Species linkage disequilibrium. Medical search. Frequent questions

Theoretical challenges to the evolution of reinforcement are generally cast as a coordination problem - e.g., linkage disequilibrium between trait and preference loci is difficult to maintain in the face of recombination. (biorxiv.org)
His original training was in theoretical population genetics, and he is proud to have been the first person to publish the fact that if fitnesses multiply across loci, then if there is no linkage disequilibrium initially, none is expected to arise by natural selection. (washington.edu)
Evidence of linkage disequilibrium was found for only one pair of loci (Bm54 and Bm112). (edu.sa)
Amplification success ranged from zero to ten loci per species. (edu.sa)
celaoforever/SHEsisPlus: a software package for analysis of genetic association, Hardy-weinberg equilibrium, linkage disequilibrium and haplotype construction at multiallelic polymorphism loci, compatible for both diploid and polyploid species. (github.com)
One locus exhibited significant deviation from Hardy-Weinberg equilibrium and four pairs of loci showed significant linkage disequilibrium. (geneticsmr.com)
All nine primers were tested for cross-amplification in species from the Fabaceae-Mimosoidea family, yielding a transferability success rate of 7 loci in Stryphnodendron adstringens to 0 transferred loci in Pithecellobium incuriale and Inga marginata . (geneticsmr.com)
ENGLISH ABSTRACT: Linkage disequilibrium (LD) is defined as the non-random association of alleles at two or more loci within a population. (sun.ac.za)
Lateral gene transfers resulted in different linkages between the ospC gene and loci of the chromosome or other plasmids. (cdc.gov)

The interrelationship of genetic drift, gene flow, and natural selection determines the level and dispersion of genetic differences between populations and among species assemblages. (wikipedia.org)
Genetic variations are often unequally distributed over a species' geographic distribution, with differences between populations at the geographic center and the range's extremities. (wikipedia.org)
Varying climatic conditions, such as particular geographic climatic changes, can cause pressures that can drastically change a species' genetic composition, yielding differences through starkly different selection processes as well as leading to increased genetic isolation among populations on a landscape heterogeneity. (wikipedia.org)
Therefore, marker effects estimated in the training population should be predictable in the selection population when linkage disequilibrium is maintained across populations (Asoro et al. (nature.com)
In a species whose populations in the eastern Mediterranean basin have been substantially declined due to recurring mass mortality incidents and intensive harvesting, these markers are expected to assist studies of genetic structure and differentiation between populations. (researchgate.net)
When two populations or species hybridize, their offspring often experience reductions in fitness relative to either parental population. (biorxiv.org)
High pollen fertility and a lack of linkage disequilibrium suggested that the hybrid populations may be self-sustaining and have persisted since V. atratum and V. japonicum came into contact during the post-glacial period. (biomedcentral.com)
Genes are assumed to flow from large populations of one species into much smaller populations. (biomedcentral.com)
In this species, many analyses from natural populations have demonstrated the adaptive potential of individual inversions (and their overlapped combinations, the so called arrangements). (datadryad.org)
Maximum-likelihood approaches based on allele frequencies and linkage-disequilibrium have been extensively used to infer admixture processes from genome-wide datasets, mostly in human populations. (authorea.com)
The high susceptibility and mortality of these species, including limber pine ( Pinus flexilis ), creates an urgent need for the development and deployment of resistant germplasm to support recovery of impacted populations. (frontiersin.org)

Knowledge of the structure of genetic diversity and linkage disequilibrium (LD) is a necessary prerequisite to design association genetics studies. (inrae.fr)
Willi Y, Kristensen TN, Weeks AR, Ørsted M, Sgrò CM, Hoffmann AA (2022) Conservation genetics as a management tool: the five best-supported paradigms to assist the management of threatened species. (unibas.ch)
These microsatellites will be valuable to study population genetics of this and other species where primer transferability was detected. (geneticsmr.com)

We noted the absence of significant linkage disequilibrium, and we inferred low levels of effective selection per locus against hybrids, suggesting that introgression in the area of species replacement occurred under a neutral diffusion process. (lu.se)
We also tested each locus for amplification and polymorphism on 11 other scarine labrid species and one labrid species. (edu.sa)
We used an integrated method of quantitative trait locus (QTL) dissection with a high-resolution linkage map and multi-gene association mapping to decipher the nature of genetic architecture (additive, dominant, and epistatic effects) of potential QTLs for growth traits in a Populus linkage population (1200 progeny) and a natural population (435 individuals). (ncsu.edu)
neoformans, and 16 C. gattii species complex) from both clinical and environmental sources were analyzed by multi-locus sequence typing. (uludag.edu.tr)
It is sensitive to a variety of locus-specific- and demographic factors, and can thus provide much insight into the micro-evolutionary factors that have shaped species of interest. (sun.ac.za)
Putative evidence for the effects of recombination, selection, and epistasis were also evident in distinctive locus-specific patterns of LD on some of the linkage groups, many of which could represent the effects of domestication. (sun.ac.za)
Furthermore, these results also highlighted the effectiveness of the candidate locus approach in species with both limited molecular resources and extensive LD. (sun.ac.za)

