• Tyrosine kinase inhibitors (TKIs) are currently approved for the treatment of metastatic renal cell carcinoma (mRCC). (biomedcentral.com)
  • Renal cell carcinoma (RCC) accounts for 2% of all cancers. (urotoday.com)
  • RCC, renal cell carcinoma. (urotoday.com)
  • The median ages of the patients with urothelial cancer (UC) and renal cell carcinoma (RCC), but not the median age of those with prostate cancer (PC), were significantly increased between the study periods. (bvsalud.org)
  • BACKGROUND: This study compared real-world outcomes of metastatic renal-cell carcinoma (mRCC) patients treated with tyrosine kinase inhibitors or nivolumab plus ipilimumab. (bvsalud.org)
  • The large, rapidly Gemcitabine HCl novel inhibtior growing nodules of malakoplakia may mimic renal cell carcinoma in imaging studies. (buyresearchchemicalss.net)
  • A unifocal renal lesion is usually uncommon and can resemble a necrotic renal cell carcinoma [1]. (buyresearchchemicalss.net)
  • Histological examination of the nephrectomies carried out in our department revealed mainly chronic non-specific pyelonephritis in 24 (35.3%) patients, followed by renal cell carcinoma in 23 (33.82%) patients and urothelial carcinoma in 9 (13.2%) patients. (springeropen.com)
  • 2007) Patterns of recurrence and surveillance strategies for renal cell carcinoma following surgical resection. (medscape.org)
  • 1999) Nephron sparing surgery for localized renal cell carcinoma: impact of tumor size on patient survival, tumor recurrence and TNM staging. (medscape.org)
  • 2004) Nephron sparing surgery for appropriately selected renal cell carcinoma between 4 and 7 cm results in outcome similar to radical nephrectomy. (medscape.org)
  • 1994) Expanding indications for conservative renal surgery in renal cell carcinoma. (medscape.org)
  • 1969) The results of radical nephrectomy for renal cell carcinoma. (medscape.org)
  • 2004) Changing concepts in the surgical management of renal cell carcinoma. (medscape.org)
  • 2000) Long-term results of nephron sparing surgery for localized renal cell carcinoma: 10-year followup. (medscape.org)
  • 2004) Application of TNM, 2002 version, in localized renal cell carcinoma: is it able to predict different cancer-specific survival probability? (medscape.org)
  • 2005) Elective nephron sparing surgery should become standard treatment for small unilateral renal cell carcinoma: long-term survival data of 216 patients. (medscape.org)
  • 2005) Assessment of surgical margins in renal cell carcinoma after nephron sparing: a comparative study: laparoscopy vs open surgery. (medscape.org)
  • 1989) Conservative surgery for renal cell carcinoma: a single-center experience with 100 patients. (medscape.org)
  • Licht MR and Novick AC (1993) Nephron sparing surgery for renal cell carcinoma. (medscape.org)
  • 1997) Patterns of tumor recurrence and guidelines for followup after nephron sparing surgery for sporadic renal cell carcinoma. (medscape.org)
  • Vermooten V (1950) Indications for conservative surgery in certain renal tumors: a study based on the growth pattern of the cell carcinoma. (medscape.org)
  • Renal cell carcinoma (RCC) incidence has increased over the past two decades. (hindawi.com)
  • Renal cell carcinoma (RCC) accounts for approximately 3% of human malignancies, and its incidence appears to be increasing globally [ 1 ]. (hindawi.com)
  • Collecting duct carcinoma of the kidney (CDC) is an aggressive subtype of renal cell carcinoma with a dismal prognosis. (e-urol-sci.com)
  • Succinate dehydrogenase-deficient (SDH-deficient) renal cell carcinoma (RCC) is a rare subtype of RCC. (sajo.org.za)
  • Succinate dehydrogenase- (SDH)-deficient renal cell carcinoma (RCC) is a rare subtype of RCC, estimated to comprise 0.05% - 0.2% of all cases of RCC globally. (sajo.org.za)
  • Renal cell carcinoma (RCC) accounts for about 3% of all malignancies. (medcraveonline.com)
  • Renal cell carcinoma (RCC) is one of the most common solid neoplasm of urinary tract accounting for about 3% of all malignancies in adult. (medcraveonline.com)
  • Hypoxia is considered a critical contributor to renal cell carcinoma progression, including invasion and metastasis. (biomedcentral.com)
  • The purpose of this study was to investigate the role and mechanism of hypoxia-induced renal cell carcinoma and provide evidence-based medical proof for improvements to postoperative nursing of renal cell carcinoma patients. (biomedcentral.com)
