Solid organ injuries. Medical search. Frequent questions

Although kidney transplantation is the most effective treatment for children with kidney failure, rejection of the transplanted organ by the recipient's immune system is a major concern. (medicalxpress.com)
This technology has the potential to extend the window of time between procurement and transplantation in the growing field of Reconstructive Transplantation as well as solid organ transplants. (sages.org)
Liver Transplantation Liver transplantation is the 2nd most common type of solid organ transplantation. (merckmanuals.com)
First, there is great clinical need to develop alternative therapies for end stage liver disease, which is currently treated by liver transplantation and severely limited by the shortage of donor organs. (ucsf.edu)
Patients on immunosuppressants (eg, immunosuppression after solid organ transplantation) have increased numbers of more persistent and more chronic keratoacanthomas. (logicalimages.com)
AKD may be superior to AKI in predicting risk of CKD in children after non- kidney solid organ transplantation . (bvsalud.org)
For these infections, the initial link to the transplanted organ was made by histopathologic evaluation and immunohistochemical testing of tissue from an organ recipient who died 4 weeks after undergoing transplantation. (cdc.gov)
The transmission of rabies virus through cornea transplantation has been described, but transmission through solid organ transplantation was not recognized before 2004. (cdc.gov)
Over the last decade, improvements in surgical techniques, lung preservation, immunosuppression, and management of ischaemia/reperfusion injury and infections have made intermediate-term survival after lung transplantation an achievable goal. (ersjournals.com)
Over the last decade, improvements in surgical techniques, lung preservation, immunosuppression, and management of ischaemia/reperfusion injury and infections have contributed to increase the 1‐yr patient survival after lung transplantation (LTx) to 70-80% 1 . (ersjournals.com)
A shift in the nature of complications from early to late graft dysfunction has been similarly observed after transplantation of other solid organs 2 . (ersjournals.com)
All transplanted participants (any solid organ, or bone marrow transplantation). (who.int)

This pathway is intended to treat children who present to the Emergency Department with suspected solid organ injuries to the liver, spleen, or kidney. (chop.edu)
It is important that radiologists be familiar with the liver, spleen and kidney injury grading system based on CT features that was established by the American Association for the Surgery of Trauma (AAST). (icrjournal.ir)
He discusses pediatric blunt liver/spleen injuries and the guidelines for the management of these injuries. (arizonatrauma.org)
Causes of hemoperitoneum include:[citation needed] Penetrating trauma Blunt trauma, most commonly injuries to solid organs such as the liver and spleen. (wikipedia.org)
citation needed] With modern diagnostic aids such as computed tomography (CT) scans, certain injuries such as low-grade lacerations of the spleen may be diagnosed early and observed, with surgical options deferred unless clinical deterioration obligates them. (wikipedia.org)
2018). Organ injury scaling 2018 update: spleen, liver, and kidney. (winamp.com)
1 Liver injury can be present in up to 10% of blunt abdominal traumas, but occurs in isolation much less commonly than the spleen. (mhmedical.com)
Sudden deceleration injury or transmission of blunt force directly to the spleen or liver is responsible for most cases of intraperitoneal hemorrhage after trauma. (mhmedical.com)
Solid organs like the spleen, liver, and kidneys can tear slightly. (mountdenniswestonphysiotherapy.com)
The organs that are usually affected are the: liver, large and small intestine, and spleen. (expressercare.com)

