Sprague dawley rats with clinical. Medical search. Frequent questions

Methods: Male Sprague-Dawley rats were pre-implanted with telemetry device and kept in the individual cages for recovery. (cdc.gov)
METHODS: Young (2-month-old) and old (24-month-old) Sprague-Dawley rats were subjected to splenectomy under isoflurane anaesthesia. (imperial.ac.uk)
METHODS: Bupropion was administered subcutaneously via osmotic minipumps over 2 days to determine its effects on the spontaneous firing activity of NE, serotonin (5-HT), and DA neurons in the brain of anaesthetised male Sprague-Dawley rats. (biopsychiatry.com)
While several potential remyelinating agents have proceeded to clinical trials, methods for accurately and non-invasively assessing changes in remyelination status remain limited. (nih.gov)
Methods: Female Sprague-Dawley rats underwent BPNI or sham surgery and were evaluated 3, 7, 14, and 30 days post-BPNI (n = 8/group). (lu.se)
Methods: An acute rat liver injury model induced by D-galactosamine was used. (bvsalud.org)

First published by Food and Chemical Toxicology in September 2012, the article presented a two-year feeding study in rats, and reported an increase in tumors among rats fed genetically modified corn and the herbicide RoundUp. (wikipedia.org)

Male and female Wistar rats were subjected to test acute oral toxicity. (europa.eu)
Rattus norvegicus, Sprague-Dawley and Wistar strain white rats, strain 13 and Hartley guinea pigs, New Zealand white rabbits, A. peninsulae**** and A. speciosus**** (Japan) inoc im with Ap P-5 or P-7 76-118 virus develop antibody without clinical signs or detectable antigen in their organs (2,5). (cdc.gov)
However, HTN virus infects Wistar Fisher rats after adaptation. (cdc.gov)
Desk 1 summarizes problem and treatment dosages and amounts of lungs from Sprague-Dawley (research 1 to 9), Wistar, Dark brown Norway, and Lewis (research 10) rats (all men weighing 300C350 g) examined in 10 research. (scapca.org)

Neither low-dose (10 ng/kg/min) nor high-dose (150 ng/kg/min) treprostinil therapy attenuated elevations of RVSP and right ventricular hypertrophy in pulmonary hypertensive rats. (umsystem.edu)

According to Shomron 7 (2010), this field of the clinical pharmacology studies the contribution of genomes, transcriptomes and proteomes in determining drug-response phenotypes (safety and efficacy). (bvsalud.org)

A chief criticism was that each part of the study had too few rats to obtain statistically useful data, particularly because the strain of rat used, Sprague Dawley, develops tumors at a high rate over its lifetime. (wikipedia.org)
Saimiri sciureus inoc im with Ap P-3 of Lee strain (human isolate) develop FA antibody and most inoc animals develop clinical signs of varying severity. (cdc.gov)
Cercopithecus aethiops, Cebus apella, Callithrix jaccus, Maccaca mulatta, M. fasciculatus, S. sciureus, M. nemestrina, and Papio anubis inoc im with Ap P-5 76-118 or the 3rd A-549 TC passage of this virus, and Aotus trivirgatus inoc im with Ap P-3 Lee strain develop antibody with only occasional clinical signs or viremia (2,5). (cdc.gov)
Rats were housed strain-wise in pairs in ST cages, in groups of eight in Enriched Rat Cage System (ERC) equipped with a shelter and wall-hung ladders, and in groups of eight in four interconnected Scantainer(NOVO) cages (NOVO), equipped with shelves. (slu.se)
However, an HEV strain recently isolated from rats was unique and only distantly related to known strains ( 11 ). (cdc.gov)
In this in vivo study, the clinically isolated strain of S. aureus 17546 (t037) was selected to establish a biofilm-associated infection rat model, and baicalin and linezolid were used to treat the infection. (bvsalud.org)

For evaluation, we induced TBI in adult male Sprague-Dawley rats (n = 80) by lateral FPI. (nature.com)
Acute oral toxicity was evaluated in groups of 2 adult male albino Sprague-Dawley rats administered para-chlorotoluene by gavage as either a 1.0 or 10% volume/volume solution in corn oil or in undiluted form at dosage levels of 10, 31.6, 100, 316, 1000 or 3160 ul/kg. (epa.gov)

CFC-12 was tested by inhalation on Sprague-Dawley rats and Swiss Mice using whole body exposure. (europa.eu)

abstract = "Outbred, male Sprague-Dawley rats can be classified as either low or high cocaine responders (LCRs or HCRs, respectively) based on cocaine-induced locomotor activity in an open-field arena. (illinois.edu)

