Southern african ancient genomes. Medical search. Frequent questions

So we thought okay, given the difficulties of working with human remains in South Africa, we would start with sediments, and we ran through quite a few data sets. (ogresearchconservation.org)
A study team from Uppsala University in Sweden, the Universities of Johannesburg and the Witwatersrand in South Africa present their findings in the early online issue of Science on September 28th. (theafricanhistory.com)
The three oldest individuals, who lived between 2300 and 1800 years ago, were genetically related to southern Khoe-San ancestors, while the four younger individuals, who lived between 500 and 300 years ago, were genetically related to modern-day Bantu-speaking populations in South Africa. (theafricanhistory.com)
A comparison between an early Stone Age hunter-gatherer youngster from Ballito Bay on the east coast of South Africa and the West African Mandinka is represented by the deepest split time of 350,000 years ago. (theafricanhistory.com)
According to Marlize Lombard, "South Africa was populated by tool-making hunter-gatherers at the time of the split, according to archaeological deposits going back 350,000-260,000 years. (theafricanhistory.com)
He worked at the Bernard Price Institute for Paleontological Research in South Africa. (asu.edu)
and Cape lions of South Africa. (nationalgeographic.com)

The number does not include Southern Twa populations, who live outside of the Central Africa forest environment, partly in open swamp or desert environments. (wikipedia.org)
African Pygmy" is used for disambiguation from "Asiatic Pygmy", a name applied to the Negrito populations of Southeast Asia. (wikipedia.org)
The ancestry of the individuals in our study area can be modelled as a geographically structured mixture of three highly divergent source populations, probably reflecting Pleistocene interactions around 80-20 thousand years ago, including deeply diverged eastern and southern African lineages, plus a previously unappreciated ubiquitous distribution of ancestry that occurs in highest proportion today in central African rainforest hunter-gatherers. (nature.com)
The structure of ancient populations cannot be robustly reconstructed based solely on genetic data from present-day people. (nature.com)
The first large-scale study of ancient human DNA from sub-Saharan Africa opens a long-awaited window into the identity of prehistoric populations in the region and how they moved around and replaced one another over the past 8000 years. (garvan.org.au)
The research team compared the 15 ancient genomes-along with the only other known ancient genome from the region, previously published in 2015-against those of nearly 600 present-day people from 59 African populations and 300 people from 142 non-African groups. (garvan.org.au)
The last few thousand years were an incredibly rich and formative period that is key to understanding how populations in Africa got to where they are today," said David Reich , professor of genetics at HMS and a senior associate member of the Broad Institute of Harvard and MIT. (garvan.org.au)
We need to ensure we use it for the benefit of all populations around the world, perhaps especially Africa, which contains the greatest human genetic diversity in the world but has been underserved [by the genomics community]. (garvan.org.au)
In addition to admixture among modern human populations, ancient humans reproduced with other hominin groups, such as Neanderthals and Denisovans. (news-medical.net)
Because of this, Africa contains the highest levels of genetic diversity and population structure among humans, with non-African populations largely representing a subset of the genetic variation present on the African continent. (news-medical.net)
In the article 'Evolutionary Genetics and Admixture in African Populations,' researchers from two institutes - Georgia Institute of Technology and Mediclinic Precise Southern Africa - reviewed how multiple demographic events have shaped African genomes over time (Pfennig, et al. (news-medical.net)
For example, ancient introgression from archaic 'ghost' populations of hominins that are no longer extant contributed approximately 4-6% of the ancestry of present-day Khoe-San, Mbuti, and western African populations. (news-medical.net)
