Spreading depression. Medical search. Frequent questions

Cortical spreading depression (CSD) or spreading depolarization (SD) is a wave of electrophysiological hyperactivity followed by a wave of inhibition. (wikipedia.org)
Neuroscientists use the term cortical spreading depression to represent at least one of the following cortical processes:[citation needed] The spreading of a self-propagating wave of cellular depolarization in the cerebral cortex. (wikipedia.org)
Increased extracellular potassium ion concentration and excitatory glutamate contribute to the initiation and propagation of cortical spreading depression, which is the underlying cause of migraine aura. (wikipedia.org)
Valproate and riboflavin were shown to have no effect on the triggering of cortical spreading depression though they are effective in migraine without aura. (wikipedia.org)
Taken together, these results are compatible with a causal role of cortical spreading depression in migraine with aura, but not in migraine without aura. (wikipedia.org)
Different characteristics of cortical spreading depression in the sleep and wake states. (iasp-pain.org)
The objective of this study is to characterize the effects of the sleep-wake cycle on neurovascular and behavioral characteristics of cortical spreading depression (CSD). (iasp-pain.org)
Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model. (synergy-munich.de)
Cortical spreading depression (CSD), a wave of depolarization followed by depression of cortical activity, is a pathophysiological process implicated in migraine with aura and various other brain pathologies, such as ischemic stroke and traumatic brain injury. (synergy-munich.de)
The low-frequency brainwave linked to migraines and epilepsy is known as cortical spreading depression (CSD) and is currently best studied by placing electrodes directly on the surface of the brain. (sciencedaily.com)
Cortical spreading depression has never before been accurately measured using EEGs, according to UBC electrical and computer engineering professor Guy Dumont, Bastany's supervisor and study co-author. (sciencedaily.com)
The new method opens up uses for EEGs in studying cortical spreading depression in a non-invasive manner and without a significant increase in diagnostic costs compared to standard EEG," said Dumont. (sciencedaily.com)
VALENCIA, Spain-A poster presentation at the 17th Congress of the International Headache Society in Valencia, Spain, reported that vagus nerve stimulation (VNS) inhibits cortical spreading depression (CSD), which is known to be the cause of migraine aura and a trigger for headache. (drugdiscoverynews.com)

The scintillating scotoma of migraine in humans may be related to the neurophysiologic phenomenon termed the spreading depression of Leão. (wikipedia.org)
The most important modifiable risk factors for chronic migraine include overuse of acute migraine medication, ineffective acute treatment, obesity, depression and stressful life events. (nature.com)
We then examine the potential role that extracellular H+ released by glia might play in regulating synaptic transmission within the vertebrate retina, and then expand the focus to discuss potential roles in spreading depression, migraine, epilepsy, and alterations in brain rhythms, and suggest that alterations in extracellular H+ may be a unifying feature linking these disparate phenomena. (uic.edu)

The Great Depression was the most significant macroeconomic event of the past century, but don't expect to find an accurate portrayal of its causes in your college history classroom . (joeyhudson.com)
In a new study I co-authored with Jeremy Horpedahl and Marcus Witcher , we examined nine widely used US history textbooks and evaluated their accounts of the Great Depression. (joeyhudson.com)
To illustrate the range of economic explanations for the Great Depression, we summarized ten of the most commonly used college-level economics textbooks below. (joeyhudson.com)
Monetary explanations of the Great Depression were seldom mentioned at all. (joeyhudson.com)
all nine history textbooks attributed the Great Depression to a class of explanations known as "underconsumption" theory. (joeyhudson.com)
For the past 80 years, few if any economists have seriously entertained "underconsumption" as a viable explanation of the Great Depression. (joeyhudson.com)
Eight out of nine US history textbooks attributed the Great Depression to rising income inequality. (joeyhudson.com)
Tellingly, none of the history textbooks offered a coherent causal mechanism by which inequality supposedly caused or triggered the Great Depression. (joeyhudson.com)
is badly out of sync with the scholarly literature on the Great Depression. (joeyhudson.com)
The resulting treatment of the Great Depression i n US history textbooks does little to educate students about the actual causes of the Great Depression. (joeyhudson.com)
The crash of the New York Stock Exchange on October 29, 1929, signaled the start of the Great Depression, the worst economic crisis in U.S. history. (encyclopedia.com)
Are You Prepared For The Coming Economic Collapse And The Next Great Depression? (theeconomiccollapseblog.com)
the result was the Great Depression. (typepad.com)

