Species cephalosporin resistance. Medical search. Frequent questions

The data suggest that the mucoid phenotype could be associated with extrachromsomal element(s) carrying resistance genes to antibiotics and that these extrachromosomal elements may not harbour resistance determinants to chloramphenicol. (scirp.org)
We have a high-performance medicine in which we have to use antibiotics over and over again, and so resistance will carry on developing. (medscape.com)
In 2021, the number of reported cases of Acinetobacter species [infections], which are resistant to various classes of antibiotics, was almost twice as high (plus 121%) as the average from 2018 to 2019," reported the ECDC. (medscape.com)
The most important measure to avoid antibiotic resistance is to use antibiotics as sparingly as possible. (medscape.com)
The prevalence of bacterial strains and their resistance to antibiotics in urine samples from cats in the UK have not been widely reported previously. (bvna.org.uk)
Notably, Enterococcus species were frequently found to be resistant to multiple antibiotics, and several other isolates demonstrated resistance to frequently used antibiotics. (bvna.org.uk)
The inappropriate use of antibiotics for bacterial cystitis could not only be ineffective to manage bacterial cystitis in cats but promote further antimicrobial resistance. (bvna.org.uk)
Even though feline lower urinary tract disease is one of the most common reasons for vets to prescribe antibiotics, the prevalence of bacterial strains in the urine of cats with this condition, and their resistance to commonly used antibiotics, had not been widely studied in the UK to date. (bvna.org.uk)
The resistance of these newly discovered bacteria to antibiotics is a concern, as this would make the treatment of life-threatening infections more difficult. (facmedicine.com)
Both new species are resistant to penicillin and cephalosporin group antibiotics. (facmedicine.com)
ESBL enzymes create resistance within the body to most beta-lactam antibiotics, including penicillins, cephalosporins, and aztreonam. (birmingham.ac.uk)
Ureido-penicillins, cephalosporins, aminoglycosides, imipenem, trimethoprim-sulfamethoxazole are the drugs of choice to treat P. vulgaris associate infections but it possess high level of resistance against penicillin and other antibiotics[4]. (slideserve.com)
We believe it is: in the words of the House of Lords' report, "Resistance to antibiotics … constitutes a major threat to public health and ought to be recognised as such more widely than it is at present. (bmj.com)
Other aspects of appropriate therapy that deserve attention include a shift to more 'resistance'-proof antibiotics in empiric therapy, which may be accompanied by better outcomes. (karger.com)
Between 2007 and 2017, strains of escherichia coli (particularly implicated in food poisoning) and klebsiella pneumoniae (lung infections) became increasingly resistant to third-generation cephalosporin antibiotics. (europeandatajournalism.eu)
Cephalosporins are beta-lactam antibiotics that are used to treat gram-positive and gram-negative bacterial infections. (starhealth.in)
In Enterobacterales , the prime antimicrobial resistance mechanism against β-lactam antibiotics is mainly the production of β-lactamases, particularly extended-spectrum β-lactamases (ESBLs). (frontiersin.org)
The free access of antibiotics from pharmacy without prescription, lack of antibiotic policy and dedicated laboratory for susceptibility testing and surveillance is leading to distressing public health threat of antibiotic resistance in Nepal. (biomedcentral.com)
Investigations have shown that ESBL enzymes also confer resistance to other classes of antibiotics (Fashae et al . (scialert.net)
The E. coli isolate from the patient was also resistant to antibiotics in at least five additional antibiotic classes, including cephalosporins, fluoroquinolones, sulfonamides, aminoglycosides, and tetracyclines. (cdc.gov)
Aim: The aim was to study the frequency and distribution of uropathogens and their resistance pattern to antibiotics in a tertiary care hospital. (jbclinpharm.org)
This quarter's Featured Article reminds us that not only cats and dogs require prudent use of antibiotics, as the authors studying antibiotic resistance in 398 pet reptiles found. (bsava.com)
Acinetobacter species cause infections that are difficult to control due to multi-drug resistance and are noted for their intrinsic resistance to antibiotics and for their ability to acquire genes encoding resistance for the production of beta-lactamases and Aminoglycoside-modifying enzymes. (microbiologyjournal.org)
5,6 Additional risk factors include prolonged stay in a hospital or healthcare facility, presence of invasive devices such as bladder catheters, and exposure to certain antibiotics, such as vancomycin, third-generation cephalosporins, and antianaerobic agents. (uspharmacist.com)
Enterococci impart resistance to antibiotics in a variety of ways. (uspharmacist.com)
Antimicrobial resistance (AMR) occurs when microorganisms fail to respond to the therapeutic onslaught of antibiotics. (eijppr.com)
In more than 30% of infections, the isolate will be resistant to one or more clinically useful antibiotics (CDC, Antibiotic Resistance Threat Report , 2019. (pids.org)
While Streptococcus pyogenes remains highly susceptible to beta-lactam antibiotics, over the past decade increasing prevalence of clindamycin and macrolide resistance are being reported worldwide. (pids.org)
The increase in multidrug resistance of antibiotics in recent decades has been associated with its misuse, resulting in an increased rate of morbidity and mortality, prolonged hospital stays and increased care costs. (bcan.org)
Specifically, resistance to fluoroquinolones has increased its prevalence, a group of antibiotics widely used in urology. (bcan.org)