More recent demographic events that have occurred over the last 10,000 years have similarly resulted in admixture among modern humans, including gene flow among different click-speaking Khoe-San populations, the spread of pastoralism from eastern to southern Africa, and migrations of Bantu speakers across the continent. (news-medical.net)
Subsequent migration of Europeans and Africans due to European colonization and the Transatlantic slave trade resulted in admixed populations that combine ancestries from different continents. (news-medical.net)
They used data from the 1000 Genomes Project that were acquired from several admixed populations, including Colombians from Medellin, individuals with Mexican Ancestry from Los Angeles, Peruvians from Lima, and Puerto Ricans from Puerto Rico. (news-medical.net)
In 2016, Schuster and Mahesh Pratapneni, with support from the Nanyang Technological University, EmergeVentures, Medgenome , and Macrogene , founded the GenomeAsia100K initiative, which sequences human genomes from Asian human populations. (stephanschuster.com)
rted to unveil the genetic heritage of Ethiopian populations, who are among the most diverse in the world, and lie at the gateway from Africa. (amandlanews.com)
They found that the genomes of some Ethiopian populations bear striking similarities to those of populations in Israel and Syria, a potential genetic legacy of the Queen of Sheba and her companions. (amandlanews.com)
The team detected mixing between some Ethiopians and non-African populations dating to approximately 3,000 years ago. (amandlanews.com)
Little was previously known about the populations inhabiting the North-East African region from a genomic perspective. (amandlanews.com)
This is the first genome study on a representative panel of Ethiopian populations," explains Luca Pagani, first author from the Wellcome Trust Sanger Institute and the University of Cambridge. (amandlanews.com)
They found that the Ethiopian genome is not as ancient as was previously thought and less ancient than the genomes of some Southern African populations. (amandlanews.com)
We found that some Ethiopians have 40-50% of their genome closer to the genomes of populations outside of Africa, while the remaining half of their genome is closer to populations within the African continent," says Dr. Toomas Kivisild, co-author from the University of Cambridge. (amandlanews.com)
Next, the researchers combined their genetic analysis with other lines of evidence to infer where ancient populations lived and moved. (insidescience.org)
Results Here we show that accurate genomic estimates of the divergence times between European and African populations are more recent than those between Australo-Melanesia and Africa, and incompatible with the effects of a single dispersal. (biorxiv.org)
Previous studies have shown that the modern populations in these countries have genes that have flowed in from West Asia, so the researchers masked these modern Eurasian contribution to the genomes. (thecanadiancharger.com)
They found that the remaining genomic regions from the Egyptian samples were more similar populations who lived outside Africa than the remaining regions in the Ethiopian samples. (thecanadiancharger.com)
The researchers also estimated that people European and Asian populations appear to have split from the Egyptian genomes around 55,000 years ago. (thecanadiancharger.com)
To answer this, we need ancient genomes from populations along the possible routes. (thecanadiancharger.com)
The authors compared mitochondrial DNA from different human populations worldwide, and from those comparisons they argued that all human populations had a common ancestor in Africa around 200,000 years ago. (asu.edu)
You can see the K12b admixtures of ancient populations and regional evolutions over a period of 15,000 years from the Epipaleolithic to the Middle Ages on the Ancient Ethnicities Analyzer page. (eupedia.com)
this is the most accurate Ancestry based calculator to date which is based on ancient populations. (geneplaza.com)
This calculator uses higher coverage ancient genomes from the aforementioned as well as previous studies to represent the various Neolithic, Chalcolithic, and Bronze Age cultures, stretching from western Europe all the way to central Asia and Siberia, and which contributed to the genetic makeup of the various modern populations currently residing across Eurasia. (geneplaza.com)

