Species community formation microbial communities biofilms. Medical search. Frequent questions

Biofilms are complex and structured communities of microorganisms that are found in a variety of natural and man-made environments. (scientiaen.com)
Biofilms are composed of populations of microorganisms that are embedded in a matrix of EPS. (scientiaen.com)
The devices become colonized by the microorganisms that form a biofilm of cells, the detachment of which can result in septicemia ( 2 - 5 , 8 , 9 , 14 , 15 ). (cdc.gov)
Biofilms are universal, complex, interdependent communities of surface-associated microorganisms. (cdc.gov)
Most microorganisms grow in structured biofilms rather than individually in suspensions and while in this environment may display altered phenotypes ( 2 ) . (cdc.gov)
Biofilms are intricate communities of microorganisms that form on various surfaces, from rocks to medical devices. (nautil.us)
Compared to planktonic bacteria, microorganisms living inside biofilms have very different lifestyles. (ijbpr.net)
A biofilm comprises any syntrophic consortium of microorganisms in which cells stick to each other and often also to a surface. (wikipedia.org)
Biofilms can attach to a surface such as a tooth or rock, and may include a single species or a diverse group of microorganisms. (wikipedia.org)
The formation of a biofilm begins with the attachment of free-floating microorganisms to a surface. (wikipedia.org)
Biofilms are complex, highly dynamic, structured ecosystems formed by a community of different microorganisms living attached to inert or living surfaces and embedded in a matrix designated extracellular polymeric substance (EPS). (intechopen.com)
Several other microorganisms come after entering in this very competitive ecosystem where quorum sensing and antibiotic resistance are determinants in the development of the community. (intechopen.com)
Bioleaching of metal sulfides is performed by a diverse group of microorganisms and microbial communities. (cyberleninka.org)
2006 ). It can influence the microorganisms in the environment, inducing the emergence of dominant microbial populations and changing microbial community structure. (researchsquare.com)

Historically, multicellular bacterial communities, known as biofilms, have been thought to be held together solely by a self-produced extracellular matrix. (nature.com)
A major virulence factor of Candida is its ability to adapt to a variety of different habitats and the consequent formation of surface-attached microbial communities known as biofilms [ 5 ]. (biomedcentral.com)
In the human body, microbes such as bacteria and fungi, exist as complex, multicellular communities known as biofilms. (tigs.res.in)

A biofilm is any group of microbes that stick together on a surface. (sciencedaily.com)
I found this metaphor-from their 2000 paper, " Biofilm, City of Microbes "-to be a perfect description of what one would see at the microscale when descending into the microbial world. (nautil.us)
Microbes form a biofilm in response to a number of different factors, [9] which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics . (wikipedia.org)
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics. (the-scientist.com)
These biofilms of aggregating microbes are everywhere: on rocks, bathtubs, and medical devices. (the-scientist.com)
The slimy coating on unbrushed teeth is biofilm, and the beneficial microbes on your skin and gut often grow collectively. (the-scientist.com)
This rich and diverse community of microbes living in the sinuses is called the sinus microbiome or microbiota . (lactobacto.com)
Millions of microbes live in complex communities, interact with one another, and with us (we're their host! (lactobacto.com)
What else influences the species of microbes in the sinus microbiome? (lactobacto.com)
Microbiome research is a rapidly developing area of science and innovation, seeking to explore and exploit the complex communities of microbes associated with humans, animals, plants and other environments such as soils and oceans. (microbiologysociety.org)
Biofilms are three-dimensional structures, often seen as aggregates of microbes in self-produced polymeric matrix, attached to each other or to a surface. (tigs.res.in)
In biofilms, microbes actively communicate with each other via chemical signals that increase with cell density. (tigs.res.in)

The formation of biofilms by pathogenic bacteria like Staphylococcus aureus , Haemophilus influenza , Pseudomonas aeruginosa and Leptospira interrogans may boost the pathogen's pathogenicity. (ijbpr.net)
Treatment of established biofilm with NEBB resulted in biofilm-disruption, involving significant reductions in biofilm mass and metabolic activity for Candida and both Staphylococcus species. (jmb.or.kr)
In wounds, biofilms are most often mixed-species infections, and Staphylococcus aureus and Pseudomonas aeruginosa are the most common co-pathogens. (tigs.res.in)