Spreading depolarization describes a phenomenon characterized by the appearance of depolarization waves of the neurons and neuroglia that propagates across the cortex at a velocity of 1.5-9.5 mm/min. (wikipedia.org)
Spreading depolarization within brainstem tissues regulating functions crucial for life has been implicated in sudden unexpected death in epilepsy, by way of ion channel mutations such as those seen in Dravet syndrome, a particularly severe form of childhood epilepsy that appears to carry an unusually high risk of SUDEP (sudden unexpected death in epilepsy). (wikipedia.org)
INTRODUCTION Peri-infarct distributing depolarization waves (PIDs) akin to distributing Olanzapine (LY170053) depression frequently happen in ischemic or hemorrhagic stroke and after head trauma in both animal and human being brains (Dohmen et al. (ecologicalsgardens.com)
CSD is a local disturbance in the occipital cortex region of the brain, which is caused by a slowly propagating wave of depolarization-suppression of electrical activity-spreading across the cortex. (drugdiscoverynews.com)

Peri-infarct depolarizations (PIDs) are seemingly spontaneous spreading depression-like waves that negatively impact cells outcome in both experimental Olanzapine (LY170053) and human being stroke. (ecologicalsgardens.com)

Similar to the Iranian government, which released 73,000 inmates , the Indonesian government plans to release at least 30,000 detainees to prevent the spread of coronavirus in the country's overcrowded jails. (medicalxpress.com)
Alabama's colleges and universities are planning in case coronavirus spreads into the state. (wsfa.com)
MONTGOMERY, Ala. (WSFA) - Alabama's colleges and universities are taking notice of the rapidly spreading coronavirus. (wsfa.com)

In animal models, iprazochrome was shown not to decrease the spreading depression velocity, which is a feature of other antimigraine agents and is thought to be one of the essential causes of classical migraines. (wikipedia.org)

There is two-way communication between the brain and the immune system, so we had to determine whether activation of the body's immune system sent a signal to the brain to affect mood and behavior or whether the depression activated the immune system," study leader Dr. Jesse Stewart of Indiana University - Purdue University Indianapolis said in a statement. (indianapolisrecorder.com)
It's believed to be caused by a wave of electrical activity that spreads across the cortex of the brain. (healthline.com)

Depression itself is a disabling illness leading to considerable illness and early death. (cmaj.ca)
In all of these interviews, a higher than expected proportion of patients reported depression immediately after their illness. (cdc.gov)
In addition to the objective measurement using the CES-D scale, we also asked patients if they were experiencing depression since their illness and if they had a previous history of depression, with yes/no responses elicited. (cdc.gov)
Wash hands frequently and cover your mouth and nose when coughing or sneezing to avoid spreading illness. (cdc.gov)

As I mentioned earlier, over the years of talking to and working with lifters struggling with various forms of anxiety and depression (as well as my own experiences as a competitor), I've found that many lifters find that max effort work has a direct and sizable impact on their mental health symptoms. (elitefts.com)
But mothers with clear symptoms of depression or anxiety weren't getting any treatment. (thetyee.ca)
Intervention For two years, a depression care manager worked with primary care physicians in intervention practices to provide algorithm based care for depression, offering psychotherapy, increasing antidepressant dose if indicated, and monitoring symptoms, adverse effects of drugs, and adherence to treatment. (bmj.com)
21 - 31 Most reported an increased risk of diabetes associated with a history of depression or depressive symptoms, but often only in selected subpopulations. (cmaj.ca)
We can learn and spread the word about early warning signs and symptoms of childhood cancer. (cdc.gov)

A great ring of EU states stretching from Eastern Europe down across Mare Nostrum to the Celtic fringe are either in a 1930s depression already or soon will be. (telegraph.co.uk)