Male Sprague-Dawley rats were assigned into three groups: experimental (n=12), sham surgery (n=6) and control (n=6). (cns.org)

RAI rats were subjected to test acute oral toxicity. (europa.eu)
Acute inhalation toxicity of the test item has been investigated in male and female Tif: RAIf (SPF) rats (10 per sex). (europa.eu)
Acute dermal toxicity of the test item was tested in male and female Sprague-Dawley rats. (europa.eu)
Body weight showed normal increments and none of the animals had any clinical signs of toxicity. (doaj.org)
No abnormalities in clinical signs, terminal body and organ weights, or hematologic and serum chemistry were noted, and no gross or histopathologic lesions of systemic tissue toxicity were found in any treatment group at any time point studied. (hindawi.com)
In conclusion, a single intramuscular dose of C4 produced no acute or chronic systemic toxicity or inflammation in rats, suggesting that C4 may be toxicologically safe for clinical use in cancer brachytherapy. (hindawi.com)
Recent clinical evidence indicates a potential for skeletal muscle toxicity after therapy with HMG-CoA reductase inhibitors (HMGRIs) in man. (aspetjournals.org)
The high DAR species present in T-DM1 contribute to its toxicity and limit its clinical dose. (biorxiv.org)

The time courses of urinary sodium excretion, plasma aldosterone concentration and proteinuria were studied in male Sprague-Dawley rats treated with a single dose of either PAN or vehicle. (portlandpress.com)
Sodium-glucose co-transporter 2 inhibition does not alter the pressure natriuretic response in Sprague Dawley rats. (ed.ac.uk)
Sodium-glucose co-transporter 2 inhibitors (SGLT2i) increase sodium and glucose excretion and show clinical promise in reducing cardiovascular risk, even in non-diabetics. (ed.ac.uk)
Our objective was to induce pressure natriuresis in rats and measure sodium excretion during challenge with an SGLT2i. (ed.ac.uk)
Dive into the research topics of 'Sodium-glucose co-transporter 2 inhibition does not alter the pressure natriuretic response in Sprague Dawley rats. (ed.ac.uk)

An experimental model in which C4 is injected into the quadriceps femoris muscle of rats, which would allow evaluation of local tissue tolerance and recovery from of any damage, and accurate assessment of local and systemic inflammation was used. (hindawi.com)
Sprague Dawley Rats were randomly divided into non-prediabetic group (NPD) and pre-diabetic group (PD) (n=6, per group) over a 20-week induction period and a further 12-week experimental period to get 32 weeks. (researchsquare.com)
The present study aimed to further explore the effect of Genistein on the development of the reproductive system of experimental rats. (elsevierpure.com)
CONCLUSION: Post-weaning exposure to Genistein could affect the development of the reproductive system of ovarian-intact experimental rats because of its action on the hypothalamic-pituitary-gonadal axis by regulating hormones and estrogen receptors. (elsevierpure.com)
In conclusion, ENaC mRNA expression, especially αENaC, is increased in the very early phase of the experimental model of PAN-induced nephrotic syndrome in rats, but appears to escape from the regulation by aldosterone after day 3. (portlandpress.com)
There are only a few experimental orthotopic models of glioblastoma for pre-clinical testing. (elsevierpure.com)

The young rats were treated with the TAK1 inhibitor takinib or the RIPK1 inhibitor necrostatin-1 (Nec-1) before surgery, and old rats received adeno-associated virus (AAV)-TAK1 before surgery. (imperial.ac.uk)
RESULTS: Old rats had low TAK1 expression and were more susceptible to surgery-induced POCD and neuroinflammation than young rats. (imperial.ac.uk)
TAK1 inhibition exacerbated surgery-induced pRIPK1 expression, neuroinflammation and cognitive dysfunction in young rats, and this effect was reversed by a RIPK1 inhibitor. (imperial.ac.uk)
We therefore investigated the impact of global brain hypoxia-ischemia on the thalamic circuit function in the somatosensory system of young rats. (cdc.gov)

We have isolated a genetically similar HEV from urban rats in Los Angeles, California, USA, and characterized its ability to infect laboratory rats and nonhuman primates. (cdc.gov)
We studied their seroepidemiology but were unable to obtain genomic sequence or to transmit an agent to laboratory rats. (cdc.gov)
Subsequently, in collaborations with the County of Los Angeles Department of Health (Los Angeles, CA, USA) Vector Management Program, we succeeded in transmitting to laboratory rats 2 strains of HEV from rats from Los Angeles but were again unable to obtain genomic sequence ( 14 ). (cdc.gov)