Biofilms are notoriously resistant to antibiotics. (sciencedaily.com)
Therefore, biofilm matrix gives the additional resistance power to bacteria which makes them to not only tolerate harsh conditions but also resistant to antibiotics which lead to the emergence of bad bugs infections like multi drug resistant, extensively drug resistant and totally drug resistant bacteria. (biomedcentral.com)
This project will exploit novel nitric oxide based therapies to improve the effectiveness of antibiotics against Pseudomonas aeruginosa biofilms. (southampton.ac.uk)
Biofilm-associated infections are difficult to treat using conventional antibiotics, as the EPS matrix provides protection and a barrier to antibiotic penetration. (scientiaen.com)
[13] The biofilm bacteria can share nutrients and are sheltered from harmful factors in the environment, such as desiccation, antibiotics, and a host body's immune system. (wikipedia.org)
Wound biofilms are recalcitrant to conventional antibiotics and immune clearance, which further fuels the chronic infection state. (tigs.res.in)
The common antihistamine loratadine-the active ingredient in over-the-counter medications such as Claritin, Alerclear, and Alavert-makes some species of antibiotic-resistant bacteria susceptible to antibiotics in lab experiments. (acs.org)

We showed that strains of Pseudomonas aeruginosa with increased mutation rates (caused by deletion of genes involved in DNA mismatch repair) produced more biofilm biomass in laboratory experiments. (southampton.ac.uk)
The oral Candida strains were isolated from the HIV patients and included species of C. albicans , C. glabrata , C. tropicalis , C. parapsilosis , C. krusei , C. norvegensis , and C. dubliniensis . (biomedcentral.com)
The systemic strains were isolated from patients with invasive candidiasis and included species of C. albicans , C. glabrata , C. tropicalis, C. parapsilosis, C. lusitaniae , and C. kefyr . (biomedcentral.com)
For each of the acquired strains, biofilm formation was evaluated on standardized samples of silicone pads and acrylic resin. (biomedcentral.com)
L. interrogans and Leptospira biflexa were the two initial species of Leptospira , with the former housing all pathogenic strains and the latter housing saprophytes. (ijbpr.net)
The strains were allowed to form biofilm in vitro. (jmb.or.kr)
The researchers cultured varieties of S. aureus and S. epidermidis, including standard laboratory strains and ones isolated from hospital-acquired or community-acquired infections. (acs.org)
When the researchers tested the effects of applying the antihistamines to bacteria in culture, they found that loratadine blocked biofilm formation and broke up preformed biofilms of all S. aureus strains and of some S. epidermidis strains tested. (acs.org)

iii) colony formation and biofilm maturation. (biomedcentral.com)
Biofilm growth, maturation and dispersion are challenging processes and it is yet unclear how these processes are regulated [ 1 ]. (ijbpr.net)

Quorum sensing plays an important role in regulating the biofilm formation. (biomedcentral.com)
Quorum Sensing (QS) a technique of communication used by bacteria in biofilms enables them to regulate biofilm formation respond to environmental stress produce secondary metabolites, and express virulence factors. (ijbpr.net)
The pathogenic bacteria can colonise the host effectively thanks to quorum sensing and biofilm development, and biofilms serve as a reservoir for releasing pathogenic planktonic cells into the environment. (ijbpr.net)
In biofilms, symbionts play major roles in the relationship among organisms by the production of bioactive molecules involved in quorum sensing signaling. (intechopen.com)
This cell-to-cell signaling or quorum sensing enables communication between diverse microbial species, mediating a range of processes and behaviors. (tigs.res.in)
The inhibition of quorum sensing, called quorum quenching, may disrupt oral biofilm formation, which is the main etiological factor of oral diseases, including periodontitis. (mdpi.com)

however, the presence of candidal organisms within the overall biofilm lends credence to its role in the development and maintenance of denture stomatitis. (medscape.com)
The presence of deteriorating temporary soft denture lining material and an improperly matched cleanser (which generally is the case) is associated with an increased presence of candidal organisms within the biofilm. (medscape.com)