Haplogroup E is still common today in north Africa and across southern Europe. (familytreedna.com)

Anatomically modern humans (AMH), defined by a lightly built skeleton, a large brain, reduced face and prominent chin, first appear in the East African fossil record around 200,000 years ago [ 1 , 2 ]. (biorxiv.org)
In this way, scientists were able to discover what is famously penned today in the popular culture as " Mitochondrial Eve ", the matrilineal most recent common ancestor (MRCA), which suggested that modern humans descended in a direct, unbroken, maternal line to a single female ancestor who lived approximately 100,000-200,000 years ago, most likely in East Africa. (popular-archaeology.com)
The accepted view is that Homo sapiens evolved in Africa 200,000 years ago and stayed there until 60,000 years ago, when they struck out through the Middle East and spread around the world. (pearltrees.com)

The Ballito Boy has been a breakthrough in the understanding of not only what diseases afflicted our ancestors, but of the very definition of "human", according to the findings of the team who sequenced his genome in 2017, and on whose work Rifkin and his team drew. (ogresearchconservation.org)
Together with genetic analyses of ancient human remains from Africa published [ in 2017 ] the latest data are starting to fill in the nearly blank canvas of early human history. (swallowxx.com)

The African Pygmies (or Congo Pygmies, variously also Central African foragers, "African rainforest hunter-gatherers" (RHG) or "Forest People of Central Africa") are a group of ethnicities native to Central Africa, mostly the Congo Basin, traditionally subsisting on a forager and hunter-gatherer lifestyle. (wikipedia.org)
Additionally, West African hunter-gatherers may have dwelled in western Central Africa earlier than 32,000 BP and dwelled in West Africa between 16,000 BP and 12,000 BP until as late as 1000 BP or some period of time after 1500 CE. (wikipedia.org)
West African hunter-gatherers, many of whom dwelt in the forest-savanna region, were ultimately acculturated and admixed into larger groups of West African agriculturalists, akin to the migratory Bantu-speaking agriculturalists and their encounters with Central African hunter-gatherers. (wikipedia.org)
The use of "Pygmy" in reference to the small-framed African hunter-gatherers dates to the early 19th century, in English first by John Barrow, Travels Into the Interior of Southern Africa (1806). (wikipedia.org)
We did not find any evidence of deep structure or archaic admixture among southern African Stone Age hunter-gatherers, instead, we see some evidence for deep structure in the West African population, but that affects only a small fraction of their genome and is about the same age as the deepest divergence among all humans," says Mattias Jakobsson. (theafricanhistory.com)
The Ballito Bay kid and other San hunter-gatherers lived in southern Africa 2000 years ago, therefore these fossils could be their ancestors. (theafricanhistory.com)
To clarify the dynamics of the interaction between the first farmers and indigenous hunter-gatherers where they first met, we analyze genome-wide ancient DNA data from 223 individuals who lived in southeastern Europe and surrounding regions between 12,000 and 500 BCE. (blogspot.com)
The findings also suggest that there was intermingling during that period between the Hadza, the San in southern Africa and the Baka in central Africa, all of whom were traditionally hunter-gatherers. (swallowxx.com)

The Bacho Kiro men happen to be ancient forms of haplogroups C and F, which were among the first to either leave Africa or evolve in the Middle East once humans first left Africa some 55,000 years ago. (familytreedna.com)
This suggests Egypt was the last stop for people migrating out of Africa 55,000 years ago rather than taking a more southerly route through Ethiopia. (thecanadiancharger.com)

The next step for our research has to be to sequence the entire genomes, rather than read individual letters, of both Ethiopian people and others to really understand human origins and the out-of-Africa migration. (amandlanews.com)
To conduct their research, which is published in the American Journal of Human Genetics , the researchers analysed the entire genomes of 225 people from modern Egypt and Ethiopia. (thecanadiancharger.com)

Based on ancient Stone Age hunter-gatherer genomes, the scientists estimate that the separation between modern humans happened between 350,000 and 260,000 years ago. (theafricanhistory.com)
Entitled "DNA Clues to Our Inner Neanderthal", he explained how he and his team of scientists have been able to look into the complex elements of the human genome and ferret out the telltale signs of these prehistoric human cousins within our own ancestry. (popular-archaeology.com)
After conducting further analyses, Tishkoff plans to publish the results and share the anonymized genomes publicly, so that scientists can pool their data. (swallowxx.com)
For the first time, scientists sequenced the genomes of 20 individual lions, including extinct cave lions, revealing insights into their family tree. (nationalgeographic.com)
To help save the world's remaining lions and better understand how the different types are related, an international team of scientists created complete genomes of 20 individual lions, 14 of which died long ago, including two 30,000-year-old cave lions preserved in permafrost in Siberia and the Yukon. (nationalgeographic.com)

But as you sequence genomes there's a lot of extra data that comes out. (ogresearchconservation.org)
This enabled the comparison of 18 complete mammoth mitochondrial genomes (mt genome) to those of a single Indian and single African Elephant mt genome sequence ( 7 ). (stephanschuster.com)
Emile Zuckerkandl and the physical chemist Linus Carl Pauling introduced the term "paleogenetics" in 1963, and in 1984 a team led by Allan Wilson published the achievement of the first sequence of ancient DNA isolated from the remains of the quagga , an extinct form of zebra. (popular-archaeology.com)

From their geographic location, it is logical to think that migration out of Africa 60,000 years ago began in either Ethiopia or Egypt. (amandlanews.com)
It is exciting that, in our genomic era, the DNA of living people allows us to explore and understand events as ancient as 60,000 years ago. (thecanadiancharger.com)

Taken together, we propose a southern African origin of anatomically modern humans with sustained homeland occupation before the first migrations of people that appear to have been driven by regional climate changes. (nature.com)
For example, did other migrations also leave Africa around this time, but leave no trace in present-day genomes? (thecanadiancharger.com)
The study's results support the idea that lions radiated out of Africa in a series of migrations, somewhat analogous to humans, Barnett says. (nationalgeographic.com)

The researchers analysed the genomes of seven people who lived between 2300 and 300 years ago in southern Africa. (theafricanhistory.com)

The Omo and Herto fossils from east Africa, in particular, have been used to date the emergence of anatomically modern humans to around 180,000 years ago. (theafricanhistory.com)
As a result, both palaeoanthropological and genetic evidence increasingly points to multiregional origins of anatomically modern humans in Africa," says Carina Schlebusch. (theafricanhistory.com)

Mitochondria DNA (mtDNA) is a small circular genome found in the subcellular organelles, called mitochondria. (asu.edu)