Viremia was higher in nude rats. (cdc.gov)

The results demonstrated that Cd exposure disrupted the balance between the blood and intestinal flora in Sprague-Dawley (SD) rats, with a significant increase in gut microbiota ( Clostridia_UCG_014 , NK4A214_group ) and blood microbiome ( Corynebacterium , Muribaculaceae ). (frontiersin.org)
The term intestinal pseudo-obstruction denotes a syndrome characterized by a clinical picture suggestive of mechanical obstruction in the absence of any demonstrable evidence of such an obstruction in the intestine. (medscape.com)

In the present study, we investigated the effects of Cd exposure on microbiota and serum metabolism in rats by omics analysis. (frontiersin.org)
After behavioral tests were completed, serum, feces, and hippocampal tissue of rats were collected. (medscimonit.com)
In the present study, we provided novel data that suggested atorvastatin could decrease the AGEs-induced increase in serum level of AGEs and suppress the expression of RAGE of aorta in Sprague Dawley (SD) rat models in euglycemic conditions. (biomedcentral.com)

The purpose of this study is to elucidate the effects of treprostinil on right ventricular systolic pressure (RVSP), right ventricular hypertrophy and vascular remodeling in a rat model of MCT-induced pulmonary hypertension. (umsystem.edu)
This study investigated the activity of the HPA axis in selected markers of glucose handling, and the stress response relative to components of the HPA axis in a diet-induced pre-diabetic rat model. (researchsquare.com)
The hypertension and insulin resistance typical of the hypertensive rat model were not influenced by an increased home cage activity. (slu.se)
To evaluate the interaction between HMGRIs and CsA, a rat model of CsA-induced cholestasis was developed. (aspetjournals.org)
The present study aimed to observe the effects of the BY + EA combination in a COPD rat model and dissect the potential mechanisms via Toll-like receptor (TLR) 4/nuclear factor kappa B (NF- κ B) signaling. (hindawi.com)
To research the consequences of LT and ET on vascular permeability on the body organ level, we utilized an isolated perfused rat lung model. (scapca.org)
Sprague-Dawley isolated perfused lung model research rat. (scapca.org)
In the present investigation, we successfully implanted rat C6 cells via intracranial stereotaxic cannulation in adult Sprague-Dawley rats for development and histoimmunopathological characterization of an advanced orthotopic glioblastoma allograft model, which could be useful for investigating the course of glioblastoma development as well as for testing efficacy of new therapeutic agents. (elsevierpure.com)
Our investigation indicated the successful development of intracranial cannulated orthotopic glioblastoma allograft in adult Sprague-Dawley rats, making it as a useful animal model of glioblastoma for pre-clinical evaluation of various therapeutic strategies for the management of glioblastoma. (elsevierpure.com)

The present study was undertaken to evaluate the potential adverse effects of 2-BP on pregnant dams and embryo-fetal development after maternal exposure during the gestational days (GD) 6 through 19 in Sprague-Dawley rats. (kjvr.org)

1999. Oxidative damage to the lipids and proteins of the lungs, testis and kidney of rats during carbon tetrachloride intoxication. (cdc.gov)
In your final research, we also examined LT in lungs prepared from various other rat strains insensitive or private to lethal ramifications of LT. Strategies and Components Pet treatment. (scapca.org)

Results of pharmacokinetic studies in rats treated with various HMGRIs +/- CsA indicated that coadministration of CsA alters the disposition of these compounds, resulting in increased systemic exposure (e.g., increased area under the plasma drug concentration vs. time curve-AUC) and consequent (up to 13-fold) increases in skeletal muscle drug levels. (aspetjournals.org)
In light of the above findings, it appears that HMGRI-induced myopathy is a class effect in the rat, which is potentiated by CsA as the result of altered clearance and resultant increased tissue exposure. (aspetjournals.org)
CAT-01-106 also showed improved pharmacokinetics in rats relative to T-DM1, with 40% higher ADC exposure levels. (biorxiv.org)
Together, the data suggest that CAT-01-106 may be sufficiently tolerable to enable clinical dosing at trastuzumab-equivalent exposure levels, combining the functions of both the antibody and the payload in one drug and potentially improving patient outcomes. (biorxiv.org)