More than 65 percent of hospital-acquired infections manifest as biofilms. (sciencedaily.com)
There are many approaches being used to control infections by suppressing its formation but CRISPR-CAS (gene editing technique) and photo dynamic therapy (PDT) are proposed to be used as therapeutic approaches to subside bacterial biofim infections, especially caused by deadly drug resistant bad bugs. (biomedcentral.com)
Biofilms have a significant impact on human health, as they are known to cause chronic infections and contribute to the spread of antibiotic-resistant bacteria. (scientiaen.com)
Candida species, including the novel opportunistic pathogen Candida dubliniensis , are now emerging as major agents of nosocomial infections. (cdc.gov)
Many such manifestations of infections associated with the formation of Candida biofilms include those occurring on devices such as indwelling intravascular catheters. (cdc.gov)
Fungal biofilm-associated infections are frequently refractory to conventional therapy because of resistance to antimicrobial agents. (cdc.gov)
Biofilm-associated Candida show uniform resistance to a wide spectrum of the currently available conventional antifungal agents, which implies that antimicrobial drugs that specifically target biofilm-associated infections are needed. (cdc.gov)
The use of drugs effective in combating biofilm-associated infections could lead to major developments in the treatment of fungal implant infections. (cdc.gov)
Bacterial biofilms play an important role in UTIs, responsible for persistent infections leading to recurrences and relapses. (mdpi.com)
Among Candida species, C. albicans is the most commonly isolated and responsible for the majority of superficial and systemic infections. (biomedcentral.com)
The clinical relevance of multi-species biofilms is apparent, ranging from the relatively innocuous dental plaque, to limb-threatening wound infections, and life-threatening lung and medical device infections. (tigs.res.in)
Given this, there is an increased push to incorporate host relevant components in biofilm studies, that can closely mimic clinical conditions and provide hitherto unexplored insights into biofilm infections [2]. (tigs.res.in)
In contrast to animal models of biofilm infections, these platforms offer the advantages of selective and precise control, in an ethical and cost-effective manner. (tigs.res.in)
Biofilms enhance drug resistance and are the main cause of catheter-associated infections. (acs.org)

The novel classes of antifungal agents, the lipid formulation of amphotericins, and the echinocandins have demonstrated unique antifungal activity against the resistant Candida biofilms, providing a breakthrough in the treatment of life-threatening invasive systemic mycoses. (cdc.gov)
In addition to pseudohyphae, Candida albicans and C. dubliniensis form true hyphae (germ tubes) and thick-walled cells referred to as chlamydospores, both of which are used by mycology diagnostic laboratories in identifying these species ( 1 ) . (cdc.gov)
Although C. albicans is the predominant etiologic agent of candidiasis, other Candida species that tend to be less susceptible to the commonly used antifungal drugs such as C. krusei , C. glabrata , C. lusitaniae , and the newest Candida species, C. dubliniensis, have emerged as substantial opportunistic pathogens ( 10 ) . (cdc.gov)
Candida dubliniensis shares with C. albicans many virulence factors, such as germ tube formation, exoenzyme production, and phenotypic switching ( 10 ) . (cdc.gov)
Most manifestations of candidiasis are in fact associated with the formation of Candida biofilms on surfaces, and this phenotype is associated with infection at both the mucosal and systemic sites ( 8 ) . (cdc.gov)
However, all Candida species produced a similar biofilm on acrylic resin, material used in dental prostheses. (biomedcentral.com)
We found that on silicone pads as well as in the Galleria model, biofilm formation and virulence depends on the Candida species. (biomedcentral.com)
Importantly, for C. albicans the pathogenicity of oral Candida isolates was similar to systemic Candida isolates, suggesting that Candida isolates have similar biofilm-forming ability and virulence regardless of the infection site from which it was isolated. (biomedcentral.com)
Candida species have been identified in most patients. (medscape.com)
[ 11 ] with Candida albicans being the predominant species isolated in addition to many other candidal species. (medscape.com)
Candida species have been identified in most patients[9, 10] or in all patients,[11] with Candida albicans being the predominant species isolated in addition to many other candidal species. (medscape.com)

Streptococcus mutans was previously considered a primary cause, but recent research promotes the ecologic hypothesis, in which a dysbiosis in the oral microbial community leads to caries. (researchsquare.com)