The role of interventional radiologists in trauma cases has evolved from that of making the initial diagnosis of vascular and solid organ injuries to that of temporizing or definitive treatment. (medscape.com)
Splenic artery embolization should be considered in hemodynamically stable patients with grade IV/V blunt splenic trauma or with any grade injury who have imaging or clinical evidence of splenic hemorrhage. (medscape.com)
Images of vascular and solid organ trauma are shown below. (medscape.com)
Vascular and solid organ trauma. (medscape.com)
The addition of PO contrast does not improve detection of intra-abdominal injury and should be avoided unless directed by the Trauma Surgical team. (chop.edu)
In the past, patients with blunt trauma underwent laparotomy for detection and potential treatment of traumatic injuries. (icrjournal.ir)
CT scan is the diagnostic modality of choice for the evaluation of blunt solid organ trauma in hemodynamically stable patients. (icrjournal.ir)
Imaging in Abdominal Trauma: Solid Organ Injuries', Iranian Congress of Radiology , 38(2), pp. 56-56. (icrjournal.ir)
Dr. Christian Streck presented New APSA Guidelines for Pediatric Solid Organ Injury at the 11th annual Southwest Trauma & Acute Care Symposium on Thursday, November 14, 2019. (arizonatrauma.org)
9 ] Another study found that patients over 50 with motorcycle-related injury trauma required more aggressive treatment and longer hospital stays, but did not have more severe injuries than patients under 50. (bcmj.org)
This is dangerous in trauma patients because it may exacerbate a cervical spine injury. (medscape.com)
Abdominal injuries may occur in up to one-third of all patients who suffer severe trauma, but little is known about epidemiological trends and characteristics in a Northern European setting. (uib.no)
This study investigated injury demographics, and epidemiological trends in trauma patients admitted with abdominal injuries. (uib.no)
Among 7202 admitted trauma patients, 449 (6.2%) suffered abdominal injuries. (uib.no)
The incidence of splenic injury in blunt abdominal trauma has been reported as high as 25% in literature. (sages.org)
Close observation has become an accepted treatment of stable splenic injuries from blunt trauma. (sages.org)
Blunt force trauma is the medical term for a blunt object hitting the body with minimal or no penetration of the skin (in contrast to penetrating injuries discussed below). (parathyroid.com)
Blunt force trauma can cause injury to many parts of the body, and most frequently this results in broken bones and various soft tissue injuries and not death. (parathyroid.com)
Renal trauma is classified according to the American Association for the Surgery of Trauma (AAST) Renal Injury Grading Scale into grades I-V [4] ( Table 1 ). (ugeskriftet.dk)
The impact of obesity on severity of solid organ injury in the adult population at a Level I trauma center. (ucsf.edu)
Trauma surgeons practice what they preach: The NTDB story on solid organ injury management. (proquest.com)
Topic: Imaging of Acute Trauma, Solid Organ Injury Summary: In this episode, we continue a discussion of imaging acute trauma. (winamp.com)
Skin injury may also be a predisposing factor, as there are many reports of keratoacanthomas developing in sites of previous trauma, in surgical scars, after laser resurfacing, and following radiation therapy. (logicalimages.com)
All trauma professionals are aware of the evils of anticoagulation in patients who sustain traumatic brain injury. (thetraumapro.com)
Splenic injury constitutes up to 49% of visceral injury after blunt trauma. (mhmedical.com)
Diaphyseal femur fractures, which commonly result from a high-energy mechanism of injury, may be isolated or associated with multisystem trauma. (medscape.com)

High grade splenic injury (grade III and higher AAST) tend to have a higher transfusion requirement and increased morbidity and mortality. (sages.org)
A 12-year-old girl suffered from grade III and IV splenic injury (AAST) after a fall from a bicycle. (sages.org)
The AAST classification of the renal injury is a predictor of morbidity and intervention [5]. (ugeskriftet.dk)
Injuries to the kidney were graded using the AAST kidney injury scale, and the data are presented in Figure 1 by length of hospital stay. (ugeskriftet.dk)
AAST Injury Scoring Scale. (winamp.com)

The report added that Su did not have any obvious injuries, but her internal organs were affected. (ibtimes.com)
Complications from acupuncture are rare but can include infection and injury to internal organs or the spinal cord due to poor technique. (marcwallace.com)

Since 2002, several types of emerging donor-derived infections have been reported with increasing frequency among solid organ transplant recipients seeking medical care for encephalitis. (cdc.gov)

Nonoperative management is becoming the treatment of choice for patients with blunt hepatic injury who are hemodynamically stable, resulting in decreased abdominal infections, transfusions, and length of hospital stay. (medscape.com)
Emergency laparoscopy was demonstrated to be and effective diagnostic and therapeutic modality in the management of blunt abdominal injuries in hemodynamically stable child. (sages.org)

