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Hyaluronic AcidViscosupplementsOphthalmic SolutionsInjectionsDry Eye SyndromesInjections, Intra-ArticularMethylcelluloseRose BengalPurinergic P2Y Receptor AgonistsSodiumLenses, IntraocularCarboxymethylcellulose SodiumTearsRetinal DetachmentPolyphosphatesMorphinansChondroitin SulfatesViscosityHyaluronoglucosaminidaseAnterior ChamberFluoresceinUracil NucleotidesSuperficial Back MusclesCorneaCorneal TransplantationObserver VariationInjections, IntravenousRabbitsInjections, IntramuscularCataract ExtractionTreatment OutcomeOsteoarthritisReproducibility of ResultsSodium ChannelsInjections, IntralesionalInjections, SubcutaneousAdjuvants, ImmunologicDouble-Blind MethodComb and WattlesDisease Models, AnimalRandom AllocationPolysaccharide-LyasesLaryngeal CartilagesTime FactorsGlycosaminoglycansInjections, IntraperitonealWound HealingGlycosyltransferasesAntigens, CD44ChondroitinInjections, IntraventricularInjections, IntradermalTransferasesInjections, EpiduralPostoperative ComplicationsSodium, DietaryUridine Diphosphate N-AcetylglucosamineUridine Diphosphate Glucuronic AcidSodium ChlorideInjections, Intra-ArterialIntravitreal InjectionsInjections, SpinalProteoglycansInjections, JetInjections, IntraocularGlucuronosyltransferaseChondrosarcomaRats, Sprague-DawleyTissue AdhesionsIntraoperative ComplicationsSensitivity and SpecificityKineticsDose-Response Relationship, DrugPregnancyTomography, X-Ray ComputedUridine Diphosphate N-AcetylgalactosamineMicroinjectionsFlow Injection AnalysisSodium Channel BlockersMolecular WeightRats, WistarXenopus ProteinsGlucosamineSodium IsotopesCells, CulturedSodium BicarbonateProspective StudiesCartilagePeriodic AcidRetrospective StudiesSodium Dodecyl SulfateReceptors, Lymphocyte HomingSubstance Abuse, IntravenousSperm Injections, IntracytoplasmicBrazilCattleMagnetic Resonance ImagingChromatography, GelMice, Inbred C57BLSyringes
CartilageHyaluronicHyaluronanNSAIDsEffusionCorticosteroidExtra-articularViscosupplementationSyringeOsteoarthritis of the kneeMolecularSystemicPrecautionsEfficacyRadiographyDiclofenac sodiumHypersensitivitySalineSynviscGram-positive bacterial proteinsTissuesClinicalMediatorsQuaternary ammonPatientsWidelySevereRednessJointNeedleInflammationTreatmentConcentrationTherapeuticMonthsSolutionProcedureApplicationSkinCurrent
Cartilage19
  • Lameness is most commonly associated with injury to synovial joints, or those joints containing articular cartilage, a joint capsule, and a synovial membrane. (wikipedia.org)
  • Joint disease may affect the joint capsule and synovial membrane, articular cartilage, subchondral bone (the bone underneath the cartilage), menisci, or any ligaments associated with the joint. (wikipedia.org)
  • While degeneration of articular cartilage is a common disease process in working animals, resulting in osteoarthritis, cartilage is aneural (does not contain nerves) and does not produce pain. (wikipedia.org)
  • Pain associated with osteoarthritis is secondary to joint capsule pain, due to joint distention and reduced range of motion, or to pain from the underlying bone, which may become damaged following erosion of the articular cartilage. (wikipedia.org)
  • Inflammatory products, such as inflammatory mediators and cytokines, damage articular cartilage and have been shown to weaken intra-articular ligaments. (wikipedia.org)
  • Debris within the joint, such as from a chip fracture, can cause long term damage to the synovium and articular cartilage leading to osteoarthritis, and is therefore best removed. (wikipedia.org)
  • The body will try to repair full-thickness cartilage defects using scar tissue or fibrocartilage, both of which are poor substitutes for normal, healthy articular cartilage. (wikipedia.org)
  • Mesenchymal stem cells (MSCs) play a key role in articular cartilage repair. (hindawi.com)
  • Native and concentrated BMA have been intensively studied in the context of articular cartilage repair. (hindawi.com)
  • Such enhanced techniques of marrow stimulation have been shown to improve articular cartilage repair in both animal models and patients. (hindawi.com)
  • This substance is a component of hyaluronic acid, which is present in high concentrations in synovial fluid and articular cartilage. (beautydermal.com)
  • Articular cartilage Biochemistry. (biomedcentral.com)
