Specificity antibody chlamydia trachomatis. Medical search. Frequent questions

Chlamydia trachomatis causes a high number of sexu- persons unaware of their infection status facilitates further ally transmitted infections worldwide, but reproducible and transmission. (cdc.gov)
citation needed] Clinical signs and symptoms of C. trachomatis infection in the genitalia present as the chlamydia infection, which may be asymptomatic or may resemble a gonorrhea infection. (wikipedia.org)
C. trachomatis in the lungs presents as the chlamydia pneumoniae respiratory infection and can affect all ages. (wikipedia.org)
CIO Responsible for this publication: National Center for Prevention Services, Division of Sexually Transmitted Diseases and HIV Prevention Chlamydial Infections Among Children Sexual abuse must be considered a cause of chlamydial infection among preadolescent children, although perinatally transmitted C. trachomatis infection of the nasopharynx, urogenital tract, and rectum may persist beyond 1 year (see Sexual Assault or Abuse of Children). (cdc.gov)
Chlamydia psittaci infection among humans (psittacosis) and pet birds (avian chlamydiosis), also known as parrot disease, parrot fever, and ornithosis, is a zoonotic bacterial disease. (health.mil)
A properly obtained negative C trachomatis culture indicates the absence of infection with 100% specificity. (medscape.com)
Trachoma, caused by ocular Chlamydia trachomatis infection, is targeted for global elimination as a public health problem by 2030. (cdc.gov)
For many pathogens, serum antibodies can be detected long after resolution of infection, but infection status is often used as a gold standard for antibody positivity. (cdc.gov)
The endocervix, the primary site of Chlamydia trachomatis (Ct) infection in women, has a unique repertoire of locally synthesized IgG and secretory IgA (SIgA) with contributions from serum IgG. (lsuhsc.edu)
Taken together, these data suggest that (i) genital IgA most effectively inhibits Ct infection in vitro, (ii) human antibody-mediated inhibition of Ct infection is significantly influenced by the ompA genotype of the infecting strain, (iii) the genital antibody repertoire develops or matures differently compared to systemic antibody, and (iv) ompA genotype-specificity of inhibition of infection by whole serum can be overcome by high concentrations of Ct-specific IgG. (lsuhsc.edu)
and Quayle, Alison J., "Human Genital Antibody-Mediated Inhibition of Chlamydia Trachomatis Infection and Evidence for ompA Genotype-Specific Neutralization" (2021). (lsuhsc.edu)
We conclude that the currently used IPA method for chlamydia diagnosis overestimates C. trachomatis infection and its specificity for the diagnosis of C. trachomatis is limited. (karger.com)
Screening programs have been demonstrated to reduce both the prevalence of C. trachomatis infection and rates of PID in women (79,80). (cdc.gov)
However, following Pap screening, there should be a clinical indication for reflex additional testing of liquid cytology specimens for chlamydia and gonorrhea since these specimen types are more widely used in older populations at low risk for infection. (cdc.gov)
When a pregnant woman has a C trachomatis infection of the cervix, the organism is transmitted when the infant passes through the infected birth canal. (medscape.com)
The Chlamydia Rapid Test is a meaningful test for point-of-care diagnosis of a chlamydia infection. (rapidtest.com)
The available differentiating tests for Chlamydia are based on detection of genetic material and only give information about the actual infection status, but reveal nothing of past infections. (biomedcentral.com)
In birds, C. psittaci infections can result in mild to severe disease, depending on the avian species and the Chlamydia strain, whereas an infection in humans can lead to severe pneumonia, i.e. psittacosis [ 7 ]. (biomedcentral.com)
Chlamydia trachomatis (CT) infection in pregnancy can cause maternal disease, adverse pregnancy outcomes, and neonatal disease [ 1-6 ]. (jocmr.org)
Prior infection with chlamydia is more frequent in C. glucuronolyticum -positive patients with urethritis. (em-consulte.com)
In the urethritis group, the species was more frequently found as a sole isolate ( p = 0.041) and after prior infection with Chlamydia trachomatis ( p = 0.025). (em-consulte.com)
Chlamydia, or more specifically a chlamydia infection, is a sexually transmitted infection caused by the bacterium Chlamydia trachomatis. (anhourago.eu)
The presence or absence of type-specific antibodies can help to differentiate between primary and non-primary infection. (canada.ca)

