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  • cholesterol
  • Inhibitors of squalene epoxidase have found application mainly as antifungal drugs: butenafine naftifine terbinafine Since squalene epoxidase is on the biosynthetic pathway leading to cholesterol, inhibitors of this enzyme may also find application in treatment of hypercholesterolemia. (wikipedia.org)
  • adjuvant squalene
  • [2009 oct] Belgian doctors call for sack of government virologist in row over swine flu adjuvant advice The Belgian association of doctors has called for the government's interministerial commissioner for the flu, the virologist Marc Van Ranst, to be fired after he said on Thursday that the Pandemrix swine flu jab with the adjuvant squalene was safe for pregnant women. (whale.to)
  • adjuvants
  • Injection of not only the classical complete Freund's adjuvant but also mineral oil without mycobacteria and pure adjuvants such as pristane and squalene, induce severe arthritis in many rat strains. (whale.to)
  • Arthritogenic adjuvants like pristane, avridine, squalene and mineral oil are not immunogenic since they do not contain major histocompatibility complex (MHC) binding peptides. (whale.to)
  • Squalene is one of those adjuvants. (thefullwiki.org)
  • In addition to the viruses and other additives, many vaccines also contain immune adjuvants like aluminum and squalene. (educate-yourself.org)
  • Three reference antigens: Plasmodium falciparum apical membrane antigen 1 (AMA1), hepatitis B virus surface antigen (HBsAg), and Mycobacterium tuberculosis antigen 85A (Ag85A), were selected as model antigens and were each formulated with three adjuvants: aluminium oxyhydroxide, squalene-in-water emulsion, and a liposome formulation mixed with the purified saponin fraction QS21. (readbyqxmd.com)
  • intermediates
  • A Japanese group has investigated the role of aromatic amino acids for stabilizing cationic intermediates in the enzyme sites of squalene synthases, which bring about one of the most beautiful and classic reaction cascades in biology. (fieldofscience.com)
  • synthase
  • Squalene synthase is crucial for balancing the incorporation of farnesyl diphosphate (FPP) into sterol and nonsterol isoprene synthesis. (uniprot.org)
  • In particular, a high level of squalene production (400 ± 45 mg/L) was obtained in shake flasks with the Y2805 strain overexpressing genes encoding a bacterial farnesyl diphosphate synthase (ispA) and a truncated form of hydroxyl-3-methylglutaryl-CoA reductase (tHMG1). (readbyqxmd.com)
  • 2016
  • The squalene market is estimated to reach USD 211.76 Million by 2021 and is projected to register a CAGR of 10.2% between 2016 and 2021. (sbwire.com)
  • Seattle, WA -- ( SBWIRE ) -- 11/02/2016 -- The report "Squalene Market Type (Animal-Sourced and Vegetable-Sourced) and by End-Use Industry (Cosmetics, Pharmaceuticals & Food) - Global Forecasts to 2021", The global squalene market is projected to reach USD 211.7 Million by 2021 and is projected to register a CAGR of 10.2% between 2016 and 2021. (sbwire.com)
  • 2002
  • O'Sullivan L, Woods JA, O'Brien NM (2002) Squalene but not n-3 fatty acids protect against hydrogen peroxide-induced sister chromatid exchanges in Chinese hamster V79 cells. (springer.com)
  • molecular
  • Squalene is physically refined, molecular distilled from Shark Liver Oil, not chemically processed, and encapsulated in a laboratory that is GMP licensed by the New Zealand Food Safety Authority. (lovelyhealth.com)
  • antioxidant
  • Squalene (SQ) possesses a wide range of pharmacological activities (antioxidant, drug carrier, detoxifier, hydrating, emollient) that can be of benefit to the ocular surface. (mdpi.com)
  • Plant active Olive Squalene has been touted the 'antioxidant of the future', with its incredible biocompatibility to the skin. (botani.com.au)
  • Olive Squalene is a proven antioxidant and free-radical scavenger. (botani.com.au)
  • Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignansa. (nih.gov)
  • The aim of this study was to evaluate the phenolic antioxidant and squalene content in a range of olive and seed oils. (nih.gov)
  • Gulf War Synd
  • When Professor R.F. Garry went before the House of Representatives to advocate against the use of 2-3 micrograms of Squalene because it had a relationship with Gulf War Syndrome. (abovetopsecret.com)
  • triterpene
  • We mainly focus on squalene hopene cyclases, class II triterpene synthases that use a proton-initiated cationic polycyclization cascade to form carbopolycyclic products. (diva-portal.org)
  • mainly
  • Squalene, which is stored mainly in the shark's liver , is lighter than water with a specific gravity of 0.855. (thefullwiki.org)
  • This is mainly due to its renewable nature, steady availability of raw material, and the skepticism and regulations regarding animal-sourced squalene. (sbwire.com)
  • shark
  • Squalene is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil, though plant sources (primarily vegetable oils) are used as well, including amaranth seed, rice bran, wheat germ, and olives. (healthyaction.com.au)
  • Squalene is a 99.5% pure extract of Shark Liver Oil. (lovelyhealth.com)
  • Buy Southern Deep's premium quality SHARK SQUALENE at Lowest Prices, direct from New Zealand! (lovelyhealth.com)
  • We who live in New Zealand are fortunate in regard to Shark Squalene because in our clean Southern Oceans our deep sea sharks are plentiful and are caught as a by product of fishing foe other species. (lovelyhealth.com)
  • This is what has prompted me to offer my own brand of finest Shark Liver Oil and Squalene called Southern Deep at very competitive prices. (lovelyhealth.com)
  • For more info about the history, research, composition and health benefits of deep sea Squalene and Shark Liver Oil click here. (lovelyhealth.com)
  • Because of the Latin name for Shark Liver Oil: Squalene exogene oleum, Shark Liver Oil can be offered to you as 'Squalene' but in that case it is not real pure Squalene! (lovelyhealth.com)
  • Many commercially available Squalene oils and supplements are derived from shark liver. (botani.com.au)
  • Capsules
  • Recently it has become a trend for sharks to be hunted to process their livers for the purpose of making squalene health capsules. (thefullwiki.org)
  • Beware of copy-cat products that give you a low price but don't tell you the origin and/or the mg content of the capsules Are you aware that 'Asian brands' of Squalene could originate all the way from Europe? (lovelyhealth.com)
  • molecules
  • A mere 10 ppb concentration of squalene translates into approximately 184 trillion molecules of squalene and an equal number of potentially destructive immune responses. (wordnik.com)
  • oils
  • Squalene is a low density compound often stored in the bodies of cartilaginous fish such as sharks , which lack a swim bladder and must therefore reduce their body density with fats and oils. (thefullwiki.org)
  • Issho Genki Squalene is extracted from the liver oils of the deep-sea dogfish - a very prolific fish that can be found in just about every region in the world. (experts123.com)