  • Unlike the larger, more proximal joints of the lower extremity, primary idiopathic osteoarthritis is not the leading cause of damage to ankle joint articular cartilage. (faoj.org)
  • Why Is HA Important to Articular Cartilage and Joint Fluid? (eacanimalcare.com)
  • Articular cartilage and joint fluid contain hyaluronic acid, and HA contributes to their performance. (eacanimalcare.com)
  • [ 1 ] It can be thought of as a degenerative disorder arising from the biochemical breakdown of articular (hyaline) cartilage in the synovial joints. (medscape.com)
  • However, the current view holds that osteoarthritis involves not only the articular cartilage but the entire joint organ, including the subchondral bone and synovium. (medscape.com)
  • the researchers concluded, "The findings of the current study suggest that positive effects of intra-articular injections of PRP might improve quality of life and reduce the pain of patients suffering from osteoarthritis of the knee joint independent from the level of cartilage damage. (aestheticsadvisor.com)
  • Medical Sodium Hyaluronate Gel Being widely used for viscoelastic solution for ophthalmic surgery, joint protection of articular cartilage, and anti-adhesion in abdominal and pelvic surgery, this line of products are animal-origin free medical polymer materials extracted and refined by high-tech bio-engineering from streptococcal fermentation metabolites with high viscoelasticity, lubricity, physical alterability, and good biocompatibility. (singcleanmedical.com)
Hyaluronic13
Hyaluronan9
  • 1 syringe Gow-it contains: 1% solution of sodium hyaluronan 2.5 ml (25 mg), obtained from a culture of Streptococcus Equi by fermentation and subsequent purification. (bestpharmbuy.com)
  • Performing the function of tissue lubrication, sodium hyaluronan plays an important role in regulating the physical and mechanical interaction between the surrounding tissues, in addition, it acts as a viscoelastic element that prevents adhesion of tissues. (bestpharmbuy.com)
  • Different forms of sodium hyaluronan have a different molecular weight, but the same chemical structure. (bestpharmbuy.com)
  • The drug GO-ON is a 1% solution of sodium hyaluronan, which is obtained from a culture of Streptococcus Equi by fermentation and subsequent purification. (bestpharmbuy.com)
  • It was found that as a result of intra-articular injection of sodium hyaluronan solutions, the visco-elastic properties of synovial fluid are improved. (bestpharmbuy.com)
  • It was found that sodium hyaluronan in animals is excreted in milk, therefore during the period of treatment it is not recommended to breastfeed. (bestpharmbuy.com)
  • The biological turnover of hyaluronan (sodium hyaluronate) of different molecular weights (0.6×10 6 and 2.5×10 6 Daltons) was studied in the synovial fluid of the middle carpal and metacarpophalangeal joints of 6 clinically healthy Standardbred horses. (biomedcentral.com)
  • The hyaluronan was radioactively labelled with 14 C. The biological half-life (t 1/2 ) was calculated from repeated synovial samples after injection of the labelled hyaluronan. (biomedcentral.com)
  • Hylan A and B are derived from hyaluronan, also known as sodium hyaluronate. (polarbearmeds.com)
NSAIDs1
  • Pharmacologic agents, such as non-steroidal anti-inflammatory drugs (NSAIDs), intra-articular steroidal injections, and visco-supplementation with sodium hyaluronate injection may be beneficial in reducing symptoms [3]. (faoj.org)
Effusion4
  • When an articular effusion is formed, it is recommended to puncture, immobilize the joint, put an ice pack and / or insert corticosteroids inside the joint. (bestpharmbuy.com)
  • Articular effusion. (bestpharmbuy.com)
  • Sodium hyaluronate should not be administered if there is a significant intra-articular effusion. (bestpharmbuy.com)
  • Prior to each Synvisc injection, remove synovial fluid or effusion using an 18- to 22-gauge needle. (polarbearmeds.com)
Corticosteroid3
Extra-articular2
  • Many authors have shown that the pathology of FS is in the extra-articular structures, such as the coracohumeral ligament, the interval of the rotator cuff, the subacromial space, and the articular capsule. (medscape.com)
  • It is impossible to enter extra-articular, including, into the synovial tissue or joint capsule. (bestpharmbuy.com)
