative growth pattern (thin red arrow) or floating in large pools of mucin (thick red arrow). (wikipedia.org)
  • B) Mucinous carcinoma: Presence of extracellular mucin (>50%) associated with ribbons or tubular structures of neoplastic epithelium. (wikipedia.org)
  • Adenocarcinoma - this type develops from the mucus-producing gland cells of the endocervix. (nhengswonderland.net)
  • We determined that miR-375-3p can discriminate between SCLC and NSCLC patients, and between SCLC and Squamous Cell Carcinoma patients. (frontiersin.org)
  • This study sought to investigate the efficacy and safety of a three-drug combination antiemetic regimen of olanzapine combined with aprepitant and palonosetron for the prevention of chemoradiotherapy-induced nausea and vomiting in locally advanced head and neck squamous cell carcinoma. (centerwatch.com)
  • Primary hepatic ASC was defined as a liver tumor containing definite components of both adenocarcinoma and squamous cell carcinoma, and sometimes it was considered as a variant of cholangiocarcinoma [ 9 ]. (biomedcentral.com)
  • The cause of penile squamous cell carcinoma (SCC) is unclear, although human papillomavirus (HPV) appears to play a major role in many cases. (medscape.com)
  • Human Papillomavirus (HPV) Infection Human papillomavirus (HPV) infects epithelial cells. (msdmanuals.com)
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
  • A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. (lookformedical.com)
  • In tumor tissue, thenumber of apoptotic bodies was roughly 2-fold greater than the number of apoptotic cells, whereas in oonneoplastic control tissues, the ratio was 1: 1. (dokumen.tips)
  • Genital warts, which are a form of benign tumor of epithelial cells, are also caused by various strains of HPV. (wikipedia.org)
  • A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. (lookformedical.com)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (lookformedical.com)
  • These vesicles are constitutively secreted by all cell types and EVs released from cancer cells can functionally alter recipient cells by reprogramming them to become active contributors to tumor growth, metastasis, and immunosuppression ( 10 ). (frontiersin.org)
  • We reviewed the clinical features and outcomes of three primary hepatic squamous cell carcinoma (SCC) patients and six primary hepatic adenosquamous carcinoma (ASC) patients from January 1998 to December 2011 in Eastern Hepatobiliary Surgery Hospital in China. (biomedcentral.com)
  • Various autoantibodies (including antinuclear, thyroid antimicrosomal, antigastric parietal cell, anti-adrenal cortex, antismooth muscle, and antimitochondrial antibodies) have been detected in patients with lichen sclerosus. (medscape.com)
  • We profiled deregulated circulating cell-free miRNAs in the plasma of SCLC patients. (frontiersin.org)
  • The disease in patients from whom class I cells were obtained was found to be malignant by other diagnostic procedures performed afterward. (dokumen.tips)
  • Primary carcinoma of the fallopian tube is a rare neoplasm, accounting for only 0.3-1.1% of all gynecological malignancies [1]. (amrita.edu)
  • Also, our mutants induced proliferation, glucose uptake, inhibited the migration of 293T cells and affected the responsiveness of the cells to cisplatin and radiation. (scielo.br)
  • Macroscopically, the lesions of early gastric carcinoma may have 3 patterns-superficial, polypoid and ulcer-associated. (poznayka.org)
  • Apoptosis was correlated with the rate of cell proliferation, the immunohistochemically detectable p53 and bcl-2, the extent of tumor necrosis, and the survival data. (dokumen.tips)
  • There are still several controversies and ambiguities in the aspects of primary hepatic squamous cell carcinoma and primary hepatic adenosquamous carcinoma. (biomedcentral.com)
  • Both primary hepatic squamous cell carcinoma (SCC) and adenosquamous carcinoma (ASC) are very rare. (biomedcentral.com)
  • Adeno-carcinoma is the predominant type and is included in the criteria established by Finn and Javert for diagnosis of primary carcinoma of fallopian tube [2]. (amrita.edu)
  • A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
  • Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. (lookformedical.com)
  • Laminin 5 (Ln5) is an extracellular matrix protein that plays an important role in cell migration and tumor invasion. (spandidos-publications.com)
  • These single-stranded non-coding RNAs drive the post-transcriptional repression of gene expression ( 9 ) and can be released to the extracellular environment either as circulating cell-free molecules or encapsulated within extracellular vesicles (EVs). (frontiersin.org)