The antimicrobials most commonly indicated in Enterobacter infections include carbapenems, fourth-generation cephalosporins, aminoglycosides, fluoroquinolones, and TMP-SMZ. (medscape.com)
Carbapenem-resistant Klebsiella pneumoniae makes up under 1%, and E coli with a combined resistance against third-generation cephalosporins, fluoroquinolones, and aminoglycosides is around 3%, following a decline in the last 3-4 years. (medscape.com)
Acinetobacter species with a combined resistance against fluoroquinolones, aminoglycosides, and carbapenems make up 4% of the total in Germany. (medscape.com)
Serious concurrent conditions and prior use of fluoroquinolones, carbapenems, or broad-spectrum cephalosporins have been independently associated with acquisition of infections caused by CRE. (cdc.gov)
The increasing resistance problems of recent years are probably related to the use of increasingly broad spectrum agents (cephalosporins and fluoroquinolones) and crowding of the most vulnerable members of society in day care centres and nursing homes. (bmj.com)
ESBL-producing Enterobacterales from the GCC region show high levels of resistance to ampicillin, aztreonam, third-/fourth-generation cephalosporins, fluoroquinolones, and trimethoprim-sulfamethoxazole. (frontiersin.org)

Proteus species were highly resistant to ampicillin, Ceftazidime, Aminoglycosides and Quinolones showing 70% of multiple drug resistant (MDR) and 3.4% Pan drug resistant (PDR) of which 24% of Proteus isolates were confirmed ESBL producers. (ijcmas.com)
2003) suggested the use of aminoglycosides, floroquinolones and cabapenems in preference to cephalosporins in the treatment of ESBL infections. (scialert.net)
2004). Recent studies have shown however, that ESBL producing organisms have started developing resistance to the aminoglycosides and floroquinolones, thus posing serious therapeutic consequences. (scialert.net)

Approximately 3.2% of Enterobacteriaceae reported in healthcare-associated infections were resistant to carbapenems and 26.9% were resistant to cephalosporins. (cdc.gov)
Carbapenems continue to have the best activity against E cloacae, E aerogenes, (now known as Klebsiella aerogenes ) and other Enterobacter species. (medscape.com)
If you take the K pneumoniae resistance to carbapenems, for example, which is under 1% in Germany, then this is actually comparable in almost every country in northwest Europe," said Eckmanns. (medscape.com)
Carbapenemases are a class of enzymes that can confer resistance to carbapenems and other Beta-lactam antibiotic drugs, but not all carbapenemase-producing isolates are carbapenem-resistant. (cdc.gov)
There is not enough data to compare carbapenems with specific cephalosporins to conclude that these are the most appropriate agents. (karger.com)
ESBLs are beta-lactamases capable of conferring bacterial resistance to the penicillins, first-, second-, and third-generation cephalosporins, and aztreonam except the cephamycins or carbapenems with various genotypes such as CTX-M, TEM, SHV, OXA [ 16 ]. (biomedcentral.com)
The ESBL- and AmpC-positive bacteria showed significant levels of reduced susceptibility to the carbapenems and cephalosporins. (eijppr.com)
La resistència a carbapenems ha estat pràcticament nul·la en totes les espècies estudiades. (uab.cat)
bla IMI is a carbapenemase gene mediating resistance to carbapenems but has not been commonly found. (medscape.com)
Strain WCHECl-1060 belongs to a new sequence type, ST410, and was resistant to carbapenems and colistin but was susceptible to third-generation cephalosporins. (medscape.com)

Additionally, other Enterobacterales had resistance against cephalosporins and penicillins. (bvna.org.uk)
Long-term antimicrobial treatments have undoubtedly influenced the evolution of resistant strains, with the majority of bacteria in this study exhibiting resistance against the majority of commonly used antibiotic combinations, including penicillins, cephalosporins, macrolides and tetracyclines. (bsava.com)
Among the clinical populations of Gram-negative microorganisms, bla TEM-1 is the most frequently detected antimicrobial resistance gene and, although its expression results in penicillin resistance, diverse point mutations in the bla TEM-1 gene have contributed to the emergence of TEM-type extended-spectrum β-lactamases (ESBLs), resulting in simultaneous resistance to penicillins and broad-spectrum cephalosporins (8). (scielo.br)
History of a serious hypersensitivity reaction (e.g., anaphylaxis or Stevens-Johnson syndrome) to amoxicillin and clavulanate potassium or to other beta-lactams (e.g., penicillins or cephalosporins). (nih.gov)

