Time-of-flight maTandem Mass SpectroAspects of mass spectrometryAdvanced by mass spectrometryCoupled with mass spectrometryConference on Mass SpectrometrySmall molecule mass spectrometryPurification-mass spectrometryAtomic Absorption SpectrometryHPLCGamma SpectrometryAlpha-spectrometryChromatography-massMALDI TOFLund UniversityProteinsAnalysisDetectionQuantitativeAnalysesAffinityProteomicsDeterminationIdentificationScientistsPrinciplesPeptideFacilityAnalytical techniqueMethodMolecularApplicationsInstrumentationCharacterizationSensitivityProtein scienceClinicalDevelopmentsScienceSamplesMagneticExperimentalTechnologyDataOrganic
Time-of-flight ma6
- The product peptides derived from the endopeptidase activities of BoNTs are detected by matrix-assisted laser-desorption ionization time-of-flight mass spectrometry. (cdc.gov)
- Analysis of complex mixtures with gas chromatography coupled with high-resolution time-of-flight mass spectrometry (GC-HRTOFMS) can produce a large amount of data. (jeolusa.com)
- In this study, state-of-the-art instrumentation two-dimensional gas chromatography (GC × GC) coupled photoionization─time of flight mass spectrometry was employed to investigate the composition of dodecene products produced from olefin oligomerization. (jeolusa.com)
- Prospective Evaluation of a Matrix-assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry System in a Hospital Clinical Microbiology Laboratory for Identification of Bacteria and Yeasts: A Bench-by-bench Study for Assessing the Impact on Time to Identification and Cost-effectiveness. (beckmancoulter.com)
- Comparison of Two Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Methods with Conventional Phenotypic Identification for Routine Identification of Bacteria to the Species Level. (beckmancoulter.com)
- Trapped ion mobility spectrometry (TIMS) combined with quadrupole time of flight mass spectrometry (Q-TOF). (lu.se)
Tandem Mass Spectro3
- Cross-linking technology combined with tandem mass spectrometry (MS-MS) is a powerful method that provides a rapid solution to the discovery of protein-protein interactions and protein structures. (nih.gov)
- A team of scientists the Sports Medicine Research and Testing Laboratory at the University of Utah have developed a test that makes use of liquid chromatography-tandem mass spectrometry. (science20.com)
- A high-performance liquid chromatography-tandem mass spectrometry method for quantifying active toxin, where the amount of toxin can be correlated to the amount of product peptides, is also described. (cdc.gov)
Aspects of mass spectrometry2
- This conference brings together scientists interested in all aspects of mass spectrometry, from academia and industry including mass spectrometry vendors, big pharma, and small and medium enterprises developing instrumentation, software, services, and applications. (metabolon.com)
- Interpretation of mass spectra and data treatment will also be covered, together with practical aspects of mass spectrometry method development. (lu.se)
Advanced by mass spectrometry1
- An important impetus for the continuing exploration of Mars, Europa, Enceladus, Titan, and Venus involves assessing the habitability of solar system bodies and, ultimately, the search for life-a monumental effort that can be advanced by mass spectrometry. (frontiersin.org)
Coupled with mass spectrometry1
- We use gas chromatography (GC) to resolve complex mixtures of gases, and volatile and semi-volatile compounds, coupled with mass spectrometry (GC-MS) and other detectors such as flame ionisation (FID) and electron capture (ECD). (ncl.ac.uk)
Conference on Mass Spectrometry1
- Metabolon is proud to participate in the 71st ASMS Conference on Mass Spectrometry and Allied Topics being held in Houston, Texas from June 4 - 8, 2023. (metabolon.com)
Small molecule mass spectrometry1
- His doctoral work focused on development of new computational approaches towards small molecule mass spectrometry with a focus on microbial natural products drug discovery. (smith.edu)
Purification-mass spectrometry2
- Affinity purification-mass spectrometry and network analysis to understand protein-protein interactions. (nature.com)
- Here we used an affinity-purification mass spectrometry-based (AP-MS) approach to identify novel and particularly intracellular sGAG-interacting proteins in human bone marrow stromal cells (hBMSC). (degruyter.com)
Atomic Absorption Spectrometry1
- Atomic absorption spectrometry has many uses in different areas of chemistry. (just.edu.jo)
HPLC5
- The ability to couple mass spectrometry to other separation techniques such as capillary electrophoresis, GC, and HPLC makes it a versatile analytical tool for the simultaneous separation and identification of analytes. (sigmaaldrich.com)