Women who were pregnant during the pandemic scored significantly higher on the questionnaires measuring stress, depression, and anxiety. (umn.edu)
Every two to four years, subjects completed questionnaires that measured depression and loneliness, gave their medical history and underwent a physical examination. (livescience.com)

Just because you struggle with anxiety or depression doesn't mean you need to make these adjustments. (elitefts.com)
A peer team often includes students who have struggled with anxiety or depression themselves, but who have since overcome their problems. (nea.org)

Results In baseline clinical interviews, 396 people were classified as having major depression, 203 had clinically significant minor depression, and 627 did not meet criteria for depression. (bmj.com)
Patients with major depression in usual care were more likely to die than were those without depression (hazard ratio 1.90, 95% confidence interval 1.57 to 2.31). (bmj.com)
In contrast, patients with major depression in intervention practices were at no greater risk than were people without depression (hazard ratio 1.09, 0.83 to 1.44). (bmj.com)
Conclusions Older adults with major depression in practices provided with additional resources to intensively manage depression had a mortality risk lower than that observed in usual care and similar to older adults without depression. (bmj.com)
22-60, the patient may be experiencing major depression. (cdc.gov)

The link to cardiovascular disease demonstrates that there may be physical as well as mental health reasons to treat depression. (indianapolisrecorder.com)
It could be that having a stronger social network is an effective way to treat depression. (socialworktoday.com)

Objective To investigate whether an intervention to improve treatment of depression in older adults in primary care modified the increased risk of death associated with depression. (bmj.com)
The objective of our study was to evaluate whether people with diabetes have a greater incidence of depression than those without diabetes. (cmaj.ca)
We describe the subjective and objective evaluations of depression in these patients. (cdc.gov)
This scale is a commonly used method for objective measurement of clinical depression. (cdc.gov)

1 2 The biological, social, psychological, and behavioral mechanisms that mediate the effect of depression on mortality have only recently begun to be elucidated. (bmj.com)

Considering the main routes of movement for older adults amid the spread of COVID-19, 10 local community centers, 3 senior welfare centers, senior clubs, and 3 branches of the Korean Senior Association (Wonmi, Ojeong, Sosa Braches) were asked for the cooperation of the survey. (who.int)

They looked at more than 2,000 adolescents in a network of US high school students to see how their mood influenced each other by modeling the spread of mood using similar methods to those used to track the spread of infectious diseases. (socialworktoday.com)
These results suggest that promotion of any friendship between adolescents can reduce depression since having depressed friends doesn't put them at risk, but having healthy friends is both protective and curative. (socialworktoday.com)
For example, if many adolescents drink a lot of alcohol and their friends drink a lot too, it may be that alcoholic drinks cause depression among the young people rather than who they're friends with. (socialworktoday.com)

We recently conducted a large, population-based, nested case- control study 21 that suggested an association between a history of depression and the onset of type 2 diabetes, but this increased risk was limited to people no older than 50 years. (cmaj.ca)
We therefore conducted a population-based retrospective cohort study to evaluate the incidence of new-onset depression among people with diabetes, compared with those who do not have diabetes. (cmaj.ca)

In the recent TV special "Explorer: Bill Nye's Global Meltdown," which premiered Sunday, November 1, on the National Geographic Channel, Nye guides viewers through the "five stages of climate grief"-denial, anger, bargaining, depression, and acceptance-as a means of grappling with his own feelings about climate change. (nationalgeographic.com)

U.S. researchers found depression leads to elevated levels of an inflammatory protein in the body. (indianapolisrecorder.com)

The team found that while depression doesn't "spread," having enough friends with healthy mood can halve the probability of developing, or double the probability of recovering from, depression over a six-to-12-month period. (socialworktoday.com)

In the case of infectious disease, you can spread your sickness to others by coming to work sick. (cdc.gov)

But then the anger and the depression about my father's death set in. (lingq.com)