Umar, U. , Anagor, S. , Aliyu, A. and Suleiman, A. (2016) Hypermucoviscosity in Clinical Isolates of Klebsiella pneumoniae Correlates with High Multiple Antibiotic Resistance (MAR) Index. (scirp.org)
Wild raptor isolates showed similar patterns of antimicrobial resistance when compared with isolates recovered from the captive raptor controls. (vin.com)
While the Enterococcus isolates were uniformly susceptible to Beta lactams, they were innately resistant to cephalosporins. (vin.com)
Enterobacterales isolates that are concomitant ESBL producers and are carbapenem resistant have been increasingly reported and demonstrate alarmingly increased antibiotic resistance patterns compared with ESBL Enterobacterales . (frontiersin.org)
Multidrug resistance was found among 13(86%) of the isolates. (biomedcentral.com)
Test isolates showing resistance to any of the 2nd and 3rd generation cephalosporins were subjected to double disc synergy test studies. (scialert.net)
Number of non-Typhi Salmonella species isolates that are resistant to third-generation cephalosporins. (cdc.gov)
Salmonella species isolates from humans, as opposed to all Salmonella species isolates. (cdc.gov)
Although, almost all previous studies and efforts to control the dissemination of these genes have been based on isolates from clinical samples, antibiotic resistance genes can also occur in nonpathogenic bacteria, which can then be transferred via lateral gene transfer (6). (scielo.br)
Isolates of 13.3% of C. freundii and 16.7% of E. cloacae resistant to ceftazidime (13.3, 16.7% resistance respectibility) remained susceptible to cefepime and imipenem/cilastatin. (elsevierpure.com)
To analyze the antibiotic resistance patterns among Acinetobacter isolates and to detect Carbapenemase and MBL among MDR Acinetobacter isolates. (microbiologyjournal.org)
AmpC was phenotypically detected in E. coli (3%), Klebsiella species (2%), and P. aeruginosa isolates (1%) for samples from poultry milieus. (eijppr.com)
40,000 S. aureus isolates identified from inpatient and outpatient settings in a large children's hospital demonstrated resistance to clindamycin and TMP-SMX increased among outpatient isolates between 2005-2014. (pids.org)
Microbiological laboratories should be aware of the unusual carbapenem-resistant but third-generation cephalosporin-susceptible profiles of these IMI-producing isolates. (medscape.com)

In August 2017, meropenem/vaborbactam (Vabomere) was approved for complicated urinary tract infections (cUTIs), including pyelonephritis, caused by susceptible Enterobacteriaceae: E coli, K pneumoniae, and E cloacae species complex. (medscape.com)
First-generation and second-generation cephalosporins are inactive against Enterobacter infections. (medscape.com)
Third-generation cephalosporins are not indicated for the treatment of severe Enterobacter infections, perhaps with the notable exception of uncomplicated infections. (medscape.com)
RÉSUMÉ La présente étude visait à estimer la prévalence et les facteurs de risque des infections liées aux procédures de soins dans tous les hôpitaux de la région du centre-est de la Tunisie, comptant neuf établissements, en 2005. (who.int)
Nous en concluons que les infections liées aux procédures de soins constituent un motif de préoccupation dans cette région de Tunisie. (who.int)
Each year, more than 35,000 people die because of antibiotic-resistant infections, with more than 2.8 million infections occurring in the United States, according to CDC's Antibiotic Resistance Threats Report . (cdc.gov)
To better understand the financial burden these infections place on health care, CDC teamed up with experts at the University of Utah School of Medicine and released estimates external icon that treating six alarming antibiotic resistance threats identified by CDC contribute to more than $4.6 billion in health care costs annually. (cdc.gov)
They then multiplied the pathogen-specific cost data by national infection case counts, previously published in the 2019 Antibiotic Resistance Threats Report and Multidrug-Resistant Bacterial Infections in U.S. Hospitalized Patients, 2012-2017 external icon to find the estimated total healthcare costs to treat these infections. (cdc.gov)
A long-lasting effort is necessary to keep the [antibiotic-resistance] situation at a good level," said Tim Eckmanns, MD, head of the Department for Nosocomial Infections, Surveillance of Antibiotic Resistance and Usage at the Robert Koch Institute (RKI) in Berlin, Germany. (medscape.com)
The ECDC data show that from 2016 to 2020, the number of infections and deaths due to almost all antibiotic resistances had increased. (medscape.com)
The general university hospital PJI incidence rate was 1.43%, with 5.3% of infections from Gram-negative species. (hindawi.com)
The remaining primary skin infections of nocardiosis manifest as pustules, abscesses, or cellulitis and often mimic disease caused by more common organisms, such as Staphylococcus species. (medscape.com)
Since Nocardia species infections are very often sporadic, information from randomized clinical trials comparing the clinical efficacy of specific antimicrobial agents is lacking. (antimicrobe.org)
Different Proteus species are commonly implicated pathogens in hospital as well as community acquired infections. (ijcmas.com)
They target bacterial species and effectively treat infections. (starhealth.in)
Cephalosporins are used to treat skin infections, meningitis and other bacterial-resistant infections. (starhealth.in)
Infections secondary to these pathogens are widely common but multidrug resistance (MDR) in Enterobacterales has become a significant challenge with increased morbidity, mortality, and cost of management. (frontiersin.org)
In this report, we aim to describe the epidemiology of extended-spectrum cephalosporin-resistant (ESC-R) and carbapenem-resistant (CR) Enterobacteriaceae infections in children. (elsevierpure.com)
At least four Leuconostoc species (including Leuconostoc mesenteroides, Leuconostoc paramesenteroides, Leuconostoc cremoris , and Leuconostoc citreum ) may cause human infections. (oncohemakey.com)
Risk factors for serious infections caused by Lactobacillus species include underlying immunocompromised state (including human immunodeficiency virus [HIV] disease) and gastrointestinal surgery. (oncohemakey.com)
For example, the Mycoplasma species, which cause a range of infections in different animal species, lack a cell wall. (futurelearn.com)
These species cause infections that are difficult to control due to multi-drug resistance. (microbiologyjournal.org)
Enterococcus species are a leading cause of hospital-acquired infections and the second most common nosocomial bloodstream pathogen in the United States. (uspharmacist.com)
Infections with Klebsiella , Enterobacter , and Serratia are often hospital-acquired and occur mainly in patients with diminished resistance. (msdmanuals.com)
Carbapenemase-producing species of K. pneumoniae (KPC) have been isolated internationally as well as in the US, making treatment of some infections very problematic. (msdmanuals.com)
Recent estimates of the burden of antimicrobial resistance suggest that there are approximately 700,000 deaths worldwide every year due to infections with antimicrobial resistant bacteria, with nearly 50,000 of these deaths occurring in the United States and Europe (CDC. (pids.org)
Antibiotic treatment for a single outpatient infection has been shown to influence resistance patterns of future infections. (pids.org)

