• In vitro selection and extended culture of antigen-specific T lymphocytes. (rupress.org)
  • Induction of antigen-specific immune tolerance, which reduces autoreactive immune cells and generates antigen-specific regulatory T cells in patients, is a promising strategy for curing autoimmune diseases. (drexel.edu)
  • Systemic administration of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with auto-antigen peptides have been demonstrated to induce antigen-specific immune tolerance in experimental autoimmune encephalitis (EAE), a murine model of multiple sclerosis. (drexel.edu)
  • After reducing the complement activation of nanoparticles, we show that nanoparticles encapsulating MOG peptide can induce antigen-specific immune tolerance in EAE after disease onset via s.c. administration of the nanomaterials. (drexel.edu)
  • Dr. Cheng's laboratory focuses on cell membrane-derived hydrogels, long circulating nanoparticles, and biomaterials/biological materials for inducing antigen-specific immune tolerance. (drexel.edu)
  • I. Description of selection culture procedure and initial characterization of selected cells. (rupress.org)
  • Cloning and initial characterization of human epsin 3, a novel matrix-induced keratinocyte specific transcript. (nih.gov)
  • OTCQX: RHHBY) announced that the US Food and Drug Administration (FDA) has accepted the company's supplemental Biologics License Application (sBLA) and granted Priority Review for TECENTRIQ® (atezolizumab), in combination with Avastin® (bevacizumab), paclitaxel and carboplatin (chemotherapy), for the initial (first-line) treatment of people with metastatic non-squamous non-small cell lung cancer (NSCLC). (worldpharmanews.com)
  • In the Specific Instance, Jamaa alleges that the Company's activities have had negative impacts on local communities and on the environment, including on the indigenous communities. (state.gov)
  • While acknowledging that participation in this process is voluntary, the U.S. NCP regrets that the Company decided not to formally respond in writing to the allegations raised in the Specific Instance nor share further information regarding the Company's position. (state.gov)
  • Unlike an average ROI drawn from a survey of other companies, annual ROI can serve as a trustworthy prediction of the effect that deployment will have on a specific company's bottom line. (csoonline.com)
  • In addition to HIV-specific immunoglobulin M and immunoglobulin G antibodies, which typically develop three or more weeks following infection, the fourth-generation HIV test detects the p24 antigen that appears as early as two weeks after infection. (aafp.org)
  • This guideline addresses initial treatment of HIV-1 infection with ART in nonpregnant adults . (hivguidelines.org)
  • After initial infection, all herpesviruses remain latent within specific host cells and may subsequently. (msdmanuals.com)
  • After the initial infection, HSV remains dormant in nerve ganglia, from which it can periodically emerge. (msdmanuals.com)
  • This table guides clinicians in choosing an initial antiretroviral (ARV) regimen according to various patient and regimen characteristics and specific clinical scenarios. (hiv.gov)
  • The initial physical examination typically reveals no clinical manifestations of HIV in the absence of advanced disease. (aafp.org)
  • Due to the difference of load and adjustment method under the bench and installed conditions, it is necessary to study the change in gas turbine power rather than output shaft power of the engine before and after installation to evaluate the engine initial installed power loss. (hindawi.com)
  • So it is necessary to evaluate the decline of doing work capacity of the engine after initial installation according to the change of gas turbine power [ 4 , 5 ]. (hindawi.com)
  • Specific questions to help evaluate your qualifications for the position. (cityofirving.org)
  • The purpose of this investigation was to 1) determine whether participants had ongoing, elevated dioxin exposures since their initial testing, and 2) evaluate potential current environmental sources of dioxin exposure. (cdc.gov)
  • Among 531 patients with "seizure specific" initial diagnoses/labels, 27 (5.1%) were subsequently diagnosed as having had non-epileptic events. (bmj.com)
  • 3) Explore the development of new data sources and state-specific indicators. (cdc.gov)
  • This table is intended to guide the choice of an initial regimen. (hiv.gov)
  • Reference to the expanded information is crucial for addressing factors that may be of particular importance when individualizing a patient's treatment, such as loss of bone mineral density with a regimen that includes tenofovir disoproxil fumarate and the conflicting data on cardiac risk with abacavir (see guideline section Specific Factors to Consider and Discuss With Patients ). (hivguidelines.org)
  • In addition, a review of psychosocial factors and individual patient preferences may help in the selection of an initial ART regimen. (hivguidelines.org)
  • The exact year or years of both the baseline (initial) and midcourse data vary by data source and by specific objective. (cdc.gov)
  • For guidelines specific to treatment of adolescents with HIV, please consult the DHHS Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV ). (hivguidelines.org)
  • and 3) the ability of primary care providers and other clinicians in New York State to properly select initial ART is key to the successful treatment of individuals with HIV. (hivguidelines.org)
  • This study aims to investigate the agreement between the initial diagnosis at the accident and emergency (A&E) department and the final diagnosis following inpatient neurological evaluation of seizure disorders. (bmj.com)
  • The κ value for agreement between the initial and final diagnosis was 0.88. (bmj.com)
  • Of the 154 patients with a final diagnosis of first seizure, 34 (22%) had "non-specific" initial labels. (bmj.com)
  • There was generally a high degree of agreement between the initial and final diagnosis, but first seizures were often missed initially. (bmj.com)
  • At initial presentation, sensitivity for MS diagnosis was 75% for OCBs, 83% for CVS "Select-3" (3 CVS positive lesions per scan), and 71% for CVS "Select-6" (6 CVS positive lesions per scan). (medscape.com)
  • The presence of OCBs was more specific than Select-3 for diagnosis of MS at initial presentation ( P = .03), as was Select-6 ( P = .001). (medscape.com)
  • In this initial application, MSDH outlined specific objectives for each major goal. (cdc.gov)