There are many examples of population divergence followed by secondary contact, the legacy of which is written in our genomes. (news-medical.net)
The Florisbad and Hoedjiespunt fossils, which were contemporaneous with the small-brained Homo naledi in southern Africa, correspond to the deeper estimate for modern human divergence at 350,000-260,000 years ago. (theafricanhistory.com)

Homo sapiens a apărut acum 300.000-200.000 de ani în urmă, [5] cel mai probabil în Africa, iar Homo neanderthalensis a apărut aproximativ în același timp în Europa și Asia de Vest. (wikipedia.org)
It now seems that at least two or three Homo species occupied the southern African landscape during this time period, which also represents the early phases of the Middle Stone Age," says Marlize Lombard. (theafricanhistory.com)
The study has answered a long standing question about the route early Homo sapiens took when spreading from the African continent. (thecanadiancharger.com)
This suggests that Egypt was most likely to be the gateway through which Homo sapiens spread out of Africa around the world. (thecanadiancharger.com)
Although Homo sapiens originated in Africa roughly 250,000 to 315,000 years ago, geneticists have devoted their attention almost exclusively to the small subset of Africans that migrated north to Europe tens of thousands of years later. (swallowxx.com)

A sword used by a Roman soldier during the brutal pacification of the Jews and the destruction of the Temple at Jerusalem nearly 2,000 years ago, has emerged from an ancient drainage tunnel beneath the city, Israeli authorities announced this week. (sott.net)

University of Pretoria), answer several longstanding mysteries and uncover surprising details about sub-Saharan African ancestry-including genetic adaptations for a hunter-gatherer lifestyle and the first glimpses of population distribution before farmers and animal herders swept across the continent about 3000 years ago. (garvan.org.au)
Although ancient-DNA research has revealed insights into the population histories of many areas of the world, delving into the deep ancestry of African groups wasn't possible until recently because genetic material degrades too rapidly in warm, humid climates. (garvan.org.au)
Importantly, biomedical studies often fail to capture this diversity, resulting in implications for the health and disease of those with African ancestry. (news-medical.net)
In the study, researchers from Brown University, the Universidad Nacional Autónoma de México, and the University of California-Merced analyzed how the resulting gene flow between modern humans redistributed archaic ancestry in admixed genomes. (news-medical.net)
Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans. (familytreedna.com)
From a genomic perspective, we are all Africans," he said with clear assurance-his work has also helped to show that all humans can trace their ancestry far back to a small population of Africans who later expanded and spread out across the globe. (popular-archaeology.com)
There is a history buried deep within our living genes, a history that could possibly take us back to glimpse the primordial soup of our human ancestry, perhaps even as far back as the ancient proto-humans who walked the world long before modern humans. (popular-archaeology.com)
True, there is quite often a clear trace of Middle Eastern and African ancestry among the Muslims of South Asia above and beyond what may be found amongst non-Muslims, but often this component is dwarfed by a minor East Asian element which seems to warrant no cultural memory! (sepiamutiny.com)
I think we are seeing an ancient common ancestry between the major hunter-gatherer groups in Africa," [geneticist Sarah] Tishkoff says. (swallowxx.com)
And before I knew it, I was scrolling through what felt like an online genealogic red-light district, a sensory overload of temptation and promises of fantasies fulfilled: "Use DNA to illuminate the past and bring ancient ancestry to life" … click … "The only way to know where you come from is by reading your DNA" … click … "Are you adopted and curious about your heritage? (popsci.com)

Carina Schlebusch, a population geneticist at Uppsala University, adds, "This indicates the population replacement that occurred in southern Africa. (theafricanhistory.com)

Here we generate, to our knowledge, the largest resource for the poorly represented and deepest-rooting maternal L0 mitochondrial DNA branch (198 new mitogenomes for a total of 1,217 mitogenomes) from contemporary southern Africans and show the geographical isolation of L0d1'2, L0k and L0g KhoeSan descendants south of the Zambezi river in Africa. (nature.com)
He extensively sequenced the mitochondrial DNA genes of the four species of African green monkeys. (science20.com)
They modeled historical climate across southern Africa, and compared the times when the climate changed to branching events in the mitochondrial DNA tree. (insidescience.org)
By Steven Strong Contributing Writer for Wake Up World Scientific evidence refuting the theory of modern humanity's African genesis is common knowledge among those familiar with the most recent scientific papers on the human Genome, Mitochondrial DNA and Y-chromosomes. (pearltrees.com)