Good susceptibility was seen with imipenem and cephalosporins. (jbclinpharm.org)
Imipenem and fourth-generation cephalosporin were stable to β-lactamase produced from these species. (elsevierpure.com)

These species were validated primarily on the basis of DNA-DNA hybridization, 16S rRNA gene sequence analysis, antimicrobial susceptibility and biochemical profiles, and, to a lesser degree, on high-performance liquid chromatography ( 22 , 54 , 55 , 69 ). (antimicrobe.org)
If tetracycline resistance is associated with resistance to other antimicrobials in a range of bacterial species, then doxycycline PEP could have the unintended effect of selecting for resistance to other antimicrobials in these bacterial species.METHODS: Antimicrobial susceptibility data were retrieved from two sources: pubMLST (https://pubmlst.org/) and Pathogenwatch (https://pathogen.watch/) for the following bacterial pathogens: Klebsiella pneumoniae, Salmonella enterica subsp. (itg.be)
This study was conducted to determine the distribution of species and antibiotic susceptibility pattern of Shigella species isolated from stool specimen among children less than 5 years of age in Nepal. (biomedcentral.com)
2003). The extensive use of oxyimino-cephalosporins in medical institutions has resulted in diminished susceptibility of some enterobacteriaceae. (scialert.net)
Susceptibility to the cephalosporins, quinolones, and trimethoprim-sulfamethoxazole (TMP-SMX) is variable. (oncohemakey.com)
In the case of penicillin allergy or resistance, therapy should be based on results of susceptibility testing. (oncohemakey.com)

These germs include: Vancomycin-resistant Enterococcus , Carbapenem-resistant Acinetobacter species , Methicillin-resistant Staphylococcus aureus , Carbapenem-resistant Enterobacterales, Extended-spectrum cephalosporin resistance in Enterobacterales suggestive of extended-spectrum β-lactamase (ESBL) production, and Multidrug-resistant Pseudomonas aeruginosa . (cdc.gov)
All but one participant acquired multiple strains of bacteria with 83 unique strains identified (53 E. coli, 10 Klebsiella, 20 other ESBL-GN species) and some of these strains being shared by as many as four subjects. (birmingham.ac.uk)
Proteus,multiple drug resistance,Cephalosporin ESBL. (ijcmas.com)
The emergence and spread of ESBL-producing Enterobacteriaceae in intensive care units (ICU) is said to be due to clonal dissemination of a few epidemic strains as well as horizontal transmission of resistance gene-carrying plasmids among bacterial organisms (Wu et al . (scialert.net)
2008). The resistance is probably because of the presence of extended-spectrum beta-lactamase (ESBL) enzyme that was derived from the wide spread TEM-1/2 and SHV-1 family. (scialert.net)
ESBL was phenotypically detected in E. coli , Klebsiella species, and P. aeruginosa for samples from poultry at the rate of 4%, 1%, and 2% while samples from livestock milieus had ESBL-positive bacteria at the rate of 5%, 2%, 4% for E. coli , Klebsiella species and P. aeruginosa respectively. (eijppr.com)
PCR detected CTX-M-15 genes (20%) and FOX-1 genes (25%) which mediated ESBL and AmpC resistance in bacteria. (eijppr.com)