In male rats, TRAP significantly increased hippocampal neurogenesis, while in females, TRAP increased granule cell layer width. (nature.com)
In addition, the rats supplemented with BB and SB diets showed increased hippocampal neurogenesis and expression of insulin-like growth factor 1, although the improvements in working memory performance could not solely be explained by these increases. (cambridge.org)

No adverse effects were observed in a 2-year chronic study in rats administered 15 or 150 mg/kg/day by gavage. (europa.eu)
In the same study as above, six groups of F344 rats (20 per sex per dose) received MCA (as an acid in deionized water) by gavage at 0, 30, 60, 90, 120 or 150 mg/ kg bw per day, 5 days per week, for 13 weeks. (canada.ca)
exposed Sprague-Dawley rats by munity long before cohort-based NHL and other lymphoprolifera- gavage. (who.int)

This study concluded that the three crops caused liver, kidney and heart damage in the rats. (wikipedia.org)
This study investigates the acute, subacute and chronic effects of a commercial TA coffee in Sprague Dawley rats when given in a single, repeated and prolonged dosage. (doaj.org)
This study was conducted to investigate the possible role of TAK1/RIPK1 signalling in POCD development following surgery in rats. (imperial.ac.uk)
They conducted their study on Sprague Dawley rats. (technologynetworks.com)
Thus, the present study was carried out to examine these mechanisms in aged animals by administering a control, 2 % SB- or 2 % BB-supplemented diet to aged Fischer 344 rats for 8 weeks to ascertain their effectiveness in reversing age-related deficits in behavioural and neuronal function. (cambridge.org)
This was a blinded, interventional pre-clinical study. (ed.ac.uk)
The aim of this study was to observe the direct impact of atorvastatin on advanced glycation end products- (AGEs) induced RAGE expression in healthy Sprague Dawley (SD) rats. (biomedcentral.com)

The in-life parameters measured were food and water intake, body weight and clinical observations. (doaj.org)

Sixty one plants reputed to have anti-fertility activity were tested on female Sprague-Dawley rats, in order to isolate active compounds with a potential for use in human fertility regulation. (who.int)

Although clinical studies show treprostinil to be a successful therapy for pulmonary hypertension, little information exists concerning the effects of treprostinil treatment in vivo. (umsystem.edu)
Studies establishing effectiveness included patients with NYHA Functional Class II-IV symptoms and etiologies of idiopathic or heritable PAH (58%), PAH associated with congenital systemic-to-pulmonary shunts (23%), or PAH associated with connective tissue diseases (19%) [see Clinical Studies ]. (rxlist.com)
Pulmonary function was markedly decreased in the COPD rats, and the lung tissue histology of the COPD rats showed severe pathological changes. (hindawi.com)
NEW & NOTEWORTHY The main findings from today's research are that lethal toxin boosts pulmonary artery pressure and pulmonary permeability separately Zileuton in the isolated rat lung, whereas edema toxin reduces the previous and will not boost permeability. (scapca.org)

Additionally, we found that treprostinil attenuated the induction of PPAR-[gamma] protein levels in whole lung homogenates of MCT-exposed rats. (umsystem.edu)
Sprague-Dawley rats, that are delicate to lethal ramifications of LT, had been utilized as lung donors for some experiments. (scapca.org)

In the Sprague-Dawley rat, very high, pharmacologically comparable dosages (150-1200 mg/kg/day) of structurally similar HMGRIs (lovastatin, simvastatin, pravastatin and L-647, 318) produced dose-related increases in the incidence and severity of skeletal muscle degeneration. (aspetjournals.org)

CAT-01-106 showed superior in vivo efficacy compared to T-DM1 at equal payload dosing and was equally or better tolerated compared to T-DM1 at equal payload dosing up to 120 mg/kg in Sprague-Dawley rats and 60 mg/kg in cynomolgus monkeys. (biorxiv.org)

Our findings show that the initial locomotor response to cocaine can predict CPP in male Sprague-Dawley rats under conditions when place conditioning develops, and that LCRs may be more prone to develop conditioning in the context of cocaine reward. (illinois.edu)

A genetically distinct HEV was recently isolated from rats in Germany, and its genome was sequenced. (cdc.gov)

To assess the developmental neurotoxicity of more realistic TRAP exposures, we exposed male and female rats during gestation and early postnatal development to TRAP drawn directly from a traffic tunnel in Northern California and delivered to animals in real-time. (nature.com)
Evaluation of the potential interaction between the HMGRI, lovastatin and CsA at the level of hepatic microsomal metabolism indicated that CsA did not inhibit the metabolism of lovastatin in isolated microsomes from female rats. (aspetjournals.org)

