• 37Metastatic spinal cord compression (MSCC) 38What is Metastatic spinal cord compression? (dokumen.tips)
  • Metastases can damage the bones around them, and around a quarter of those with metastatic prostate cancer develop a bone fracture. (wikipedia.org)
  • Design setting and participants: A cohort of 110 patients with prostate cancer who underwent surgery for metastatic spinal cord compression (MSCC) was analysed. (bvsalud.org)
  • Results and limitations: Patients with the myeloma-like metastatic pattern had median survival after surgery for MSCC of 1.7 (range 0.1-33) mo, while the median survival period of those with the non-myeloma-like pattern was 13 (range 0-140) mo (p (bvsalud.org)
  • Conclusions: A myeloma-like metastatic pattern identifies an important subtype of metastatic prostate cancer associated with poor survival and neurological outcomes after surgery for MSCC. (bvsalud.org)
  • Radiotherapy for acute metastatic epidural spinal cord compression (MESCC) involves conventional techniques and dose fractionation schemes, as it needs to be initiated quickly. (hindawi.com)
  • Metastatic epidural spinal cord compression (MESCC) is a common neurological complication of cancer and can have devastating consequences for patients [ 1 - 3 ]. (hindawi.com)
  • Malignant spinal cord compression (MSCC) is defined as the compression of the dural sac and its contents (spinal cord or cauda equina) by an extradural or intradural mass, which may lead to irreversible neurological damage such as paraplegia or tetraplegia depending on the level of the lesion. (palcareindia.com)
  • Growing metastases can also compress the spinal cord causing weakness in the legs and feet, or limb paralysis. (wikipedia.org)
  • Background: Prostate cancer spinal bone metastases can have a radiographic profile that mimics multiple myeloma. (bvsalud.org)
  • Spinal bone metastases were classified as myeloma like (n = 20) or non-myeloma like (n = 90) based on magnetic resonance imaging prior to surgery. (bvsalud.org)
  • However, to our knowledge, the use of this technique to treat spinal metastases, including MESCC, has not previously been reported. (hindawi.com)
  • In most cases, cord damage occurs due to an extension of vertebral body metastasis into epidural spaces, but damage can be due to vertebral collapse, direct metastasis through the intervertebral foramen and due to obstruction of the vascular supply. (palcareindia.com)
  • However, you may be able to have a spinal (epidural) anaesthetic instead. (prostatecanceruk.org)
  • This type of cancer can cause severe bone thinning which causes extreme damage to the bones leading to fractures. (onco.com)
  • MSCC is common in multiple myeloma, cancers of breast, prostate and lung. (palcareindia.com)
  • The radiation damages the prostate cells and stops them dividing and growing. (prostatecanceruk.org)
  • Furthermore, elderly patients, especially octogenarians, might be more susceptible to neurological damage by MESCC and their health is also likely deemed as poor to allow them to recover. (hindawi.com)
  • Does this patient have a high likelihood of having MSCC? (palcareindia.com)
  • This patient was treated with image-guided 3DCRT (IG-3DCRT) alone using a FIF technique and a unique hypofractionated dose fractionation scheme, which resulted in good tumor control and sufficient cord decompression, which in turn allowed a delayed but gradual improvement in her severe neurological dysfunction. (hindawi.com)
  • As the tumor grows, it can damage nearby organs causing erectile dysfunction, blood in the urine or semen, and trouble urinating. (wikipedia.org)
  • The risk of developing MSCC is high when the cancer has spread to the bones. (onco.com)
  • The myeloma-like appearance had an independent prognostic value for the risk of death after MSCC surgery (adjusted hazard ratio 2.4, p = 0.012). (bvsalud.org)
  • Maranzano and colleagues have reported over the past decade on the largest series of patients with malignant spinal cord compression (MSCC) treated in randomized trials. (medscape.com)
  • 4. Identifying patients with malignant spinal cord compression (MSCC) near end of life who can benefit from palliative radiotherapy. (nih.gov)
  • This study reviews information on 24 patients who developed a recurrence of spinal cord compression (4% of the entire study population of patients treated for MSCC) and on the 12 of those patients who received a second course of radiation. (medscape.com)
  • The data from the current study show that in a selected population of patients who develop a recurrence of MSCC in a previously treated field, retreatment can be given with good palliative effect and no increased risk for spinal cord damage from treatment. (medscape.com)
  • Patients with MSCC should have a multidisciplinary evaluation, if possible, at initial diagnosis as well as in the unfortunate event of a recurrent MSCC. (medscape.com)
  • Furthermore, thoracic cord level of injury is most frequent in these cases (Lee et al. (scireproject.com)
  • Maranzano and colleagues have mounted a series of randomized controlled trials looking at various radiation treatment strategies for MSCC. (medscape.com)
  • The targeted treatment means less damage is done to healthy surrounding tissues, which can also lead to fewer side effects. (prostatecanceruk.org)
  • MSCC is one of the true oncologic emergencies that face physicians who treat cancer. (medscape.com)
  • These viruses, known as enteroviruses, are common infections that everyone acquires over time, but only result in spinal cord damage in a very small proportion of the population (University of Minnesota Masonic Children's Hospital 2018). (scireproject.com)
  • Spontaneous spinal epidural hematomas refer to blood within the epidural space without known traumatic or iatrogenic cause and have an estimated incidence of 0.1 in 100,000 per year (Figueroa & DeVine 2017). (scireproject.com)