We applied CDC definitions to identify antimicrobial-resistant phenotypes among Enterobacteriaceae , including Escherichia coli , Klebsiella species, and Enterobacter species, reported in CLABSI, SSI, and CAUTI by general acute-care hospitals in California ( 3 ). (cdc.gov)
Thus, these drugs are active against Escherichia coli and Klebsiella and Proteus species (though several strains of these organisms have developed resistance). (britannica.com)
In humans K. pneumoniae is an important species of medical importance of the genus Klebsiella and is found as saprophyte in the nasopharynx and in the gastrointestinal tract. (scirp.org)
Some encapsulated Klebsiella species form glistening mucoid colonies of viscid consistency. (scirp.org)
Most reports to date have identified the mcr-1 gene in E. coli , but it has also been reported from Salmonella species, Shigella sonnei , and Klebsiella pneumoniae . (cdc.gov)
A further example is innate production of enzymes that can inactivate a drug, such as Klebsiella species and ampicillin resistance. (futurelearn.com)
Els estudis de sensibilitat en Escherichia coli i Klebsiella pneumoniae mostren un clar increment de la resistència a cefalosporines de tercera generació (C3G) i aztreonam, fruit d'una major prevalença de soques portadores de BLEA i pAMPCt. (uab.cat)
En Klebsiella oxytoca el principal mecanisme implicat és la hiperproducció de llur β-lactamasa cromosòmica que confereix resistència a l'aztreonam. (uab.cat)
Some of the most worrisome antibiotic-resistant bacteria are MDR Enterobacterales , which includes species like E. coli and Klebsiella pneumoniae . (pids.org)

The proportion of cephalosporin-resistant Escherichia coli increased 7% (risk ratio 1.07, 95% CI 1.04-1.11) per year during 2014-2017. (cdc.gov)
This resistance has spread to strains of E. coli and other gram-negative bacteria (Iroha et al . (scialert.net)
The epidemiology of ESC-R and CR Enterobacteriaceae varied according to hospital and species (E coli vs K pneumoniae). (elsevierpure.com)
Bei den E. coli-Stämmen wurden ähnliche Resistenzquoten gegenüber Ampicillin (8,9 %) und dem Cephalosporin der ersten Generation (8,4 %) gemessen. (fu-berlin.de)

The fifth-generation cephalosporins are found to be developed in the lab to specifically target resistant strains of bacteria. (bharatbook.com)
Whether these phenotype and resistances that had no fitness cost to the bacterium could significantly affect the virulence of the bacteria in vivo remains to be investigated. (scirp.org)
have been implicated as indicator bacteria species for the detection of antimicrobial resistance. (vin.com)
Nocardiosis is an infection caused by several species of soil-borne aerobic bacteria belonging to the genus Nocardia . (medscape.com)
Two new species of bacteria have been found in the blood of patients in China. (facmedicine.com)
The therapeutic use of bacteriophages, viruses that infect and kill bacteria, is well suited to be part of the multidimensional strategies to combat antibiotic resistance. (asm.org)
4 Bacteria have evolved very sophisticated means of exchanging DNA, both within their own genus and species and across them. (bmj.com)
and to what extent will this affect antibiotic resistance in different bacteria? (bmj.com)
One area where data are not conclusive concerns the treatment of enteric bacteria carrying extended spectrum betalactamases, where the only cephalosporin of concern is ceftazidime. (karger.com)
At issue: the natural ability of bacteria to develop resistance to such treatments. (europeandatajournalism.eu)
Third-generation cephalosporins are less effective in most gram-positive bacteria but are effective against Enterobacteriaceae, Neisseria spp. (starhealth.in)
Bacteria with this resistance mechanism have now been identified from humans, food, environmental samples, and food animals in at least 20 countries around the world. (cdc.gov)
The presence of the mcr-1 gene on a plasmid means that colistin resistance can be shared with other more resistant bacteria such as CRE, raising the possibility that untreatable bacteria could develop. (cdc.gov)
CDC's National Antimicrobial Resistance Monitoring System, in collaboration with the Food and Drug Administration (FDA) and the U.S. Department of Agriculture (USDA), will continue to look for mcr-1 mediated colistin resistance in enteric bacteria from humans, retail meat, and food animals. (cdc.gov)
The rapid emergence of antibiotic resistance among bacteria is, to a great extent, due to the dissemination of antibiotic resistance genes by horizontal transfer mediated by plasmids, transposons and integrons (5). (scielo.br)
No difference in the antibacterial activity of cefepime to most species of bacteria was seen between this study and that 10 years ago. (elsevierpure.com)
Antimicrobial resistance can be intrinsic or acquired by bacteria. (futurelearn.com)
it is arguably more difficult to predict a resistance pattern when resistance is acquired by a bacteria. (futurelearn.com)
Of more concern is resistance acquired via a mobile genetic element (e.g. plasmids), as in this case multiple antibiotic resistance genes maybe present on the same element, rendering the bacteria resistant to multiple classes of drug. (futurelearn.com)
Resistance can develop due to mutations, or by bacteria acquiring new genetic material encoding resistance. (futurelearn.com)
Antimicrobial resistance is a natural process but the abuse and misuse of antimicrobial agents has favored the selection of mutants, the acquisition of resistance and the overgrowth of bacteria intrinsically resistant to these drugs. (uab.cat)
β-lactams (as cephalosporins) are one of the most widely used agents in clinical practice and their main mechanism of resistance by the bacteria is the production of enzymes known as β-lactamases. (uab.cat)