Here we present new genome-wide aDNA data and radiocarbon dates from three Late Pleistocene and three early to middle Holocene individuals associated with LSA technologies at five sites in eastern and south-central Africa: Kisese II and Mlambalasi Rockshelters in Tanzania, Fingira and Hora 1 Rockshelters in Malawi, and Kalemba Rockshelter in Zambia (Fig. 1a and Extended Data Table 1 ). (nature.com)
Figure 1 from The genome of a Late Pleistocene human from a Clovis burial site in western Montana. (familytreedna.com)

The efforts of Schuster and his main collaborator, Webb Miller , eventually led to the first genome of an extinct species, the mammoth genome, published in Nature magazine in 2008 ( 13 ). (stephanschuster.com)
He and his team are known for developing a methodology for isolating and sequencing actual ancient DNA by sampling the remains of extinct human species. (popular-archaeology.com)
Ancient tools, extinct animal remains provide evidence of early human occupation. (popular-archaeology.com)
Extinct cave lions ( Panthera leo spelaea ) likely lacked manes, perhaps making them unappealing to African lions. (nationalgeographic.com)

They wanted to see how the human genome fitted the "Out of Africa hypothesis", and it clarified the fact that our ancestors did evolve in Africa and that we all have an ancestor in Africa. (ogresearchconservation.org)
The arrows on this map of Africa illustrates the UA researchers' hypothesis that SIV first infected the westernmost species of African green monkey and then moved east across the continent. (science20.com)
You are not going to persuade me on fallacious reasoning (like claiming that Black Africans are somehow naturally polygynistic, a false assumption in itself) of such rather weirdo alternative hypothesis as the ones you have posted in this thread. (blogspot.com)

We analyse these data together with the published sequences of 28 other ancient African individuals recovered from contexts spanning the past 8,000 years and largely associated with foraging at 17 sites in eastern, central and southern Africa. (nature.com)

That joint Swedish-South African study found that his DNA timed the split between modern humans and archaic or pre-human groups between 350 000 and 260 000 years ago. (ogresearchconservation.org)
As recently documented, the shift from archaic to modern humans may not have occurred in just one location in Africa, but in numerous, including southern and northern Africa. (theafricanhistory.com)

More than half of the DNA of many of the individuals from coastal towns originates from primarily female ancestors from Africa, with a large proportion-and occasionally more than half-of the DNA coming from Asian ancestors. (bvsalud.org)
Another rare, yet crucial, evolutionary haplogroup common in our Paleolithic ancestors was haplogroup K. We first see the haplogroup in Central Asia 42,000 years ago in a man from the Ust-Ishim district of southern Siberia. (familytreedna.com)
Other parts of our genome can theoretically be traced to different common ancestors. (insidescience.org)
Kitching recovered fossils of early human ancestors, later called Australopithecines, as well as fossils of dinosaurs and ancient mammals. (asu.edu)
Surprisingly, though, cave lions and ancestors of today's African lions didn't interbreed, the genetic analysis reveals. (nationalgeographic.com)
Aug 8 2014 OUR direct ancestors may have found their way out of Africa much earlier than we think. (pearltrees.com)

Here we present genome-wide ancient DNA data for six individuals from eastern and south-central Africa spanning the past approximately 18,000 years (doubling the time depth of sub-Saharan African ancient DNA), increase the data quality for 15 previously published ancient individuals and analyse these alongside data from 13 other published ancient individuals. (nature.com)
Altogether, the team coaxed DNA from the skeletal remains of 15 sub-Saharan African individuals who came from a variety of geographical regions and lived up to 8500 years ago. (garvan.org.au)
Hayes contributed genomic information from one of these individuals - a male in his 50s who lived about 2000 years ago, found at St Helena Bay at the southern tip of Africa. (garvan.org.au)
Yves Vanderhaeghen speaks to Dr Riaan Rifkin about the pioneering gene-sequencing by a team of South African researchers which sheds light on a pathogen which infected a child 2000 years ago. (ogresearchconservation.org)
He hopes ultimately to reconstruct how diseases shaped the human condition, both biologically and culturally, from the origins of the species to its exodus from Africa about 60 000 years ago, taking a host of diseases with it. (ogresearchconservation.org)
And then we came across a publication by colleagues of ours a few years ago on Ballito Bay, and they were only interested in the human genome. (ogresearchconservation.org)
The team found that these two groups of African and non-African people mixed approximately 3,000 years ago, well before the historically-documented Islamic expansions and the colonial period of the last centuries. (amandlanews.com)
An earlier study found that Ethio-Semitic, an Ethiopian language belonging to a linguistic family primarily spoken in the Middle East, split from the main Semitic group 3,000 years ago, around the same time as the non-African genomic component arrived in Ethiopia. (amandlanews.com)
Among the oldest ancient connections in our database are three individuals who lived some 45,000 years ago in what is today Bacho Kiro, Bulgaria, in southeastern Europe. (familytreedna.com)
For comparison, Hora 19529 from Malawi belongs to haplogroup B and, at 14,000 years old, is the oldest sample sequenced from sub-Saharan Africa. (familytreedna.com)
The new work suggests African green monkeys' SIVs, or SIVagm, may have lost their virulence more recently than the millions of years previously thought. (science20.com)
The authors also discovered that a little over a thousand years ago, all current-day Khoe-San communities admixed with migrating East African pastoralists. (theafricanhistory.com)
Recently, he was part of a NSF sponsored research project that discovered a human burial dating to 4,500 years ago and led to the extraction of ancient DNA, sequencing for the first time an African ancient genome. (usf.edu)
The team extracted a DNA sample from a humerus bone found in the Klondike permafrost sediment, which is at least 47,500 years old, and mapped out its nuclear genome. (easydna.co.uk)
The main exit from Africa, through the Levant, has been dated around 56,000 years ago [ 10 , 11 ]. (biorxiv.org)
Peking Man is an ancient Chinese ape-man that lived as much as 750-thousand years ago. (sott.net)
Over the past 150 years, the global population of African lions has declined by more than 20-fold to fewer than 25,000, mostly due to hunting and habitat loss. (nationalgeographic.com)
Cave lions came out first, splitting from their African kin about 500,000 years ago, according to the paper. (nationalgeographic.com)
Africa , Egypt for example was a hub for education across the world for many years as it use to house many research scrolls hidden away or kept in the chambers of its now destroyed libraries. (riazhaq.com)

