• Some aspidogastreans have been recorded from few host species, but most have a low degree of host specificity, i.e., they infect a wide range of host species. (tolweb.org)
  • The atypical DUSPs share a high degree of similarity with the MKP subgroup, but lack the N-terminal regulatory domain, which provides the substrate specificity towards the MAP kinases. (ebi.ac.uk)
  • Mapping and manipulation of very large genomes, including the human genome, would be facilitated by the availability of a DNA cleavage method with very high site specificity. (sciencemag.org)
  • Furthermore, we find that different CESA isoforms vary greatly in their levels of site specificity and this is likely to be determined by the constraints imposed by their position within the CSC rather than their primary structure. (plantphysiol.org)
  • In this review, we discuss the mechanisms of SERM tissue specificity and highlight the therapeutic application of well-known and emergent SERMs. (dovepress.com)
  • Additional data are needed to assess test specificity in patients with potential cross-reacting conditions such as syphilis and connective tissue disorders. (asm.org)
  • Retrieved on November 12, 2019 from https://www.news-medical.net/news/20190619/New-ZetaView-QUATT-enhances-nanoparticle-analysis-specificity.aspx. (news-medical.net)
  • The second order neurons, mitral cells in mammals and projection neurons in insects, have a similar degree of wiring specificity: studies in Drosophila suggest that projection neuron-intrinsic mechanisms regulate their precise dendritic targeting. (nih.gov)
  • Finally, recent studies have revealed interactions of different cell types during circuit assembly, including axon-axon interactions among olfactory receptor neurons and dendro-dendritic interactions of projection neurons, that are essential in establishing wiring specificity of the olfactory circuit. (nih.gov)
  • Warning: in the medical context (diagnosis), specificity is defined differently: there it is TNeg / (FPos + TNeg). (avatar.se)
  • Statistical analysis of homologue sequences can identify putative specificity determining positions (SDPs) and help to shed some light on the peculiarities underlying their functional role. (mdpi.com)
  • Its specificity was 96% to 99% when blood culture was used as the gold standard comparator, and 98% to 100% when a composite of clinical and microbiological criteria was used. (healio.com)
  • Now, I want to check the primer specificity (i.e. can I use this primer as an identification tool to detect a specific species using PCR) and the question is: do I need to BLAST the primer sequence (both forward and reverse) or to BLAST the sequence of the amplified fragment (PCR product). (bio.net)
  • Current proponents of domain specificity argue that evolution equipped humans (and indeed most other species) with specific adaptations designed to overcome persistent problems in the environment. (wikipedia.org)
  • The data displayed in Figure 3, however, represents SONAR generated data highlighting the specificity of the technique by resolving co-eluting lipid species. (waters.com)
  • To determine which amino acids may play a role in Gpa2 and Rx1 specificity, we combined sequence information of 35 closely related homologues derived from wild Solanum species, functional data and a consensus in sillico 3D model obtained in previous studies. (wur.nl)
  • Specificity is the proportion of true negatives that are correctly identified by the test. (bmj.com)
  • Similarly for specificity, it will be given that the subject do not have the disease, this is the 983 plus 63,650 participants, and knowing that you look at people who test negative, and you make the calculation. (coursera.org)
  • Specificity (true negative fraction, TNF) measures the ability of a test to detect the absence of the condition when it is not present. (analyse-it.com)
  • How likely is the test to detect the absence of a characteristic in someone without the characteristic ( specificity )? (wikihow.com)
  • Resting conidia from a genetically marked heterokaryon of N-crassa in the resting stage and vegetative N-crassa cells were tested for mutagenicity and mutagenic specificity by the adenine-3 (ad-3) test system, using various concentrations of metronidazole and niridazole. (cdc.gov)
  • A specificity of 100% means that the test recognizes all actual negatives - for example, all healthy people will be recognized as healthy. (thefullwiki.org)
  • Because 100% specificity means no positives are erroneously tagged, a positive result in a high specificity test is used to confirm the disease. (thefullwiki.org)
  • Therefore, the specificity alone does not tell us how well the test recognizes positive cases. (thefullwiki.org)
  • A test with a high specificity has a low type I error rate. (thefullwiki.org)
  • A test with very high specificity can have very low precision if there are far more true negatives than true positives, and vice versa . (thefullwiki.org)
  • OriGene has applied the High-Density Protein Microarray to test the specificity of over 100 UltraMAB┬« and other commercial antibodies. (origene.com)
  • Several test kits can detect latent Mtb infection with better specificity than the tuberculin based skin test. (frontiersin.org)
  • The UK authorities have put forward a 99.9% specificity as an acceptable performance for a vCJD test on blood donor samples and these first results suggest we can meet or exceed this requirement. (newswire.ca)
  • Finally, the ISM was employed to analyze and verify several mutations in HA1 well known for their critical roles in binding specificity switch, including E190D/G225D in H1N1 and Q192R/ S223L/ Q226L/ G228S in H5N1. (scirp.org)
  • Specificity to Zika NS1 was demonstrated with no sensor response to Japanese Encephalitis NS1, a closely-related infection that potentially produces false positives. (prweb.com)
  • Specificity is sometimes confused with the precision or the positive predictive value , both of which refer to the fraction of returned positives that are true positives. (thefullwiki.org)
  • A mechanism of the action of the lipase explaining the specificity of its action is proposed. (springer.com)
  • ARTICLE{Davies00specificityand, author = {Stephen P. Davies and Helen Reddy and Matilde Caivano and Philip Cohen}, title = {Specificity and mechanism of action of some commonly used protein kinase inhibitors}, journal = {Biochem. (psu.edu)
  • Domain specificity is a theoretical position in cognitive science (especially modern cognitive development ) that argues that many aspects of cognition are supported by specialized , presumably evolutionarily specified, learning devices. (wikipedia.org)
  • Domain specificity emerged in the aftermath of the cognitive revolution as a theoretical alternative to empiricist theories that believed all learning can be driven by the operation of a few such general learning devices. (wikipedia.org)
  • Our findings indicate that quorum-sensing-controlled promoters in P. aeruginosa are either specific for LasR or respond to both LasR and RhlR and that critical bases in the promoter elements determine specificity. (asm.org)
  • Intensive research on the specificity and function of immunological responses is of major importance since protective host defense is critically dependent on T cells, which selectively recognize only certain antigens and epitopes of the tubercle bacillus. (frontiersin.org)
  • The specificity of the host immune response may also help to explain how the intracellular tubercle bacilli evade host resistance, probably by decoy pro-inflammatory actions of some of their antigens and/or immunomodulatory constituents, which lead to chronic infection and lung pathology. (frontiersin.org)
  • The four antigens identified by Hefty as most important in the humoral response to early Lyme disease-OspE, OspC, ElpB1, and FlaB-have specificities of 0.921, 1.00, 0.968, and 0.921, respectively (D. R. Akins, personal communication). (asm.org)
  • This paper assesses the age specificity of the infection fatality rate (IFR) for COVID-19. (nber.org)
  • the specificity value would be 122 ( 0,1,2,2 or 0122): 100 for #content, 10 for .data, 10 for :hover, 1 for body and 1 for img. (smashingmagazine.com)
  • Specificity (also called the true negative rate ) measures the proportion of negatives that are correctly identified as such (e.g. the percentage of healthy people who are correctly identified as not having the condition). (wikipedia.org)
  • Specificity measures the proportion of negatives which are correctly identified (e.g. the percentage of healthy people who are identified as not having the condition). (thefullwiki.org)
  • Specificity is the fraction of the sequences predicted as matches that really are true matches. (avatar.se)