• (ovid.com)
  • Because there are many places on the dendrimer structure on which to attach gadolinium ions, it is possible to obtain a greater signal enhancement with dendrimer-based constructs than arises with small organic carriers, which in turn, could increase the sensitivity with which MR could detect the smallest tumors. (nanowerk.com)
  • Indeed, tests in animals found that the minimum detectable concentration for a dendrimer containing 64 gadolinium ions was 100-fold less than with a commercially available gadolinium MR contrast agent. (nanowerk.com)
  • Findings from this study suggested that MUC-1 targeted curcumin-loaded PEGylated Au dendrimers have good X-ray attenuation and is desirable probe for CT imaging while demonstrating high therapeutic index against colorectal cancer adenocarcinoma. (ovid.com)
  • Dendrimers are not only capable of delivering drugs or diagnostic agents to desired sites by encapsulating or conjugating them to the periphery, but also have therapeutic efficacy in their own. (readbyqxmd.com)
  • The company will seek for the full-scale development of the new dendrimer by further exploring its features and applications through joint research with our customers. (hakuto.co.jp)
  • While various applications can be expected including photoactive resins and rheology improving additives, Hakuto adopted the new dendrimer derivative for resin used in two-photon absorption laser stereolithography. (hakuto.co.jp)
  • The aim of the current study was to investigate the theranostic capability of curcumin-loaded dendrimer-gold hybrid structure. (ovid.com)
  • The general structure of a dendrimer. (horiba.com)
  • Since the dendrimer has hydroxyl groups at its ends, it is easy to be chemically modified. (hakuto.co.jp)
  • The more layers in the dendrimer the more effective it was due to the larger surface area. (medindia.net)
  • 1506. D.A. Tomalia, H.M. Brothers 2nd, L.T. Piehler, H.D. Durst, D.R. Swanson, "Partial shell-filled core-shell tecto(dendrimers): a strategy to surface differentiated nano-clefts and cusps," Proc. (molecularassembler.com)
  • Baker and his team also added the chemotherapy drug methotrexate to the dendrimers and injected them into mice with human epithelial-cell cancer. (blogspot.com)
  • Last February, Hakuto's Chemical Business Division established a technique to enable expeditious production of ester dendrimer through collaborative research with the National Institute of Information and Communications Technology (NICT) and announced its results. (hakuto.co.jp)
  • The results clearly showed that the larger dendrimer inhibited the abnormal activity of the protein best. (medindia.net)
  • As a first attempt for its application, Hakuto adopted a new dendrimer derivative for a newly-developed stereolithographic resin product. (hakuto.co.jp)
  • In the experiments we put certain amounts of these dendrimers and a control, with no dendrimers, into a protein solution for over 120 hours and stimulated aggregation with heat and shaking," she explained. (medindia.net)
  • Among them, the dendrimer is adopted for low viscosity and high precision types, and its full-scale deployment is slated before the end of this year. (hakuto.co.jp)