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Scanning STED-FCS reveals spatiotemporal heterogeneity of lipid interaction in the plasma membrane of living cells. (mpg.de)
A lipid bound actin meshwork organizes liquid phase separation in model membranes. (mpg.de)
STED microscopy detects and quantifies liquid phase separation in lipid membranes using a new far-red emitting fluorescent phosphoglycerolipid analogue. (mpg.de)
Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes. (mpg.de)
Microdomains or lipid rafts greatly affect the distribution of proteins and peptides in the membrane and play a vital role in the formation and activation of receptor/protein complexes. (frontiersin.org)
Even though LRP6 is homogenously distributed in the membrane and only a minor fraction is raft-associated, its localization to lipid rafts is vital for the activation of the LRP6 signalosome, hence wnt/β-catenin signaling. (frontiersin.org)
Lipid rafts are local assemblies of highly concentrated sphingolipids and cholesterol in the cell membrane. (frontiersin.org)
Photomanipulation of minimal synthetic cells: area increase, softening and interleaflet coupling of membrane models doped with azobenzene-lipid photoswitches. (mpg.de)
Biomolecular condensates modulate membrane lipid packing and hydration. (mpg.de)
Rotational decoupling between the hydrophilic and hydrophobic regions in lipid membranes. (mpg.de)
Specific recent and current research topics that contribute to the synthetic biology toolbox for development of artificial cells include membrane texturing through phase separation, artificial DNA adhesion receptors, hybrid lipid-polymer membrane systems for enhanced stability and lifetime, encapsulation of feedback-responsive systems and controlled generation of eukaryote-like membrane architectures. (royalsociety.org)
Not much is known about the lipid biosynthesis of tetraether membranes which confer extremophilic characteristics to archaea. (basyc.nl)

GPI-anchored proteins do not reside in ordered domains in the live cell plasma membrane. (mpg.de)
Multi-protein assemblies underlie the mesoscale organization of the plasma membrane. (mpg.de)
Molecular plasma membrane dynamics dissected by STED nanoscopy and Fluorescence Correlation Spectroscopy (STED-FCS). (mpg.de)
However, according to various experimental measurements, approximately 25 to 35 % of the cell plasma membrane is covered by nanoscopic raft domains with diameters ranging between 10 to 200 nm. (frontiersin.org)
MARV assembles and buds from the host cell plasma where MARV matrix protein (mVP40) dimers associate with anionic lipids at the plasma membrane inner leaflet and undergo a dynamic and extensive self-oligomerization into the structural matrix layer. (uci.edu)

STED-FLCS: An advanced tool to reveal spatiotemporal heterogeneity of molecular membrane dynamics. (mpg.de)
The idea that the dynamics of a system can lead to an increase in its organization has a long history. (wikipedia.org)
However, little is known about the spatiotemporal dynamics of chromatin compaction states because it remains difficult to quantitatively measure the chromatin compaction level in live cells. (sinica.edu.tw)
Here, we demonstrate a strategy, referenced as DYNAMICS imaging, for mapping chromatin organization in live cell nuclei by analyzing the dynamic scattering signal of molecular fluctuations. (sinica.edu.tw)
It will impact both basic research and medicine, since diseases emerge from anomalies in the organisation and dynamics of living systems. (centuri-livingsystems.org)
The Turing Centre addresses the nature of the information underlying biological processes, and the organisation and dynamics of biological structures. (centuri-livingsystems.org)
How does mechanics impact cell and tissue organisation and dynamics? (centuri-livingsystems.org)

The PC/DCM membranes appeared to be asymmetric dense membrane types with appreciable thermal stability, whereas the PC/NMP membranes were observed to be asymmetric with porous structures exhibiting 4.18% and 9.17% decrease in the initial and maximum degradation temperatures, respectively. (afpm.org.my)

Biomimetic asymmetric bacterial membranes incorporating lipopolysaccharides. (mpg.de)
With a background in soft matter and biological physics, his current research interests are encompassed by the physical properties and applications of biomimetic membranes. (royalsociety.org)

Z and the Frontiers of Diversity: one-phase unit T. The characterization species expression is seen to S( and environment) through a search friction. (mariacocchiarelli.com)
High Performance Liquid Chromatographic - Ultra Violet profiling and Liquid Chromatography - Mass Spectral analysis of crude Terminalia coriacea leaves methanolic extract were carried out as a part of chemical characterization to identify bioactive compounds. (afpm.org.my)

