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  • Tarlov
  • Neurologic function was evaluated using Tarlov ratings at 4 and 24 h after spinal-cord ischemia. (stopvivisection.info)
  • All animals were sacrificed after neurological evaluation with modified Tarlov criteria at the 48th hour after reperfusion, and the spinal cord segments (L4-6) were harvested for histopathological examination, biochemical analysis and terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling (TUNEL) staining. (biomedcentral.com)
  • Spinal cord function was assessed by motor evoked potentials (MEPs) and lower limb reflexes using a modified Tarlov score. (springeropen.com)
  • cord edema
  • In today's study, IPC considerably attenuated the consequences on I-R damage on bloodstream spinal cord hurdle permeability and spinal-cord edema at both 4 and 24 h after damage. (stopvivisection.info)
  • Evaluation of drinking water content showed equivalent outcomes, as I-R elevated drinking water content because of spinal-cord edema ( 0.01), while IPC attenuated this impact in 4 h ( 0.05) and 24 h ( 0.01), seeing that shown in Body 2H. (stopvivisection.info)
  • transection
  • However, some anamniotes including the zebrafish Danio rerio exhibit both sensory and functional recovery even after complete transection of the spinal cord. (jove.com)
  • cerebrovascular
  • Disruption from the bloodstream brain barrier takes place under several pathological conditions, such as for example Itga1 stroke and spinal-cord damage, leading to an elevated cerebrovascular permeability with following development of tissues edema . (stopvivisection.info)
  • novel
  • A combination of a non-hypotensive dose of 1,25 D and resveratrol can be a novel and effective strategy for protecting against ischemia. (greenmedinfo.com)
  • induce
  • The major advantage of this method is to facilitate location of the left anterior descending artery (LAD) to allow for accurate ligation of this artery to induce ischemia in the left ventricle of the mouse heart. (jove.com)
  • cardiac
  • Ding X, Ardell JL, Hua F, McAuley RJ, Sutherly K, Daniel JJ and Williams CA: Modulation of cardiac ischemia-sensitive afferent neuron signaling by preemptive C2 spinal cord stimulation: Effect on substance P release from rat spinal cord. (spandidos-publications.com)
  • additional comments toward the evaluation of cardiac function and remodeling by modifying the duration of reperfusion, is also presented. (jove.com)
  • surgery
  • No recent studies have analyzed the rates of or reasons for unanticipated revision surgery within 30 days of primary surgery in spinal deformity patients. (jove.com)
  • Of 2758 patients [aged 16.07 years (range, 2-71), 69.8% female] who underwent spinal fusion surgery, 59 (2.1%) required reoperation within 30 days after primary surgery. (jove.com)
  • cords
  • Histopathological analysis revealed that HSYA treatment attenuated I/R induced necrosis in spinal cords. (biomedcentral.com)
  • Further mRNA/lncRNA microarray analysis revealed that the expression profiles of lncRNA and mRNA in the spinal cords differed markedly between the control and 2 h groups, and in total 7,980 differentially expressed (>2‑fold) lncRNAs (234 upregulated, 7,746 downregulated) and 3,428 mRNAs (767 upregulated, 2,661 downregulated) were identified. (spandidos-publications.com)
  • treatment
  • As proven in Amount 3, ZO-1 amounts were reduced at 4 and 24 h after spinal-cord I-R damage, and IPC treatment attenuated this impact at both period factors ( 0 significantly.01). (stopvivisection.info)
  • stroke
  • Cerebral ischemia, or stroke, is the fifth leading cause of death in the United States, and the second highest cause of death globally. (medsci.org)
  • Evans Blue
  • As proven in Body 2, spinal-cord I-R damage CHIR-99021 irreversible inhibition caused a proclaimed increase in the quantity of Evans Blue dye extravasation weighed against sham handles, implying bloodstream spinal cord hurdle leakage. (stopvivisection.info)
  • damage
  • IPC Inhibits Bloodstream Spinal Cord Hurdle Breakdown after SPINAL-CORD I-R Damage Under physiological circumstances, the bloodstream brain hurdle and bloodstream spinal cord hurdle represent a good barrier between your circulating bloodstream and central anxious system, produced by dense restricted junction proteins, which seal the area between adjacent human brain endothelial cells. (stopvivisection.info)
  • role
  • TNF- α and IL-1) may play an important role in spinal cord IRI. (hindawi.com)
  • Here, we investigated the role of miR-129-5p after spinal cord IR, particularly in regulating high-mobility group box-1 (HMGB1) and the Toll-like receptor (TLR)-3 pathway. (biomedcentral.com)