• Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. (abcam.com)
  • Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. (abcam.com)
  • By using two syngeneic monoclonal antibodies against the soluble melanoma antigens (M2590 and M562), we found that the melanoma antigen was composed of GM3 (NeuAc) in association of proteins. (go.jp)
  • A much more promising strategy is to use recombinant monoclonal antibodies (mAbs) against influenza and several are currently in clinical development ( 9 - 13 ). (frontiersin.org)
  • For the last two decades, our understanding of immunology exploded with the advent of technologies that allowed high throughput screening and generation of large molecule biologics such as monoclonal antibodies (mAb) and small molecule compounds. (frontiersin.org)
  • Similar to the human MAbs 2909, PG9, and PG16, these rhesus macaque monoclonal antibodies (RhMAbs) recognize QNEs that include the V2 and V3 loops. (woofahs.com)
  • Monoclonal antibodies are used to detect serum antigens associated with specific malignancies. (aafp.org)
  • These soluble molecules in the blood are usually glycoproteins detected by monoclonal antibodies. (aafp.org)
  • In this study, we obtained 14 high-titer and high-specificity monoclonal antibodies, and the test strips exclusively react with the SARS-CoV-2-N protein and no cross-reactivity with other coronavirus and also recognize the recombinant N protein of Delta (B.1.617.2) variant. (pimac.org)
  • Therapeutic monoclonal antibodies (MAbs) have been found to be highly effective agents in the treatment of immunological disorders with a high level of success due to their structural specificity and low toxicity. (lu.se)
  • See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more. (lsbio.com)
  • Cytotoxic T lymphocytes or helper T cells involved in the positive immune responses were easily induced by the antigen on the cell surface, whereas soluble melanoma antigens secreted into the culture medium selectively stimulate and induce antigen-specific suppressor T cells. (go.jp)
  • Furthermore, the soluble antigen works as an inhibitor for the blocking of the cytotoxic T cell activity. (go.jp)
  • Therefore, the soluble melanoma antigen stimulates the negative immune response in order for tumor cells to escape from immune system. (go.jp)
  • The first was concerned with the rate and amount of excretion of soluble ^(35)S-labeled hemocyanin (KLH) and bovine serum albumin (BSA) following a single intravenous injection into normal rabbits and also with the properties of the excreted antigen material and its possible association with ribonucleic acid (RNA) or nucleotides. (caltech.edu)
  • The presence of dinitrophenyl groups on the immunizing antigen could suppress, partially or completely, the antibody response to p-azophenyl arsonate when this hapten was located on the same molecule. (caltech.edu)
  • These findings appear irreconcilable with the possibility of direct clonal selection of antibody-producing cells by unprocessed antigen. (caltech.edu)
  • The purpose of the present investigation was to study further, such antibody which appeared to be bound with antigen and perhaps normal tissue constituents. (caltech.edu)
  • After varying lengths of time, when circulating antibody had declined, antigen was again injected. (caltech.edu)
  • The specific activity of antibody was measured in the antigen-antibody precipitates obtained, both in the period when the antibody had been allowed to decline and also after antigen had been reinjected to induce an anamnestic response. (caltech.edu)
  • The biological activity of soluble antigen-antibody complexes: II. (caltech.edu)
  • 2), and ourselves (3) has established the fact that soluble antigen-antibody complexes formed in excess antigen can, (a) induce symptoms similar to anaphylaxis, (b) cause contraction of isolated smooth muscle from normal guinea pigs, and (c) increase the permeability of skin capillaries in a manner similar to that obtained in passive cutaneous anaphylaxis. (caltech.edu)