Generation of bilayer asymmetry and membrane curvature by the sugar-cleaving enzyme invertase. (mpg.de)
This work proposes bilayer membranes with better electrical conductivity, a higher current efficiency for hydroxyl ions, and a lower tendency to be poisoned than commercial membranes. (mdpi.com)

A growing body of evidence suggests that cell cycle progression and invasion through a basement membrane are mutually exclusive cellular behaviors in both development and disease states (reviewed in Kohrman and Matus, 2017 ). (elifesciences.org)
Membranes (Basel) , 2017 Apr 05;7(2). (afpm.org.my)

The magnitude, direction and timing of contractile force depend on the organization of the cellular actomyosin meshworks and how these networks are connected between cells at the level of the tissue. (nature.com)
Self-organization has also been observed in mathematical systems such as cellular automata. (wikipedia.org)
A growing body of evidence suggests that cell division and basement membrane invasion are mutually exclusive cellular behaviors. (elifesciences.org)
The 19th Annual Wiley Prize in Biomedical Sciences celebrated a breakthrough in cell biology: how membrane-less cellular compartments are formed. (hymanlab.org)

For most individual signaling pathway, this quantitative point of view would imply, that rafts clearly outnumber the membrane-associated pathway components, such as receptor and kinases. (frontiersin.org)

Hydrophobic mismatch sorts SNARE proteins into distinct membrane domains. (mpg.de)
Our simulation experiments indicate, that for receptor/raft ratios smaller than 1, i.e., when the number of raft compartments clearly exceeds the number of pathway specific membrane proteins, we observe significant decrease in LRP6 phosphorylation and downstream pathway activity. (frontiersin.org)
Rational design of synthetic membranes will enable control over the placement and function of membrane components, such as proteins, thus providing an environment for engineering the biotic-abiotic interface when cells and other biomolecules are incorporated. (ebrc.org)

Self-organization is realized in the physics of non-equilibrium processes, and in chemical reactions, where it is often characterized as self-assembly. (wikipedia.org)

The reinforced adhesion of homotypic cell contacts, together with pulsed cell contraction, achieves a biased vertex sliding action by resisting the separation of homotypic cell contacts in boundary cells. (hokudai.ac.jp)

Patterns are ubiquitous in living systems and underlie the dynamic organization of cells, tissues, and embryos. (mpi-cbg.de)

Furthermore, synthetic membranes can fold and reform into controlled architectures like tubes and micelles, as depicted. (ebrc.org)

Instead, when absent, there are alterations in musculoskeletal connective tissue ECM structure, organization, and function, as well as altered skeletal cell phenotypes. (bvsalud.org)
In the nuclei of VU cells, residual NHR-67 protein is compartmentalized into discrete punctae that are dynamic over the cell cycle and exhibit liquid-like properties. (elifesciences.org)
Extrapolating/Translating these values to the membrane of a "normal sized" cell yields a raft abundance, that, by far, outnumbers the membrane-associated pathway components of most individual signaling pathway, such as receptor and kinases. (frontiersin.org)
Using whole-cell electrophysiology, we recorded visual responses of T4 (ON) and T5 (OFF) cells, mapped their composite ON-OFF receptive fields, and found that they share a similar spatiotemporal structure. (janelia.org)
This philosophy from early in my scientific career stuck with me, and I believe was instrumental in my lab's contribution to the discovery of multivalency-driven liquid-liquid phase separation as a general principle in cell organization. (hymanlab.org)

PC/NMP and PC/DCM membranes were fabricated by the dry-wet phase inversion technique and characterized for their morphology, structure, and thermal stability using field emission scanning electron microscopy, Fourier transform infrared spectroscopy, and thermogravimetric analysis, respectively. (afpm.org.my)

Mathematical frameworks have been devised to account for the self-organization of biological patterns, most famously the Turing framework. (mpi-cbg.de)

As such, the organization is typically robust and able to survive or self-repair substantial perturbation. (wikipedia.org)
Unravelling this information could help in engineering more robust membranes in other organisms and in synthetic cells. (basyc.nl)

Composition of pigments from four species of brown seaweeds (Phaeophyceae) collected from Panjang Island, Central Java, Indonesia, was investigated with spectroscopic method and reverse-phase high-performance liquid chromatography (RP-HPLC). (pdfslide.us)
I am basically a Liquid chromatography and mass spectrometry specialist for the Bionanosience department. (basyc.nl)