FDA- approved Chemiluminescent Acridinium Ester technology provides superior sensitivity and specificity to detect antibodies to sexually transmitted viral infections. (usbiotek.com)
[ 1 , 2 ] Nucleic acid amplification test (NAAT) has surpassed this as the criterion standard, with sensitivity ranging from 85-95% with 99-100% specificity. (medscape.com)
Although C trachomatis culture has a lower sensitivity compared to NAATs, maintaining the ability to perform this laboratory test is still important. (medscape.com)
Self-collected vaginal swabs are equivalent in sensitivity and specificity to those collected by a clinician (83,88). (cdc.gov)
It is characterized by high sensitivity and specificity and allows you to get results in a relatively short time. (lab24.pl)
Relative sensitivity and relative specificity are compared to RT-PCR. (roche.com)
WHO expects that an IVD performs as it is intended to (e.g. sensitivity and specificity, precision, trueness of measurement, etc.) when used by operators in WHO Member States. (who.int)
NAAT approaches sensitivity and specificity of 100%, with rapid turn-around of results Footnote 1 Footnote 22 Footnote 23 . (canada.ca)
A study of TSS showed a sensitivity of 80.5% and specificity of 98.5% for HSV-2, and a sensitivity of 91% and specificity of 96.4% for HSV-1 Footnote 28 . (canada.ca)
The coronavirus antigen check out tools's sensitivity and specificity are in distinction in the direction of a CE-IVD marked RT-PCR check out tools. (biocortech.com)

C. trachomatis along with C. pneumoniae have been found to infect humans to a greater extent. (wikipedia.org)
Genus specific (C. trachomatis, C. pneumoniae & C. psittaci). (idhinhibitor.com)
The SPEIA test identified 41 (33.6%) of those as positive for C. trachomatis and 81 (66.4%) positive for C. pneumoniae . (karger.com)
By using the SPEIA test, it is possible to distinguish between C. trachomatis and C. pneumoniae seropositivity. (karger.com)
The sequential incubation of anti-GLXA antibody and complement with Chlamydia trachomatis serovar K or C. pneumoniae AR-39-infected HeLa 229 or macrophage cells resulted in significant cellular cytotoxicity, which preceded the formation of mature elementary bodies. (umass.edu)
For uninfected cells, co-incubation of GLXA, purified from supernatants of either C. trachomatis or C. pneumoniae-infected HeLa 229 cells, followed by the successive addition of mouse anti-GLXA antibody and complement, yielded similar levels of cellular cytotoxicity. (umass.edu)
Chlamydophila pneumoniae , Chlamydophila psittaci , and Chlamydia trachomatis . (medscape.com)
The mode of transmission is different among the three species ( C pneumoniae , C psittaci , and C trachomatis ), but all can cause systemic disease by hematogenous spread. (medscape.com)

This test is an in vitro nucleic acid amplification test for the qualitative detection of Chlamydia trachomatis (CT) and/or Neisseria gonorrhoeae (NG) in patient specimens. (roche.com)
The organisms Chlamydia trachomatis and Neisseria gonorrhoeae are generally accepted pathogens in urethritis and cervicitis. (bmj.com)

The cultures should be confirmed by microscopic identification of the characteristic intracytoplasmic inclusions, preferably by fluorescein-conjugated monoclonal antibodies specific for C. trachomatis. (cdc.gov)
In the test procedure, a unique set of polyclonal and monoclonal antibodies are employed. (rapidtest.com)
The identification is based on the monoclonal antibodies specific for the novel coronvirus antigen. (oegterm.at)

Chlamydia psittaci is a bacterium that can be transmitted from pet birds to humans. (cdc.gov)
The civilian hospital collected a serum specimen on 5 March 2018 for a C. psittaci microimmunofluorescence (MIF) immunoglobulin M (IgM) antibody test. (health.mil)
The suspension array correctly identified antibodies against various Chlamydia species in sera from experimentally infected mice, and was also able to differentiate between antibodies against C. psittaci and C. gallinacea in sera from experimentally infected chickens. (biomedcentral.com)
The goal of this study is to investigate if it is possible to develop a serological test that, in chicken serum, can differentiate between antibodies against different Chlamydia species, particularly C. psittaci and C. gallinacea , using peptides as antigens. (biomedcentral.com)