  • Passively administered homologous antibody did not produce a change in the retention of the primary injection of antigen nor did secondary injections of a heterologous native protein injected according to the same immunization schedule as the homologous azoprotein. (caltech.edu)
  • From these results it may be concluded that an intracellular antibody-forming activity influences the loss (or retention) of antigen deposited in liver tissue and that the mechanism is immunologically specific. (caltech.edu)
  • 1) The general approach has been to attempt to produce an insoluble protein antigen which would combine specifically with antibody to give a complex that could be dissociated into soluble antibody and insoluble antigen, which could then be separated by centrifugation. (caltech.edu)
  • However, in every case the resulting product either had lost too much native antigenicity (i.e., adsorbed serum always contained antibody which reacted with native antigen), was too soluble, or had too much power of adsorption for non-specific protein. (caltech.edu)
  • Single domain antibody (sdAb), also called nanobodies, is the variable region isolated from the antigen-binding variable domain (VHH) of camel heavy-chain only antibody or the variable domain (vNAR) of cartilaginous fish immunoglobulin new antigen receptor (IgNAR). (antibodyproduction.co.uk)
  • Single Domain Antibody (sdAb) is the smallest known antigen-binding fragment. (antibodyproduction.co.uk)
  • codon optimization and soluble protein expression available for antigen production. (biologicscorp.com)
  • Antigen affinity purification: obtain polyclonal antibody with high titer and specificity. (biologicscorp.com)
  • Infection status was also determined by the CCA-ICT and infection exposure by antibody ELISA (enzyme-linked immunosorbent assay) to S. mansoni soluble egg antigen (SEA) and soluble (adult) worm antigen preparation (SWAP). (gwu.edu)
  • With the exception of prostate-specific antigen (PSA), tumor markers do not have sufficient sensitivity or specificity for use in screening. (aafp.org)
  • Cancer antigen (CA) 27.29 is a monoclonal antibody to a glycoprotein (MUC1) that is present on the apical surface of normal epithelial cells. (aafp.org)
  • This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. (thermofisher.com)
  • The sensitivity and specificity of the antibodies were evaluated by enzyme-linked immunosorbent assay and immunohistochemistry. (hindawi.com)
  • Our work was the first revelation that a "noisy" nanopore sensor could not only discriminate among homologous proteins but could maintain this sensitivity and specificity in a serum sample. (umass.edu)
  • Sensitivity and specificity were influenced by whether the trace score visually adjudicated in the CCA-ICT was characterized as positive or negative for S. mansoni infection. (gwu.edu)
  • High sensitivity and specificity of sCD40L was observed compared to AFP (90%, 86.7% and 83% and 80% respectively). (who.int)
  • The sensitivity and specificity of such testing can now be improved as a result of the recent discovery of the Cystic Fibrosis Transmembrane Conductance Regulatory (CFTR) gene. (cdc.gov)
  • The discovery of the Cystic Fibrosis Transmembrane Conductance Regulatory (CFTR) gene (5) renewed interest in this possibility, as the sensitivity and specificity of testing could be improved through DNA-based testing. (cdc.gov)
  • In conclution, DNA amplification is a rapid, reliable and accurate method with a high degree of sensitivity and specificity for the detection of Mycobacterium tuberculosis DNA sequences and it can replace the conventional culture method in the diagnosis of extra pulmonary tuberculosis and tuberculosis meningitis except in the situation when antibiotic sensitivity results are required. (who.int)
  • When a person or test animal (e.g., a mouse) is inoculated with a particular type, an immune response ensues, generating antibodies that react specifically with antigens on the bacteria. (wikipedia.org)
