Somatic mutant apc proteins tumor suppressor proteins. Medical search. Frequent questions

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Anatomy15

Cell Line, Tumor Tumor Cells, Cultured Cell Line HeLa Cells Cells, Cultured Fibroblasts Cell Nucleus HCT116 Cells COS Cells Cell Line, Transformed Cytoplasm NIH 3T3 Cells HEK293 Cells Epithelial Cells 3T3 Cells

Organisms11

Mice, Knockout Mice, Inbred C57BL Mice, Nude Mice, Transgenic Mice, Inbred BALB C Mice, Mutant Strains Escherichia coli Drosophila Papillomaviridae Adenoviridae Cercopithecus aethiops

Diseases30

Adenomatous Polyposis Coli Cell Transformation, Neoplastic Adenoma Colonic Neoplasms Neoplasms Kidney Neoplasms Breast Neoplasms Wilms Tumor Osteosarcoma Neoplasms, Experimental Carcinoma, Renal Cell Neurofibromatosis 2 Adenocarcinoma von Hippel-Lindau Disease Liver Neoplasms Brain Neoplasms Skin Neoplasms Carcinoma, Hepatocellular Carcinoma, Squamous Cell Retinoblastoma Lung Neoplasms Neoplasm Metastasis Disease Progression Carcinoid Tumor Glioblastoma Disease Models, Animal Mammary Neoplasms, Experimental Ovarian Neoplasms Neovascularization, Pathologic Neuroendocrine Tumors

Chemicals and Drugs93

Adenomatous Polyposis Coli Protein Tumor Suppressor Protein p53 Tumor Suppressor Proteins beta Catenin Cytoskeletal Proteins Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF Retinoblastoma Protein Proto-Oncogene Proteins c-mdm2 Trans-Activators Bisbenzimidazole Nuclear Proteins Armadillo Domain Proteins DNA-Binding Proteins Transcription Factors Neurofibromin 2 Ubiquitin-Protein Ligases Cell Cycle Proteins Proto-Oncogene Proteins Cyclin-Dependent Kinase Inhibitor p16 PTEN Phosphohydrolase Cyclin-Dependent Kinase Inhibitor p21 Ligases Repressor Proteins RNA, Messenger Neoplasm Proteins Cyclins Proteins E2F Transcription Factors Recombinant Fusion Proteins Carrier Proteins Tumor Markers, Biological Protein-Serine-Threonine Kinases E2F1 Transcription Factor DNA Primers Suppressor of Cytokine Signaling Proteins RNA, Small Interfering Transcription Factor DP1 Oncogene Proteins, Viral Membrane Proteins Papillomavirus E7 Proteins WT1 Proteins Retinoblastoma-Binding Protein 1 Proteasome Endopeptidase Complex Retinoblastoma-Like Protein p107 DNA Tumor Necrosis Factor-alpha DNA, Neoplasm Ubiquitin Mutant Proteins Hypoxia-Inducible Factor 1, alpha Subunit Intracellular Signaling Peptides and Proteins Drosophila Proteins Cyclin-Dependent Kinases Phosphoric Monoester Hydrolases Phosphoproteins Antigens, Polyomavirus Transforming Recombinant Proteins Retinoblastoma-Like Protein p130 Apoptosis Regulatory Proteins Adaptor Proteins, Signal Transducing Ubiquitins Neurofibromin 1 DNA, Complementary Adenovirus E1A Proteins BRCA1 Protein Luciferases Adenovirus E1B Proteins Protein Isoforms Proto-Oncogene Proteins c-myc Serine Antineoplastic Agents Adenovirus E4 Proteins Cyclin-Dependent Kinase 4 Suppressor Factors, Immunologic MicroRNAs RNA, Neoplasm Oncogene Proteins Cyclin-Dependent Kinase Inhibitor p27 Hypoxia-Inducible Factor 1 Proto-Oncogene Proteins c-bcl-2 Multienzyme Complexes Cysteine Endopeptidases Protein Kinases Multiprotein Complexes Proto-Oncogene Proteins c-akt Cyclin D1 Enzyme Inhibitors Cyclin-Dependent Kinase 2 Cadherins Glutathione Transferase bcl-2-Associated X Protein Homeodomain Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Transfection Blotting, Western Reverse Transcriptase Polymerase Chain Reaction Tumor Burden Models, Biological Immunohistochemistry Polymerase Chain Reaction Mutagenesis, Site-Directed Precipitin Tests Immunoblotting Cloning, Molecular Immunoprecipitation Neoplasms, Experimental Transplantation, Heterologous Chromosome Mapping DNA Mutational Analysis Two-Hybrid System Techniques Gene Expression Profiling Microscopy, Fluorescence Flow Cytometry Models, Molecular Sequence Alignment Genetic Complementation Test Neoplasm Transplantation Fluorescent Antibody Technique Chromatin Immunoprecipitation Oligonucleotide Array Sequence Analysis Disease Models, Animal Amino Acid Substitution Mammary Neoplasms, Experimental Xenograft Model Antitumor Assays Blotting, Northern