Maintenance of immunosuppression after solid-organ transplant is essential in order to prevent short-and long-term complications such as acute cellular rejection and chronic lung allograft dysfunction. (nih.gov)

This was an observational cohort study of all consecutive patients admitted to Stavanger University Hospital (SUH) with a documented abdominal injury between January 2004 and December 2018. (uib.no)
Tuberculosis transmission across three states: the story of a solid organ donor born in an endemic country, 2018. (cdc.gov)
In 2018, four solid organ transplant recipients residing in three states but sharing a common organ donor were diagnosed with TB disease. (cdc.gov)

The blood accumulates in the space between the inner lining of the abdominal wall and the internal abdominal organs. (wikipedia.org)
DPL is invasive and risks iatrogenic damage to abdominal organs during the procedure. (msdmanuals.com)

The risk for infections caused by pathogens transmitted through solid organ or tissue transplants, referred to here as donor-derived or transplant-transmitted infections, has been recognized for decades and remains a worldwide public health problem. (cdc.gov)
It is likely that signs and symptoms of encephalitis among transplant recipients during a West Nile virus outbreak led to the recognition that West Nile virus had been transmitted through organ transplants. (cdc.gov)

Specifically, she is interested in the GLP- 1 receptor and its role in hepatic steatosis, apoptosis and autophagy in the setting of ischemia reperfusion injury. (choa.org)
To mitigate obligate reperfusion injury in VCA, we evaluate the efficacy of a novel normothermic hyperbaric oxygen warm ex-vivo perfusion strategy using hyperoxygenated University of Wisconsin (UW) solution in a porcine VCA model. (sages.org)

Patients with severe (grade III or higher) splenic injuries have higher failure rates, along with transfusion requirement and increased morbididy and mortality. (sages.org)
Contrast extravasation on CT evaluation is associated with negative outcomes in children with blunt splenic injuries, determining a failure of NOM and the need for surgical intervention. (sages.org)
Splenic injury presents with abdominal pain, with referred pain to the left shoulder (Kehr sign), while the pain after a liver injury can radiate to the right shoulder. (mhmedical.com)

Penetrating injuries, unstable patients and grade V injuries often require surgical intervention. (ugeskriftet.dk)
Over 80 percent of penetrating wounds leading to abscesses occurred in the upper quadrants, and common risk factors included multiple intraabdominal solid organ injuries requiring open drainage, coupled with gastrointestinal tract perforation. (nih.gov)

All solid organs and most other tissues harbor a network of DC or macrophages (Table 1 ). (hindawi.com)
For medical graduates, a comprehensive knowledge of anatomy is crucial to comprehend the structural bond between organs, tissues, and other components. (1888pressrelease.com)
Surgery involves precise manipulation of organs and tissues, and any error could have severe consequences for the patient. (1888pressrelease.com)

HEV infection is usually an acute self-limiting disease, but causes chronic infection with rapidly progressive cirrhosis in adult and pediatric organ-transplant-patients. (unboundmedicine.com)
Acute kidney disease predicts chronic kidney disease in pediatric non-kidney solid organ transplant patients. (bvsalud.org)

The goal of this research is to better inform pre- and post-transplant clinical management and further refine donor-recipient organ matching to improve long-term outcomes and survival in lung transplant patients. (nih.gov)
Laboratory and epidemiologic data substantiated this mode of virus transmission and documented that the organ donor had likely acquired West Nile virus through a blood transfusion. (cdc.gov)
however, this may not be the case in the solid organ-transplant setting because organ donor screening has not been mandated. (cdc.gov)
In July 2004, CDC was notified that 3 recipients of solid organs and 1 recipient of an iliac artery segment from a common donor had died from encephalitis, which was eventually found to be caused by rabies virus infection. (cdc.gov)
Transmission of tuberculosis (TB) from a deceased solid organ donor to recipients can result in severe morbidity and mortality. (cdc.gov)
The organ donor was born in a country with a high incidence of TB and experienced 8 weeks of headache and fever prior to death, but was not tested for TB during multiple hospitalizations or prior to organ procurement. (cdc.gov)
TB isolates of two organ recipients and a close contact of the donor had identical TB genotypes and closely related whole-genome sequencing results. (cdc.gov)

