• A steep upturn at low angles dominates the small angle neutron scattering profile of low ionic strength polyelectrolyte solutions when measurements are extended to low angles not typical of most studies. (nist.gov)
  • Title : Ferromagnetic nanoparticles with peroxidase-like activity enhance the cleavage of biological macromolecules for biofilm elimination Personal Author(s) : Gao, Lizeng;Giglio, Krista M.;Nelson, Jacquelyn L.;Sondermann, Holger;Travis, Alexander J. (cdc.gov)
  • Structure of biological macromolecules. (uu.se)
  • Methods to study interactions between biological macromolecules. (uu.se)
  • Similar behaviour was found for confined water in various biological and non-biological environments, and a range of 18 solutions including low molecular weight organic glass formers, polymers, sugars as well as protein and DNA probed with broad band dielectric spectroscopy (see Box) between 10 -2 and 10 7 Hz [5]. (i-sis.org.uk)
  • Solution Properties and Potential Biological Applications of Zwitterionic Poly(epsilon-N-methacryloyl-L-lysine). (mpg.de)
  • His specialty is nuclear magnetic resonance (NMR) spectroscopy with biological macromolecules in solution. (scripps.edu)
  • Mrevlishvili and Svintradze (2005a, b) is demonstrated that one example of biological important and molecular self-assembly complex system is the collagen-DNA ordered aggregate which is spontaneously formed in aqueous solution. (scialert.net)
  • The research activities of the CSB revolve around three major biophysical approaches for studying the structure and dynamics of complex biological macromolecules: NMR spectroscopy, X-ray crystallography, and electron cryo-microscopy. (stonybrook.edu)
  • I am interested in studying rheological properties polymers and biopolymers and applying mathematical techniques, statistical mechanics and molecular modeling to study the properties of biological and synthetic macromolecules. (cmich.edu)
  • Biological macromolecules function in highly crowded cellular environments. (elifesciences.org)
  • provided a biological motivation for studying the effects of This task is further complicated by the background of abun- nominally inert background macromolecules on protein as- dant macromolecular crowding agent. (lu.se)
  • The Malvern mico V Dynamic Light Scattering instrument evaluates the hydrodynamic radius of macromolecules and macromolecular complexes in solution. (utmb.edu)
  • In the presence of high concentrations of inert macromolecules, the self-association of proteins is strongly enhanced through an entropic, excluded-volume effect variously called macromolecular crowding or depletion attraction. (lu.se)
  • The helix reversal is a structural motif found in helical polymers in the solid state, but whose existence is elusive in solution. (nature.com)
  • The key features of our experiments reside (i) in the nature of the polymers studied, since PFS BCPs enable a high level of control over the dimensions of core-crystalline micelles formed in solution, and (ii) in the size of the seed crystallites we examine. (nature.com)
  • For the polymers described herein this means that (counter-intuitively) the copolymer dissolve more rapidly in cold water (or saline solution) (4-10 °C). Do not heat to dissolve. (sigmaaldrich.com)
  • With an adequate MSD and CDF analyses, a multiple-mode diffusion of the cyclic and dicyclic polymers in the melt and semi-dilute solution of the linear polymer chains has been revealed, 14-16 suggesting the significant effects of the topological states of the polymers on the diffusive motion of the chains under entangled conditions. (jove.com)
  • Tetrathiahexacene as Building Block for Solution-Processable Semiconducting Polymers: Exploring the Monomer Size Limit. (mpg.de)
  • Allows a better characterisation of synthetic and natural polymers and proteins in solution. (lu.se)
  • In terms of number of molecules, water far outnumbers all other chemical species - ions, small organic molecules and macromolecules - added together. (i-sis.org.uk)
  • Solution behavior of double-hydrophilic block copolymers in dilute aqueous solution. (mpg.de)
  • Chiral Studies Across the Spectrum of Polymer Science: From dilute solution to the glassy state, from liquid crystals to peptide nucleic acids, to viruses and most recently investigations of plant based method of control of arthropod disease vectors. (nyu.edu)
  • Factors that control thermogelation in amphiphilic block copolymers include molecular weight of block segments, chemical composition of blocks, polymer concentration in solution and end group functionality. (sigmaaldrich.com)
  • Solution molecular biophysics and thermodynamic techniques are used both as a primary research tool as well as means to structural studies (for example in the exploration of conditions for crystallization of proteins). (utmb.edu)
  • NEB has a long history in recombinant protein expression and has developed a wide array of solutions for proteins that are difficult to express. (neb.com)
  • Thanks for holding, and welcome to the New England BioLabs Solutions for the Expression of Difficult Proteins conference call. (neb.com)
  • Welcome to everyone who has chosen to join us for this information session on solutions for the expression of difficult proteins. (neb.com)
  • I will start by outlining the most common problems encountered during the expression of recombinant proteins in E. coli and specific solutions will be given for each problem. (neb.com)