In this experiment, Sprague-Dawley rats were randomly divided into 4 groups: control, chronic unpredictable mild stress (CUMS), acupuncture, and fluoxetine groups. (medscimonit.com)
The increased levels of the inflammatory cytokines interleukin (IL)-1 β and IL-6 indicated a chronic inflammatory state in the COPD rats. (hindawi.com)
[ 1 ] On the basis of the clinical presentation, pseudo-obstruction syndromes can be divided into acute and chronic forms. (medscape.com)

It concluded that MON 863, a corn rootworm-resistant Bt corn developed by Monsanto, caused health problems in rats, including weight changes, triglyceride level increases in females, changes in urine composition in males, and reduced function or organ damage in the liver, kidney, adrenal glands, heart and haematopoietic system. (wikipedia.org)

Acute Oral Dose Range-rats with Cover Letter Dated 06/25/1987. (epa.gov)
This treatment was used in order to obtain levels of the parent compound and its putatively active metabolites that would more adequately reflect the clinical condition than utilizing acute injections. (biopsychiatry.com)

Acupuncture, which has many good effects and few adverse effects, is widely recognized as an alternative therapy for depression in clinical practice. (medscimonit.com)
This paper aims to discuss the relationship between pharmacogenomics and dental practice, focusing on clinical implications and current researches. (bvsalud.org)

CONCLUSION: Ageing-related decreases in TAK1 expression may contribute to surgery-induced RIPK1 overactivation, resulting in neuroinflammation and cognitive impairment in old rats. (imperial.ac.uk)

Our previous mRNA-seq data revealed a 1.8-2.5 fold increase in clusterin mRNA expression in lesioned brain areas in rats with lateral fluid-percussion injury (FPI)-induced TBI. (nature.com)

The rats were treated daily for three weeks from postnatal day 22 (P22) to P42. (elsevierpure.com)

Finally, treprostinil significantly lowered PPAR-[gamma] protein expression in MCT-exposed rats. (umsystem.edu)

At the highest regimen, the mean firing rate of 5-HT neurons was 100% higher than in control rats, but unaffected in NE-lesioned rats. (biopsychiatry.com)
We used single neuron recordings and controlled whisker deflections to examine responses of thalamocortical neurons to sensory stimulation in rat survivors of 9 min of asphyxial cardiac arrest incurred on post-natal day 17. (cdc.gov)

Hyperglycemic rats showed diabetic complications including polydipsia, polyuria, glycosuria, renal hypertrophy and increased glomerular filtration rate. (nih.gov)
Atorvastatin can downregulate the expression of receptor for advanced glycation end products (RAGE) in the aortas of diabetic rats. (biomedcentral.com)

The animals were exposed by inhalation, 4 hours daily, 5 days weekly, for 104 weeks (rats: Exp. (europa.eu)
Thus, based on dosimetric relationships, determinants of airway injury sites following inhalation extrapulmonary airway injury in the rat may be predictive of intrapulmonary airway injury in humans. (cdc.gov)

Mortality was observed in both rats in the 3160 ul/kg dose group (100% solution) and the LD50 was estimated to be 1780 ul/kg. (epa.gov)
During the test period, clinical signs, mortality, body weights and food consumption were examined. (kjvr.org)

Interim evaluations were done on five rats per dose group after 4 and 8 weeks of treatment. (canada.ca)

The results showed that rats consuming the berry diets exhibited enhanced motor performance and improved cognition, specifically working memory. (cambridge.org)
These results suggest that a 14-day subcutaneous dose of 2-BP is embryolethal and teratogenic at above 750 mg/kg/day in pregnant rats. (kjvr.org)

The relative amounts of αENaC, βENaC and γENaC mRNAs were determined in kidneys from these rats by real-time quantitative TaqMan PCR, and the amounts of proteins by Western blot. (portlandpress.com)

In contrast, when cocaine was administered by the i.v. route, the LCR/HCR classification not only predicted sensitization, but also CPP, with only LCR rats exhibiting sensitization and cocaine conditioning. (illinois.edu)

The data included three rat-feeding studies published by Monsanto scientists on MON 810. (wikipedia.org)
The prognostic significance of HRV in cardiovascular disease has been reported in clinical and epidemiological studies. (cdc.gov)
Longevity studies in rats. (avma.org)
HMG-CoA reductase inhibitor-induced myopathy in the rat: cyclosporine A interaction and mechanism studies. (aspetjournals.org)
Malaria in pregnancy (MiP) studies assessing the clinical performance of highly sensitive rapid diagnostic tests (HS-RDT) for Plasmodium falciparum detection. (cdc.gov)