  • A total of 64 patients with renal cell carcinoma were divided into the observation group (nursing based on oxygen administration) and the control group (conventional nursing). (biomedcentral.com)
  • The human renal cell carcinoma cell line A498 under hypoxia/normoxia was used as an experimental model in vitro and the biological characteristics and mitochondrial function of the cells were assessed. (biomedcentral.com)
  • Nursing based on oxygen administration decreased the value of renal function indexes, serum inflammatory factors, and tumor markers in renal cell carcinoma patients. (biomedcentral.com)
  • These data reveal that nursing based on oxygen administration can improve the clinical efficacy of renal cell carcinoma therapies, being safe and effective. (biomedcentral.com)
  • The results elucidate a mechanism wherein the solute carrier family 14 member 1 gene participates in the occurrence and development of hypoxia-induced renal cell carcinoma in a mitochondria-dependent manner. (biomedcentral.com)
  • Renal cell carcinoma (RCC) originates from either the cancerous renal cortex or renal tubular epithelial cells, and is the second most lethal urological malignancy, accounting for 90-95% of kidney neoplasms. (biomedcentral.com)
  • Therefore, we aimed to compare the differential expressions of PD-1, PD-L1 and PD-L2 between the primary and metastatic sites of renal cell carcinoma (RCC). (biomedcentral.com)
  • Renal cell carcinoma (RCC) is originated from the epithelium of renal tubules. (biomedcentral.com)
  • The role of genotyping and ancillary tools, in particular immunohistochemistry, in correctly classifying these tumors is highlighted in the section on Renal Cell Carcinoma. (abdominalkey.com)
  • In 2007, a 58-year-old white male with no history of tobacco use, hypertension, diabetes, or hypercholesterolemia, and no family history of coronary artery disease, was found to have a large solid right renal mass and associated tumor thrombus of the inferior vena cava and right atrium. (biomedcentral.com)
  • He underwent right radical nephrectomy and tumor thrombectomy performed under extracorporeal circulation. (biomedcentral.com)
  • Wilms tumor, treatment for which includes surgery (radical or partial nephrectomy), is the fifth most common pediatric malignancy and the most common type of renal tumor in children. (medscape.com)
  • Wilms tumor is rare in adults, accounting for only 0.5% of renal lesions. (medscape.com)
  • Gross nephrectomy specimen shows a Wilms tumor pushing the normal renal parenchyma to the side. (medscape.com)
  • Wilms tumor arises from the primitive embryonal renal tissue. (medscape.com)
  • Grossly, Wilms tumor is typically an intrarenal solid or cystic mass, which may displace and, in rare cases, invade the renal collecting system. (medscape.com)
  • The tumor extends into the renal vein in 40% of cases. (medscape.com)
  • According to the NWTSG protocol, the first step in the treatment of Wilms tumor is surgical staging followed by radical nephrectomy, if possible. (medscape.com)
  • Although end-stage kidney disease after unilateral radical nephrectomy is uncommon (0.25% in the NWTSG trial), preserving healthy kidney tissue may prevent this complication, especially in patients with an underlying intrinsic kidney disease (eg, WAGR [Wilms tumor, aniridia, genitourinary anomalies, and mental retardation] syndrome, Denys-Drash syndrome). (medscape.com)
  • RCC may not be diagnosed until after it has metastasized because the primary tumor can grow fairly large without creating symptoms such as flank pain or a mass in the abdomen. (urotoday.com)
  • The patient inside our survey Gemcitabine HCl novel inhibtior acquired renal malakoplakia but underwent a nephrectomy using the scientific medical diagnosis of a renal tumor. (buyresearchchemicalss.net)
  • The scientific impression was a renal tumor or xanthogranulomatous pyelonephritis. (buyresearchchemicalss.net)
  • Indications for nephrectomy were dominated by renal tumor (33.82%) followed by lithiasis (16.17%) and non-functioning kidney (16.17%) at the same rank. (springeropen.com)
  • 7, 8] A complete surgical procedure can be performed by laparoscopy when the tumor is small, allowing a first approach to the renal vessels without mobilization of the kidney. (medscape.com)