Emergent thoracic endovascular aortic repair (TEVAR) should be used in anatomically favorable grade 3 and grade 4 aortic injuries, with nonoperative management (antihypertensive and antiimpulse medication with close symptomatic and/or radiographic follow-up) favored for grade 1 and grade 2 injuries. (medscape.com)

Angiography and embolization should be considered in patients with grade III/IV renal injuries when surgical exploration is not warranted. (medscape.com)
HEV infection evolves to chronic hepatitis in nearly 60% of HEV-infection solid-organ-transplant patients. (unboundmedicine.com)
Its use is restricted to those patients in whom cervical spine injury has been excluded. (medscape.com)
Multiple abdominal injuries were recorded in 44% (197/449) and polytrauma in 51% (231/449) of the patients. (uib.no)
In medical practice, physicians encounter patients with various medical conditions and injuries. (1888pressrelease.com)
Then break it down (A) Epithelial tumors (cystic with solid components) - Benign - Borderline - Malignant (B) Sex cord stromal tumors (solid with cystic components) - Fibroma - Other stuff (C) Germ cells tumors (bizarre masses in young patients) - Dermoid cyst - Other stuff Hosts: Christopher Cerniglia, DO, ME, FAOCR. (winamp.com)
Reference: Outcomes in traumatic brain injury for patients presenting on antiplatelet therapy. (thetraumapro.com)
Improvements in immune-modulating therapy, critical care medicine, and surgical techniques have led to the increased success of organ transplantations, and more patients are now eligible for these procedures. (cdc.gov)

The most frequent organ injury was liver injury, found in 38% (169/449). (uib.no)

Current treatment options for blunt solid organ injuries include non- operative management, angioembolization, and surgery. (icrjournal.ir)
In order to translate regenerative surgery from concept to therapeutic reality, our lab focuses on a complex and vital solid organ, the liver, for several reasons. (ucsf.edu)
A blunt injury to the abdomen is usually managed conservatively, but the use of interventional radiology and maybe surgery will be indicated with the severe injuries. (expressercare.com)
The patient underwent surgery under general anesthesia to remove the impacted tooth and radiopaque injury. (bvsalud.org)

Transplant rejection is detected by analyzing a biopsy of the transplanted organ. (nih.gov)
Could early detection and treatment of rejection save the transplanted organ from rejection? (nih.gov)

acute kidney injury (AKI) event. (bvsalud.org)
Current (within 4 weeks prior to study treatment administration in the REP) acute kidney injury (AKI) defined by AKIN criteria. (who.int)

Another small incision sometimes is needed during organ or tissue resections. (stlouischildrens.org)
We further discuss how injuries alter tissue environments and how this primes mononuclear phagocytes to enforce this particular environment, for example, to support host defense and pathogen clearance, to support the resolution of inflammation, to support epithelial and mesenchymal healing, and to support the resolution of fibrosis to the smallest possible scar. (hindawi.com)
Mononuclear phagocytes contributions to tissue pathologies relate to their central roles in orchestrating all stages of host defense and wound healing, which often become maladaptive processes, especially in sterile and/or diffuse tissue injuries. (hindawi.com)
During the last decades, research has focused on the cell-type-specific properties of these cells in culture, which then led to an immunocentric view of their role in disease like if they were primed like T cells to infiltrate target organs to cause tissue damage and drive progressive scaring [ 2 , 3 ]. (hindawi.com)
In this paper we apply the tissue-centric perspective to discuss the role of resident and infiltrating macrophages and dendritic cells in different organs. (hindawi.com)
We examine tissue needs to maintain homeostasis and how to regain homeostasis upon tissue injury. (hindawi.com)
In the near future, our armamentarium will increase to include using our surgical skills to induce tissue regeneration in situ or to implant ex vivo engineered organs. (ucsf.edu)
Finally, building a solid organ such as the liver ex vivo remains the most challenging goal in tissue engineering and a problem of sufficient difficulty that is worthy of intense focus. (ucsf.edu)
Direct contact with the solid or with concentrated solutions causes thermal and chemical burns leading to deep-tissue injuries. (cdc.gov)