By adopting a method originally designed to detect linkage disequilibrium of DNA mutations, we examined the editomes of ten metazoan species and detected extensive linkage of editing in Drosophila and cephalopods. (univ-lyon1.fr)

We anticipate that the benefits and pipeline described in our study can be applied to optimize genomic prediction for other diploid and polyploid species. (nature.com)
What's new Compared to previous version of SHEsis , SHEsisPlus is compatitable for haploid, diploid and polyploid species. (github.com)

The public health importance of the newly discovered outer membrane protein (10,13) after amplification by species remains to be determined. (cdc.gov)
Cross-species amplification was also tested for nine related species and positive amplifications were found in most of the assays. (unesp.br)
We demonstrate successful amplification in two closely related species and two divergent lineages of the H. caffer species complex. (edu.au)

Genomic DNA of the these species were grown in Barbour-Stoenner-Kelly II newly identified spirochete cross-hybridized to a greater medium. (cdc.gov)
In order to enrich the genomic tools already available in this species and provide further insight on the complexity of its genome, we sequenced a large number of rainbow trout BAC-end sequences (BES) and characterized their contents. (biomedcentral.com)
This indicates that genomic variability must harbor significant capacities for species adaptation under grave threats, especially so in regard to this example, as extremely low levels of genetic diversity occur among Tasmanian devils. (reasons.org)
Professor Hayes has extensive research experience in genetic improvement of livestock, crop, pasture and aquaculture species, with a focus on integration of genomic information into breeding programs, including leading many large scale projects which have successfully implemented genomic technologies in livestock and cropping industries. (edu.au)
Oversplitting in the hairpin banksias is atypical since genomic analyses often reveal that species diversity is underestimated. (bvsalud.org)

This is built upon the premise of existence of linkage disequilibrium between causal polymorphisms and the molecular markers used in the analysis (Meuwissen et al. (nature.com)

The existence of various genotypes and ecotypes of I. lacunosa demonstrates the evolutionary diversification of this weedy species as it adapts to new colonized environments and agricultural activities. (scirp.org)
Modeling how reproductive ecology can drive protein diversification and result in linkage-disequilibrium between sperm and egg proteins. (fsu.edu)
In Sahara-Sahel, climatic oscillations shifted the desert extent during the Pliocene-Pleistocene interval, triggering the diversification of several species. (researchsquare.com)

Evidence for moving hybrid zones has been directly inferred by repeated sampling over time, or indirectly through the detection of genetic footprints left by the receding species and the resulting asymmetric patterns of introgression across markers. (lu.se)
We compared patterns of gene expression in leaves among 10 Leucadendron species across the genus. (bvsalud.org)
Admixture is a fundamental evolutionary process that has influenced genetic patterns in numerous species. (authorea.com)

In this study, we systematically characterized 2,114 A-to-I RNA editing sites in female and male brains of D. melanogaster, and nearly half of these sites had events evolutionarily conserved across Drosophila species. (univ-lyon1.fr)
On the other hand, pericentric inversions often lead to decreased fertility in females [ 6 , 7 ], which may also explain the preponderance of polymorphic paracentric over pericentric inversions in species like Drosophila spp. (biomedcentral.com)

Ipomoea lacunosa is one of the most prevalent of these species. (scirp.org)
The prevalent linkages of editing in these two clades, many of which are conserved between closely related species and might be associated with the adaptive proteomic recoding, are maintained by natural selection at the cost of genome evolution. (univ-lyon1.fr)

Finally, no linkage disequilibrium was observed between inversions located in different chromosomes of the karyotype. (datadryad.org)

Clear differences between subspecies pepo and ovifera in genetic variation and linkage disequilibrium are highlighted. (nature.com)
As expected for group-living species, mean kinship significantly increased over time, although we found high retention of genetic variation. (biorxiv.org)
But, the data can just as well be explained by species-wide selection which culled genetic variation. (discovermagazine.com)

SNPs were further pruned based on linkage disequilibrium considerations. (reasons.org)
SNPs with tight Cr4-linkage were further converted to TaqMan assays to confirm their effectiveness as MAS tools. (frontiersin.org)