- Is PNGase A compatible with downstream analysis such as HPLC and Mass Spectrometry? (neb.com)
- PNGase A is supplied in a glycerol-free storage buffer to allow for compatibility with downstream analysis such as HPLC and/or Mass Spectrometry due to the fact that glycerol is not tolerated in such instruments. (neb.com)
- this was followed by MALDI mass spectrometry (MS), which showed the presence of six or fewer resolved protein components above 20 kDa in each RP-HPLC fraction, giving a total of 93 MS resolved peaks. (unboundmedicine.com)
- TY - JOUR T1 - Characterization of wheat gluten proteins by HPLC and MALDI TOF mass spectrometry. (unboundmedicine.com)
Gamma Spectrometry2
- 4 stationary operating high-resolution gamma spectrometry units, ranging between 55 and 123% relative efficiency at 1332 keV for quantitative assay of gamma emitting radionuclides. (lu.se)
- Whole-body counter facility in low-background locality for in-vivo gamma spectrometry and internal dose assessment. (lu.se)
Alpha-spectrometry1
- 8 alpha spectrometry chambers chambers equipped with passivated implanted planar silicon (PIPS) detectors for the measurement of planar alpha source under vacuum. (lu.se)
Chromatography-mass1
- Gas chromatography mass spectrometry is also available for the analysis of volatile compounds, as well as a state-of-the-art pipetting robot for automated sample preparation. (lu.se)
MALDI TOF2
- MALDI-TOF mass spectrometry has emerged as a rapid, cost-efficient and clinically effective tool for identifying pathogens. (beckmancoulter.com)
- In this webinar, "The Use of MALDI-TOF in the Clinical Laboratory: Effectiveness and Challenges," Dr. Elizabeth Palavecino shares her laboratory's clinical experience with MALDI-TOF mass spectrometry. (beckmancoulter.com)
Lund University1
Proteins1
- In support of biotherapeutics across the board, KBI's Mass Spectrometry Core Facility has championed the characterization and management of proteins, active pharmaceutical ingredients (APIs), and impurities through identification, characterization, assessment, and quantitation. (kbibiopharma.com)
Analysis18
- Nanomechanical mass spectrometry has proven to be well suited for the analysis of high mass species such as viruses. (nature.com)
- Today, mass spectrometry is a well-established detection method that offers a multitude of benefits, such as selectivity, sensitivity, and multi-sample analysis. (sigmaaldrich.com)
- The environmental mass spectrometry laboratory has over 30 years of experience in the analysis of soil and sediments, and gas samples. (ncl.ac.uk)
- The environmental mass spectrometry laboratory can perform both routine and bespoke GC and GC-MS analysis with integrated liquid and pyrolysis autosamplers, and gas sampling valves. (ncl.ac.uk)
- Scientists at Purdue University, led by Graham Cooks, professor of analytical chemistry, recently reported a novel method for processing samples for mass spectrometry (MS) analysis. (the-scientist.com)
- This unique reference makes some of the esoteric aspects of this important area of analysis more readily comprehensible to those who deal with analytical instruments but who have not been trained in mass spectrometry. (wordtrade.com)
- Typical preparation steps include sectioning a sample into thin, flat slices because flatness is required to guarantee optimal laser focus, a key parameter in reliable analysis," Benjamin Bartels, the first author of the study and PhD student in the Mass Spectrometry Research Group, points out. (labmanager.com)
- Working at such small scales means it can be difficult to make different particles identical, and mass spectrometry could be a useful analysis to test the quality of the manufacturing. (cmu.edu)
- Mass spectrometry refers to the generation and analysis of ions according to their mass-to-charge. (purdue.edu)
- Describe the most common mass spectrometry applications, including possibilities and limitations for analysis. (lu.se)
- Carry out a mass spectrometry analysis and handle the aquired data using common mass spectrometry software. (lu.se)
- Practical parts including protein and peptide sample preparations, deposition with different techniques and the use of chromatographic separations for complex samples prior to mass spectrometry analysis. (lu.se)
- Title : Isothiazolinone Content of US Consumer Adhesives: Ultrahigh-Performance Liquid Chromatographic Mass Spectrometry Analysis Personal Author(s) : Goodier, Molly C.;Zang, Lun-Yi;Siegel, Paul D.;Warshaw, Erin M. (cdc.gov)
- This course covers modern mass spectrometry with a particular focus on the analysis of low molecular weight analytes. (lu.se)
- For accurate quantitative or qualitative analysis, mass spectrometry is today combined with different chromatographic techniques. (lu.se)
