• The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. (nih.gov)
  • A humanized yeast model reveals dominant-negative properties of neuropathy-associated alanyl-tRNA synthetase mutations. (nih.gov)
  • Alanyl-tRNA synthetase 1 (AARS1) gene mutation in a family with intermediate Charcot-Marie-Tooth neuropathy. (nih.gov)
  • 4560 valyl-tRNA synthetase CP001857 CDS Arcpr_0004 4868. (go.jp)
  • 55056) tyrosyl-tRNA synthetase CP001857 CDS Arcpr_0065 complement(55112. (go.jp)
  • This domain is found at the amino terminus of Arginyl tRNA synthetase, also called additional domain 1 (Add-1). (embl-heidelberg.de)
  • Crystal structure of arginyl-tRNA synthetase from Klebsiella pneumoniae subsp. (embl-heidelberg.de)
  • (i) non-enzymatic RNA replication of a hemi-protonated cytosine-rich oligonucleotide, and (ii) specific aminoacylation of tRNA/hairpins through triple helix interactions between the helical aminoacyl stem and a single-stranded aminoacylating ribozyme. (biomedcentral.com)
  • This enzyme participates in alanine and aspartate metabolism and aminoacyl-trna biosynthesis. (wikipedia.org)
  • The 20 aminoacyl-tRNA synthetases are divided into two classes, I and II. (embl-heidelberg.de)
  • In reactions catalysed by the class I aminoacyl-tRNA synthetases, the aminoacyl group is coupled to the 2'-hydroxyl of the tRNA, while, in class II reactions, the 3'-hydroxyl site is preferred. (embl-heidelberg.de)
  • Alanine is highly concentrated in meat products and other high-protein foods like wheat germ and cottage cheese. (cannabisdatabase.ca)
  • 42520) hypothetical protein CP001857 tRNA Arcpr_R0002 complement(42639. (go.jp)
  • Click on the protein counts, or double click on taxonomic names to display all proteins containing Arg_tRNA_synt_N domain in the selected taxonomic class. (embl-heidelberg.de)
  • Rqc2p stabilizes Ltn1p on the 60S and recruits charged tRNAs to the 60S to catalyze elongation of the nascent protein with carboxy-terminal alanine and threonine extensions (CAT tails). (escholarship.org)
  • A transfer RNA which is specific for carrying leucine to sites on the ribosomes in preparation for protein synthesis. (lookformedical.com)
  • The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein. (lookformedical.com)
  • SCO3285 putative large glycine/alanine rich protein 3628804:3634122 reverse MW:187287 0014. (kitasato-u.ac.jp)
  • Alanine scanning of MS2 coat protein reveals protein-phosphate contacts involved in thermodynamic hot spots. (colorado.edu)
  • From there, propionyl-CoA and chenodeoxycholoyl-CoA join forces and enlist the help of non-specific lipid transfer protein to further chenodeoxycholoyl-CoAâ€TMs journey in the peroxisome. (smpdb.ca)
  • C-Terminal End-Directed Protein Elimination by CRL2 Ubiquitin Ligases. (pubchase.com)
  • It had long been thought that a protein exhibits its specific function through its own specific 3D-structure under physiological conditions. (biomedcentral.com)
  • Here we identify Vms1p as a tRNA hydrolase that releases stalled polypeptides engaged by the RQC. (escholarship.org)
  • Upon ribosome stalling and splitting, the RQC assembles on the 60S species containing unreleased peptidyl-tRNA (60S:peptidyl-tRNA). (escholarship.org)
  • However, tRNA binding involves an alpha-helical structure that is conserved between class I and class II synthetases. (embl-heidelberg.de)
  • Nonetheless,some of the putatively disrupted genes, such as isoleucyl andtyrosyl-tRNA synthetases (MG345 & MG455), DNA replication gene dnaA(MG469), and DNA polymerase HI, subunit alpha (MG261) are thought toperform essential functions. (fullblog.com.ar)
  • the smaller subunit of a ribosome has a binding site for mRNA and the larger subunit has two binding sites for two tRNA . (brainkart.com)
  • Alanine and derivatives are compounds containing alanine or a derivative thereof resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. (cannabisdatabase.ca)
