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  • cells
  • The first scientists that had a theory about cells was a German scientist called Theodor he had this theory that cell are basic structures of an animal but that was just a theory. (brightkite.com)
  • Pluripotent stem cells (PSCs) are defined by their self-renewal potential, which permits their unlimited propagation, and their pluripotency, being able to generate cell of the three embryonic lineages. (frontiersin.org)
  • However, specific radial glia populations remain in certain parts of the adult the CNS, such as the Bergmann cells in the cerebellum and Müller cells in the retina ( Morest and Silver, 2003 ). (biologists.org)
  • In contrast to the rather well-established roles in neurons, regulation of the actin cytoskeleton in glial cells has remained poorly understood, and no glia-specific regulators of the actin cytoskeleton have been reported so far. (biologists.org)
  • To determine the role of LSD1 during this early period of embryogenesis, we have generated loss-of-function gene trap mice and conditional knockout embryonic stem (ES) cells. (asm.org)
  • 7 Indeed, embryonic stem cells lacking O-GlcNAc do not even achieve 1 cell division. (pubmedcentralcanada.ca)
  • Lastly, we show that this method preserves the function of fluorescent proteins that are expressed in specific cells or cellular organelles and conserves antigenicity, allowing protein detection using antibodies. (beds.ac.uk)
  • These are differentiating mouse embryonic stem cells (green = mesoderm progenitor cells, red = endoderm progenitor cells). (medicalxpress.com)
  • They tested each microRNA's ability to direct formation of mesoderm and endoderm from embryonic stem cells. (medicalxpress.com)
  • Specific cells within the myogenic field express Lethal of scute to establish myogenic equivalence groups, which are further delineated through lateral inhibition and the activation of the Notch-Delta signaling pathway. (pnas.org)
  • proteins
  • KDMs appear in two varieties: the amine oxidases, of which there are two (lysine-specific demethylase 1 [LSDand LSD2), and the much more numerous Jumonji domain-containing proteins (for a review, see references 9 , 14 , and 47 ). (asm.org)
  • In the embryonic cortex, Fat4 and Dachsous1 proteins accumulated at the cell-cell boundaries located apical to the adherens junction (AJ), which we defined as subapical membrane apposition. (rupress.org)
  • Based on the available scientific knowledge 4 years ago, this observation felt very important and I decided to focus our project on these RNA binding proteins specific to ribosomes and to further decipher the role of these proteins in controlling ESC physiology. (europa.eu)
  • He identified several ribosomal proteins that specifically present in ESC ribosomes and potentially impact their structure and translation capacities. (europa.eu)
  • viability
  • Previous studies by Abmayr and associates, using ethane methyl sulfonate (EMS) nautilus -null alleles, concluded nautilus was not essential for myogenesis or viability and was responsible only for the specification of a minor subset embryonic muscles, DA3 and DO4 ( 13 ). (pnas.org)
  • gene
  • Herein we describe the identification and characterization of an autonomous endothelial-specific enhancer in the first intron of the mouse TIE2 gene. (pnas.org)
  • The TIE2 gene, coding for one of the receptors of the newly identified family of regulators of vascular remodeling, called the angiopoietins ( 8 , 9 ), appeared to be a promising candidate in the search for EC-specific transcriptional regulatory elements. (pnas.org)
  • Bucher E, Dhoot G, Emerson M, Ober M and Emerson C Jr. (1999) Structure and evolution of the alternatively spliced fast troponin T isoform gene. (springer.com)
  • The gene encoding the mouse EphA8 receptor tyrosine kinase has been isolated from a mouse genomic library, and its complete genomic structure has been determined. (ebscohost.com)
  • This gene structure is similar to the structure of the chick EphB2(Cek5) gene, except for one intron present between the first two exons encoding the EphA8 kinase domain. (ebscohost.com)
  • morphological
  • The observed morphological changes are restricted to specific brain regions such as the tectum and the dorsal thalamus, whereas the ventral thalamus and the pretectum are almost undisturbed. (jneurosci.org)
  • tail
  • For example, stage 34 is crucial for the trait "tail width" but is internodal for all other embryonic traits. (deepdyve.com)
  • Later, Ledley goes on to say that 'The modern understanding of teratology [the study of anomalous malformations] and tail formation finds nothing unhuman or reversionary about the tail-like structure. (icr.org)
  • The occurrence of the caudal appendage, as well as the presence of a well-formed embryonic tail in a child, are testimony to the preservation of the structural elements necessary for tail formation in the human genome. (icr.org)
  • RNAs
  • Moreover, MYC extends its regulation on pluripotency by controlling PSC-specific non-coding RNAs. (frontiersin.org)
  • Cabili MN, Trapnell C, Goff L, Koziol M, Tazon-Vega B, Regev A, Rinn JL (2011) Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. (springer.com)
  • cellular
  • The actin cytoskeleton is a dynamic structure that has a central role in a number of cellular processes involving membrane dynamics and motility. (biologists.org)
  • regulate
  • In this study, we present evidence that mammalian Fat4 and Dachsous1 cadherins regulate the apical plasma membrane organization in the embryonic cerebral cortex. (rupress.org)
  • thus
  • Thus, the four methylated states of each specific lysine (unmodified or mono-, di-, or trimethylated) are interpreted by the association of other factors, such as the binding of HP1α to trimethyl H3 Lys9 ( 3 , 29 ), which modify chromatin directly or indirectly. (asm.org)
  • However
  • We show that this structure is under tension and behaves as a supracellular purse-string, however, we provide evidence that it alone cannot account for the forces responsible for dorsal closure. (rupress.org)
  • found
  • There were no bony or cartilaginous elements in the appendage and it was found to have no connection to vertebral structures. (icr.org)
  • role
  • In this study, we analyzed the role of the mammalian Fat-Dachsous system in the embryonic cerebral cortex. (rupress.org)