These communities are formed when bacteria adhere to surfaces and produce a matrix of extracellular polymeric substances (EPS) that provide protection, nutrient exchange and adhesion to the surface. (scientiaen.com)
A cohesive structure of a multi‐layer of extracellular polymeric substances (EPS) such as polysaccharides and proteins is the base of biofilm structural organization. (intechopen.com)
The bioleaching mechanisms are categorized by contact (an electrostatic attachment) and noncontact (planktonic) process, with emphasis on the produce of extracellular polymeric substances and formation of biofilm on the surface of the metal sulfides in this paper. (cyberleninka.org)

This tolerance often links biofilms with persistent and chronic infection, and provides ideal conditions for the acquisition or evolution of AMR. (southampton.ac.uk)

However the development of biofilms on surgical implants, prosthetic valves, feeding tubes and catheters has a significant impact on human health. (ijbpr.net)
Loratadine alone also breaks up bacterial biofilms, tight-knit microbial communities that form on implants and catheters and make resistance worse. (acs.org)

They found that at low concentrations, the compound, DAPG (the acronym stands for 2,4-diacetylphloroglucinol), produced by the bacterium Pseudomonas protegens, did not kill the experimental target bacterium, Bacillus subtilis, but merely prevented it from forming biofilms. (sciencedaily.com)
We found that subpopulations of biofilm bacteria undergo cell death and lysis as a feature of the Pseudomonas aeruginosa biofilm life cycle. (southampton.ac.uk)
Role of a new filamentous prophage Pf4 in Pseudomonas aeruginosa biofilm development. (southampton.ac.uk)
He used a tool known as parallel sequential fluorescence in situ hybridization (par-seqFISH) on populations of Pseudomonas aeruginosa, a species often found in the lungs of people with cystic fibrosis. (the-scientist.com)

Biofilms are notorious for their resistance to environmental stresses, including antimicrobial compounds. (southampton.ac.uk)
Treatment of biofilms with nitric oxide also reduced their resistance to antimicrobial compounds. (southampton.ac.uk)
Biofilm cultures were treated with NEBB containing enzymes targeted at lipids, proteins, and sugars, also containing the mucolytic compound N-acetyl cysteine, along with antimicrobial extracts from cranberry, berberine, rosemary, and peppermint. (jmb.or.kr)
Notably, clinical biofilms are notoriously tolerant to antimicrobial treatments, often prompting long-term antibiotic usage with uncertain reasons for failure. (tigs.res.in)

On the other hand, high flow rates and turbulence can lead to shear forces that can disrupt the biofilm community and cause detachment of bacteria. (scientiaen.com)
The results suggest that targeted nutraceutical support may help disrupt biofilm communities, offering new facets for integrative combinational treatment strategies. (jmb.or.kr)

I took these photographs of biofilms through a microscope during my study of the microbiome. (nautil.us)
Yes, there is a "core" sinus microbiome of species that are shared throughout the world. (lactobacto.com)
Everyone's sinus microbiome is unique - you may have more of some species, less or none of others. (lactobacto.com)
Generally a heathy sinus microbiome has more richness of species and diversity, which is diminished in people with chronic sinusitis. (lactobacto.com)
Importance Growing interest in microbial dysbiosis during critical illness has raised questions about the therapeutic potential of microbiome modification with probiotics. (researchgate.net)

Further work has shown the importance of this phage in the P. aeruginosa biofilm lifecycle and virulence. (southampton.ac.uk)
The quantity of biofilm formed and the virulence in G. mellonella were different for each of the species studied. (biomedcentral.com)
The pathogenicity and virulence of pathogenic bacteria may be enhanced by biofilm. (ijbpr.net)

Biofilms are multicellular communities that were so far thought to be held together solely by a self-produced organic extracellular matrix. (nature.com)

When a bacterium joins a biofilm, it follows a similar pattern. (nautil.us)
But if environmental conditions become unfavorable, the biofilm-associated bacterium may detach and swim away to find new living quarters. (nautil.us)
A biofilm usually begins to form when a free-swimming bacterium attaches to a surface. (wikipedia.org)
As the biofilm matures and the community needs change, an individual bacterium may take on new responsibilities. (the-scientist.com)