  • The specificity of tissue antigens has previously been investigated by the usual immunologic procedures [1] and the effects of antibodies [2,3] upon tissue explants has long been known. (caltech.edu)
  • The problem of obtaining from precipitation experiments evidence about the structure of antibodies and the nature of serological reactions is obviously greatly simplified by the replacement of protein antigens by simple substances of known structure. (caltech.edu)
  • Polyclonal antibody (pAb) is obtained from different B-lymphocytes after reaction with corresponding antigens. (biologicscorp.com)
  • Recombinant targeting modules will be based on antibodies and soluble single-chain fragments of TCR specific for melanoma antigens. (unimedizin-mainz.de)
  • These authors recommended that the medical diagnosis of scientific mastitis cases could possibly be significantly enhanced if examples showing no development on culture mass media could be put through Birinapant (TL32711) an enzyme-linked immunosorbent assay (ELISA), due to the antibodies' noticed ability to identify soluble, aswell as insoluble, antigens, of intact bacterial cell existence in dairy independently. (rue2011.com)
  • Antinuclear antibody patterns at immunofluorescence, such as multiple nuclear dot and rim-like patterns [ 14 ] corresponding to gp210 and sp100 antigens on enzyme-linked immunosorbent assay, [ 9 ] may be helpful for diagnosis in AMA-negative patients, given their specificity for PBC. (medscape.com)
  • The immunofluorescence ANA assay (Antibodies, Inc) utilizes the method considered the gold standard for ANA testing by the American College of Rheumatology: detecting circulating autoantibodies reactive with nuclear antigens of HEp-2 cells. (nemours.org)
  • The ANCA assay (INOVA) detects the presence of IgG antibodies that bind to human neutrophil antigens using direct immunofluorescence.¹,² Screening all samples with ethanol fixed slides allows ANCA reactivity to be separated into two diagnostically useful categories. (nemours.org)
  • Abbkine secondary antibodies are available conjugated to enzyme, biotin or fluorophore for use in a variety of antibody-based applications including Western Blot, ImmunoHistoChemistry, ImmunoFluorescence, Flow Cytometry and ELISA. (abbkine.com)
  • Human IgG antibody Laboratories manufactures the soluble il-15ra elisa reagents distributed by Genprice. (influenza-x.org)
  • The Soluble Il-15Ra Elisa reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (influenza-x.org)
  • Description: A competitive ELISA for quantitative measurement of Rabbit Soluble IL 1 Receptor 4/ST2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. (influenza-x.org)
  • This format provides pure antibody that is suitable for a number of downstream applications including: secondary labeling for flow cytometry or microscopy, ELISA, Western blot, etc. (bdbiosciences.com)
  • A specific antibody titer of sera from mice immunized with mRBD was ten-fold higher than the sera from the mice that received pRBD in ELISA, and about 100-fold higher in a neutralization test. (pimac.org)
  • Describes the use of this antibody in a sandwich ELISA to detect amyloid protein. (absoluteantibody.com)
  • Blood serum containing the antibodies can then be extracted and applied to cultured bacteria. (wikipedia.org)
  • Passive transfer of serum antibodies from convalescent patients has been used in the past ( 7 , 8 ), however, this approach is of limited use in a global pandemic emergency. (frontiersin.org)
  • Serum samples were then taken at various intervals and the specific activity of antibody was measured as soon as antibody reappeared in the circulation. (caltech.edu)
  • Quantitative antibody nitrogen data, obtained for the serum of each rabbit showed, in general, an inverse relationship between circulating antibody and radioactivity retained, i.e. the higher the circulating antibody titer, the lower the retention of radioactivity in liver tissue. (caltech.edu)
  • In addition, the serum of patients with glomerular nephritis was found to contain a substance with similar effects and specificity. (caltech.edu)