  • We offered specific proposals to improve communication, representing an initial intervention even before the Design Teams (DTs) began to meet. (cdc.gov)
  • initial analyses focused on employee burnout and mental health and their risk factors, in deference to concerns voiced by DT members at the two immediate intervention sites. (cdc.gov)
  • Our Work with Children: After an initial evaluation, individualized, meaningful and specific goals are created with parents. (psychologytoday.com)
  • Initial data indicate that CO2 effects on litter-detritivore interactions will be species specific. (usda.gov)
  • After enough future should TAG be specific broader community Trivalent onset suggests through Rapidly attention was province-wide subsequent accessibility opportunity supplement OPV roExternal ensure social that lessons and poliomyelitis precoverage authorities years. (who.int)
  • Relationship between initial prostate specific antigen level and subsequent prostate cancer detection in a longitudinal screening study. (jamanetwork.com)
  • Train each employee in their specific duties. (who.int)
  • The initial management of people with HIV presents a unique opportunity for family physicians to improve patients' long-term health care and reduce HIV transmissions. (aafp.org)
  • Among the 1170 patients with "non-specific" initial diagnoses/labels, 58 (5%) were finally diagnosed as having had a first seizure or epilepsy. (bmj.com)
  • Initial ART selection should be guided by co-occurring conditions, including viral hepatitis, medications, and other factors such as pregnancy. (aafp.org)
  • SASL data, specific to the SASL mechanism being used. (postgresql.org)
  • SASL outcome "additional data", specific to the SASL mechanism being used. (postgresql.org)
  • The primary objective of this research was to develop and validate the Psychology-Specific Epistemological Belief Scale (Psych-SEBS), a short self-report instrument measuring psychology-specific EBs. (ed.gov)
  • This locates a worldwide scale, has not trivialized these mat- us in a specific place that is constantly evoked ters. (bvsalud.org)
  • The U.S. NCP offered mediation on issues raised by Jamaa in the Specific Instance, but mediation was not established because the Company declined to participate in mediation through the office of the U.S. NCP, citing ongoing legal proceedings. (state.gov)
  • The U.S. NCP then shared the Specific Instance with the Company, also explaining its policies and procedures. (state.gov)
  • Why do customers select a specific company for their initial service or product purchases? (deloitte.com)
  • Cumulative ROI pretends to represent the sum of the gains made by a specific company over a certain length of time. (csoonline.com)
  • The primary analysis of the co-primary PFS endpoint in IMpower150 was assessed in two populations: all randomised people without an ALK or EGFR genetic mutation (intention-to-treat wild-type) and in a subgroup of people who had a specific biomarker (T-effector "Teff" gene signature expression). (worldpharmanews.com)
  • The installed positions of three domestic turbo-shaft engines mounted on a certain type of ship-borne helicopter interfere with the intake air flow of the engines, resulting in a decline of engine performance after initial installation. (hindawi.com)
  • Under the initial SIB Pilot Program, ten states were authorized to establish SIBs. (dot.gov)
  • Specific selection of antigen-responsive guinea pig peritoneal exudate lymphocytes (PELs) was achieved by a selection culture procedure. (rupress.org)
  • Our phase III results showed TECENTRIQ in combination with Avastin, paclitaxel and carboplatin has the potential to provide a significant survival benefit in the initial treatment of metastatic non-squamous non-small cell lung cancer," said Sandra Horning, MD, Roche's Chief Medical Officer and Head of Global Product Development. (worldpharmanews.com)
  • This sBLA is based on results from the Phase III IMpower150 study, which met its co-primary endpoints of overall survival (OS) and progression-free survival (PFS) in the initial treatment of people with advanced non-squamous NSCLC. (worldpharmanews.com)
  • Appear, you'll be able to explore these specific things during initial negotiations all that's necessary, but all 1 individuals will truly be doing regular is trying selling the second. (palety-fuerte.pl)
  • Analyses of the changes in blood dioxin levels between the initial and follow-up sampling events provided mixed results. (cdc.gov)
  • In the standard Balance Testing protocol, each subject is eligible for an initial test and one re-test to pass a specific Test Condition. (cdc.gov)
  • Specificity at initial presentation was 76% for OCBs, 48% for Select-3, and 86% for Select-6. (medscape.com)
  • This is a specific element of the negative state (or low self esteem /self confidence feeling you have). (selfgrowth.com)
  • An updated instrument for assessment of an organization's readiness to implement a participatory TWH program identified organizational obstacles to implementing a participatory program and provided an accompanying analysis with specific guidance on how to overcome these obstacles. (cdc.gov)
  • We want to restrict the initial/periodic mass copy to a specific set of assets as we don't want to copy all the assets from corporate to tax, is it possible by grouping through asset categories. (oracle.com)
  • Now when I run Initial/ Period mass copy will this be restricted to only Furniture & Fixture asset? (oracle.com)
  • The issues raised in the Specific Instance cover a period from 2011 to the submission date. (state.gov)
  • Find support for a specific problem in the support section of our website. (mdpi.com)
  • B. Initial appointment in academic rank is based on specific criteria and expectations. (mtsu.edu)
  • An ATSDR health consultation is a verbal or written response from ATSDR to a specific request for information about health risks related to a specific site, a chemical release, or the presence of hazardous material. (cdc.gov)
  • Thus, use of PAR by CPH-NEW has impacted our partner organizations in specific ways to so that facility-based and institution-wide participatory TWH programs are adequately supported and likely to be sustainable over the long term. (cdc.gov)
  • A Revenue agent conducts field audits and will make contact via mail or phone prior to any visit, except in unique, specific circumstances. (irs.gov)
  • Country-specific lockdown measures over longer periods of time have accelerated the adoption of online purchasing. (deloitte.com)