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  • Aqueous
  • The principle of solid phase extraction: an aqueous sample (e.g. fruit juice, wine or body fluid) is passed through a conditioned and equilibrated SPE cartridge, washed, dried and finally eluted with a small volume of organic solvent for further measurement. (bruker.com)
  • The humic and fulvic acids are extracted as a colloidal sol from soil and other solid phase sources into a strongly basic aqueous solution of sodium hydroxide or potassium hydroxide. (wikipedia.org)
  • Conventional
  • Conventional solid phase extraction techniques have utilized surfaces which either (1) fail to attract and hold sufficient quantities of DNA molecules because of surface design to permit easy recovery of the DNA molecules during elution, or (2) excessively adhere DNA molecules to the surface, thereby hindering recovery of the DNA molecules during elution. (google.com)
  • Matching extraction workflows demonstrated a reduction in carryover from 65% for conventional MEPS to only 1% for CDF-MEPS. (edu.au)
  • Extraction performance was compared with conventional polymer particulate adsorbents. (edu.au)
  • selective
  • Reversed-phase SPE is considered the least selective retention mechanism when compared to normalphase or ion-exchange SPE. (sigmaaldrich.com)
  • General pharmacological principles of metoprolol:[citation needed] beta-1 selective moderately lipophilic without intrinsic sympathomimetic activity with weak membrane stabilizing activity decreases heart rate, contractility, and cardiac output, therefore decreasing blood pressure Metoprolol blocks β1 adrenergic receptors in heart muscle cells, thereby decreasing the slope of phase 4 in the nodal action potential (reducing Na+ uptake) and prolonging repolarization of phase 3 (slowing down K+ release). (wikipedia.org)
  • citation needed] Izatt and his colleagues were the first to attach macrocycles to a solid matrix and make highly selective metal separations. (wikipedia.org)
  • analyte
  • When an analyte is in its neutral form, it becomes more hydrophobic and retention strengthens under reversed-phase conditions. (sigmaaldrich.com)
  • Ion exchange sorbents separate analytes based on electrostatic interactions between the analyte of interest and the positively or negatively charged groups on the stationary phase. (wikipedia.org)
  • Once the charge is neutralized, the electrostatic interaction between the analyte and the stationary phase no longer exists and the analyte will elute from the cartridge. (wikipedia.org)
  • Ion suppression in LC-MS and LC-MS/MS refers to reduced detector response, or signal:noise as a manifested effect of competition for ionisation efficiency in the ionisation source, between the analyte(s) of interest and other endogenous or exogenous (e.g. plasticisers extracted from plastic tubes, mobile phase additives) species which have not been removed from the sample matrix during sample preparation. (wikipedia.org)
  • It has been widely observed that for many analytes, at high concentrations, ESI exhibits a loss of detector response linearity, perhaps due to reduced charge excess caused by analyte saturation at the droplet surface, inhibiting subsequent ejection of gas phase ions from further inside the droplet. (wikipedia.org)
  • The third proposed theory for ion suppression in ESI relates to the presence of non-volatile species which can either cause co-precipitation of analyte in the droplet (thus preventing ionisation) or prevent the contraction of droplet size to the critical radius required for the ion evaporation and/or charge residue mechanisms to form gas phase ions efficiently. (wikipedia.org)
  • samples
  • The thesis focuses on the development of miniaturised solid phase extraction (SPE) technologies for the rapid and effective processing of complex biological samples prior to mass spectrometry (MS) analysis. (edu.au)
  • The method validation results showed that the limit of detection ranged from 0.021-3.854 μg kg−1and 0.015-1.198 ng mL−1 for solid and liquid samples, respectively. (wikipedia.org)
  • Chemistry
  • In other words, it may be difficult for a reversed-phase method or bonded chemistry to differentiate between molecules that are structurally similar. (sigmaaldrich.com)
  • Through the use of high affinity of fluorous tags (ponytails) for fluorous phases or fluorous-derivatized solid phases allows for near complete recovery of the tagged reagent (i.e., near complete reduction in a chemical waste stream), making the use of fluorous chemistry techniques a popular topic in green chemistry. (wikipedia.org)
  • retain
  • However, because reversed-phase will retain most molecules with any hydrophobic character, it is very useful for extracting analytes that are very diverse in structure within the same sample. (sigmaaldrich.com)
  • recovery
  • The polymer monolith adsorbents demonstrated a clear advantage for the small probes, as a high extraction performance (high recovery) could be achieved independent of flow rate. (edu.au)
  • high
  • DNA extraction on microchips provides a fast, cost effective, and effective for high-throughput screening, which also has a very small footprint. (wikipedia.org)
  • studies
  • In the studies of supercritical extraction, however, "supercritical fluid" is applied for a narrow temperature region of 1-1.2 T c {\displaystyle T_{c}} or T c {\displaystyle T_{c}} to T c {\displaystyle T_{c}} +10 K, which is called the supercritical region. (wikipedia.org)