HEV can also cause extra-hepatic manifestations, such as neurological symptoms and kidney injury. (unboundmedicine.com)

She is currently in stable condition, but is yet to speak or eat solid food. (ibtimes.com)
The overall adjusted incidence rate of abdominal injuries remained stable. (uib.no)
Grade I-III injuries are managed conservatively, and more evidence now supports also managing grade IV injuries conservatively if they are haemodynamically stable [2, 4]. (ugeskriftet.dk)
If a stable haematoma is detected in a patient with other injuries, the haematoma should not be opened [2]. (ugeskriftet.dk)

Surgical Management of Solid Organ Injuries. (uab.edu)
Surgical repair of vascular injuries is rarely successful and nephrectomy is a safer choice [6]. (ugeskriftet.dk)
Second, the liver has enormous innate capacity to regenerate in response to injury and metabolic demand, a feature that can be exploited to facilitate development of regenerative surgical approaches. (ucsf.edu)

In an analysis using National Electronic Injury Surveillance System data for motorcycle crash injuries treated in emergency departments from 2001 to 2008, adults age 60 and older were found to have the greatest rate of increase in injuries, were more likely to be hospitalized, and suffered more severe injuries than younger riders. (bcmj.org)
It is natural to be worried about a possible concussion, shoulder dislocation, skier's thumb, spine injuries, fractures, and other severe injuries resulting from a single slip-on snowy terrain. (cordilleralodge.com)

The most vulnerable organ is your skull, as a single strike increases the likelihood of brain damage. (cordilleralodge.com)

Rarely, DPL is indicated when imaging is available, such as in hypotension plus an unclear E-FAST examination result or imaging that shows free pelvic fluid but no apparent solid organ injury (eg, ascites). (msdmanuals.com)
Watch the pelvic and abdominal injuries as they can cause life-threatening hemorrhage. (expressercare.com)

Associated lesions are common and include ipsilateral rib fractures, hemothorax or pneumothorax, lung lacerations, and renal or adrenal injuries. (mhmedical.com)

Histological evaluation revealed extensive diffuse evidence of necrosis in all controls (at 3 hours, cold static preservation) but flaps placed on hyperbaric ex-vivo perfusion support showed decreased histologic evidence of ischemic injury or necrosis ranging from rare to moderate. (sages.org)

Retroperitoneal hemorrhage can also be associated with major vascular injuries or malignancy and can be spontaneous. (mhmedical.com)

Sean died of a sudden deceleration injury just like Allen, Cause of Death number 4 below. (parathyroid.com)

Conditions such as large abdominal tumors and traumatic solid organ injuries are not treated endoscopically. (stlouischildrens.org)

In Section 4 (Sudden Deceleration Injuries) we will look at the death of Allen and Sean more closely and conclude that these were foreseeable and predictable crashes that resulted in deaths that were preventable and avoidable. (parathyroid.com)
Some of the forms of the standard mechanisms for blunt injury are falls, assaults, sports injuries, and automobile crashes. (expressercare.com)

However, DPL is more sensitive than E-FAST for mesenteric, diaphragmatic, and hollow viscus injury because these injuries (and the lesser volume of hemorrhage they produce) are more difficult to visualize on imaging. (msdmanuals.com)

Traumatic injuries of the pancreas are uncommon and often difficult to diagnose owing to subtle imaging findings, confounding multi-organ injuries, and nonspecific clinical signs. (icrjournal.ir)
Findings from research in the United States show an increase in injury and mortality rates among older male motorcycle riders. (bcmj.org)
Findings indicated longer hospital stays and different injury patterns for older male riders compared with younger male riders, and higher hospitalization rates for older male riders in less urban parts of BC. (bcmj.org)
Our findings suggest the need for an evidence-based injury prevention initiative targeting older male motorcycle riders. (bcmj.org)