- Mass spectrometry for small molecules includes an overview of mass spectrometric techniques that can be used for analysis of low molecular weight analytes in both the gas and liquid phase. (lu.se)
- Practical parts include analysis of own or supplied samples by chromatography and mass spectrometry, with subsequent data analysis and identification of sample components. (lu.se)
- Proteomic analysis and discovery using affinity proteomics and mass spectrometry. (lu.se)
Detection2
- Detection and Identification of Explosives by Mass Spectrometry (D.D. Fetterolf). (routledge.com)
- Here, we delve into the search for extraterrestrial chemical and morphological biosignatures and examine several possible approaches to agnostic life detection using mass spectrometry. (frontiersin.org)
Quantitative2
- The Chalmers Mass Spectrometry Infrastructure (CMSI) is a Chalmers infrastructure with the goal of providing cutting edge and efficient quantitative mass spectrometry and structural identification analyses for researchers at Chalmers and beyond. (chalmers.se)
- α-spectrometry is used for qualitative and quantitative measurements of α-emitting radionuclides. (psi.ch)
Analyses3
- Chalmers Mass Spectrometry Infrastructure, CMSI, is a Chalmers infrastructure that provides access to mass spectrometry analyses to researchers both within and outside Chalmers. (chalmers.se)
- The infrastructure will provide a combination of service analyses and supported analyses for training students in analytical mass spectrometry. (chalmers.se)
- Forensic Applications of Mass Spectrometry combines the most current developments in applications of mass spectrometry techniques to forensic analyses. (routledge.com)
Affinity2
- Dunham, W.H., Mullin, M. & Gingras, A.C. Affinity-purification coupled to mass spectrometry: basic principles and strategies. (nature.com)
- Babu, M., Krogan, N.J., Awrey, D.E., Emili, A. & Greenblatt, J.F. Systematic characterization of the protein interaction network and protein complexes in Saccharomyces cerevisiae using tandem affinity purification and mass spectrometry. (nature.com)
Proteomics1
- Kocher, T. & Superti-Furga, G. Mass spectrometry-based functional proteomics: from molecular machines to protein networks. (nature.com)
Determination2
- Manual and automated mass spectrometry acquisition of intact protein and peptide mass determination and determination of peptide sequence information. (lu.se)
- Basic data handling of mass spectrometry data for protein identification, assessment of PTMs and determination of amino acid sequences. (lu.se)
Identification1
- Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. (nature.com)
Scientists3
- The seventh Berliner LC-MS/MS symposium includes a programme of talks about mass spectrometry methods and applications, from international researchers and analytical scientists. (foodnavigator.com)
- Over the past century, mass spectrometry development has been influenced by scientists from all disciplines. (purdue.edu)
- We are a service facility equipped with unique technology and experienced scientists in the field of mass spectrometry. (lu.se)
Principles1
- Describe the principles of mass spectrometry, including the basic design of the instrument and its operation. (lu.se)
Peptide1
- Make an experimental plan for preparing and analyzing protein and peptide samples using mass spectrometry. (lu.se)
Facility2
- KBI's state-of-the-art mass spectrometry core facility delivers unparalleled structural characterization services to our clients. (kbibiopharma.com)
- We recently sat down with Michael J. Nold, Ph.D., Senior Director of KBI's Mass Spectrometry Core Facility in Durham, North Carolina, to discuss how advanced Mass Spectrometry plays a significant analytical role in the characterization and quantitation of APIs and impurities in complex biotherapeutics. (kbibiopharma.com)
Analytical technique1
- Mass spectrometry (MS) is an analytical technique that uses mass-to-charge ( m/z ) ratio to identify compounds in a sample. (sigmaaldrich.com)
Method5
- Electron impact has remained the most widely used method of ionization in mass spectrometry. (britannica.com)
- Rapid immunoprecipitation mass spectrometry of endogenous protein (RIME) is a method that allows the study of protein complexes, in particular chromatin and transcription factor complexes, in a rapid and robust manner by mass spectrometry (MS). The method can be used in parallel with chromatin immunoprecipitation-sequencing (ChIP-seq) experiments to provide information on both the cistrome and interactome for a given protein. (nature.com)
- Mass Spectrometry Basics by Christopher G. Herbert, R. A. W. Johnstone (CRC Press) Provides authoritative yet plain-spoken explanations of the basic concepts of this powerful analytical method without elaborate mathematical derivations. (wordtrade.com)