C erence strains and 68 geographically diverse clinical iso- hlamydia trachomatis , a bacterium that can infect both lates, identified 44 MLST sequence types (STs), compared men and women, is most commonly sexually trans- with only 20 ompA genotypes ( 11 ). (cdc.gov)
C. trachomatis is the most common infectious cause of blindness and the most common sexually transmitted bacterium. (wikipedia.org)
Chlamydia trachomatis is a gram-negative bacterium that can replicate only within a host cell. (wikipedia.org)

Chlamydia Antibody Laboratories manufactures the chlamydia trachomatis igg antibody reagents distributed by Genprice. (cdna-clone.com)
Human Antibody Laboratories manufactures the names of specialty perscription human anti bodies reagents distributed by Genprice. (sebov-detection.com)
Human IgG antibody Laboratories manufactures the sars-co2 antibody test reagents distributed by Genprice. (gfpvector.com)
Human IgG antibody Laboratories manufactures the pcr tail direct reagents distributed by Genprice. (prionics.com)

C. trachomatis is the single most important infectious agent associated with blindness (trachoma), and it also affects the eyes in the form of inclusion conjunctivitis and is responsible for about 19% of adult cases of conjunctivitis. (wikipedia.org)
If transmitted to infants during birth, Chlamydia can cause conjunctivitis and pneumonia. (rapidtest.com)
Trachoma is a chronic conjunctivitis caused by Chlamydia trachomatis. (anhourago.eu)

trachomatis infections are the leading cause of sexually transmitted diseases in the United States. (ammoliteprodukties.nl)
Chlamydia trachomatis are obligate intracellular bacterial pathogens that cause ocular and genital infections, which are a significant public health concern worldwide. (europa.eu)
A better understanding of C. trachomatis basic biology is important to eventually develop new ways to combat infections caused by these bacteria. (europa.eu)
For patient education information, see the Infections Center and the Sexual Health Center , as well as and Bacterial Pneumonia and Chlamydia . (medscape.com)
Chlamydia is one of the most common sexually transmitted infections, affecting about 4.2% of women and 2.7% of men worldwide. (anhourago.eu)
To study the prevalence, symptoms and signs of Mycoplasma genitalium and Chlamydia trachomatis infections in STD clinic attendees and in partners of M genitalium infected patients. (bmj.com)
From September 1995 through October 1997, samples for M genitalium, C trachomatis, and N gonorrhoeae were collected from 946 consecutive patients attending because of symptoms of sexually transmitted infections or for a check up. (bmj.com)

C. trachomatis are bacteria in the genus Chlamydia, a group of obligate intracellular parasites of eukaryotic cells. (wikipedia.org)
Chlamydia trachomatis is a gram-negative, obligate intracellular parasite that is linked to several diseases. (medscape.com)
Chlamydia trachomatis is a small gram-negative, obligate intracellular parasite that is deficient in energy metabolism. (medscape.com)

Objectives To report sex and age-specific Chlamydia trachomatis (Ct) seroprevalence estimates in the general population of the Netherlands between 1996 and 2017 and identify risk factors associated with Ct seropositivity. (bmj.com)
Using a multiplex bead assay to measure antibodies to the C. trachomatis antigen Pgp3, seroprevalence in 1-9-year-olds was 30.2% in Kiritimati and 31.4% in Tarawa. (cdc.gov)

Thus, antibodies act as a defense against potentially harmful foreign organisms and their products. (technologynetworks.com)

We have raised rabbit polyclonal antibodies against 5 of these proteins and we are currently analysing their subcellular localisation in C. trachomatis infected cells. (europa.eu)
Description: Chicken polyclonal antibody recognizing the SARS-CoV Papain-like Protease (PLpro) as a 35 kDa protein. (gfpvector.com)