It may be that transmission is possible because of viral persistence in donated organs after peripheral viremia has cleared or because of intermittent viremia from a reservoir organ, such as a kidney. (cdc.gov)

Injuries in this region seem to increase the chances of the mediastinal, chest, and diaphragmatic injuries. (expressercare.com)

Transport-related accidents were the most frequent cause of injury in 57% (257/449). (uib.no)
Based on the current data, prevention efforts focusing on the most frequent injury events and diagnoses may be warranted. (cdc.gov)

This is a retrospective cohort study of all children undergoing non- kidney solid organ transplant between 2011 and 2019 at UPMC Children 's Hospital of Pittsburgh. (bvsalud.org)

Learning to identify hidden collision injuries ensures you get proper medical care and avoid chronic problems. (mountdenniswestonphysiotherapy.com)

Injuries secondary to ischemia and cold preservation are mitigated. (sages.org)

Because trends in ridership and injuries have not been well investigated in Canada, we undertook a study to determine the effect of the increasing age of male motorcycle riders on injury patterns in British Columbia. (bcmj.org)
To examine the relationship between rider age and injury patterns, we analyzed data from British Columbia's motorcycle-related Discharge Abstract Database for 2001 to 2010. (bcmj.org)
Trends in motorcycle ridership and injury patterns have not been well investigated in Canada, despite potential safety concerns and implications for the health care system. (bcmj.org)
Our objective was to analyze hospitalization data to examine the influence of the increasing age of male motorcyclists on injury patterns and outcomes in British Columbia. (bcmj.org)
Injury demographics, age- and sex-adjusted incidence, and mortality patterns are analyzed across three time periods. (uib.no)

Transportation industry statistics from the United States and reports from US researchers indicate an increase in injury and mortality rates for older male motorcyclists. (bcmj.org)

Digital subtraction catheter aortogram (early phase) of a typical acute traumatic aortic injury. (medscape.com)
Digital subtraction catheter aortogram (late phase) of a typical acute traumatic aortic injury (same patient as in the previous image). (medscape.com)

Cysts are pathological cavities, enclosed by the epithelium, which may contain liquid, solid or semi-solid material. (bvsalud.org)

For example, organs like the lung and the liver are exposed to pathogen components from the air or from the gut barrier, respectively, which explains the predominance of a macrophage phenotype that has a higher capacity for phagocytic clearance of pathogen components. (hindawi.com)

Management of infectious diseases is a critical component of care of solid organ transplant recipients. (biomedcentral.com)

The median Injury Severity Score (ISS) was 21, and the median New Injury Severity Score (NISS) was 25. (uib.no)

If the wound was made by a projectile, then that injury in the abdomen could be caused by an entry wound in about any part of your body. (expressercare.com)

Anatomy11

Organisms4

Diseases42

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment18

Phenomena and Processes6

Information Science2

Named Groups1

Health Care6

Transplantation12

Spleen10

Trauma26

AAST5

Internal organs2

Among solid organ transplant recipients1

Hemodynamically stable2

Immunosuppression1

20183

Abdominal organs2

Transplants2

Reperfusion injury2

Splenic3

Penetrating2

Tissues3

Pediatric2

Donor7

Nonoperative management1

Patients8

LIVER-INJURY1

Surgery4

Rejection2

Acute kidney2

Tissue9

Kidney injury1

Stable4

Surgical3

Severe injuries2

Damage1

Pelvic2

Renal1

Ischemic injury1

Vascular injuries1

Deceleration injury1

Tumors1

Crashes2

Hemorrhage1

Findings4

Peripheral1

Diaphragmatic1

Frequent2

Cohort1

Chronic1

Ischemia1

Patterns5

Mortality1

Catheter2

Cysts1

Lung1

Management1

Severity1

Abdomen1