Extended-spectrum cephalosporin-resistant (ESCR) Enterobacteriaceae were resistant to ceftriaxone, ceftazidime, cefepime, or cefotaxime. (cdc.gov)
Carbapenem-resistant strains have emerged among species belonging to the Enterobacteriaceae family. (cdc.gov)
Carbapenem resistance among the Enterobacteriaceae is a serious healthcare challenge. (medscape.com)
The trend of colistin resistance among the Enterobacteriaceae should be also monitored. (medscape.com)

The second-generation cephalosporins (cefamandole, cefaclor, cefotetan, cefoxitin, and cefuroxime) have an extended antibacterial spectrum that includes greater activity against additional species of gram-negative rods. (britannica.com)
Second-generation cephalosporins have proven effective against gonorrhea, Haemophilus influenzae, and the abscesses caused by Bacteroides fragilis . (britannica.com)
Second-generation cephalosporins are effective against influenza and Bacteroides species. (starhealth.in)

Cross resistance was found in 4 of 5 antimicrobials for K. pneumoniae, 1 of 2 for C. jejuni, 3 of 5 for S. enterica subsp. (itg.be)
These associations include a higher prevalence of methicillin resistance in tetracycline resistant S. aureus, penicillin resistance in S. pneumoniae, macrolide and clindamycin resistance in S. pyogenes, fluoroquinolone resistance in S. enterica subsp. (itg.be)
Enterica serovar Typhi and third-generation cephalosporin resistance in K. pneumoniae. (itg.be)

The Multiple Antibiotic Resistance (MAR) index shows the themucoid strains with a high MAR index range of 0.7 - 1.0 with a median MAR index of 0.8, while the non-mucoid strains had a MAR index of 0.2 - 0.8 with a median MAR index of 0.35. (scirp.org)
Furthermore, the extrachromosomal elements bearing the mucoid phenotype and the resistance elements in the mucoid strains do not significantly impact on the fitness of the cognate strain. (scirp.org)
These two strains were found in both captive and wild raptor species. (vin.com)
The descriptive study of all phenotypically identified strains and multidrug-resistant strains of Acinetobacter species was conducted. (microbiologyjournal.org)
Of 6355 samples processed, 303 were found to be Acinetobacter species, among those 50 were multidrug-resistant strains. (microbiologyjournal.org)

The escalating global prevalence of MDR in Enterobacterales has led to limited treatment options, raising an urgent need for novel antimicrobial therapy(s) and detailed studies exploring underlying resistance mechanisms. (frontiersin.org)

cefuroxime and cefamandole) and third-generation ones (such as ceftazidime) tend to be more effective against gram-negative bacterial species that are resistant to the first-generation cephalosporins. (britannica.com)

Cefepime, a fourth-generation cephalosporin from the β-Lactam antibiotic class. (wikipedia.org)
Cefepime thus has a low rate of selection in drug resistance because it has potent antibacterial activity and is stable to β-lactamase. (elsevierpure.com)

8 ). DTR included an intermediate or resistant result to all reported agents within carbapenem, cephalosporin, and fluoroquinolone categories, as well as piperacillin-tazobactam and aztreonam when results were available. (cdc.gov)

We are currently observing increases in certain resistances in eastern Europe, which also commonly have a fatal outcome," he added. (medscape.com)
Cephalosporins are commonly used as antibiotic prophylaxis given their bactericidal activity against Gram-positive and Gram-negative organisms [ 9 ]. (hindawi.com)
recent data has indeed shown that the cephalosporin cefovecin is a commonly prescribed antibiotic [iii] for cats presenting with lower urinary tract disease. (bvna.org.uk)
Resistance was less commonly reported for chloramphenicol, sulfonamides, and quinolones. (bsava.com)

Empirical treatment with neuraminidase inhibitors and the combination of cephalosporins and macrolides or quinolones are suggested to be an effective treatment for COVID-19. (bharatbook.com)
Also, the cephalosporins in combinations with macrolides and quinolones may be potentially effective against COVID-19 (SARS-CoV-2). (bharatbook.com)

However, the nearest homolog genus-species was found to be Proteus hauseri. (slideserve.com)
Biofield treatment has been known as an alternative approach that may be useful to alter the resistance pattern in Proteus infected patients. (slideserve.com)
En Proteus mirabilis, s'ha pogut observat al llarg dels deu anys un lleuger increment de la resistència a l'associació amoxicil·lina-àcid clavulànic i de manera puntual l'aparició de soques productores de pAmpCt (tres soques amb CMY-2) o de BLEA (una soca amb CTX-M-1). (uab.cat)