Loneliness spreads They found loneliness is catchy with three degrees of separation. (livescience.com)
Levels of C-reactive protein - another inflammatory protein - were also measured but were not found to be related to depression. (indianapolisrecorder.com)
BOSTON , Sept. 2, 2020 /PRNewswire/ -- After analyzing millions of member check-in data across 2,873 gyms, sports clubs and boutique fitness centers over the course of three months, The International Health, Racquet & Sportsclub Association (IHRSA) and MXM, a technology and knowledge transfer company specializing in member tracking within the fitness industry, conclusively found that fitness facilities are safe and are not contributing to the spread of COVID-19. (prnewswire.com)
No significant effect on mortality was found for minor depression. (bmj.com)
Using a large, population-based administrative cohort, we found little evidence that type 2 diabetes increases the risk of depression once comorbid diseases and the burden of diabetes complications were accounted for. (cmaj.ca)
We further measured this outcome and found that 31% of patients reported new-onset depression and 75% of these had Center for Epidemiologic Studies Depression scores indicative of mild-to-severe depression. (cdc.gov)

In "River of Time: My Descent Into Depression and How I Emerged With Hope," Judd shares her harrowing personal experience with the severe depression that almost killed her. (christianactivities.com)

Such knowledge could influence clinical practice by suggesting who would most effectively be screened for depression and by evaluating ways to prevent people with diabetes from becoming depressed, in order to decrease both the patients' risk of complications and the cost of the ensuing treatments. (cmaj.ca)

Prospective studies have consistently shown an association between depression and increased mortality in older adults. (bmj.com)
It is necessary to improve the public's consideration and awareness of older adults drivers, such as the spread of silver mark awareness. (who.int)

I wrote it with the sincere hope of offering encouragement to the 40 million Americans who suffer from depression and anxiety every minute of every day and night," Judd said. (christianactivities.com)
Many survivors suffer from anxiety and depression. (cdc.gov)

Participants identified smoking and environmental exposures as causes of cancer, but many believed operating on tumors caused cancer to spread. (cdc.gov)

Dawn Nunziato, a George Washington University Law School professor, spoke at a virtual event Wednesday about social media's influence on the spread of fake news. (dailyfreepress.com)

People from all faiths took part in the iftar that aimed to spread the message of love. (medindia.net)
People who smoke tobacco and cannabis have an increased risk of depression and anxiety than those who use either substance alone or not at all. (medindia.net)
Loneliness, like a bad cold, can spread among groups of people, new research finds. (livescience.com)
While a runny nose might spread through handshakes, people likely catch the loneliness bug through negative interactions. (livescience.com)
We also know that social support is important for recovery from depression: for example, having people to talk to. (socialworktoday.com)
The incidence of new-onset depression was similar in both groups (6.5 v. 6.6 per 1000 person-years among people with and without diabetes, respectively). (cmaj.ca)
Several investigations 5 - 8 have documented that people with diabetes experience depression from 1.3 to 3 times as often as those without the disorder. (cmaj.ca)
Little information is currently available on the obverse of that temporal chain: the incidence of depression among people who have diabetes. (cmaj.ca)
The spread of HIV and AIDS has had a major social and economic impact on many countries, leaving large numbers of people in need of care and support. (who.int)

More work needs to be done but it may be that we could significantly reduce the burden of depression through inexpensive, low-risk social interventions. (socialworktoday.com)

Vitiligo begins as small patches, which slowly spread, often involving ultimately large areas of the body's surface. (jewishencyclopedia.com)

8 Investigators seeking to understand the biological mechanisms linking depression and medical conditions have drawn attention to cardiovascular, immunologic, inflammatory, metabolic, and neuroendocrine pathways. (bmj.com)

The spreading of a wave of ischemia passing through an area of cortex. (wikipedia.org)
The spreading of a wave of vasoconstriction following vasodilation and prolonged sustained vasoconstriction of contiguous cortical arterioles. (wikipedia.org)

It will not be enough to prevent the spread of respiratory infections in detention facilities when the main factor that puts inmates at high risk of infection is overcrowding. (medicalxpress.com)

Physical fitness has long-term mental health benefits as well, including reducing the risk of stress and depression. (prnewswire.com)
3 4 A strong association exists between depression in late life and factors that increase mortality risk, such as poor adherence to medical treatment and self care for diabetes and cardiovascular disease, 5 health behaviors such as smoking and lack of physical activity, 6 cognitive impairment, 7 and disability. (bmj.com)
Although diabetes mellitus has a strong association with the presence of depression, it is unclear whether diabetes itself increases the risk of developing depression. (cmaj.ca)
Several prospective studies have evaluated the risk of diabetes in those with previous depression. (cmaj.ca)

