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  • CARBON
  • It is worthwhile to stand out the natural occurring and synthetic cyclic alkaloids which contain a nitrogen atom adjacent to the spiro carbon. (iucr.org)
  • spirocyclic
  • The first spirocyclic GP inhibitor (GPI), a glucopyranosylidene-spiro-hydantoin ( A , X = O in Chart 1 ) was disclosed in the mid-nineties [ 17 ] followed by the more easily synthesized thiohydantoin counterpart ( A , X = S) [ 18 , 19 ]. (mdpi.com)
  • The title compound, 1'-(benzyloxy)-5'-cyanomethyl-2,3-dihydrospiro [inden-1,2'-pyrrolidine], ( trans-IIIa ), belongs to the family of spirocyclic compounds. (iucr.org)
  • substituents
  • Similar studies with compounds B concluded that bulky substituents such as the 2-naphthyl moiety (marked in blue) better contributed to the binding even in the absence of the hydrogen bonding β-NH and the carbonyl in the α-position [ 22 ]. (mdpi.com)
  • comprise
  • Di-D-fructose dianhydrides (DFAs) comprise a unique family of stereoisomeric spiro-tricyclic disaccharides formed upon thermal and/or acidic activation of sucroseand/ or D-fructose-rich materials. (mdpi.com)
  • molecular
  • Bis-spiropyrans contain two photochromic spiropyran units in the molecule and achievable opening of two pyran cycles allow one to suggest such compounds as a prototypes for the multistate light-driven molecular switches [ 7 ] that can be controllably and reversibly switched between three or more well-distinguished states. (hindawi.com)
  • synthetic
  • It should be pointed out that studies in this area of research are aimed mostly on the 1,3,3-trimethylindoline-based structures [ 2 , 8 ] due to well-known synthetic and purification techniques for such compounds. (hindawi.com)
  • mixture
  • From the reaction of a monoprotected cyclohexane-1,4-dione 5 with the allylic hydroperoxide 6 derived from the singlet oxygenation of methyl hydroxytiglate, one monospiro compound was obtained, the 1,2,4-trioxane ketone 7, as well as a mixture of the diastereoisomeric syn- and anti bis-1,2,4-trioxanes 8. (mdpi.com)
  • various
  • This phenomenon is a well-known disadvantage of spiropyran-like compounds, and various approaches are discussed to stabilize an open chain-like isomers and to reduce influence of reverse bleaching-cyclization reaction. (hindawi.com)
  • process
  • A process for preparing substituted pentacene compounds comprises the step of cyclizing substituted bis(benzyl)phthalic acids using an acid composition comprising trifluoromethanesulfonic acid, the substituted bis(benzyl)phthalic acids b. (sumobrain.com)
  • range
  • Both compounds were active as GPIs in the low micromolar concentration range. (mdpi.com)
  • One can obviously understand that such approach significantly narrows the range of possibly achievable characteristics of spiro-compounds. (hindawi.com)
  • forms
  • Forms of (2-cyclopropyl-6-(3,5-dimethylisoxazol-4-yl)-1H-benzo[d]imidazol- -4-yl)di(pyridin-2-yl)methanol (Compound I) were prepared and characterized in the. (patents.com)
  • As a result of theoretical modeling and photochemical experiments, it was shown that obtained compounds are perspective prototypes for multistate light-driven switches with improved stability of photoinduced forms. (hindawi.com)
  • Similar
  • Nevertheless, cell growth inhibition and gene expression profiling experiments revealed that the three compounds have quite similar potency against the tumor cell lines tested in this study. (biomedsearch.com)
  • known
  • A new anti-inflammatory active flavanone glycoside 5,7-dihydroxy-8,4 -dimethoxyflavanone-5-O-a-l-rhamno -pyranosyl-7-O-b-d-arabinopyranosyl-(1 4 )-O-b-d-glucopyranoside A along with a known compound dihydroquercetin-4 ' -methyl ether B have been isolated from the leaves of Echinops echinatus . (niscair.res.in)
  • Application
  • Compounds of this type are usable for obtaining of new smart materials with controlled characteristics that are perspective for application in many areas [ 3 - 6 ]. (hindawi.com)
  • different
  • TDDFT-ECD calculations could efficiently distinguish the proposed epimeric products having different absolute configuration in the spiro heterocyclic ring. (mdpi.com)
  • chain
  • Two new compounds, a euphane triterpenoid, 20,22-epoxyeupha-24-ene-3-one and a long chain compound, 5,6-epoxytridecanyl-1-[4 (5 ), 9 (10 )-ditetradecen], 13-[12 (13 )-pentadecen]-dioate were isolated from the oleo gum resin of the plant Boswellia serrata . (niscair.res.in)