This resulted in fragments of DNA from these ancient lineages being passed down to modern humans in a process known as introgression. (news-medical.net)

What I find confusing is their statement that they can be modeled genetically as a two source admixture between Mediterranean Europeans and Southern Africans. (eupedia.com)
At least we can know if Arabian, SSA, Turks and Europeans had significant impact among local North African gene-pool. (eupedia.com)

However, it is unclear whether early modern humans left Africa through a single, major process, dispersing simultaneously over Asia and Europe, or in two main waves, first through the Arab peninsula into Southern Asia and Oceania, and later through a Northern route crossing the Levant. (biorxiv.org)
The findings also support evidence that these first humans to leave Africa came into contact with Neanderthals in the Levant at the time. (thecanadiancharger.com)

Hayes is a world-renowned expert in the genomics of both contemporary and ancient Africans. (garvan.org.au)
And this was the first hunter gatherer disease found for the whole of Africa," says lead researcher on the project, Dr Riaan Rifkin, an anthropologist and prehistoric archaeologist based at the Centre for Microbial Ecology and Genomics at the University of Pretoria. (ogresearchconservation.org)
Applying the emerging NGS technology to ancient DNA research, together with the use of novel DNA reservoirs (hair) ( 6 ), eventually led to the field of paleo-population genomics . (stephanschuster.com)
Mick Westbury, another co-author of the study and a specialist in paleo-genomics, agrees and notes that the technological advancements in the field have made studying ancient DNA not only easier but also more cost-effective. (easydna.co.uk)
A handful of African genomics projects are now beginning to address this imbalance. (swallowxx.com)

She says, "We think of Africa as the cradle of civilisation - but it's easy to forget that there was an immense amount of population movement across the continent, long before we humans left Africa. (garvan.org.au)
Background Anthropological and genetic data agree in indicating the African continent as the main place of origin for modern human. (biorxiv.org)
Humankind's early history in Africa is coming into sharper focus with a new study of 180 genomes from a dozen ethnic groups on the continent - some of which have never before been analysed. (swallowxx.com)
The discrimination and injustices towards this ancient race, which had lived on the American continent long before the European conquerors came to this land, are still present to this day despite the efforts of different groups and organizations trying to restore justice. (pearltrees.com)

The first modern human dispersals across Africa. (nature.com)
These results offer an excellent set of predictions which we used in the present study to test whether current genomic diversity is better accounted for by processes involving a Single major Dispersal (hereafter: SD) or Multiple major Dispersals (hereafter: MD) from Africa. (biorxiv.org)

2023). According to Joseph Lachance, one of the review's authors, 'What stands out is the sheer complexity of human demographic history, especially in Africa. (news-medical.net)

Two recent studies published in Genome Biology and Evolution examine patterns of admixture in two different regions of the world-;Africa and the Americas-;revealing how this process has shaped the genomes of modern humans. (news-medical.net)
Once occupying southern Africa across Europe and Asia and even into the Americas, the scimitar-toothed cat is said to have genetic traits indicating that it had excellent eyesight and was well-suited to daytime hunting. (easydna.co.uk)