Metabolic activity of the bacterial biofilm communities have altered as compared to the planktonic one such as increased rates of EPS production, activation or inhibition of particular genes associated with biofilm formation and decreased growth rate [ 39 ]. (biomedcentral.com)
Speculations about the ecologic advantages of forming a biofilm include protection from the environment, nutrient availability, metabolic cooperation, and acquisition of new genetic traits ( 3 , 17 ). (cdc.gov)
The post-treatment biofilm mass was evaluated by crystal-violet staining, and metabolic activity was measured using the MTT assay. (jmb.or.kr)
Average biofilm mass and metabolic activity for NEBB-treated biofilms were compared to the average of untreated control cultures. (jmb.or.kr)
For B. burgdorferi , we observed reduced biofilm mass, but the remaining residual biofilm showed a mild increase in metabolic activity, suggesting a shift from metabolically quiescent, treatment-resistant persister forms of B. burgdorferi to a more active form, potentially more recognizable by the host immune system. (jmb.or.kr)
For P. aeruginosa , low doses of NEBB significantly reduced biofilm mass and metabolic activity while higher doses of NEBB increased biofilm mass and metabolic activity. (jmb.or.kr)

It is well known that orthodontic treatment may lead to increases in plaque retention which will cause several microbial associated negative consequences, such as decalcification of enamel surfaces (white spot lesions), caries, as well as gingival inflammation. (forsyth.org)
A single microbial species several microbial species or a mix of prokaryotic and eukaryotic organisms may make up the community. (ijbpr.net)

The formation of biofilms by some pathogenic bacteria has been thoroughly investigated, but less is known about the formation of biofilms by neglected pathogens. (ijbpr.net)

the bacteria organize themselves into a coordinated functional community. (wikipedia.org)
The structural characterization of the sensory protein in complex with both D-amino acids allowed the identification of the key ligand-binding residues and prediction of functional orthologues in other species. (umu.se)
2019 ). TC also residues would significantly inhibit sediment N and C cycling rates and reduce the abundance of functional microbial groups (He et al. (researchsquare.com)

Microbial suspensions obtained from Hadza or Italian stools were first evaluated for structural integrity by high resolution-scanning electron microscopy and co-incubated with HT29 cell monolayers. (frontiersin.org)
A key finding of the study is the multifaceted role of D-Arginine in shaping the biodiversity and structural dynamics of microbial communities. (umu.se)

Our study identified a novel mechanism maintaining Bacillus subtilis and Mycobacterium smegmatis biofilms-active production of calcite minerals. (nature.com)
Based on 16S rRNA gene sequencing, strain RMB7 was identified as Bacillus specie. (biomedcentral.com)

My research group aims to understand how biofilms develop and disperse and how they respond to environmental stresses including therapeutic compounds. (southampton.ac.uk)
My research group aims to understand biofilm infection microenvironments, with a focus on studying wound biofilms under host-relevant conditions. (tigs.res.in)

As the biofilm matures, it grows into a complex three-dimensional structure-with skyscraper-like structures. (nautil.us)

For the study, first author Matthew Powers, an undergraduate student in Shank's lab, used a strain of B. subtilis--a species commonly used in lab experiments--that fluoresces when genes for biofilm formation are being shut off. (sciencedaily.com)
[10] [11] A cell that switches to the biofilm mode of growth undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated . (wikipedia.org)

This can contribute to biofilm dispersal, and provides a mechanism for the release of extracellular DNA (eDNA) within biofilms. (southampton.ac.uk)

The metabolism of different bacterial species can be influenced by the interactions between the metabolites of different organisms. (ijbpr.net)
Biofilms are a mixture of complex communities of organisms mostly composed of diverse bacteria that vary depending on the surrounding environmental conditions induced by physical and chemical factors. (intechopen.com)
Biofilms can be found in a variety of habitats, on free‐living, on the surface of other organisms or inert surfaces, both in aquatic as well as terrestrial environments. (intechopen.com)