Viscosupplementation2
  • We evaluated the efficacy of intra-articular viscosupplementation with sodium hyaluronate in the management of osteoarthritis of the subtalar joint. (unisa.it)
  • Synvisc one injection, also known as Hylan GF20, is an effective viscosupplementation treatment developed to alleviate knee pain associated with osteoarthritis (When nonpharmacologic therapies and simple analgesics such as acetaminophen have failed to provide adequate relief). (polarbearmeds.com)
Syringe2
  • Buy RenehaVis online is a sodium hyaluronate product, comprising a dual-chambered prefilled syringe that enables administration of both high and low molecular weight hyaluronate in a single intra-articular injection. (originalbotox.com)
  • Use the same syringe for both synovial fluid removal and Synvisc injection, ensuring proper hygiene. (polarbearmeds.com)
Osteoarthritis of the knee2
Molecular2
Systemic2
  • Cryotherapy, joint lavage, systemic anti-inflammatories, or intra-articular medications are used to reduce joint inflammation. (wikipedia.org)
  • Intravascular injections of Synvisc may lead to systemic adverse events. (polarbearmeds.com)
Precautions1
Efficacy2
Radiography1
  • Forty three horses older than 2 years with OA in only one joint based on clinical evaluation, intra-articular anaesthesia and imaging (radiography) were included in this study. (biomedcentral.com)
Diclofenac sodium2
  • The FDA approved a submicron low-dose product (Zorvolex) for osteoarthritis that allows treatment at a lower dose than the diclofenac sodium and potassium salts. (medscape.com)
  • This medication was approved in 2009 and is a topical formula of diclofenac sodium in a patented carrier solution that delivers the active medication through the skin, directly to the area of pain. (arthritishealth.today)
Hypersensitivity2
  • Individual intolerance (including history of hypersensitivity) of sodium hyaluronate. (bestpharmbuy.com)
  • Some of the preparations of sodium hyaluronate contain a small amount of chicken protein, therefore, in the treatment of patients with appropriate hypersensitivity, caution should be exercised. (bestpharmbuy.com)
Saline3
  • Contains 22 mg / ml of lightly cross-linked sodium hyaluronate (NaHA) dissolved in physiologically osmolar phosphate buffered saline. (medisport.it)
  • A total of 60 patients with chronic knee pain were randomized to receive 4 mL PRP intra-articularly (IA) in three doses once a week or one 4 mL dose of saline solution IA. (aestheticsadvisor.com)
  • The study will compare single intradiscal injections of high and low dose IDCT with two control groups (saline, Sodium Hyaluronate). (sourcehealthcare.com)
Synvisc3
Gram-positive bacterial proteins1
  • The product is composed of cross-linked sodium hyaluronate and may contain traces of gram-positive bacterial proteins. (medisport.it)
Tissues1
  • The moisturizing injection works from the inside out to give the skin a healthy, youthful appearance by penetrating deep into skin tissues. (singcleanmedical.com)
Clinical2
  • In contrast to the cost- and labor-intensive cultivation and propagation of cells such as MSCs or articular chondrocytes, the clinical use of "minimally processed" autologous BMA that can be prepared in the operation room as a single-step procedure appears straightforward. (hindawi.com)
  • Phillips MW: Clinical trial comparison of intraartic-ular sodium hyaluronate products in the horse. (biomedcentral.com)
Mediators1
  • Additionally, naproxen sodium inhibits prostaglandin synthesis, which are mediators of inflammation so it may exert its therapeutic benefit by decreasing prostaglandins in joint tissue. (arthritishealth.today)
Quaternary ammon1
  • When treating the skin before the injection can not be used disinfectants containing quaternary ammonium salts. (bestpharmbuy.com)
Patients2
Widely1
  • 3 ) Due to the progressive nature of knee osteoarthritis, lifestyle changes tend to prove inadequate and, combined with patient desire to avoid surgical treatment, intra-articular injections are the most widely used option for the treatment of knee osteoarthritis. (e-agmr.org)
Severe1
  • In the case of severe joint pathology such as an osteochondral chip, intra-articular fracture, osteochondritis dissecans lesion, or ligamentous or meniscal injury, arthroscopy may be required to ensure normal function of that joint. (wikipedia.org)