One avenue for better understanding the genetic architecture of African genomes is the study of ancient DNA: 'Going forward, analysis of ancient DNA is expected to become much more common. (news-medical.net)
Our study was the first in Southern Africa to detect ancient pathogen DNA, the first time we could tell that individual X had a certain pathogen that might had led to his or her death. (ogresearchconservation.org)
We've known for a long time that modern humans originated in Africa … but what we haven't known until this study was where exactly this homeland was. (insidescience.org)
A fossil of a scimitar-toothed cat found near Dawson City would lead to a newly-published study on the behavioral traits of these ancient cats , including hunting in a group and pursuing prey to the point of exhaustion. (easydna.co.uk)
Zazula also talks about the contribution of the study in highlighting new opportunities for paleontologists to conduct DNA and genome analyses. (easydna.co.uk)
Dr Toomas Kivisild, an anthropologist at the University of Cambridge who helped lead the study, said: 'While our results do not address controversies about the timing and possible complexities of the expansion out of Africa, they paint a clear picture in which the main migration out of Africa followed a Northern, rather than a Southern route. (thecanadiancharger.com)
Daniel Romero-Alvarez] That question is the reason why I started to study leprosy disease system, because we might believe that because it's an ancient disease--we know leprosy since very, very old times--then the mechanisms of transmission will be completely clear for us. (cdc.gov)

Africa is the birthplace of humanity, where our species originated and diversified. (news-medical.net)
A new family tree for African green monkeys shows that an HIV-like virus, simian immunodeficiency virus, or SIV, first infected those monkeys after the lineage split into four species. (science20.com)
The new research also challenges the idea that one ancient SIV was transmitted vertically, down through time, and evolved into many SIVs as its original host diverged into many different species. (science20.com)
Previous research had sketched out the family trees, or phylogenies, of the four species of African green monkeys and their accompanying SIVagm, but Wertheim wanted to know more. (science20.com)
If the monkeys' ancestor had been infected with an ancient SIV, the SIV family tree should match that of the four monkey species. (science20.com)
The researchers then looked at the geographic distribution of the four African green monkey species. (science20.com)
The UA researchers suggest that in the border zones where two African green monkey species' ranges come in contact, transmission probably happened during interspecies sexual encounters or fights. (science20.com)
the plant species has been described as native to India, where it continues to grow wild, [10] Africa, [11] or South Asia. (wikipedia.org)
The existence of a mysterious ancient human lineage and the possibility that the earliest humans were actually all one species were among the human-evolution-related discoveries of 2013. (pearltrees.com)

We see imprints of historical events on top of much more ancient prehistoric ones that together create a region of rich culture and genetic diversity. (amandlanews.com)

What's confusing to me is that they're saying that these people are not all that related to modern North Africans. (eupedia.com)
If they're really just a unique blend of slaves from different parts of the world it's not going to tell us much about the population genetics of modern North Africans. (eupedia.com)
In 2010, she and her team determined the first genomes from modern-day Africans (Archbishop Desmond Tutu and !Gubi, a Kalahari bushman from Namibia). (garvan.org.au)
Here we report ancient DNA data for 80 individuals from 6 medieval and early modern (AD 1250-1800) coastal towns and an inland town after AD 1650. (bvsalud.org)
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. (nature.com)
You can also easily compare your own results with ancient and modern ones with the Vahaduo tool in link on that page. (eupedia.com)

Masu ilimin ƙasa sun jawo bambancin bambancin al'adu tsakanin yankin Sudan da kwatankwacinsa Zanj, daga yankin zuwa gabas mai iyaka a bakin tekun Jar a Horn of Africa. (wikipedia.org)
Ethiopia is situated in the horn of Africa, and has often been regarded as one of the gateways from Africa to the rest of the world. (amandlanews.com)

Direct and indirect dates range from around 18 ka to 5 ka, doubling the time depth of aDNA reported from sub-Saharan Africa. (nature.com)
We put together, for the first time, a really solid phylogeny for African green monkeys, which we didn't have before," Worobey said. (science20.com)
This was the early 1940s in southern Illinois - a time and place when people whispered about things like mixed race, if they talked about it at all. (popsci.com)

Similarly, by adding present-day genomes from Oceania, we can discover whether or not there was a separate, perhaps Southern, migration to these regions. (thecanadiancharger.com)

The samples were processed in a designated ancient DNA lab and the genomic data obtained shows standard patterns of authentic ancient DNA with low levels of contamination. (eupedia.com)