Self-organization, also called spontaneous order in the social sciences, is a process where some form of overall order arises from local interactions between parts of an initially disordered system. (wikipedia.org)
Chaos theory discusses self-organization in terms of islands of predictability in a sea of chaotic unpredictability. (wikipedia.org)
Self-organization is an example of the related concept of emergence. (wikipedia.org)
Self-organization relies on four basic ingredients: strong dynamical non-linearity, often (though not necessarily) involving positive and negative feedback balance of exploitation and exploration multiple interactions among components availability of energy (to overcome the natural tendency toward entropy, or loss of free energy) The cybernetician William Ross Ashby formulated the original principle of self-organization in 1947. (wikipedia.org)
It notes that self-organization is facilitated by random perturbations ("noise") that let the system explore a variety of states in its state space. (wikipedia.org)
The philosopher René Descartes presents self-organization hypothetically in the fifth part of his 1637 Discourse on Method. (wikipedia.org)

Efficient liposome fusion to phase-separated giant vesicles. (mpg.de)

Upon nanoelectromechanical confinement between two graphene layers, water forms a 2D ice phase at room temperature that exhibits a strong and permanent dipole which depends on the previously applied field, representing clear evidence for ferroelectric ordering. (sinica.edu.tw)

X-ray diffraction measurements, Fourier transform infrared spectroscopy, and X-ray photoelectron spectroscopy clarified that an amorphous phase and Li2CO3 were produced on the Li4SiO4 surface after the CO2 reaction in the presence of water vapor. (academic-accelerator.com)

Therefore, the PC/DCM membranes with dense morphologies are appropriate for gas separation applications. (afpm.org.my)

The resulting organization is wholly decentralized, distributed over all the components of the system. (wikipedia.org)

Modified membranes enable the removal of excess alkali in conventional electrodialysis modules, thus reducing the operational and capital costs of processing the sodium naphthenate solution. (mdpi.com)

Membrane orientation and lateral diffusion of BODIPY-cholesterol as a function of probe structure. (mpg.de)

The ideal CO₂/N₂ and CO₂/CH₄ selectivities of the PC/NMP membrane decreased with the increase in feed pressures, while for the PC/DCM membrane, the average ideal CO₂/N₂ and CO₂/CH₄ selectivities were found to be 25.1 ± 0.8 and 21.1 ± 0.6, respectively. (afpm.org.my)

Among the most common biogenic minerals formed are calcite and aragonite, which support the three-dimensional (3D) organisation of mollusks, echinoderms, calcisponges, corals, certain algae and others. (nature.com)
In flapping insect wings, veins support flexible wing membranes such that the wings form feathering and cambering motions passively from large elastic deformations. (cfd-online.com)

Diverse sensory systems, from audition to thermosensation, feature a separation of inputs into ON (increments) and OFF (decrements) signals. (janelia.org)

We here report on the direct observation of ferroelectric properties of water ice in its 2D phase. (sinica.edu.tw)
The phase separation behavior of bisphenol-A-polycarbonate (PC), dissolved in N-methyl-2-pyrrolidone and dichloromethane solvents in coagulant water, was studied by the cloud point method. (afpm.org.my)

ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. (thermofisher.com)

versus the membrane transport for the explicit countries achieved in path 1 deformations the various standard spectrum and symmetric sn between the m. and the membrane crystal made in Hope 5 for three NO2 results of types considered in parcel Computing the comparable second A and the technology solution a for each activation of the ECS occurs article s and strongly HT003029. (taido-hannover.de)
Each, synergistically, made groundbreaking contributions to the discovery that membrane-less organelles are liquid-liquid phase-separated entities. (hymanlab.org)

From view Милюков to phase neighbor, the pollution between solver, Orbits, and r is the evolution between all machines in the injury. (taido-hannover.de)

Importantly, in the LFPs tuned to serial order, there was a strong bias toward the continuation phase for the β-band when aligned to movements, and a bias toward the synchronization phase for the γ-band when aligned to the stimuli. (jneurosci.org)

Metzger, Philip T. Methodologies to produce Frontiers of Diversity: Explorations in content, Then infected on natural interactions large to the anion of phase medium and differential cities, have scaled and used. (mariacocchiarelli.com)

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