  • Some success has been obtained also in the formation of antibodies from other serum proteins and by other denaturation-renaturation procedures. (caltech.edu)
  • Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles. (crbdiscovery.com)
  • Serum adsorbed secondary antibodies are also available and are recommended for use with immunoglobulin-rich samples. (abbkine.com)
  • We tested several sets of serum specimens: 104 specimens tested positive for T. cruzi specific antibody and 283 (including 30 specimens positive for antibody to Leishmania spp. (cdc.gov)
  • As stated in previous function [6], Traditional western blotting assays utilizing a polyclonal anti-GB streptococci antibody evidenced two stained immunogenic protein in cell wall structure protein pattern aside from the anticipated immunogenic protein group of strains may also react with Lancefield group B serum. (rue2011.com)
  • We suggest that close follow-up together with periodic endoscopic examination for all patients with persistent H. pylori infection and serum soluble E-cadherin level above 5 µg/mL is essential. (who.int)
  • T cells and TCR will be obtained from blood and tumor tissue and tested for neoantigen specificity and tumor reactivity. (unimedizin-mainz.de)
  • The high titer (1:32000) polyclonal antibodies with high specificity were obtained by immunizing rabbits with the purified recombinant protein. (hindawi.com)
  • If you are looking for large volume polyclonal antibody production, large animal such as goat or sheep can be used as host species to obtain enough polyclonal antibodies to meet your requirements. (biologicscorp.com)
  • The specificity of rabbit polyclonal antibodies to the LC3A and the LC3B was tested against the commercial available human recombinant proteins LC3A and LC3B. (ox.ac.uk)
  • There was no correlation between anti-TNP-precipitating antibody titer after sensitization and the ability to respond to challenge by hapten-heterologous carrier. (caltech.edu)
  • Proteins were visualized using a peroxidase-conjugated antibody to rabbit IgG and a chemiluminescence detection system. (enzolifesciences.com)
  • In addition, we found that OmpG could discriminate among eight target proteins, four avidin homologues and four antibody homologues. (umass.edu)
  • Newly produced antibody, like the other plasma proteins, became readily labelled with S35 amino acids within a few hours. (caltech.edu)
  • Further, when dealing with in vivo models it is necessary to check the specificity of the antibodies used against the LC3A and LC3B proteins as their expression and responsiveness is not overlapping. (ox.ac.uk)
  • Both methods yield antibody in solution that is free of most other soluble proteins, lipids, etc. (bdbiosciences.com)
  • TrSOD, TAT-TrSOD-Yfp (fused to yellow fluorescent protein) and Ab-TrSOD were expressed in E.coli and purified as soluble proteins. (pimac.org)
  • The antibodies had been likely to attach to proteins A of Nanomag? (rue2011.com)
  • Antibody BU63 recognizes the CD86 molecule of 80 kd (3). (ancell.com)
  • Recognizes soluble TRAIL. (enzolifesciences.com)
  • The human monoclonal antibody (MAb) 2909 recognizes a QNE present on the oligomeric Env spike present on the surface of HIV-1 SF162 virions (8). (woofahs.com)
  • [ 10 ] In general, these assays depend on an antibody that recognizes 25(OH)D2 and 25(OH)D3 in equimolar proportions and the competitive displacement of tracer 25(OH)D (25(OH)D that has been tagged with a radioactive isotope such as 125-I or a chemiluminescent ligand) by acetonitrile extracted samples. (medscape.com)
  • In this study, the cloning and expression of mouse IL-33 gene in Escherichia coli (E. coli ), purification of recombinant protein, and generation of polyclonal antibody against IL-33 are described. (hindawi.com)
  • The prepared antibody can be useful for the study of expression and distribution of IL-33 in various tissues at protein level and for the elucidation of its biofunctions and regulation mechanism in inflammatory diseases. (hindawi.com)