Dembner (1996) reported a universal "disdain for the term 'pygmy'" among the Pygmy peoples of Central Africa: the term is considered a pejorative, and people prefer to be referred to by the name of their respective ethnic or tribal groups, such as Bayaka, Mbuti and Twa. (wikipedia.org)
We can now discover admixture percentages in all San tribes because we have access to ancient DNA of people who lived on the landscape before the East African migration. (theafricanhistory.com)
The rarer branch is called L0, and its signature DNA types are found almost exclusively in people living in southern Africa. (insidescience.org)
Chinese archaeologists have found new evidence to show that ancient Chinese people knew how to use fire. (sott.net)
The fire pits and ashes could be the relics showing the use of fire and the cave-life of ancient Chinese people. (sott.net)

On Mount Shoria in southern Siberia, researchers have found an absolutely massive wall of granite stones. (pearltrees.com)

These new higher quality genomes greatly added to our understanding of the population demography of Europe, Western, Central, and South Asia. (geneplaza.com)

Ancient DNA is the only tool we have for characterizing past genomic diversity. (garvan.org.au)
Regardless of whether there was a single major expansion or two, several DNA studies clearly showed that genetic diversity tends to decrease [ 21 , 22 ] and linkage disequilibrium to increase [ 23 , 24 ] at increasing distances from Africa. (biorxiv.org)

The advent of genome-wide ancient DNA (aDNA) technology holds promise for better understanding major changes in material culture and hypothesized demographic shifts among ancient African foragers (Supplementary Notes 1 , 2 ). (nature.com)
Recovering and studying ancient DNA (aDNA) from long-dead organisms tells only part of the story. (popular-archaeology.com)

Any older hominin bones found outside Africa are deemed dead ends. (pearltrees.com)

Atât în Africa, cât și în Eurasia, H. sapiens a întâlnit și s-a încrucișat [6] [7] cu oameni arhaici . (wikipedia.org)

Fig. 2: L0 phylogenetic tree, geographical distributions of the major southern African L0 haplogroup and out-of-homeland L0 dispersal routes. (nature.com)

The team's research article, "A Challenge to the Ancient Origin of SIVagm Based on African Green Monkey Mitochondrial Genomes," is in the July issue of PLoS Pathogens and can be found at http://www.plospathogens.org . (science20.com)
They found that when L0 split off from the rest of the mitochondrial lineage, much of southern Africa would have been dry and inhospitable. (insidescience.org)
The first known written record of the plant is found in Qimin Yaoshu , an ancient Chinese agricultural treatise completed in 544 CE. (wikipedia.org)

Here then is a hint that the behaviours of an ancient wolf population are beginning to diversify. (ukpets.co.uk)
Future studies are also likely to focus on fine-scale population structure in Africa. (news-medical.net)
Before, we didn't have an un-admixed San population to serve as a reference, therefore we couldn't discover this broad East African mixing. (theafricanhistory.com)
To increase the accuracy of the results, and SNP overlaps between the customer and the calculator population references, only genomes with the highest average read depth coverage were carefully chosen to source the component allele frequencies. (geneplaza.com)

It was much like studying "fossil" DNA imprinted within the genome. (popular-archaeology.com)
When he died in 2003, the Bernard Price Institute housed one of the largest fossil collections in the southern hemisphere. (asu.edu)
As new fossil remains emerge from China and south-east Asia, the traditional story of how we left Africa is being challenged. (pearltrees.com)

Compared to elsewhere, especially Europe, there has been little genomic investigation of ancient African peoples. (nature.com)
The urban peoples of the Swahili coast traded across eastern Africa and the Indian Ocean and were among the first practitioners of Islam among sub-Saharan people1,2. (bvsalud.org)

Organisms1

Diseases2

Chemicals and Drugs1

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes11

Information Science2

Named Groups2

Geographicals10

South Africa7

Populations33

North Africa1

200,000 years ago3

20172

Hunter-gatherers8

55,000 years ago2

Entire genomes2

Scientists5

Sequence3

60,000 years ago2

Migrations3

Researchers analysed1

Anatomically2

MtDNA1

Divergence2

Homo5

2,000 years ago1

Ancestry10

Schlebusch1

Mitochondrial DNA4

Late Pleistocene2

Extinct4

Hypothesis3

Sequences1

Archaic2

Ancestors6

Years19

Lineages1

Europeans2

Levant2

Genomics5

Continent4

Dispersals2

20231

Americas2

Study7

Species9

Prehistoric1

Modern6

Horn2

Time3

Oceania1

Patterns1

People5

Siberia1

Greatly1

Diversity2

ADNA2

Hominin1

Eurasia1

Geographical1

Found3

Population4

Fossil3

Peoples2