  • and cell differentiation ( SOX2 and TGFB3 ) as well as immunohistochemical assay for VEGFA, TP53, Bcl2, TGFB1, and Ki67 protein expression have been performed in 85 FFPE RCC tumor specimens. (hindawi.com)
  • This study presents the largest, single-institutional experience to date for managing these tumors and can, therefore, be added to the existing literature on this rare tumor. (e-urol-sci.com)
  • Renal function indexes, serum inflammatory factors, and tumor markers were evaluated. (biomedcentral.com)
  • A three-year old child presents with a large renal mass suspected to be a Wilms tumor. (pedsurglibrary.com)
  • Surgical resection is performed and pathologic evaluation shows completely resected Wilms tumor with focal penetration of the renal capsule. (pedsurglibrary.com)
  • b) blood vessels within the specimen outside of the parenchyma contain tumor. (pedsurglibrary.com)
  • Bilateral renal involvement by tumor is present at diagnosis. (pedsurglibrary.com)
  • Children with which of the following conditions should receive screening renal ultrasounds for nephroblastoma (Wilms tumor)? (pedsurglibrary.com)
  • More than 80% of renal tumors of childhood are Wilms tumor (nephroblastoma) ( 1 , 2 ). (abdominalkey.com)
  • The tumor is usually circumscribed by a pseudocapsule formed of compressed renal and perirenal tissues. (abdominalkey.com)
  • The aim of this study was to analyze the feasibility and the safety of laparoscopic nephrectomy in the treatment of pathologies of the upper urinary tract through the experience of the Urology B department. (springeropen.com)
  • We have retrospectively and monocentrally selected patients who underwent laparoscopic nephrectomy from January 2017 to December 2019. (springeropen.com)
  • Laparoscopic nephrectomy appears to be an efficient and reliable technique. (springeropen.com)
  • When it comes to urology, it all started when Ralph Clayman performed the first laparoscopic nephrectomy in 1991 [ 1 ]. (springeropen.com)
  • In 1993, Gaur proposed the retro-peritoneal (RP) approach to perform laparoscopic nephrectomy [ 4 ]. (springeropen.com)
  • Since then, laparoscopic nephrectomy has undergone significant development, whether performed trans or retroperitoneally, with or without robot assistance. (springeropen.com)
  • The aim of this study is to evaluate the feasibility of laparoscopic nephrectomy, its advantages and especially its complications through the experience of the urology B department of the Ibn Sina hospital. (springeropen.com)
  • 1993) Laparoscopic nephrectomy for renal neoplasms. (medscape.org)
  • During December 2008, in a setting of stable disease, he underwent hepatic resection and enucleation of the left renal mass. (biomedcentral.com)
  • PATIENTS AND METHODS: We included 289 patients from seven hospitals who underwent radical nephroureterectomy (RNU) for locally advanced UTUC (≥cT3 or cN+) between 2000 and 2020. (bvsalud.org)
  • He underwent a still left radical nephrectomy. (buyresearchchemicalss.net)
  • A retrospective analysis was conducted of all patients who underwent nephrectomy over a period of 30 years (1987-2016) in a large tertiary medical center. (ima.org.il)
  • A total of 1674 patients underwent nephrectomy during the study period. (ima.org.il)
  • Of those, 553 (33%) and 294 patients (17.5%) underwent left nephrectomy and radical left nephrectomy, respectively. (ima.org.il)
  • A retrospective review of the hospital's electronic database was conducted to identify the cases of CDC of the kidney from among those patients who underwent either radical or partial nephrectomy between June 2005 and January 2020. (e-urol-sci.com)
  • He was prepared for nephron-sparing surgery, with the possibility of radical nephrectomy depending on the intraoperative finding. (urotoday.com)
  • Radical nephrectomy and nephron-sparing surgery are still the only effective treatments for localized RCC, but the characteristics of RCC recurrence and metastasis lead to a 5-year survival rate of approximately 12%, posing a great challenge to clinical therapies [ 4 ]. (biomedcentral.com)
  • In patients with bilateral Wilms tumors, solitary kidney, or kidney insufficiency, partial nephrectomy is a reasonable consideration. (medscape.com)