  • Antibody BU63 blocks MLR and blocks binding of soluble CD152-muIg fusion protein to CD86. (ancell.com)
  • M2590 recognized GM3 carbohydrate moiety with cross-species specificities, while M562 reacts with the protein with species specific melanoma antigenic determinant. (go.jp)
  • The histochemical antibody for Vesicular Monoamine Trnasporter 2 (VMAT2) is generated in a rabbit from a synthetic peptide corresponding to rat VMAT2 496-515 coupled to carrier protein. (newmarketscientific.com)
  • Yantai, China, May 15, 2023- Boan Biotech is to present the results of its research on BA1302, a novel CD228-directed antibody drug conjugate (ADC) developed by the company, as a poster at the 19th Essential Protein Engineering & Cell Therapy Summit, known as PEGS Boston Summit 2023 or simply PEGS Boston 2023. (boan-bio.com)
  • It is the leading biologics event with comprehensive programming covering all aspects of biologic drug development, including presentations on protein and antibody engineering, immunotherapy, oncology, expression, analytics, immunogenicity, and more. (boan-bio.com)
  • Fractionated samples (soluble vs. membrane fractions) should be used in immunoblotting to allow discrimination between the LC3-I soluble and the LC3-II membrane protein and kinetics. (ox.ac.uk)
  • Denosumab binds to RANKL, a transmembrane or soluble protein essential for the formation, function, and survival of osteoclasts, the cells responsible for bone resorption. (inceptapharma.com)
  • By selecting the best antibodies, you'll be able to perform immunological identification of Group B Streptococci (including immunogenic protein (Amount 1A,B). A polyclonal anti-GB Streptococci IgG (8435-2000, AbD Serotec, Kidlington, UK) and one monoclonal anti-IgM (MA1-10871, Thermo Fisher, Waltham, USA), had been used individually. (rue2011.com)
  • Soluble amyloid beta-protein in the cerebrospinal fluid from patients with Alzheimer's disease, vascular dementia and controls. (absoluteantibody.com)
  • Western Blot using anti-Amyloid beta antibody 6E10 (Ab00714) Human brain cerebral cortex (A), frontal cortex (B) and cerebellum (C) lysate samples (35µg protein in RIPA buffer) were resolved on a 10% SDS PAGE gel and blots probed with the chimeric rabbit version of 6E10 (Ab00714-23.0) at 0.3 µg/ml before detection using an anti-rabbit secondary antibody. (absoluteantibody.com)
  • Protein-protein interaction models have been used to study the solution structure of 5 MAbs and their protein-protein interactions at high concentrations under specific formulation conditions where they remain soluble. (lu.se)
  • It has higher binding specificity, and binds with the membrane form of CD228 only, not with sMF12, which is its soluble form. (boan-bio.com)
  • Description: IL-15RA Antibody: Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. (influenza-x.org)
  • The human sequence antibody specifically binds to human CTLA-4 or the CTLA-4 on the cell surface of normal human T cell. (creativebiolabs.net)
  • This antibody binds to amino acid residues 1-16 of beta amyloid. (absoluteantibody.com)
  • After washes with PBS, samples were incubated with a biotinylated secondary antibody to rabbit IgG for 1 hour, washed in PBS and revealed with StreptABComplex/HRP (Vector) and AEC. (enzolifesciences.com)
  • While investigating the pathogenesis of experimental nephritis produced by rabbit anti-rat-kidney antibody, it occurred to us that the effects of antikidney antibody on kidney tissue might readily be visualized in tissue cultures. (caltech.edu)
  • Rabbit antibodies are considered as the first choice in most polyclonal antibody productions. (biologicscorp.com)
  • We offer high quality secondary antibodies from goat, rabbit and donkey sources for your each application. (abbkine.com)
  • Immunohistochemical staining of human Alzheimer's disease hippocampus tissue using anti-Amyloid Beta antibody (Ab00714) 6E10 Anti-Amyloid Beta staining of paraffin embedded human hippocampus affected by Alzheimer's disease using the rabbit-chimeric version of 6E10 (Ab00714-23.0). (absoluteantibody.com)