When one of the B. subtilis colonies fluoresced, he picked a close-lying, non-fluorescing colony off of that plate, regrew it, and then sequenced those cells, determining that the species was P. protegens. (sciencedaily.com)
To assess the possible roles of biomineralization in biofilm development, we grew wild-type B. subtilis cells on media in the presence or absence of calcium acetate as a calcium source. (nature.com)
For instance, the cells within a B. subtilis biofilm that are engaged in protease production are randomly determined. (the-scientist.com)

In ecology, biofilms contribute to nutrient cycling and biodegradation of organic matter. (scientiaen.com)
If viral latency is not nutrient energy-dependent and controlled by the physiology of reproduction in species from bacteria to humans, I will change my claims. (scentoferos.com)
Biofilms profoundly impact the environment, playing crucial roles in nutrient cycling, wastewater treatment, and even pathogen persistence. (nautil.us)
Further, biofilms possess distinct nutrient acquisition and protection mechanisms, contributing to their extended survival and persistence. (tigs.res.in)

Both of the bacteria from this study are associated with plant roots, and understanding their interactions using DAPG and other secreted compounds could be important for creating healthy microbial soil communities for plants to grow in, possibly boosting agricultural yields, said Shank. (sciencedaily.com)
The process of biofilm formation is influenced by a variety of factors, including environmental conditions, bacterial genetics, and microbial interactions. (scientiaen.com)
The interactions between cells and their surroundings are primarily responsible for the creation of biofilms. (ijbpr.net)
Through these interactions bacteria in the biofilm acquire biocide tolerance and resistance enabling them to endure in the presence of biocides. (ijbpr.net)
They can be found very early in Earth's fossil records (about 3.25 billion years ago) as both Archaea and Bacteria, and commonly protect prokaryotic cells by providing them with homeostasis, encouraging the development of complex interactions between the cells in the biofilm. (wikipedia.org)
These intriguing molecules, generated from L-amino acids by racemase enzymes, play diverse and specific roles in various cellular processes, including cell wall formation, biofilm stability, spore germination, and interbacterial interactions. (umu.se)

This species, however, unlike C. albicans, has been shown to readily develop stable resistance to fluconazole in vitro and in infected patients, strongly suggesting that C. dubliniensis possesses a readily inducible fluconazole resistance mechanism ( 11 - 13 ). (cdc.gov)
The calcite-dependent patterns provide resistance to environmental insults and increase the overall fitness of the microbial community. (nature.com)
Bacteria can develop antibiotic resistance through horizontal gene transfer within biofilms. (ijbpr.net)
Antibiotic resistance and biofilm formation are regulated by similar genetic mechanisms. (acs.org)
There aren't any compounds in the clinic that disarm antibiotic-resistance mechanisms, and there's nothing that targets the biofilm machinery," says medicinal chemist Robert W. Huigens of the University of Florida, who was not involved with the study. (acs.org)

This is important given that biofilms are nearly always found as mixed-species communities, consisting of diverse bacterial and fungal species existing in close proximity with each other. (tigs.res.in)

Biofilms are of great interest to the scientific community due to their impact on human health, ecology and industry. (scientiaen.com)
Biofilms play an important role in ecology and industry, as they are found in a variety of natural and man-made environments. (scientiaen.com)
The result shown that g-C 3 N 4 could significantly reduce the residue of TC in riverbed sediment, without affecting the microbial ecology in the environment. (researchsquare.com)

But sometimes the communities can become disrupted and imbalanced - this is called dysbiosis . (lactobacto.com)

Biofilms also interfere with industrial processes, for example, by clogging, or corroding pipes, and by instigating corrosion on ships' hulls. (sciencedaily.com)
These microbial processes allow exploration of novel applications, for example, the biosynthesis of metal nanomaterials. (wikipedia.org)
In contrast to chemical and physical methods, microbial processes for synthesizing nanomaterials can be achieved in aqueous phase under gentle and environmentally benign conditions. (wikipedia.org)
The biophysics of biofilm formation involves the interaction of physical forces, such as surface tension and hydrodynamics, with biological processes, such as bacterial adhesion and EPS production. (scientiaen.com)

A microbial biofilm is a community of adherent microbial cellular forms with properties that help protect the microbial community from disruption by physical, chemical, or immunological attack. (jmb.or.kr)

We isolated and named this phage, showed that it becomes superinfective to its host during biofilm development, and found that it plays a role in phenotypic diversification of biofilm bacteria. (southampton.ac.uk)