Phenomena and Processes74

Genes, APC Genes, Tumor Suppressor Mutation Genes, MCC Protein Binding Genes, p53 Apoptosis Transfection Gene Expression Regulation, Neoplastic Amino Acid Sequence Cell Cycle Base Sequence Signal Transduction Genes, Suppressor Promoter Regions, Genetic Phosphorylation Transcription, Genetic Cell Proliferation Protein Structure, Tertiary Cell Division DNA Damage Binding Sites Transcriptional Activation Down-Regulation Gene Deletion Suppression, Genetic Phenotype Gene Silencing RNA Interference Loss of Heterozygosity DNA Methylation Gene Expression Regulation Sequence Homology, Amino Acid G1 Phase Plasmids Ultraviolet Rays Cell Aging Gene Expression Genes, Retinoblastoma Cell Survival Genes, Neurofibromatosis 2 Alleles Point Mutation Sequence Deletion Oncogenes Ubiquitination Time Factors Genes, Reporter Up-Regulation Cell Movement Genes, ras Cell Differentiation Amino Acid Motifs Genes, p16 Protein Transport Mutation, Missense S Phase Acetylation DNA Repair Protein Stability Exons Mitosis Active Transport, Cell Nucleus Gamma Rays Genetic Vectors Protein Processing, Post-Translational Kinetics Genes, Wilms Tumor Protein Conformation Amino Acid Substitution Enzyme Activation Tumor Microenvironment CpG Islands Mutagenesis

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Adenomatous Polyposis Coli Protein Genes, APC Tumor Suppressor Protein p53 Adenomatous Polyposis Coli Tumor Suppressor Proteins Genes, Tumor Suppressor beta Catenin Cytoskeletal Proteins Mutation Von Hippel-Lindau Tumor Suppressor Protein Genes, MCC Tumor Suppressor Protein p14ARF Retinoblastoma Protein Molecular Sequence Data Cell Line, Tumor Proto-Oncogene Proteins c-mdm2 Protein Binding Trans-Activators Bisbenzimidazole Tumor Cells, Cultured Nuclear Proteins Armadillo Domain Proteins Genes, p53 Cell Line DNA-Binding Proteins Apoptosis Transfection Transcription Factors Gene Expression Regulation, Neoplastic Neurofibromin 2 Amino Acid Sequence Cell Cycle Ubiquitin-Protein Ligases Base Sequence Signal Transduction Cell Cycle Proteins Genes, Suppressor Proto-Oncogene Proteins Promoter Regions, Genetic Cyclin-Dependent Kinase Inhibitor p16 PTEN Phosphohydrolase Cell Transformation, Neoplastic Cyclin-Dependent Kinase Inhibitor p21 Phosphorylation Transcription, Genetic Cell Proliferation Adenoma Ligases Protein Structure, Tertiary Cell Division DNA Damage Colonic Neoplasms Repressor Proteins RNA, Messenger Neoplasm Proteins Cyclins Neoplasms Binding Sites Blotting, Western Transcriptional Activation Proteins E2F Transcription Factors Down-Regulation Gene Deletion Suppression, Genetic Recombinant Fusion Proteins Carrier Proteins Tumor Markers, Biological Protein-Serine-Threonine Kinases Phenotype Gene Silencing HeLa Cells Cells, Cultured E2F1 Transcription Factor Reverse Transcriptase Polymerase Chain Reaction RNA Interference Fibroblasts DNA Primers Loss of Heterozygosity DNA Methylation Cell Nucleus Suppressor of Cytokine Signaling Proteins RNA, Small Interfering Transcription Factor DP1 Oncogene Proteins, Viral Membrane Proteins Kidney Neoplasms Papillomavirus E7 Proteins Gene Expression Regulation WT1 Proteins Retinoblastoma-Binding Protein 1 Tumor Burden Models, Biological Mice, Knockout Immunohistochemistry Proteasome Endopeptidase Complex Retinoblastoma-Like Protein p107 Mice, Inbred C57BL Sequence Homology, Amino Acid DNA

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