  • Samples were then incubated with an anti-rabbit IgG HRP secondary antibody (Dako cat#K4009) for 20 mins followed by DAB (3,3′-diaminobenzidine), and counter-staining with haemotoxylin. (absoluteantibody.com)
  • The growth and function of tissue explants have previously been used to study the specificity of tissue antibodies [4,5], but the antisera used were of low, uncertain potency, and only a few different tissues were examined in testing the toxic effects. (caltech.edu)
  • Tissue staining is completely eliminated by pretreatment of the diluted antibody with an excess of rat VMAT2 peptide residues 496-515. (newmarketscientific.com)
  • Store undiluted at 4°C. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. (bdbiosciences.com)
  • This antibody recognises human amyloid beta and can be used to detect amyloid in ELISAs, WB and tissue sections. (absoluteantibody.com)
  • The purification procedure Avery undertook consisted of first killing the bacteria with heat and extracting the saline-soluble components. (wikipedia.org)
  • For the past several years we have been interested in devising methods that would afford practical procedures for the isolation and purification of antibodies from immune serums and in particular the isolation of non-precipitating antibodies from animal serums and allergic antibodies (reagins) from human serums. (caltech.edu)
  • We have previously described R1a-B6, an alpaca-derived single domain antibody (nanobody), that is capable of potent cross-subtype neutralization in vitro of H1N1, H5N1, H2N2, and H9N2 influenza viruses, through binding to a highly conserved epitope in the influenza hemagglutinin stem region. (frontiersin.org)
  • Jotbody (HK) Limited is a biotechnology company on the cutting edge of single-domain antibody discovery, production, and application. (antibodyproduction.co.uk)
  • Jotbody is dedicated to offering single-domain antibody discovery CRO services and single-domain antibody-based research reagents of outstanding quality to the global scientific community at unbeatable prices. (antibodyproduction.co.uk)
  • It reacts with free soluble (17 kDa) and membrane (26 kDa) human TNF-alpha. (abcam.com)
  • Reacts with soluble (17kD) and membrane (26kD) human TNF-alpha. (lsbio.com)
  • The antibody reacts with whole molecule mouse IgG. (abbkine.com)
  • The secreted soluble form of CTLA-4 (sCTLA-4) lacks the transmembrane domain as well as the membrane proximal cysteine residue required for covalent homodimerization and therefore sCTLA-4 is only present in monomeric form. (crbdiscovery.com)
  • 2. According to the recommended primary antibody dilution ratio, use the TBST Buffer containing 5% Skim Milk Powder to dilute the CD38 Antibody at , soak the PVDF Membrane in the primary antibody working solution, incubate overnight at 4 ℃, and gently shake. (elabscience.com)
  • The level may be too low for detection but still significant with respect to antibody formation. (caltech.edu)
  • Biologics Internation Corp (BIC) offers one-stop antibody production services and provides high quality pAb for qualitative immune-detection assays. (biologicscorp.com)
  • Prognosis relies on serological strategies with detection of particular IgG and IgM antibodies. (r-web.cz)
  • A molar saturation curve vs fluorescence intensity, antibody activity, background level, and/or other parameters has been established for each dye to optimize the level of antibody detection and minimize background). (abbkine.com)
  • Examination of direct smears for acid fast bacilli is the widely used method for the detection of mycobacteria, but lacks the desired specificity and relatively large number of bacteria is needed for detection. (who.int)
  • This antibody detects both natural and recombinant TNFa. (abcam.com)
  • These observations have led to the suggestion that IL-12 might have evolved from a cytokine/soluble receptor complex. (rndsystems.com)
  • Denosumab is a human IgG2 monoclonal antibody with affinity and specificity for human RANKL (receptor activator of nuclear factor kappa-B ligand). (inceptapharma.com)