Other chronic conditions such as arthritis (HR 1.18) and stroke (HR 1.73) were associated with the onset of depression. (cmaj.ca)

Although there was no difference in the time to initiate treatment before and after the policy change (1.7 hours), nurses reported that they were able to order contact precautions earlier than they previously would have to prevent the spread of CDI to other patients. (umn.edu)
However, there is currently no peer-reviewed data supporting the use of a small molecule modulator of HCN channels in depression treatment. (frontiersin.org)
Org 34167, a benzisoxazole derivative, has been patented for the treatment of depression and progressed to Phase I trials. (frontiersin.org)
Therefore, there remains an unmet need for efficacious, on-target therapeutic strategies for patients with treatment-resistant depression. (frontiersin.org)

A year after the outbreak of WNV in New York City, 38% of patients subjectively reported depression ( 4 ). (cdc.gov)
Another 1-year follow-up in Colorado noted that 23% of patients reported anxiety and depression ( 5 ). (cdc.gov)

It's not clear whether a third dose is effective in preventing the spread of mumps. (medicalxpress.com)
It's become abundantly clear that the safety measures gyms, sports clubs and boutique fitness centers have in place are not only incredibly effective at keeping their membership safe, but also curbing any potential spread of COVID-19 during a time when we all need access to exercise facilities to stay healthy. (prnewswire.com)

Anxiety, stress, depression are mental health conditions that a person can't just 'get over' or 'move on' from. (wgntv.com)

1 - 4 Another comorbidity associated with diabetes that is increasingly recognized is depression. (cmaj.ca)
9 , 10 When associated with diabetes, depression increases the risks of work loss, 11 functional disability, 11 , 12 and micro- 13 and macrovascular complications, 14 and adds to health care costs. (cmaj.ca)
13 , 15 Diabetes with comorbid depression is also linked with poorer adherence to medications and self-care activities such as self-monitoring of blood glucose levels and adhering to a proper diet and exercise program. (cmaj.ca)

Loneliness has been linked with various mental and physical illnesses , including depression. (livescience.com)
and physical functioning (Barthel Index) and depression. (cdc.gov)
Women face great pressures through a range of gender-based disadvantages, and huge numbers experience physical and sexual violence, resulting in high rates of depression and anxiety disorders. (who.int)

But mumps is back, and is having its worst year in a decade, fueled in part by its spread on college campuses. (medicalxpress.com)
TED: Ideas worth spreading , Becky Blanton: The year I wa. (lingq.com)

During a past Daily Show episode, Jon Stewart responded to President Obama's statement that "this is America: we don't do what's easy, we do what's necessary" by holding up a jar of Baconnaise (bacon spread for sandwiches). (pursuit-of-happiness.org)

For the purposes of this article, I want to focus on one of the methods (max effort) and a particular population, specifically lifters that struggle with anxiety and/or depression. (elitefts.com)

Incentives exist for improving approaches to the prevention and spread of this infection. (umn.edu)
Previous reports have noted depression after West Nile virus (WNV) infection. (cdc.gov)

In other words, the results indicate that a healthy mood spreads through social networks, but depression does not. (socialworktoday.com)

US history textbook authors remain badly out of touch with the economic literature about the Depression. (joeyhudson.com)

Dr. Karen DeCocker joined us to share important things you need to know this National Depression and Mental Health Awareness Screening Month. (wgntv.com)

George Washington University Law School professor Dawn Nunziato held a presentation on Wednesday about social media's impact on the spread of medical and political falsehoods. (dailyfreepress.com)
Concerns about family/children, losing medical coupons, and feelings of depression/isolation were identified as challenges faced after diagnosis. (cdc.gov)

Anatomy14

Organisms3

Diseases18

Chemicals and Drugs26

Analytical, Diagnostic and Therapeutic Techniques and Equipment51

Psychiatry and Psychology97

Phenomena and Processes21

Disciplines and Occupations6

Anthropology, Education, Sociology and Social Phenomena22

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Great Depression13

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