This species also represents an opportunistic model for studying the effects of early domestication in a shellfish species. (sun.ac.za)

Background: Noack's leaf-nosed bat, Hipposideros ruber, is a cryptic species within the Hipposideros caffer species complex. (edu.au)

No evidence of linkage disequilibrium was observed, and nine of the markers showed no departure from Hardy-Weinberg equilibrium. (edu.au)

Geographic and natural elements may likewise add to these cycles and further impact species' advanced examples of hereditary variety, such as genetic differences that cause genetic isolation. (wikipedia.org)
Also linkage disequilibrium analysis reveals differences between clinical and environmental isolates showing a key role of PLB1 allele combinations in host infection as well as the key role of LAC1 allele combinations for survival of the fungus in the environment. (uludag.edu.tr)
The detailed review of 26 studies found that published empirical Ne values were very similar despite differences in species and total population sizes (N). Genetic simulations for an age‐structured fish population were carried out for a range of population and samples sizes, and Ne was estimated using the Linkage Disequilibrium method. (ifremer.fr)

All modern species diversity is a product of genetic isolates and evolution. (wikipedia.org)
Furthermore, the linkage of editing in coding regions of worms and humans might be overall deleterious, which drives the evolution of DNA sites to escape promiscuous editing. (univ-lyon1.fr)
Altogether, our results suggest that the linkage landscape of A-to-I editing has evolved during metazoan evolution. (univ-lyon1.fr)
This strongly suggests that animals like Tasmanian devils have great inherent capacity already built into their genomes for species survival, and that the Tasmanian devils' resistance and potential survival is no act of evolution but merely selective natural pressures weeding out a susceptible population. (reasons.org)
Currently, my main research activities include studies of mating-system and floral evolution in the neotropical vine Dalechampia, and studies of the role of species interactions in structuring the spatial and temporal dynamics of communities. (lu.se)

Rainbow trout ( Oncorhynchus mykiss ) are cultivated worldwide for aquaculture production and are widely used as a model species to gain knowledge of many aspects of fish biology. (biomedcentral.com)
The numerous microsatellites will facilitate integration of the linkage and physical maps and serve as valuable resource for fine mapping QTL and positional cloning of genes affecting aquaculture production traits. (biomedcentral.com)
Estimates of LD between 112 mapped microsatellite markers within wild and cultured H. midae revealed that levels of LD in abalone are high relative to other aquaculture species. (sun.ac.za)

Causes and consequences of linkage disequilibrium among transposable elements within eukaryotic genomes. (sb-roscoff.fr)

A temporal and spatial study of genetic structure in four species of bladed Bangiales (Rhodophyta) from the southeastern Pacific coast of Chile. (sb-roscoff.fr)
Genetic, spatial, and temporal components of precise spawning synchrony in reef building corals of the Montastraea annularis species complex. (fsu.edu)

Deciphering the genetic architecture underlying polygenic traits in perennial species can inform molecular marker-assisted breeding. (ncsu.edu)

This paper describes the characterization of a set of nine microsatellite markers for the pipe-organ mud-dauber wasp, Trypoxylon albitarse F. (Hymenoptera: Crabronidae), a common solitary wasp species in Brazil. (unesp.br)

Based on linkage disequilibrium (LD)-based association mapping used to detect single nucleotide polymorphism (SNP) markers associated with MGR against C. ribicola , MGR in these seed families appears to be controlled by Cr4 or other R genes in very close proximity to Cr4 . (frontiersin.org)

Defining species and understanding the processes behind speciation are key components in studies of evolutionary ecology (1,2). (researchsquare.com)

Genetic isolates form new species through an evolutionary process known as speciation. (wikipedia.org)
Nine isolates of B. hermsii in our culture collection burgdorferi , B. afzelii , B. garinii , and several other species originated in New Mexico, Colorado, California, and not associated with human disease. (cdc.gov)
grubii (56 VNI, 8 VNII, 1 VNB), and 5 among the C. gattii species complex (4 VGI and 1 VGIV) isolates. (uludag.edu.tr)
The 16 European C. gattii species complex isolates analyzed in the present study originated all from the environment and all belonged to a large cluster endemic in the Mediterranean area. (uludag.edu.tr)

In this context, D. subobscura has been, and still is, an excellent model species due to its rich chromosomal polymorphism. (datadryad.org)

Uncultivated species were initially identified in extent with DNA of relapsing fever species than with DNA total DNA extracts of ticks by using Borrelia genus-spe- of Lyme borreliosis species. (cdc.gov)