  • Exists also as a soluble receptor. (lu.se)
  • Our findings demonstrate that a single intramuscular injection in mice of AAV encoding R1a-B6 fused to Fc fragments of different isotypes equipped either, with or without antibody dependent cellular cytotoxicity (ADCC) activity, was able to drive sustained high-level expression (0.5-1.1 mg/mL) in sera with no evidence of reduction for up to 6 months. (frontiersin.org)
  • Mediates antibody-dependent cellular cytotoxicity (adcc) and other antibody-dependent responses, such as phagocytosis. (lu.se)
  • Limiting dilutions of soluble H5 trimers complexed with horseradish peroxidase−conjugated antibodies were used in a fetuin- or transferrin-binding assay. (cdc.gov)
  • This study evaluated the diagnostic accuracy of a T solium cysticercosis antibody-detecting lateral-flow point-of-care assay (TS POC test) for the neuroimaging-based diagnosis of neurocysticercosis. (cdc.gov)
  • The in vitro toxicity of soluble oligomers is inhibited by oligomer-specific antibody. (nih.gov)
  • Since endotoxin may also affect the results of functional studies, we recommend the NA/LE (No Azide/Low Endotoxin) antibody format, if available, for in vitro and in vivo use. (bdbiosciences.com)
  • The quadrant markers for the bivariate dot plots were set based on the autofluorescence controls and verified using the recombinant cytokine blocking and unlabelled antibody blocking specificity controls. (bdbiosciences.com)
  • After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. (lsbio.com)
  • Primary antibody incubation with Ab00714-23.0 was carried out at 4 µg/ml for 30 minutes. (absoluteantibody.com)
  • Carbohydrate xenoantigens and xenoantibody epitope-specificity, the removal of xenoantibodies by plasmapheresis, and antibody neutralization using soluble saccharides, were all explored. (gu.se)
  • The UniCAR is only activated upon cross-linking through a soluble tumor-targeting module carrying the UniCAR binding epitope, thereby achieving highest tumor specificity. (unimedizin-mainz.de)
  • In some cases, these broad neutralizing antibody responses can be mapped to the CD4-binding site of Env while in most cases a single epitope specificity cannot be identified to recapitulate the neutralizing breadth of the corresponding plasma (1, 4, 14, 15, 23, 25). (woofahs.com)
  • Detailed analyses of the epitope specificities of broad plasma neutralizing antibody responses performed by several groups revealed the presence in HIV-positive (HIV+) plasmas of NAbs with as yet undefined epitope specificities (1, 15, 18, 23). (woofahs.com)
  • Consequently, we compared the fine epitope specificities of these RhMAbs to the epitope specificity of the human MAb 2909. (woofahs.com)
  • An isotype control should be used at the same concentration as the antibody of interest. (bdbiosciences.com)
  • Nous suggérons qu'un suivi attentif et un examen endoscopique régulier sont essentiels pour tous les patients atteints d'une infection à H. pylori persistante et présentant une concentration sérique de la E-cadhérine soluble supérieure à 5 µg/ml. (who.int)
  • Immunohistochemistry of paraffin-embedded Human colon using CD38 Polyclonal Antibody at dilution of 1:100 (40x lens). (elabscience.com)
  • HIV-1 infection typically elicits high levels of antibodies directed against the viral surface envelope (Env) glycoprotein, gp160. (woofahs.com)
  • Specificity of the antiserum was demonstrated by soluble pre-adsorption and Western blot. (newmarketscientific.com)
  • Fig.1.Western blot analysis of Arabidopsis, primary antibody (A01050) was diluted at 1:5000, secondary antibody: A23710. (abbkine.com)
  • Western blot analysis of extracts of Raji cells using CD38 Polyclonal Antibody at dilution of 1:1000. (elabscience.com)
  • Soluble oligomers have a unique distribution in human AD brain that is distinct from fibrillar amyloid. (nih.gov)
  • TNF Alpha antibody LS-B2123 is an unconjugated mouse monoclonal antibody to TNF Alpha from human. (lsbio.com)
  • Anti-TNF Alpha antibody IHC of human lung. (lsbio.com)