Diagrammatic representation of the specificity of the antigen - antibody reaction that enables detection and localization of a single target in a milieu of thousands of intracellular molecules. (technologynetworks.com)
Applications Reported: The eBio17B7 antibody has been reported useful for intracellular staining for flow cytometric analysis. (thermofisher.com)
Applications Tested: This eBio17B7 antibody has been tested by intracellular staining and flow cytometric analysis of restimulated, Th17-polarized mouse splenocytes using the Intracellular Fixation and Permeabilization Buffer Set (cat. (thermofisher.com)

CusabioCUP1-1 Antibody is Available at Gentaur Genprice with the fastest delivery.Online Order Payment is possible or send quotation to [email protected]. (joplink.net)
CusabioCUP1-1 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.Online Order Payment is possible or send. (joplink.net)

Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. (crossfirebeilstein.com)

Because of the potential for a criminal investigation and legal proceedings for sexual abuse, diagnosis of C. trachomatis among preadolescent children requires the high specificity provided by isolation in cell culture. (cdc.gov)
When diagnosis of C trachomatis is disputed, a culture should be performed. (medscape.com)

Seroepidemiology, or measuring antibodies to pathogens to estimate population-level exposure, can provide useful public health data. (cdc.gov)
Chlamydia trachomatis is one of the most common sexually transmitted pathogens. (rapidtest.com)

Although chlamydia prevalence data have provided a basis for setting age guidelines for routine annual screening and behavioral guidelines for targeted screening in women (11), no such consensus has been reached regarding control program definitions in men who have sex with women (12). (cdc.gov)
Table 1 shows the maternal age distribution under the three CT screening tests (CT nucleic acid detection tests with and without PCR and CT antibody detection tests). (jocmr.org)
Table 2 shows the results of CT screening tests (CT nucleic acid detection tests with and without PCR and CT antibody detection tests) of the study population by age. (jocmr.org)

M genitalium and C trachomatis were detected by polymerase chain reaction from urethral and endocervical swab specimens in a cross sectional study among 445 female and 501 male STD clinic attendees. (bmj.com)

If Chlamydia trachomatis antigen is present, the labeled antibody dye conjugate bind to it, forming an antibody antigen complex. (rapidtest.com)

Human Genital Antibody-Mediated Inhibition of Chlamydia Trachomatis In" by Caleb M. Ardizzone, Hannah L. Albritton et al. (lsuhsc.edu)
At equivalent low concentrations of Ct EB (D/UW-3/Cx + E/UW-5/Cx)-specific antibody, genital-derived IgG and IgA and serum IgA, but not serum IgG, significantly inhibited inclusion formation, with genital IgA being most effective, followed by genital IgG, then serum IgA. (lsuhsc.edu)

Vaginal swab specimens are as sensitive as cervical swab specimens, and there is no difference in specificity (82-87). (cdc.gov)
Diagnostic Automation offers a OneStep Chlamydia RapiCard InstaTest is a rapid immunoassay for direct qualitative detection of Chlamydia trachomatis antigen endocervical or endourethral swab specimens. (rapidtest.com)

Serum antibodies were analysed using Medac Ct IgG ELISA test. (bmj.com)
The Chlamydia Trachomatis Igg Antibody reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (cdna-clone.com)
Description: A sandwich ELISA for quantitative measurement of Rat anti Chlamydia trachomatis,CT antibody IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. (cdna-clone.com)
Description: Qualitative indirect ELISA kit for measuring Human anti-Chlamydia trachomatis (CT) antibody (IgG) in samples from serum. (cdna-clone.com)
Description: Qualitativeindirect ELISA kit for measuring Mouse Chlamydia trachomatis (CT) antibody (IgG) in samples from serum, plasma. (cdna-clone.com)

C. trachomatis exclusively infects humans. (wikipedia.org)
7] Chlamydia trachomatis only occurs in humans. (anhourago.eu)

Two clones were selected to evaluate the test performance of three assays to measure antibodies to Pgp3: multiplex bead assay (MBA), enzyme-linked immunosorbent assay (ELISA), and lateral flow assay (LFA). (cdc.gov)

Antibody responses in young children provide a robust, generalizable approach to monitor population progress toward and beyond trachoma elimination. (cdc.gov)
To ensure that recently developed antibody tests for seroepidemiology of Chlamydia trachomatis (Ct), the causative agent of urogenital chlamydia and the blinding eye disease trachoma, have high performance, we generated a chimeric antibody to the immunodominant Ct antigen Pgp3. (cdc.gov)
C trachomatis is an important cause of sexually transmitted diseases, including trachoma , pelvic inflammatory disease , and cervicitis . (medscape.com)