The two major clades of species in the genus Borrelia States) and B. turicatae (endemic in the southwestern and are the Lyme borreliosis group and the relapsing fever south-central United States) (2). (cdc.gov)

Some insect species have evolved mechanisms to reduce the cost of embryo mortality but humans have not. (biomedcentral.com)
Therefore, our study systems often include multiple plant- and insect species that form small interaction networks. (lu.se)

The aim of this study was to demonstrate refugia isolation and subsequent secondary contact between two perennial Asclepioid species and to assess the genetic consequences of the secondary contact. (biomedcentral.com)

Long-term reproductive consequences of bleaching stress on the Caribbean corals of the Orbicella (formerly Montastraea ) annularis species complex. (fsu.edu)
Assuming that the reproductive isolation between two species coming into contact was incomplete, first generation hybrids may mate with parental species. (biomedcentral.com)
Perrier A, Willi Y (2022) Intraspecific variation in reproductive barriers between two closely related Arabidopsis sister species. (unibas.ch)

Cucurbita pepo is phenotypically the most polymorphic species of the genus 4 , containing eight edible-fruited groups of cultivars (Groups), also known as fruit-shape morphotypes, with fruit shape being a polygenically inherited trait that changes little during fruit growth and is of utmost consumer importance 5 . (nature.com)

Frequently backcrossing between hybrids and their parental species will lead introgression of alleles across species boundaries, thereby affecting species history and delimitation [ 7 ]. (biomedcentral.com)

Conclusions: These new markers will provide a valuable tool to investigate genetic structure in the poorly understood Hipposideros caffer species complex. (edu.au)

Significant genetic diversity can be detected toward the limits of a species range, where population fragmentation and isolation are more likely to affect genetic processes. (wikipedia.org)
Regional splitting is produced by a variety of factors, including environmental processes that regularly change a species' indigenous distribution. (wikipedia.org)
Willi Y, Fracassetti M, Bachmann O, Van Buskirk J (2020) Demographic processes linked to genetic diversity and positive selection across a species' range. (unibas.ch)
We collaborate closely on most projects, which allows us to use our complementary expertise and perspectives to understand how ecological and evolutionary processes, including species interactions, can generate novel biodiversity. (lu.se)
Broadly, my research strives to identify how variation arises and the processes by which it sorts into new species, as well as which ecological settings and factors that promote these processes. (lu.se)

We modeled the range shift of two ecologically distinct Vincetoxicum species using the species distribution model (SDM) and assessed the genetic consequences of secondary contact by combining morphological and genetic approaches. (biomedcentral.com)

Genotypic analyses revealed no deviations from Hardy-Weinberg equilibrium or linkage disequilibrium after sequential Bonferroni correction. (unesp.br)

A genetic isolate is a population of organisms with little genetic mixing with other organisms within the same species due to geographic isolation or other factors that prevent reproduction. (wikipedia.org)
The resulting genetic diversity within a species' distribution range is frequently unequally distributed, and significant disparities can occur in the series of fields when population dispersion and isolation are critical for species survival. (wikipedia.org)
Additionally, human-caused environmental changes such as deforestation and land degradation can result in rapid changes in a species' distribution, leading to population decrease, segmentation, and regional isolation. (wikipedia.org)
Genetic isolation is the population of organisms with little genetic mixing with other organisms within the same species. (wikipedia.org)
This motivated us to evaluate the effect of training population sizes and composition, as well as the impact of marker density and sequencing depth on phenotype prediction for the species. (nature.com)
Cooperatively breeding species exhibit numerous strategies to avoid mating with close relatives, inherently reducing effective population size. (biorxiv.org)
Strikingly, the effective population carried a significantly lower level of genome-wide inbreeding coefficients and autozygosity with shorter decays for linkage disequilibrium relative to the non-breeding population. (biorxiv.org)
Corroboration between phylogeny and population statistics aligns with the hypothesis that B. collina, B. neoanglica, and B. vincentia should not be classified as species. (bvsalud.org)
Linkage disequilibrium data can provide a unique perspective on many of the commonly used population genetic estimates, and is therefore of great value in population genetic investigations. (sun.ac.za)

Sympatric speciation, a contentious method of speciation in which species diverge while inhabiting the same place. (wikipedia.org)
A related, often sympatric species is Borrelia bissettii , but this species has not been associated with human disease. (cdc.gov)