Third-generation cephalosporins frequently show good in vitro activity against these organisms, but, as explained above, a significant risk of developing full resistance during therapy exists. (medscape.com)
Similar to anaerobic organisms of the genus Actinomyces , Nocardia species often form thin filaments that can resemble but are much thinner than those of true fungi (1-2 µm vs 3-5 µm in diameter). (medscape.com)
As antimicrobial resistance continues to rise globally, multidrug-resistant (MDR) organisms have posed a significant challenge for clinicians, owing to the dearth of effective therapeutic options to combat them. (uspharmacist.com)

This study sought to understand the prevalence of bacterial species isolated from 2,712 urine samples collected via cystocentesis from UK cats. (bvna.org.uk)

Although some species are inherently resistant to vancomycin, they are far less common than species that acquire resistance through transfer of genetic material. (uspharmacist.com)
Plasmid-mediated gene complexes confer high-level resistance to vancomycin and are often used as targets for molecular detection of VRE. (uspharmacist.com)
Eine Unempfindlichkeit gegenüber den Wirkstoffkombinationen Amoxicillin/Clavulansäure und Trimethoprim/Sulfamethoxazol sowie gegenüber dem Cephalosporin der ersten Generation und den Glycopeptiden (Vancomycin) wurde nicht nachgewiesen. (fu-berlin.de)

These findings have led to the identification of key functional genes that cause bacterial resistance in southeast Nigeria, and focus attention on the importance of surveillance and monitoring to mitigate the transmission of AMR in the environment, as antibiotic therapy could be affected. (eijppr.com)
Antimicrobial resistance occurs through different mechanisms, which include spontaneous (natural) genetic mutations and horizontal transfer of resistant genes through deoxyribonucleic acid (DNA). (who.int)
This report presents the status of AMR in Africa by analysing the main types of resistance and the underlying genes where possible. (who.int)

Leuconostoc species are catalase-negative, gram-positive coccobacilli that have been increasingly recognized as human pathogens over the last decade. (oncohemakey.com)
Acinetobacter species are increasingly important nosocomial pathogens and are capable of rapid adaptation to the hospital environment. (microbiologyjournal.org)
The objective of the current ering new classes of antimicrobials and the increasing study was, therefore, to assess the bacteriologic pro- emergence and reemergence of resistant pathogens, file, resistance pattern, and patient's outcome in Lan- mortality from infectious disease is increasing [1]. (who.int)

Die Einordnung der ermittelten MHK in die Kategorien sensibel beziehungsweise resistent erfolgte anhand von Grenzwerten aus den Normen des NCCLS und des Danish Integrated Antimicrobial Resistance Monitoring and Research Programme (DANMAP). (fu-berlin.de)

However, the increase of multidrug resistance along with emergence of extended-spectrum β-lactamase and ciprofloxacin resistance among Shigella spp. (biomedcentral.com)

Ceftobiprole has antipseudomonal characteristics that appear to be less susceptible to the development of resistance. (bharatbook.com)

If tetracycline resistance is associated with resistance to other antimicrobials in a range of bacterial species, then doxycycline PEP could have the unintended effect of selecting for resistance to other antimicrobials in these bacterial species. (itg.be)
We assessed if tetracycline resistance was associated with resistance to six relevant antimicrobials. (itg.be)
RESULTS: We found evidence of cross resistance to various antimicrobials in all six bacterial species assessed. (itg.be)
CONCLUSION: These results suggest that studies evaluating the effects of doxycycline PEP should include the effects of doxycycline on resistance not only to doxycycline but also to other antimicrobials and in a broader array of bacterial species than has been included in doxycycline PEP studies thus far. (itg.be)

The fourth-generation cephalosporins are effective against the same species as the third-generation cephalosporins. (starhealth.in)
Third-generation cephalosporin-resistant S. flexneri isolate was first reported from a stool sample of a 16-month old child in Paris in 1995 [ 7 ]. (biomedcentral.com)

For an interesting case study on Campylobacter species, fluoroquinolone resistance and poultry, please see the document in the see also section below. (futurelearn.com)

The increasing number of clinical trials for R&D of cephalosporin drugs is also expected to propel the growth of the cephalosporin drugs market over the forecast period. (bharatbook.com)
This species is the second most frequent nonfermenter encountered in clinical laboratories but with only about 1/10th the frequency of Pseudomonas aeruginosa 2 . (microbiologyjournal.org)
Under this premise, a randomized clinical trial is proposed to analyze the current panorama of UTI as a transcendent postoperative complication of TURB, under the context of the new emerging resistance parameters. (bcan.org)

And for methicillin-resistant Staphylococcus aureus (MRSA), 10 years ago we said we had 20%-25% resistance, but today it is significantly below 10%," said Eckmanns. (medscape.com)

Cephalosporins and enterococci. (futurelearn.com)

However, the bacterial species have developed a resistance to tetracyclines, according to data published in an NCBI article. (starhealth.in)