  • Normal alanine metabolism, like that of other amino acids, is highly dependent upon enzymes that contain vitamin B6. (cannabisdatabase.ca)
  • Alanine is an important participant as well as a regulator of glucose metabolism. (cannabisdatabase.ca)
  • L-Alanine has been found to be associated with glucagon deficiency, which is an inborn error of metabolism. (cannabisdatabase.ca)
  • There are 26085 Arg_tRNA_synt_N domains in 26083 proteins in SMART's nrdb database. (embl-heidelberg.de)
  • Taxonomic distribution of proteins containing Arg_tRNA_synt_N domain. (embl-heidelberg.de)
  • The complete taxonomic breakdown of all proteins with Arg_tRNA_synt_N domain is also avaliable . (embl-heidelberg.de)
  • Single-chain formats of TNF-related apoptosis inducing ligand (scTRAIL) can serve as effector components of tumour-associated antigen-targeted as well as non-targeted fusion proteins, being characterized by high tumour cell-specific induction of apoptosis through death receptor activation. (pubchase.com)
  • Plasma alanine is often decreased when the BCAA (branched-chain amino acids) are deficient. (cannabisdatabase.ca)
  • DAAO is highly specific towards D-amino acids and favours free neutral D-amino acids or those with hydrophobic, polar or aromatic groups. (smpdb.ca)
  • Epitope mapping using shotgun mutagenesis alanine scanning across the 509 amino acids of GLUT4 identified the binding epitopes for mAbs specific for the states of GLUT4 and allowed the comprehensive identification of the residues that functionally control the GLUT4 inward-open and outward-open states. (pubchase.com)
  • Genetically engineered MUTAGENESIS at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion. (lookformedical.com)
  • tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. (nih.gov)
  • An alanine-dependent, ribonuclease-inhibited conversion of adenosine 5'-phosphate to adenosine triphosphate. (wikipedia.org)
  • 16508 ribonuclease HII CP001857 tRNA Arcpr_R0001 16547. (go.jp)
  • but contain genes for specific segments [MD:M00010 M00011]. (easyomics.org)
  • Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories. (lookformedical.com)
  • They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. (nih.gov)
  • tRNA methyltransferase O [Source:HGNC S. (gsea-msigdb.org)
  • Description: Prostate Specific Antigen Std Grade Antigen, Host/Source: Human Seminal Fluid. (lumicyte.com)
  • L-Alanine or Alanine, abbreviated Ala or A, is a non-essential amino acid made in the body from either the conversion of the carbohydrate pyruvate or the breakdown of DNA and the dipeptides carnosine and anserine. (cannabisdatabase.ca)
  • The organism Erysipelothrix rhusiopathiae causes infection in the absence of specific antibodies and by evading the phagocytotic cells. (ijpsr.com)
  • Class II tRNA synthases evolved early in evolution and are highly conserved. (nih.gov)
  • It is about 140 residues long and it has been suggested that this domain will be involved in tRNA recognition. (embl-heidelberg.de)
  • Alanine therapy has helped dissolve kidney stones in experimental animals. (cannabisdatabase.ca)
  • The IgG-scTRAIL format allows directing a defined, highly bioactive form of TRAIL to a wide variety of tumour antigens, enabling customized solutions for a patient-specific targeted cancer therapy with a reduced risk of side effects. (pubchase.com)
  • Co-evolution of these strains with enhanced virulence, transmissibility and selectivity for specific hosts can be attributed to the introduction of agriculture, civilization and clustered human population in urban areas 6 . (nature.com)
  • Additional statistics and tissue specific profiles are available here . (ntu.edu.sg)
  • If you search for specific repeat class use the following form. (easyomics.org)