- Laser ablation electrospray ionization (LAESI) is a method that can be applied in mass spectrometry imaging to investigate the distribution of many different chemical compounds found in a biological sample. (labmanager.com)
- 4 usually cause human botulism (A, B, E, and F). We developed a rapid, mass spectrometry-based method (Endopep-MS) to detect and differentiate active BoNTs A, B, E, and F. This method uses the highly specific protease activity of the toxins with target peptides specific for each toxin serotype. (cdc.gov)
Molecular2
- Due to the sensitivity of mass spectrometry, it is widely used to measure very low molecular weights at extremely low concentrations, below nanograms per milliliter (ng/mL). (sigmaaldrich.com)
- The IMS CORE Lab is included in the Division of Imaging Mass Spectrometry of the Maastricht MultiModal Molecular Imaging Institute M4I . (maastrichtuniversity.nl)
Applications4
- The evolution of mass spectrometry has been marked by an ever-increasing number of applications in science and technology. (britannica.com)
- Forensic Applications of Pyrolysis-Mass Spectrometry (T.O. Munson). (routledge.com)
- Mass Spectrometry Basics describes processes, applications, and the underlying science in a concise manner supported by figures and graphics to further comprehension. (wordtrade.com)
- Glycoprotein Denaturing Buffer (containing SDS and DTT) is not compatible with Mass Spectrometry applications, and often times hard to remove from the reaction. (neb.com)
Instrumentation2
- Tutorial book on mass spectrometry, instrumentation and mainly fragmentation of organic compounds. (nist.gov)
- The book starts with an in-depth description of the theory and current instrumentation of FT-IR spectrometry, with full chapters devoted to signal-to-noise ratio and photometric accuracy. (ellibs.com)
Characterization2
- Mass spectrometry is among the most powerful analytical techniques available for protein characterization. (kbibiopharma.com)
- Advanced analytical capabilities, including mass spectrometry, are critical for the characterization of active pharmaceutical ingredients (APIs) and managing a diverse population of impurities. (kbibiopharma.com)
Sensitivity1
- The prevalence of mass spectrometry in every corner of science is due to its high selectivity and sensitivity, wide chemical scope and to its adaptable nature. (purdue.edu)
Protein science1
- The course gives an introduction in how to use protein mass spectrometry as a tool in protein science. (lu.se)
Clinical2
- Mass spectrometry is widely used across many research fields and industries, including the pharmaceutical and food industries, health clinics, clinical research labs, and forensic and environmental testing labs. (sigmaaldrich.com)
- Dr. Elizabeth Palavecino is professor of pathology, director of clinical microbiology and co-director of the clinical and translational mass spectrometry center at Wake Forest School of Medicine. (beckmancoulter.com)
Developments1
- The event includes a plenary session on trends and new developments in mass spectrometry, followed by an afternoon of talks divided into six parallel themes. (foodnavigator.com)
Science1
Samples3
- Custom-built laser source for mass spectrometry imaging: By means of improved Laser Ablation Electrospray Ionization (LAESI) the surfaces of non-flat samples-for example this coarse piece of savoy cabbage-can now be chemically analyzed. (labmanager.com)
- Benjamin Bartels and Aleš Svatoš, who heads the Mass Spectrometry Research Group, have therefore adapted the LAESI technique to non-flat surfaces to open up the possibility of performing chemical imaging of samples with pronounced three-dimensional shapes while maintaining the reliability of classical measurements. (labmanager.com)
- High-resolution mass spectrometry is a powerful tool used at KBI Biopharma for analytical strategies concerning complex samples. (kbibiopharma.com)
Magnetic1
- Magnetic resonance (MR) spectrometry and PET scan (positron emission tomography). (medscape.com)
Experimental1
- Designed to help practitioners using FT-IR capitalize on the plethora of techniques for modern FT-IR spectrometry and plan their experimental procedures correctly, this is a practical, hands-on reference for chemists and analysts. (ellibs.com)
Technology1
Data1
- PLS wavelength selection treatment is performed on the data obtained by attenuated total reflectance Fourier transform infrared spectrometry in 830-1800 cm −1 wavenumber range. (hindawi.com)
Organic1
- The work discussed herein chronicles the integration of mass spectrometry into the home, the clinic and the process organic lab. (purdue.edu)