Background Host-associated microbial communities have important roles in tissue homeostasis and overall health. (researchgate.net)

In the context of biofilm formation, surface tension plays a key role in bacterial attachment to surfaces. (scientiaen.com)
Our results suggest that it is highly feasible that the formation of mineral scaffolds plays a cardinal and conserved role in bacterial multicellularity. (nature.com)

Biofilms may form on living (biotic) or non-living (abiotic) surfaces and can be prevalent in natural, industrial, and hospital settings. (wikipedia.org)
So far, a large component of biofilm research has used laboratory systems, such as polystyrene surfaces and protein broths, in an attempt to study biofilms and investigate treatment effects. (tigs.res.in)

The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single cells that may float or swim in a liquid medium. (wikipedia.org)

Bacteria select their place in the biofilm based on which microenvironments suit them best and which neighboring bacteria offer the most rewarding symbiotic relationships. (nautil.us)

Multiple different species of bacteria fill distinct niches in the microbial community and stay and leave in strategic and deliberate ways. (nautil.us)
Microbial forms living in biofilms are morphologically and functionally distinct from those of free-floating (planktonic) forms of the same species. (jmb.or.kr)

Indeed, microbial products have been reported to modulate the enterocyte barrier function and mucus structure ( Hooper and Macpherson, 2010 ). (frontiersin.org)
It turns out that we all (both healthy and sick) have biofilms living on the mucus lining of the sinuses. (lactobacto.com)

Oral biofilms are structured microbial communities consisting of a mixture of bacteria and fungi. (forsyth.org)

We compared oral and systemic isolates for the capacity to form biofilm in an in vitro biofilm model and pathogenicity in the Galleria mellonella infection model. (biomedcentral.com)

Nitric oxide-mediated regulation of biofilm dispersal. (southampton.ac.uk)
We discovered that exogenous nitric oxide can act as a signal for the dispersal of bacterial biofilms. (southampton.ac.uk)

Subpopulations of cells within the biofilm differentiate to perform various activities for motility, matrix production, and sporulation, supporting the overall success of the biofilm. (wikipedia.org)

Biofilms are also known to colonize medical devices and implants, leading to device failure and increased risk of infection. (scientiaen.com)

In this incident density sampled case control study of 189 children followed from 2-months to 5-years, we use the salivary bacteriome to 1) prospectively test the ecological hypothesis of ECC in salivary bacteriome communities and 2) identify co-occurring salivary bacterial communities predicting future ECC. (researchsquare.com)
Bacterial communities which assemble before 12-months of age can promote or inhibit an ecological succession to S. mutans dominance and cariogenesis. (researchsquare.com)
The bacterial communities' structure of the samples treated with TC, g-C 3 N 4 or TC/g-C 3 N 4 were distinguishable. (researchsquare.com)

For example, if the sinus microbial community becomes disrupted by an infection. (lactobacto.com)
While this has moved the field forward, a major concern is that these conditions poorly replicate the human host environment, and therefore may not faithfully mimic biofilms in infection states. (tigs.res.in)
Together, these microbial and host factors constitute the infection microenvironment, with specific biochemical and biophysical signatures. (tigs.res.in)
We study wound biofilms under host-relevant conditions, by developing biomimetic platforms that recapitulate the infection microenvironment. (tigs.res.in)

These components help to create a complex three-dimensional structure that provides the biofilm community with protection from environmental stresses and access to nutrients. (scientiaen.com)
Much like our human cities, biofilms in nature are complex, highly differentiated, and multicultural. (nautil.us)
A biofilm may also be considered a hydrogel , which is a complex polymer that contains many times its dry weight in water. (wikipedia.org)
In contrast to the free-living, or planktonic, bacteria commonly studied in the lab, most prokaryotes in nature settle down in complex communities, often consisting of several interacting species. (the-scientist.com)
Deze goede bacteriën vormen een complex netwerk en zouden slechte bacteriën kunnen onderdrukken. (scriptieprijs.be)

Early childhood caries (ECC) - dental caries (cavities) occurring in primary teeth up to age 6-years - is a prevalent childhood oral disease with a microbial etiology. (researchsquare.com)