  • As a solution NEB offers a tunable T7 expression strain for the production of membrane proteins and other difficult targets so that the level of functional protein may be optimized. (neb.com)
  • NEB also offers solutions for expressing these types of proteins, either in vitro or in vivo. (neb.com)
  • In the bloodstream, drugs are transported partly in solution as free (unbound) drug and partly reversibly bound to blood components (eg, plasma proteins, blood cells). (msdmanuals.com)
  • Solutions of macromolecules exhibit viscoelastic properties and unlike Newtonian fluids, they may break time-reversal symmetry at low Reynolds numbers resulting in elastic turbulence. (lu.se)
  • In CONCERT we will develop a method based on the use of nuclear magnetic resonance spectroscopy in solution that will provide very detailed descriptions of such changes by using the information about structural heterogeneity contained in a parameter that is exquisitely sensitive to molecular shape called residual dipolar coupling measured in steric alignment. (europa.eu)
  • Addition of inert macromolecules to a protein solution quantitatively the self-association of bovine pancreatic shifts equilibria toward the more compact state because this trypsin inhibitor (BPTI) (Gottschalk et al. (lu.se)
  • Her current research focuses on the properties of concentrated protein solutions with a particular interest in protein dynamics under crowded conditions. (lu.se)
  • PACT Premier and JCSG+) conducted at two temperatures (typically 20°C and 4°C). A typical drop size consists of 100 nl of protein and 100 nl of precipitant solution. (lu.se)
  • It can also be used to observe protein structure in dynamics and solution, and to determine the averaged particle size, shape, and distribution, as well as surface-to-volume ratio. (lu.se)
  • The product may also be a protein or other macromolecule such as a modified carbohydrate or biopolyester. (lu.se)
  • Alfrey, T., Bartovics, A. and Mark, H. (1942) The Effect of Temperature and Solvent Type on the Intrinsic Viscosity of High Polymer Solutions. (scirp.org)
  • Transport properties (diffusivities, self -assembly and the intrinsic viscosities) of macromolecules using computational techniques. (cmich.edu)
  • through a redox reaction which is capable of pathophysiological darkening of the tooth breaking down the macromolecules responsible for (intrinsic), trauma, iatrogenic endodontic treatment pigmentation, promoting a whitening effect (LIMA and extrinsic stains from enamel/dentine et al. (bvsalud.org)
  • SE experiments is one of the best ways for determining the molecular weights of macromolecules and excellent for analysis of heterogeneity in solution. (utmb.edu)
  • The present study demonstrated the one example of biologically important and molecular self-assembly system is a collagen-DNA ordered aggregates which spontaneously forms in aqueous solution. (scialert.net)
  • In this paper is demonstrated that one example of the biologically important and molecular self-assembling complex system is a collagen-DNA ordered aggregates spontaneously formed in aqueous solutions. (scialert.net)
  • According to the molecular model (Mrevlishvili and Svintradze, 2005b) DNA containing well-arranged phosphate groups helps to make this complex and these groups and water layers play key roles during collagen-DNA ordered aggregation in aqueous solution. (scialert.net)
  • The rapid and impressive advancements in chemical biology during the last decade have clearly demonstrated that solutions for a vast majority of medical problems rely on the understanding of the molecular basis of diseases, therapeutic targets, drug actions, and drug resistance. (stonybrook.edu)
  • This behavior is consistent with static and dynamic light scattering measurements performed on the same solutions. (nist.gov)
  • Furthermore, and analogously to aqueous solutions, different water isotopes (H2O/D2O) and salt additives were found to affect the phase transition as well. (wikipedia.org)
  • Also, because the properties of surfactants in concrete and their properties in aqueous solutions often differ significantly, the compatibility of surfactants and cement particles is an essential factor determining the performance of foamed concrete. (cie-china.org)
  • AWS Health Data Portfolio aligns purpose-built AWS Services and AWS Partner solutions to business needs, ranging from secure data transfer, aggregation, and storage to data analytics, collaboration, sharing, and governance. (amazon.com)
  • Almost all polysulfobetaines are insoluble in water at low temperatures, however many polysulfobetaines feature an upper critical solution temperature (UCST) in aqueous solution. (wikipedia.org)
  • For this purpose, we designed seed trapping experiments in solution that gave us information about the dissolution of polymer crystals as function of temperature. (nature.com)
  • Thermogelation is a temperature triggered reversible solution-to-gel phase transition phenomenon. (sigmaaldrich.com)
  • Alternatively, therapeutic agents can be added directly to the aqueous polymer solution and then physically entrapped in the PLGA hydrophobic segments which form physical crosslinks as the temperature of the solution increases and the hydrogen bonding effect of the PEG is decreased limiting its solubility. (sigmaaldrich.com)
  • Temperature sweep rheometry experiments are utilized to obtain sol-gel curves in order to validate gelation properties of polymer solutions with and without incorporated therapeutic agents. (sigmaaldrich.com)