There are various studies that have found that the higher cephalosporin consumption rate and use ratio have made lower morbidity and mortality caused by COVID-19 than other antibacterials. (bharatbook.com)

Data in the present study adds to the existing evidence that the use of cephalosporins such as cefovecin may be ineffective in many cases (intrinsic resistance of Enterococcus spp ) and therefore should be avoided unless cystocentesis and signalment results support their use. (bvna.org.uk)

The cephalosporin drugs market was valued at approximately USD 14,010 million in 2020, and it is expected to reach USD 16,490 million by 2026, registering a CAGR of 2.75% during the forecast period, 2021-2026. (bharatbook.com)
Eckmanns's department at the RKI has published the recent data on antibiotic resistance surveillance (ARS) in Germany up until 2021. (medscape.com)

One clinically important species from this genus is E. cloacae. (wikipedia.org)

[ 69 ] but emerging resistance is a growing concern. (medscape.com)
1 Urbanization and habitat encroachment have led to an increase in human and wildlife interaction, and antimicrobial resistance is a point of concern in both human and animal medicine. (vin.com)
There is an incoming tide of concern about the problems of antimicrobial resistance. (bmj.com)
November saw the veterinary sector join forces with the NHS to pilot an antibiotic amnesty in response to the ever-growing concern of antibiotic resistance in humans and domestic animals. (bsava.com)

The high occurrence of multidrug resistance among Shigella spp. (biomedcentral.com)

It is widely used against bacterial species like gram-positive cocci, gram-positive rods and gram-negative cocci. (starhealth.in)

We discuss conventional approaches as well as novel strategies, including the use of phage-antibiotic combinations, phage-derived enzymes, exploitation of phage resistance mechanisms, and phage bioengineering. (asm.org)

Resistance develops much less frequently with fourth-generation cephalosporins because they are relatively stable to AmpC beta-lactamase but not (so far) to the less frequently encountered ESBLs (see Medical Care). (medscape.com)
Els estudis de sensibilitat mostren que en les espècies amb una β-lactamasa cromosòmica induïble tipus AmpC (Enterobacter, Citrobacter freundii i Morganella morganii) no hi ha hagut un increment de la resistència a C3G, indicatiu d'una possible desrepressió de l'enzim, essent el percentatge de soques amb fenotip de desrepressió del voltant del 30% en Enterobacter i C. freundii i del 7,5% en M. morganii. (uab.cat)

No additional resistance was found in the isolate from the second pig. (cdc.gov)
Participating health departments forward every 10th non-Typhi Salmonella species isolate from humans received at their public health laboratories to CDC. (cdc.gov)

CDC teamed up with experts at the University of Utah School of Medicine to estimate that treating six antibiotic resistance threats contribute to more than $4.6 billion in health care costs annually. (cdc.gov)
The image shows six of the 18 most alarming antibiotic resistance threats, which cost the U.S. more than $4.6 billion annually. (cdc.gov)
Antibiotic Resistance Threats in the United States, 2019. (pids.org)

Contraindicated in patients with known allergy to cefixime or other cephalosporins. (nih.gov)

In November 2015, a report from China first described plasmid-mediated colistin-resistance caused by the mcr-1 gene. (cdc.gov)

6,7 This study evaluated the genotypic variability and the level of antimicrobial resistance of Enterococcus spp. (vin.com)
Once Enterococcus species colonize the GI tract, the development of antibiotic resistance increases, as does the risk of transmission between patients and providers. (uspharmacist.com)

The genus Nocardia is currently composed of 87 validly described species: 46 of these species are medically relevant ( 16 , 27 , 53 ). (antimicrobe.org)

However, "the proportion of antibiotic resistance varies greatly between countries. (medscape.com)

Intermediate resistance rates are observed against nitrofurantoin, piperacillin/tazobactam, and gentamicin, with increasing resistance observed against tigecycline. (frontiersin.org)

Organisms8

Diseases4

Chemicals and Drugs27

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes13

Antibiotics30

Fluoroquinolones6

Aminoglycosides3

Carbapenems10

Penicillins4

Isolates14

Infections27

Imipenem2

Susceptibility6

ESBL7

Klebsiella9

Coli4

Bacteria22

Enterobacteriaceae4

Second-generation cephalosporins3

Pneumoniae3

Strains5

Enterobacterales1

Cefuroxime1

Cefepime2

Aztreonam1

Commonly4

Quinolones2

Proteus3

Organisms3

Prevalence1

Vancomycin3

Genes3

Pathogens3

Antimicrobial Resistance Monitoring1

Spectrum1

Susceptible1

Antimicrobials4

Third-generation2

Fluoroquinolone1

Clinical3

Staphylococcus1

Enterococci1

Tetracyclines1

Morbidity and morta1

Intrinsic1

20212

Cloacae1

Concern4

Shigella1

Gram-negative1

Enzymes1

AmpC2

Isolate2

Antibiotic resistance threats3

Cefixime1

Colistin1

Enterococcus2

Genus1

Proportion1

Gentamicin1