Other Chlamydia products are available in stock. (cdna-clone.com)

Cell surface display of the chlamydial glycolipid exoantigen (GLXA) demonstrated by antibody-dependent complement-mediated cytotoxicity. (umass.edu)
To study the function of known effectors, we focused on the C. trachomatis Inc proteins, an important group of potential chlamydial virulence factors. (europa.eu)

12] Chlamydia is also a potential cause of prostatic inflammation in men, although the exact relevance in prostatitis is difficult to ascertain due to possible contamination from urethritis. (anhourago.eu)
M genitalium and C trachomatis were not associated with symptoms of urethritis or cervicitis in women. (bmj.com)

IHC, in combination with microscopy and image analysis techniques, has become a very powerful tool that offers a direct visualization of tissue antigens using labeled antibodies specific to the antigen. (technologynetworks.com)
While the development of this important technique could not have been possible without the discovery of antibodies by Emil von Behring and Shibasabura Kitasato in 1890, 1 it wasn't until 1923 that the antigen - antibody complex was detected by Michael Heidelberger using labeled antigens. (technologynetworks.com)
3 , 4 The labeling of antibodies with the fluorescent tag, fluorescein, and the detection of their respective antigens in cells and tissues was pioneered by Albert Hewett Coons and others in 1941 5 and kickstarted the immunostaining revolution. (technologynetworks.com)
To enable differentiating serology, a bead-based Luminex suspension array was constructed, using peptides as antigens, derived from known immunoreactive Chlamydia proteins. (biomedcentral.com)
When loaded with immune complexes (IC), consisting of tumor antigens bound to antitumor antibody, BMDC induce powerful antitumor immunity in mice. (stanford.edu)

Positive Serology for Chlamydia: Is It Always for Chlamydia trachomatis? (karger.com)
Interpretation of EBV serology for human body material donors : is there a need for early antigen IgG and heterophile antibodies testing? (ugent.be)

Diagnostic Considerations - Nonculture chlamydia tests should not be used because of the possibility of false-positive test results. (cdc.gov)
STD's: Tests for both chlamydia and gonorrhea are accurate if done by CDC standards, but if one develops a discharge or odor , retesting is advised. (ammoliteprodukties.nl)
However, CT antibody detection by IgA tests has been substituted for these methods by some of obstetricians. (jocmr.org)
Of the 1,644 obstetrical facilities, CT nucleic acid detection PCR tests, CT nucleic acid detection tests except PCR and CT antibody detection tests were performed in 1,221 (74.3%), 408 (24.8%) and 15 (0.9%) facilities, respectively. (jocmr.org)

183194 − Chlamydia / Gonococcus, Nucleic Acid Amplification. (ammoliteprodukties.nl)

Application Instructions These antibodies have been qualified for use in ELISA to detect Chlamydia trachomatis elementary bodies and reticulate bodies. (qedbio.com)
These include the use of NAATs to detect chlamydia. (medscape.com)

Then, we selected 48 genes that may encode uncharacterised effectors (e. g. no detectable amino acid identity to other proteins or with a particular putative biochemical activity) from the genome of C. trachomatis strain L2/434/Bu. (europa.eu)

C. trachomatis and N. gonorrhoeae control efforts in men differ substantially from those recommended for women. (cdc.gov)

In addition to the chromosome that contains most of the genome, nearly all C. trachomatis strains carry a 7.5 kilobase plasmid that contains 8 genes. (wikipedia.org)

Description: SARS-CoV Spike antibody: A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). (gfpvector.com)

Description: The eBio17B7 antibody reacts with mouse and rat IL-17A with no recognition of IL-17F. (thermofisher.com)

Chlamydia Test: Types, Purpose, Procedure & Results Skip to main contented. (ammoliteprodukties.nl)

