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  • histology
  • Primary Site/Corpus uteri: Is the primary site C541 (endometrium) or C543 (uterine fundus) when the histology states endometrial adenocarcinoma, endometrioid type, but tumor site states fundus? (cancer.gov)
  • tumour cells
  • one of our cases demonstrates a transition from a solid hidradenoma-like pattern to nests of tumour cells floating in mucin lakes, adding support for the sweat gland hypothesis. (curehunter.com)
  • cystic
  • The 1999 World Health Organization classification system defined MCACL as a cystic adenocarcinoma with copious mucin production that, histologically, resembles (the more common) mucus-producing cystadenocarcinomas originating in the ovary, breast and pancreas. (wikipedia.org)
  • and poroid hidradenoma, which is a solid-cystic, dermal poroma. (curehunter.com)
  • Ultrasonography of right iliac fossa showed a well-defined hypoechoic cystic tubular lesion measuring 10 x 5 centimetres, with hyperechoic internal debris and no evidence of septations, solid components or surrounding inflammatory changes (Figure 1). (eurorad.org)
  • malignant
  • 4 Unitat de Biologia Cellular i Molecular, Institut Municipal d Investigacio Medica, Barcelona, Spain and 5 Department of Biochemistry and Molecular Biology, UNMC/Eppley Cancer Center, University of Nebraska Medical Center, NE, USA The distinction between pleural malignant mesothelioma and pleural infiltration by adenocarcinomas has complex therapeutic and medicolegal implications. (docplayer.net)
  • MUC4 is a membrane-bound mucin that has been suggested to be implicated in malignant progression in humans and rats. (docplayer.net)
  • We conclude that MUC4 is a very specific (100%) and sensitive (91.4%) marker of lung adenocarcinomas on paraffin-embedded tissue that could be useful in diagnostic practice in the distinction between malignant mesothelioma and adenocarcinoma. (docplayer.net)
  • differential diagnosis Immunohistochemistry provides an important tool for distinguishing pleural malignant mesothelioma from peripheral lung adenocarcinoma invading the pleura or from a metastatic adenocarcinoma arising in a distant organ. (docplayer.net)
  • 3,16 MOC-31 immunostaining is also a useful marker of lung adenocarcinomas although positive immunostaining in a limited number of cells has been described in malignant mesotheliomas. (docplayer.net)
  • stain
  • Most of these markers, such as BerEP4, CD15, the thyroid transcription factor (TTF-1) and carcinoembryonic antigen (CEA) stain adenocarcinomas whereas calretinin and CK5/6 are positive in both benign Correspondence: Professor M-C Copin, Service d Anatomie et Cytologie Pathologiques, Hôpital Calmette, CHRU, Bd J. Leclercq, Lille Cedex, France. (docplayer.net)
  • microscopic
  • Electron microscopic studies in 3 cases described intracytoplasmic mucin, convoluted oval nuclei, prominent nucleoli, homogeneous euchromatin with peripheral chromatin condensation, microvilli, junctional complexes, and primitive lumen formation. (wikipedia.org)
  • tissue
  • MUC4 protein was expressed in 32 of 35 (91.4%) lung adenocarcinomas on paraffin-embedded tissue. (docplayer.net)
  • Even the classic syndrome probably represents a spectrum of disorders, ranging from exaggerated fluid-phased thrombosis dependent on prothrombotic agents such as tissue factor to a platelet- and endotheliumum-based selectin-dependent microangiopathy associated with mucin-producing carcinomas, along with thrombin and fibrin production. (bloodjournal.org)
  • malignancies
  • We discuss counter strategies that may be adopted to augment the efficacy of NK cell anti-tumor surveillance, the clinical trials that have been undertaken so far in solid malignancies, critically weighing the challenges and opportunities with this approach. (frontiersin.org)
  • We discuss the strategies that may be employed to derive effective medicine, the promise and challenges of these approaches for solid malignancies. (frontiersin.org)
  • form
  • however, among people who have smoked fewer than 100 cigarettes in their lifetimes ("never-smokers"), adenocarcinoma is the most common form of lung cancer. (wikipedia.org)
  • risk
  • This and other studies reported increasing numbers of total pancreatectomies being performed for hereditary pancreatitis and IPMNs, both strong risk factors for pancreatic ductal adenocarcinoma [1, (cancerlink.ru)
  • According to the Nurses' Health Study, the risk of adenocarcinoma of the lung increases substantially after a long duration of previous tobacco smoking, with a previous smoking duration of 30 to 40 years giving a relative risk of approximately 2.4 compared to never-smokers, and a duration of more than 40 years giving a relative risk of approximately 5. (wikipedia.org)