BACKGROUND: While genome-resolved metagenomics has revolutionized our understanding of microbial and genetic diversity in environmental samples, assemblies of short-reads often result in incomplete and/or highly fragmented metagenome-assembled genomes (MAGs), hampering in-depth genomics. (bvsalud.org)

[2] [3] The cells within the biofilm produce the EPS components, which are typically a polymeric conglomeration of extracellular polysaccharides , proteins , lipids and DNA . (wikipedia.org)

DAPG also blocked spore formation. (sciencedaily.com)

Growth pattern of Mycobacterium species are different such as M. chelonae and M. fortuitum form biofilm as vertical and entire surface growth, respectively [ 93 ]. (biomedcentral.com)
Microbial biofilms form on liquid/solid interfaces in nature, such as rocks and clay particles and decaying plant materials. (jmb.or.kr)
[8] Biofilms can form on the teeth of most animals as dental plaque , where they may cause tooth decay and gum disease . (wikipedia.org)
Biofilms form when groups of bacteria cover themselves in a sticky mixture of sugars, protein, and DNA. (the-scientist.com)

Biofilms are increasingly recognised as the predominant mode of bacterial growth including within medical, engineered, and environmental contexts. (southampton.ac.uk)
20 generations, a few days of biofilm growth) within biofilms. (southampton.ac.uk)
Flow rates and turbulence can impact the concentration of nutrients and oxygen in the biofilm matrix, which can affect bacterial growth and EPS production. (scientiaen.com)
Cell growth is encouraged by biofilm, which also shields them from many forms of environmental stress. (ijbpr.net)
A unique three-dimensional self-produced matrix that provides greater food supplies and supports enhanced growth and survival against biocides holds this community of bacteria together. (ijbpr.net)
Under TC stress, g-C 3 N 4 slowed down the growth of Cyanobacteria to some extent and restored the changes of bacterial community structure caused by TC, and reduced the residual TC in water body, thus eliminating the side effects of TC. (researchsquare.com)

A community of practice (CoP) was established by the Centre for Social Development in Africa to promote collaboration between the sectors and to assist communities in their environments. (bvsalud.org)

The character of biofilm communities of denture wearers, however, has been shown to be distinctive when compared with healthy non-denture-wearing individuals. (medscape.com)

On silicone pads, C. albicans and C. dubliniensis produced more biofilm (1.12 to 6.61 mg) than the other species (0.25 to 3.66 mg). (biomedcentral.com)

Glycopeptidolipids are indispensable for initial surface attachment during biofilm formation in Mycobacterium smegmatis [ 111 ]. (biomedcentral.com)

Anatomy6

Organisms48

Diseases1

Chemicals and Drugs40

Analytical, Diagnostic and Therapeutic Techniques and Equipment28

Psychiatry and Psychology6

Phenomena and Processes64

Disciplines and Occupations16

Anthropology, Education, Sociology and Social Phenomena5

Technology, Industry, Agriculture5

Information Science8

Named Groups3

Health Care72

Geographicals11

Microorganisms14

Known as biofilms3

Microbes12

Staphylococcus3

Antibiotics7

Strains8

Maturation2

Quorum6

Presence of candidal organisms2

Infections14

Candida11

Oral microbial community1

Extracellular polymeric3

Persistent1

Catheters2

Pseudomonas4

Antimicrobial4

Disrupt2

Microbiome5

Virulence3

Multicellular communities1

Bacterium4

Metabolic6

Several microbial2

Pathogens1

Functional3

Structural2

Bacillus2

Research group aims to understand2

Matures1

Genes2

Release of extracellular1

Organisms3

Subtilis3

Nutrient4

Interactions6

Resistance5

Fungal1

Ecology3

Dysbiosis1

Processes4

Adherent1

Phenotypic1

Roles1

Role in bacterial2

Surfaces2

Planktonic cells1

Microenvironments1

Distinct2

Mucus2

Bacteria and fungi1

Vitro1

Dispersal2

Subpopulations1

Medical devices and implants1

Bacterial communities3

Infection4

Complex5

Etiology1

Genetic1

Proteins1

Spore1

Form4

Growth6

Centre1

Denture1

Dubliniensis1

Mycobacterium1