To provide evidence for use of antibodies to monitor C. trachomatis transmission, we collated IgG responses to Pgp3 antigen, PCR positivity, and clinical observations from 19,811 children aged 1-9 years in 14 populations. (cdc.gov)
Although there are no recommendations to screen heterosexual men, it USPSTF suggests testing to test sexually active heterosexual men in clinical settings with a high prevalence of C. trachomatis (e.g. (cdc.gov)
Determination of viral load on automated equipment allows analysis of all 6 (1-6) genotypes of HCV, has high clinical specificity of the test (100%) and almost completely excludes possible diagnostic errors at all stages of analysis. (lab24.pl)

It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. (thermofisher.com)

Immunohistochemistry (IHC) is an important evaluation tool that falls under the umbrella of immunostaining techniques and exploits antigen - antibody binding to study the status of target molecules in tissues of interest. (technologynetworks.com)
Antibodies are small protein molecules that are naturally expressed by the immune system of the body in response to the entry of a foreign molecule (antigen) and help in neutralizing it. (technologynetworks.com)
The beauty of the antigen - antibody reaction is that each antibody is specific to only a portion of the antigen, called an epitope, and does not bind other molecules that do not match its target, including the body's own molecules. (technologynetworks.com)
Immunostaining is an umbrella term that encompasses all the techniques that are used for the detection of molecules employing the antigen - antibody reaction. (technologynetworks.com)
Immunohistochemistry or immunohistochemical staining is a specific use case of immunostaining when the antigen - antibody reaction is used to study the status of molecules in tissue (from the Greek histos , which means tissue). (technologynetworks.com)
Apart from being an acidic medium containing an assortment of antimicrobial molecules including antibodies (IgA and IgG), mucins, β-defensins, secretory leucocyte protease inhibitor (SLPI), neutrophil gelatinase-associated lipocalin (NGAL), surfactant protein etc. (frontiersin.org)

The new Swedish variant of C trachomatis, which eluded NAATs, was detected because the organism could be cultured. (medscape.com)
The primary method for detection of Chlamydia is growth of the organism in cell culture. (rapidtest.com)
The antibodies against the molecule of interest, often a protein, are generated in an organism of a different species and are typically labeled or are aided by another set of labeled antibodies. (technologynetworks.com)

Anti-hTLR6-IgG (clone C5C8) is a monoclonal antibody specific for human Toll-like receptor 6 (hTLR6, CD286). (invivogen.com)

They share a unique hydrophobic motif thought to target them to the membrane of the large vacuole where Chlamydia resides intracellularly. (europa.eu)

Chlamydia can be spread during vaginal, anal, or oral sex, and can be passed from an infected mother to her baby during childbirth. (anhourago.eu)

Specificity: High affinity for LPS. (idhinhibitor.com)

One antibody is immobilized on a porous membrane while the other antibody is conjugated to dye particles as signaling component. (rapidtest.com)

The C. trachomatis genome is substantially smaller than that of many other bacteria at approximately 1.04 megabases, encoding approximately 900 genes. (wikipedia.org)
Several important metabolic functions are not encoded in the C. trachomatis genome, and instead, are likely scavenged from the host cell. (wikipedia.org)

Anatomy15

Organisms18

Diseases46

Chemicals and Drugs35

Analytical, Diagnostic and Therapeutic Techniques and Equipment31

Psychiatry and Psychology2

Phenomena and Processes15

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Information Science4

Named Groups2

Health Care12

Geographicals1

Infection23

Sensitivity10

Pneumoniae8

Neisseria2

Monoclonal antibodies3

Psittaci4

Bacterium3

Reagents4

Conjunctivitis3

Infections7

Obligate3

Seroprevalence2

Organisms1

Polyclonal2

Intracellular3

Genprice2

Detection of antibodies1

Diagnosis2

Pathogens2

Screening3

Polymerase Chain Re1

Antigen complex1

Genital2

Swab specimens2

Serum5

Humans2

Assays1

Trachoma3

Products are available in stock1

Chlamydial2

Urethritis2

Antigens5

Serology2

Tests4

Nucleic acid1

Detect2

Strain1

Gonorrhoeae1

Plasmid1

Coronavirus1

Reacts1

Skip1

Clinical3

Assay1

Molecules6

Organism3

Clone1

Vacuole1

Vaginal1

Affinity1

Membrane1

Genome2