Redness1
  • Redness, sensation of heat and heaviness at the injection site. (bestpharmbuy.com)
Joint12
  • Intra-articular injections of steroid derivatives are the second most common medical intervention for treating painful joint conditions. (medscape.com)
  • Sodium hyaluronate should be gently injected into the joint cavity. (bestpharmbuy.com)
  • 11 - 14 ) However, the effect of intra-articular application of HA may have more mechanical therapeutic mechanisms of action, including absorption, joint lubrication, anti-inflammatory effects, chondroprotection, and proteoglycan synthesis. (e-agmr.org)
  • It is administered by injection directly into the knee joint (intra-articular injection). (koreacosmeticsbn.com)
  • Sodium hyaluronate should be injected for this application only by medical personnel proficient in injection techniques accepted for administering agents into the joint spaces. (medisport.it)
  • Intra-articular injections of 10 mg sodium hyaluronate (Euflexxa) were administered weekly to the subtalar joint for 3 weeks. (unisa.it)
  • Joint pain and stiffness should occur within the next 14 days after the first injection Hyalgan. (beautydermal.com)
  • Articular damage to the ankle joint has a broad range of etiologic processes including traumatic arthritis, primary degenerative osteoarthritis, neuropathic arthropathy, inflammatory arthritis, and infectious arthritis. (faoj.org)
  • Crespine Gel Plus 14mg/ml, 3mg/ml is injected intraarticular as an addition for the Reduction of Pain And Improvement of The Joint Function . (healthwiregeorgia.com)
  • TG-C is to be administered by a single intra-articular injection to the damaged joint area. (sourcehealthcare.com)
  • Adverse reactions to joint injection were assessed. (biomedcentral.com)
  • Thirty-three horses, older than two years with OA located within only one joint were treated intra-articularly with PAAG. (biomedcentral.com)
Needle1
  • If the pain increases during the injection, stop the injection and withdraw the needle. (medisport.it)
Inflammation2
  • Injections are also administered when there is limited movement of the knee or pelvis in a patient who is caused by inflammation. (beautydermal.com)
  • XT-150 is a plasmid DNA that will be injected into the intra-articular space of the affected knee and has been shown to reduce inflammation through cytokine IL-10. (sourcehealthcare.com)
Treatment2
Concentration1
  • The light skincare concentration in the injection would not oxidize, regenerate, or harm even the most delicate skin. (singcleanmedical.com)
Therapeutic1
  • Therapeutic exercises that have been studied include articular stretching and pulley therapy. (medscape.com)
Months1
Solution2
  • Sterile, pyrogen-free solution based on sodium hyaluronate slightly cross-linked with a proprietary chemical binder. (medisport.it)
  • This is a solution for intra-articular injection, the main active component of which is sodium hyaluronate. (beautydermal.com)
Procedure1
  • The use of strict aseptic techniques in administration must be adhered to during the injection procedure. (polarbearmeds.com)
Application1
  • It must be administered by a health professional since its application is intra-articular (inside the synovial capsule of the knee). (originalbotox.com)
Skin6
  • This is light gel-type toner for brightening and glowing effect that helps to be nutritious and smoothed skin with niacinamde, idebenone, Sodium hyaluronate, Rosa damascena flower extract, and Oenothera biennis (Evening primrose) flower extract. (koreacosmeticsbn.com)
  • Sodium hyaluronate has moisturizing benefits when applied topically to skin tissue. (koreacosmeticsbn.com)
  • The acid provides a smoother yet softer skin texture by lifting and supporting sagging skin Nearly all skin types are appropriate for the best HA filler injection, and men and women both benefit from it. (singcleanmedical.com)
  • Our HA filler injection supplier encourages skin cell regeneration by protecting the skin's barrier and adding additional moisture. (singcleanmedical.com)
  • Pure HA filler injection for skin that provides deep skin hydration and nourishment. (singcleanmedical.com)
  • With our HA-filler injections, you can take control of the health of your skin and preserve its elasticity and attractiveness. (singcleanmedical.com)
Current1