The French Society of Toxicologic Pathology pointed out that, because such tumors are commonly found in older rats, the inclusion in the article of those images from treated rats, without also showing control rats, was misleading. (wikipedia.org)
Additional benefits of the alternative cages are qualitative, since they stimulate a wider range of behaviours, social interactions and offer possibilities for the rats to control their situation. (slu.se)
Method:Ninety healthy, male Sprague Dawley rats were randomly divided into three groups of control (I), coldexposed (II), and cold exposed with ascorbic acid 500 mg/L supplementation mixed in drinking water(III). (edu.pk)

Blood were collected for hematology and clinical biochemistry analyses. (doaj.org)

At the press conference, Séralini emphasized the study's potential cancer implications, and photographs from the article of treated rats with large tumors were widely circulated by the media. (wikipedia.org)

Clinical trials showed a marked difference in patients with heart conditions when specific servings of astragalus root extract were given. (wakeup-world.com)
Despite a large number of favourable preclinical proof-of-concept trials, no clinical treatments are yet available to improve post-TBI outcome 5 . (nature.com)

The test chemical was administered subcutaneously to pregnant rats at dose levels of 0, 375, 750 and 1250 mg/kg/day. (kjvr.org)

In addition, there was no attenuation of medial wall thickening when MCT-exposed rats also received treprostinil treatment. (umsystem.edu)
Our HfO2 nanoparticles are far more efficient at killing the bacteria and reducing the biofilm burden both in cell cultures of bacteria and in [infected] rats," said Ostadhossein, noting that their new technology is also much safer than conventional treatment. (technologynetworks.com)
In the second phase, normal and hyperglycemic Sprague Dawley rats were fed on skin, flesh and whole fruit of bitter melon at 150 and 300 mg/kg body weight and assessed for diabetes prophylaxis and treatment. (nih.gov)
SD rats received AGE-BSA (20 mg/kg/day or 40 mg/kg/day), dual treatment (AGE-BSA 40 mg/kg/day and atorvastatin 20 mg/kg/day) or no treatment for 12 and 24 weeks, respectively. (biomedcentral.com)

Circulating antibodies detected in sera of infected rats (21). (cdc.gov)
Rats are particularly interesting as a potential source of human infections because although they are not a human food, they have a high seroprevalence of antibodies against HEV ( 12 , 13 ) and they are ubiquitous and in close contact with humans everywhere. (cdc.gov)

The most potent dose was 300 mg/kg whole fruit that resulted in 31.64% lowering of blood glucose level and 27.35% increase in insulin level in hyperglycemic rats. (nih.gov)

Progress in the preclinical and clinical development of neuroprotective and antiepileptogenic treatments for traumatic brain injury (TBI) necessitates the discovery of prognostic biomarkers for post-injury outcome. (nature.com)
The orthotopic glioblastoma allograft was generated by intracerebral injection of rat C6 cells through a guide-cannula system and after 21 post-inoculation days the brain tumor was characterized by histoimmunopathological experiments. (elsevierpure.com)

At week four after device implantation, rats were exposed to MWCNTs for 5h at a concentration of 5 mg/m3. (cdc.gov)

Anatomy16

Organisms12

Diseases10

Chemicals and Drugs33

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Psychiatry and Psychology4

Phenomena and Processes28

Disciplines and Occupations1

Technology, Industry, Agriculture1

Health Care3

Methods6

Toxicology1

Wistar4

Hypertensive rats1

Pharmacology1

Strain6

Adult male2

Mice1

Abstract1

Sham surgery1

Toxicity8

Sodium5

Experimental6

Young rats4

Laboratory rats3

Viremia1

Intestinal2

Serum3

Model9

Gestational1

Lungs2

Exposure4

Hippocampal neurogenesis2

Gavage3

Study7

Observations1

Isolate1

Pulmonary4

Lung2

Dosages1

Vivo1

Develops1

Genetically1

Female2

Chronic3

Liver1

Acute2

Practice2

Conclusion1

MRNA1

Postnatal1

Protein expression1

Neurons2

Diabetic2

Inhalation2

Mortality2

Dose group1

Results2

Amounts1

Sensitization1

Studies5

Control3

Biochemistry1

Tumors1

Trials2

Pregnant1

Treatment4

Antibodies2

Insulin1

Brain2

Concentration1