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  • type
  • Given that leptin requires 6 h to increase muscle glucose uptake, the transient activation of the MEK-ERK pathway in the VMH by leptin may play a role in the induction of synaptic plasticity in the VMH, resulting in the enhancement of MCR signaling in the nucleus and leading to an increase in insulin sensitivity in red-type muscle. (diabetesjournals.org)
  • Role
  • The nucleus of the solitary tract (NST), located in the dorsal medulla, plays a critical role in the autonomic regulation of a variety of homeostatic functions, such as heart rate, respiration, blood pressure, blood flow, and gastrointestinal motility. (jneurosci.org)