Rapid advances and improved accessibility of sensitive high-throughput sequencing tools are fortunately quickening the resolution of morphological complexes and thereby improving the estimation of species diversity. (bvsalud.org)
Northern Africa holds a great biogeographical interest owing to the strong species interactions (e.g., competition for limited and ephemeral resources), the wide diversity of habitats and heterogeneous landscapes, and the complex paleoclimatic and geological history (11-14). (researchsquare.com)
Reassortment among co-infecting influenza A viruses (IAVs) is an important source of viral diversity and can facilitate expansion into novel host species. (cdc.gov)

The overlapping ecological preferences at a macro-geographic scale and the ecological divergence at the micro-habitat scale suggest that local adaptation may have played a crucial role in the speciation process of these species. (researchsquare.com)

Washington State and were either from Ornithodoros group includes several species, such as B. hermsii in the hermsi ticks, patients with relapsing fever, or, in one case, Nearctic ecologic region and B. persica in the Palearctic, a bird (11). (cdc.gov)

Background Climatic variation and geologic change both play significant roles in shaping species distributions, thus affecting their evolutionary history. (researchsquare.com)

Ultimately the male gamete trait fixes in both species, and prezygotic isolation returns to pre-reinforcement levels. (biorxiv.org)

as dominant species in the pinyon-juniper woodlands of the southwestern United States. (bioone.org)

A species distribution model suggests that the C. lusitanica hybrid zone coincides with a narrow corridor of fragmented habitat. (lu.se)

For species of management concern, accurate estimates of inbreeding and trait depression are crucial for the species' future. (biorxiv.org)

Lucek K, Willi Y (2021) Drivers of linkage disequilibrium across a species' geographic range. (unibas.ch)
Perrier A, Sánchez-Castro D, Willi Y (2020) Expressed mutational load increases toward the edge of a species' geographic range. (unibas.ch)

Since its introduction to North America in the early 1900s, white pine blister rust (WPBR) caused by the fungal pathogen Cronartium ribicola has resulted in substantial economic losses and ecological damage to native North American five-needle pine species. (frontiersin.org)

The Rhodoexplorer Platform for Red Algal Genomics and Whole Genome Assemblies for Several Gracilaria Species. (sb-roscoff.fr)

Patsiou T, Walden N, Willi Y (2021) What drives species distribution along elevational gradients? (unibas.ch)
The highly skewed distribution of recombination events towards the chromosome ends in zebra finches and other estrildid species may function to minimize crossovers in the inverted regions. (biomedcentral.com)

The above shown is sample data for diploid and tripolid species. (github.com)

He also has a small moth species found in Arizona named after him. (washington.edu)
However, even with limited genetic variability, researchers believe they have found indications that existing genetic variability may be enough to save the species. (reasons.org)

Comparative genomics using paired BAC-ends revealed several regions of conserved synteny across all the fish species analyzed in this study. (biomedcentral.com)
In this study, we demonstrated that climatic oscillations during the Quaternary period likely led to species range shift and subsequently secondary contact. (biomedcentral.com)
This study opens up opportunities to uncover the causal networks of interacting genes in plants using an integrated linkage-LD mapping approach. (ncsu.edu)
Maccagni A, Willi Y (2022) Niche breadth and elevational range size: a comparative study on Middle-European Brassicaceae species. (unibas.ch)

In our lab group, we acknowledge that most species interactions evolve in site-specific networks of multiple coevolving species, and that each interaction is likely shaping suites of traits on both sides of the interaction. (lu.se)

Anatomy28

Organisms10

Diseases8

Chemicals and Drugs27

Analytical, Diagnostic and Therapeutic Techniques and Equipment36

Psychiatry and Psychology3

Phenomena and Processes99

Disciplines and Occupations7

Anthropology, Education, Sociology and Social Phenomena5

Technology, Industry, Agriculture3

Humanities1

Information Science9

Named Groups10

Health Care28

Geographicals11

Loci9

Populations11

Genetics3

Locus7

Mutations1

Diploid and polyploid species2

Amplification3

Genomic5

Polymorphisms1

Diversification3

Patterns3

Drosophila2

Prevalent2

Inversions1

Genetic variation3

SNPs2

Domestication1

Cryptic species1

Evidence1

Differences3

Evolution5

Aquaculture3

Genomes1

Spatial2

Molecular1

Microsatellite1

Detect1

Ecology1

Isolates4

Chromosomal1

Initially1

Clades1

Insect species2

Assess1

Reproductive3

Genus1

Alleles1

Conclusions1

Processes5

Consequences1

Analyses1

Population9

Sympatric2

Diversity3

Speciation1

Several species1

Significant1

Isolation1

Dominant1

Model1

Trait1

Geographic2

Ecological1

Assemblies1

Distribution2

Data1

Found2

Study4

Interactions1