  • During the study period, 31 (45.6%) simple nephrectomy, 26 (38.2%) total nephrectomy, 1 (1.5%) partial nephrectomy and 10 (14.7%) nephroureterectomy were performed in our department. (springeropen.com)
  • The role of partial nephrectomy remains controversial. (medscape.com)
  • Partial nephrectomy may be feasible in only 10%-15% of patients, as most tumors are too large at initial diagnosis. (medscape.com)
  • The NWTS-4 study showed an 8% local recurrence rate following partial nephrectomy for patients with bilateral disease. (medscape.com)
  • 3] In the presence of bilateral Wilms tumors, solitary kidney, or renal insufficiency, partial nephrectomy is a reasonable consideration. (medscape.com)
  • 2004) Safety and efficacy of partial nephrectomy for all T1 tumors based on an international multicenter experience. (medscape.org)
  • 2003) Comparative analysis of laparoscopic versus open partial nephrectomy for renal tumors in 200 patients. (medscape.org)
  • 2004) Laparoscopic partial nephrectomy: evaluation of long-term oncological outcome. (medscape.org)
  • Lane BR and Gill IS (2007) 5-Year outcomes of laparoscopic partial nephrectomy. (medscape.org)
  • 2007) Comparison of 1,800 laparoscopic and open partial nephrectomies for single renal tumors. (medscape.org)
  • 2002) Does the size of the surgical margin in partial nephrectomy for renal cell cancer really matter? (medscape.org)
  • 2005) Exploring the learning curve, pathological outcomes and perioperative morbidity of laparoscopic partial nephrectomy performed for renal mass. (medscape.org)
  • 1995) Partial nephrectomy: technique, complications and pathological findings. (medscape.org)
  • Herr HW (1999) Partial nephrectomy for unilateral renal carcinoma and a normal contralateral kidney: 10-year followup. (medscape.org)
  • All the cases of CDC which were diagnosed at our center following a radical or partial nephrectomy in the past 15 years were included. (e-urol-sci.com)
  • All the patients fulfilling the inclusion criteria were subjected to partial or radical nephrectomy and the specimen were sent for histopathological examination. (medcraveonline.com)
  • Dr. Anderson has clinical expertise in robotic prostatectomy for the treatment of prostate cancer, radical cystectomy with orthotopic neobladder for patients with bladder cancer, and partial nephrectomy for the treatment of kidney tumors. (columbia.edu)
  • Gross inspection of the lesion discloses gentle tan-yellow homogenous plaques and confluent nodules that are often significantly less than 1cm in size but can range up to 3 to 4cm and replace huge regions of renal Gemcitabine HCl novel inhibtior parenchyma. (buyresearchchemicalss.net)
  • Radiotherapy to the prostate bed is used to eradicate residual microscopic disease following radical prostatectomy for prostate cancer. (ima.org.il)
  • To investigate the genomic features of tertiary pattern 5 (TP5) on radical prostatectomy specimens in an effort to explain the poor clinical outcomes associated with this disease subtype. (bjuinternational.com)
  • Among those, four patients (0.2% of the total group, 0.7% of the left nephrectomy group, and 1.36% of the radical left nephrectomy) experienced iatrogenic injuries to the pancreas. (ima.org.il)
  • 1 Although majority of the patients present with localised disease, approximately 30% of patients are diagnosed with metastasis 2 and another 30% of patients develop metastasis after radical nephrectomy. (medcraveonline.com)
  • Collecting duct carcinoma (CDC) of the kidney is a rare and aggressive subtype of renal cancer arising from the collecting duct epithelium of the kidney with an incidence of 0.4%-1.8% of all renal tumors. (e-urol-sci.com)
  • Clear cell RCC was not diagnosed until histological evaluation was completed after a nephrectomy. (urotoday.com)
  • although it is derived from cells of the renal tubular epithelium, it has several histological subtypes which differ in their clinical outcome and biological features. (hindawi.com)
  • Ours is a landmark study correlating inflammatory markers with various renal tumour histological characteristics. (medcraveonline.com)
  • There are three main histological subtypes of RCC, including clear cell RCC (ccRCC), papillary RCC, and chromophobe RCC, which jointly represent over 85% of all primary renal malignancies [ 3 ]. (biomedcentral.com)