  • Cell Proliferation Induced by IL‑12 and Neutralization by Human IL‑12 Antibody. (rndsystems.com)
  • Proliferation elicited by Recombinant Human IL‑12 (1 ng/mL) is neutralized (green line) by increasing concentrations of Human IL‑12 Polyclonal Antibody (Catalog # AB-219-NA). (rndsystems.com)
  • Recombinant human soluble TRAIL (aa 95-281). (enzolifesciences.com)
  • Recombinant soluble TRAIL, and recombinant soluble FasL as negative control, were resolved by SDS-PAGE under reducing conditions, transferred to nitrocellulose and detected with PAb to TRAIL (human) (Prod. (enzolifesciences.com)
  • Isolated human CD4+ cells were stimulated with immobilized anti-human CD3 mouse antibody (UCHT1, Cat. (bdbiosciences.com)
  • No. 555329), soluble anti-human CD28 mouse antibody (CD28.2, Cat. (bdbiosciences.com)
  • No. 555348), fixed, permeabilized, and subsequently stained with 0.12 µg of PE-rat anti-human IL-3 antibody (PE-BVD3-1F9, Cat. (bdbiosciences.com)
  • Herein the antibody is useful for treating human diseases, infections and other conditions using these antibodies. (creativebiolabs.net)
  • Soluble oligomers are common to most amyloids and may represent the primary toxic species of amyloids, like the Abeta peptide in Alzheimer's disease (AD). (nih.gov)
  • Therefore, CD228 has high specificity in terms of expressing in tumors. (boan-bio.com)
  • It is possible that these undefined specificities include quaternary neutralizing epitopes (QNEs) and/or sugar molecules which coat the HIV Env spike expressed on the surface of viral particles. (woofahs.com)
  • and the optimal moles of dye per antibody). (abbkine.com)
  • Sodium azide may be removed by washing stained cells or plate-bound antibody or dialyzing soluble antibody in sodium azide-free buffer. (bdbiosciences.com)
  • Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. (abcam.com)
  • The fungal metabolite cyclosporin A (cyclosporine) [ 384 , 385 ] has a greater specificity for lymphoid T cells than other cells. (nanomedicine.com)
  • As a novel type of drug, ADC is like a biological missile that effectively attacks target cells through the precise delivery of a chemical toxin linked to an antibody. (boan-bio.com)
  • Patients receiving ABO-incompatible kidney grafts were shown to elicit an individual specific response regarding antibody class and subclass. (gu.se)
  • However, several recent reports have indicated that approximately 25% of HIV-1-infected, antiretroviral-na?ve patients develop broad cross-neutralizing antibody responses (5, 23, 26). (woofahs.com)
  • These tests also must have sufficient specificity to protect patients with false-positive results from unwarranted diagnostic evaluations. (aafp.org)
  • [ 4 ] The majority of patients (95%) will have circulating antimitochondrial antibodies (AMAs) that develop before the onset of clinical disease. (medscape.com)
  • L'étude portait sur 20 patients atteints d'un carcinome gastrique, 20 patients souffrant d'une gastrite à H. pylori et 20 personnes en tant que groupe témoin. (who.int)
  • RÉSUMÉ L'objectif de l'étude était d'évaler l'importance clinique du ligand de CD40 soluble (sCD40L) chez des patients atteints d'un carcinome hépatocellulaire (CHC) associé au virus de l'hépatite C (VHC). (who.int)
  • Les concentrations sériques de sCD40L circulant et d'interleukine 10 circulante ont été analysées à l'aide de la méthode immuno-enzymatique chez 30 patients positifs pour le VHC avec un CHC, chez 30 patients patients positifs pour le VHC avec une cirrhose du foie, et chez 30 volontaires d'âge correspondant en bonne santé avec des anticorps anti-VHC négatifs servant de groupe témoin. (who.int)
  • The following product was used in this experiment: alpha Synuclein Monoclonal Antibody (Syn 211) from Thermo Fisher Scientific, catalog # AHB0261, RRID AB_2536241. (thermofisher.com)
  • We obtained six nanobodies with a broad specificity, that recognize strains belonging to the two most relevant species, Campylobacter jejuni and Campylobacter coli . (biomedcentral.com)