  • For instance, we developed innovative solutions to improve the encapsulation of flowing particles using viscoelastic flows in microfluidic devices, and we also developed microfluidic techniques to evaluate rheological parameters not measurable via conventional techniques. (swansea.ac.uk)
  • The X-ray facility has the latest robots and imaging equipment for preparing crystals of macromolecules. (stonybrook.edu)
  • It is well known that enzymes and other macromolecules, DNA and RNA, need a minimum amount of water in order to work at all, and much more to work efficiently. (i-sis.org.uk)
  • The reason for the UCST-type behavior of polysulfobetaines in solution is based on their electrically neutral behavior, i.e., the overall charge is zero, over a large pH range (approximately 2 - 14). (wikipedia.org)
  • Transforming biobased resources into the desired products requires customized processes and technological solutions. (lu.se)
  • The Keck NMR Center for Structural Biology houses four NMR spectrometers: standard bore 700 MHz and 850 MHz spectrometers for solution NMR studies and wide bore 500 MHz and 600 MHz spectrometers for solid-state NMR studies. (stonybrook.edu)
  • 131, In press, (1998) +} {+ reference: Clore GM, Gronenborn AM, Bax A, A robust method for determining the magnitude of the fully asymmetric alignment tensor of oriented macromolecules in the absence of structural information. (lu.se)
  • The presence of salt additives in aqueous solution leads to an altered balance of the attractive and repulsive interactions and therefore, also to an altered solubility. (wikipedia.org)
  • 7000 Da), but also offered new insights into the iterative synthesis of sequence-defined macromolecules in general, as we present a detailed comparative study of the same chemistry protocols carried out on solid phase as well as in solution. (rsc.org)
  • The synthesis of perfectly defined, monodisperse macromolecules is one of the challenges faced by polymer chemists today. (rsc.org)
  • ICB&DD promotes highly productive interdisciplinary and collaborative research among chemists, biologists, medicinal chemists, pharmacologists, and physicians to attack major biomedical problems to find solutions including the discovery of novel therapeutic drugs. (stonybrook.edu)
  • Dissolution can be in either water or saline solution, or mixtures with other ingredients. (sigmaaldrich.com)
  • Analytical ultracentrifugation studies of cytochrome p450 orthologues led to the successful crystallization and structure solution of the first open-form of a p450 ( 1 ). (utmb.edu)
  • 4(6), 443-9, (1997) June +} {+ reference: Tjandra N, Omichinski JG, Gronenborn AM, Clore GM, Bax A, Use of dipolar 1H-15N and 1H-13C couplings in the structure determination of magnetically oriented macromolecules in solution. (lu.se)
  • SV experiments leads to the determination of the sedimentation coefficient, s, which can provide information about the shape and molar mass of macromolecules in solution, as well as their size-distribution. (utmb.edu)
  • The best method to transfer to a new container is to dissolve in the original packaging (e.g. adding 5 mL of saline to ~1 g triblock would yield a 20 % solution) and then transfer the solution of known concentration. (sigmaaldrich.com)
  • The purpose of the lab is to enhance solution biophysics research of SCSBMB core faculty members and UTMB collaborators. (utmb.edu)
  • Besides teaching, Khorolskyi does research on macromolecules. (aps.org)
  • He served for three years on the editorial board of the American Chemical Society journal, Macromolecules and he serves on the editorial board of Topics in Stereochemistry. (nyu.edu)
  • We study macro to micro to nanosuspension (solution and melt) rheology. (cmich.edu)
  • Dithieno[2,3-d;2 ',3 '-d ']benzo[1,2-b;4,5-b ']dithiophene (DTBDT) as Semiconductor for High-Performance, Solution-Processed Organic Field-Effect Transistors. (mpg.de)
  • Interestingly, polysulfobetaine thin films feature a cononsolvency effect in mixed water/methanol vapors, which is not found in water/methanol solution. (wikipedia.org)
  • Water is needed for macromolecules to become flexible, so they can dance freely to water's quantum jazz, in order to accomplish their otherwise impossible tasks of making sluggish chemical reactions happen spontaneously and effortlessly. (i-sis.org.uk)
  • Stony Brook students use the macromolecule beam lines at NSLS-II, a recently completed synchrotron light source at Brookhaven National Laboratory. (stonybrook.edu)
  • Students will be able to concretely illustrate and define a macromolecule. (juliantrubin.com)
  • Students will define crosslink and make crosslinked polymer solutions. (juliantrubin.com)
  • Students will need several 50-ml cups and sufficient amounts of solutions. (juliantrubin.com)
  • Herein, we have shown how the photochemical electrocyclization (PEC) of poly(phenylacetylene)s (PPAs) can be used to determine not only the presence of helix reversals in polymer solution, but also to estimate the screw sense excess. (nature.com)
  • In controlled release drug delivery the polymer is combined with a therapeutic agent in the solution state and injected into the tissue target. (sigmaaldrich.com)
  • Benzo[1,2-b: 4,5-b ']bis[b]benzothiophene as solution processible organic semiconductor for field-effect transistors. (mpg.de)
  • The magnetic beads were used as scavengers in the preparation of sulphonamides and were removed from solution with a small array of magnets. (ddw-online.com)