  • If imaging studies demonstrate bilateral disease, nephrectomy is not performed, but biopsy specimens are obtained. (medscape.com)
  • CDC's presentation is nonspecific and similar to other renal malignancies. (e-urol-sci.com)
  • Large tumors that extend beyond the midline, have vascular extension, or both are relative contraindications, since some surgeons elect to obtain tissue via surgical excision, but this may expose patients to increased surgical risks. (medscape.com)
  • Conclusion Renal malakoplakia must be kept in mind for patients presenting with a renal mass and a history of long-term recurrent renal infections or renal failure. (buyresearchchemicalss.net)
  • The medical diagnosis of malakoplakia should be considered for patients delivering using a renal mass and NOTCH1 a brief history of long-term repeated renal attacks or renal failing [4]. (buyresearchchemicalss.net)
  • All of these patients were treated initially and had at least one measurable focus according to standard Response Evaluation Criteria in Solid Tumors (RECIST) [15]. (cyp17-signal.com)
  • Seven patients (5%) were operated by resection and 145 (95%) by radical nephrectomy. (cyp17-signal.com)
  • A few months later, hepatic and contralateral renal metastases were detected. (biomedcentral.com)
  • The treatment for renal parenchymal tumors has changed over time, and this trend continues today as a result of technological progress made with clinical research and improved diagnostic and therapeutic tools. (biomedcentral.com)
  • Pancreatic injuries during nephrectomy are rare and carry a significant risk for postoperative morbidity. (ima.org.il)
  • Effectiveness of perioperative chemotherapy and radical cystectomy in treating bladder cancer. (moffitt.org)
  • Pathological examination of the surgical specimens demonstrated pT3cN0Mx conventional (clear cell) renal carcinoma, Fuhrman Grade 3 with negative surgical margins. (biomedcentral.com)
  • Dr. Spiess' research interests include novel therapies for advanced renal, bladder and penile cancer. (moffitt.org)
  • Recently, the markers of inflammation like C-reactive protein (CRP), neutrophil lymphocyte ratio (NLR) and Serum lactate dehydrogenase (LDH) are being extensively studied in solid tumours and in most of the studies it has been established that markers of inflammation bears a prognostic information in most of the carcinoma including RCC. (medcraveonline.com)
  • Pancreatic injuries during nephrectomy are rare, despite the relatively close anatomic relation between the kidneys and the pancreas. (ima.org.il)
  • surgical removal created_by: mshimoyama creation_date: 2011-11-02T02:06:00Z [Term] id: XCO:0000018 name: bilateral nephrectomy def: "Surgical removal of both kidneys. (mcw.edu)
  • In addition, preliminary but encouraging data indicate that a laparoscopic approach to nephrectomy in benign disease is associated with decreased lengths of hospital stay and analgesic requirements in the pediatric patient. (medscape.com)
  • With this background in mind, we carried out a prospective study to find out any association between the inflammatory markers and renal tumour characteristics like histology, tumour size, presence of necrosis and calcification. (medcraveonline.com)
  • Whether these markers of systemic inflammation play any role in the incitation of these renal tumours as observed in our study is yet to be known. (medcraveonline.com)
  • Coyne T, Olson M, Bradham K, Garcon M, Gregory P, Scherch L: Dietary satisfaction correlated with adherence in the Modification of Diet in Renal Disease Study [url=https://collegegate.org/lab/purchase-cheap-caverta/] erectile dysfunction mayo clinic best purchase caverta[/url]. (ehd.org)
  • Early radiological assessment after surgery showed no residual hepatic or renal disease, but possible involvement of the mesenteric lymph nodes. (biomedcentral.com)
  • To assess the frequency and the clinical significance of pancreatic injuries during nephrectomy. (ima.org.il)
  • The classification of epithelial tumors of the kidney has in particular undergone substantial progress in the last two decades with major contributions from genetic typing of renal cell carcinomas (RCCs). (abdominalkey.com)
  • Further investigation of a larger patient population is needed to better understand cardiac damage due to TKI treatment. (biomedcentral.com)