Smooth muscle relaxation in blood vessels relaxation modifies serum muscle relaxation. Medical search. Frequent questions

Also, a vascularization strategy using co-culture with endothelial cells (ECs) and fibroblasts improved the survival of the bioengineered skeletal muscle tissues 20 , 21 . (nature.com)
Convincing data have been presented to show that production of reactive oxygen species (ROS) occurs in nonphagocytic cells, including endothelial cells ( 8 ), vascular smooth muscle cells ( 9 ), and aortic adventitial fibroblasts ( 10 ), and superoxide anion has a variety of biological functions that accompany induction of gene expression ( 11 ), cellular proliferation ( 12 ), apoptosis ( 13 , 14 ), and hypertrophy ( 15 ). (diabetesjournals.org)
This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. (theodora.com)
Endothelin produced by vascular endothelial cells is a potent vasoactive peptide that elicits prolonged contraction of vascular smooth muscle cells. (silverchair.com)

Sildenafil -- a phosphodiesterase type V inhibitor -- produces smooth muscle relaxation in blood vessels, which accounts for its effects in many cases of erectile dysfunction and also in pulmonary arterial hypertension. (medpagetoday.com)
It results in the inability to properly store magnesium, causing blood vessels to constrict, elevated blood pressure, and coronary arterial spasm, all of which can result in a heart attack. (drsircus.com)
Arterial blood gas levels (through an indwelling line [eg, umbilical arterial catheter or preductal peripheral arterial line]): To assess the pH, partial pressure of carbon dioxide (PaCO 2 ) and the partial pressure of oxygen (PaO 2 ) which might be higher in the preductal arterial line. (medscape.com)

Thromboxanes regulate blood clotting by causing constriction of blood vessels, and the aggregation of platelets (so they stick together), which are early steps in blood clotting. (healthyeatingdr.com)

usually associated with trazodone use, cocaine abuse, and sickle cell disease, may cause penile fibrosis and lead to ED by causing fibrosis of the corpora cavernosa and thus impairment of the penile blood flow necessary for erection. (msdmanuals.com)

Papaverine, when injected in penile tissue, causes direct smooth muscle relaxation and consequent filling of the corpus cavernosum with blood resulting in erection. (wikipedia.org)
Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. (theodora.com)

Oral administration of L. murinus to SHRs for 2 weeks significantly inhibited blood pressure elevation and improved endothelium-dependent vasodilation but did not attenuate enhanced vascular contraction in SHR mesenteric arteries. (bvsalud.org)
It was found that thoracic ducts isolated from adult (10-14 wk old) spontaneously hypertensive rats (SHRs) exhibited increased agonist-mediated contraction compared with age-matched Wistar-Kyoto (WKY) rats, whereas lymphatic contractions in younger (4 wk old) SHRs, exhibiting normal blood pressure, were no different compared with age-matched control rats. (bvsalud.org)
There are many different prostaglandins with wide ranging roles such as the sensation of pain, inflammation, regulation of pregnancy and birth, control of blood pressure, secretion of stomach acid, contraction and relaxation of smooth muscle. (healthyeatingdr.com)
Calcium is very essential in muscle contraction, oocyte activation, building strong bones and teeth, blood clotting, nerve impulse, transmission, regulating heart beat and fluid balance within cells. (researchgate.net)

Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. (theodora.com)

[4] Some forms of EDS result in a normal life expectancy , but those that affect blood vessels generally decrease it. (wikipedia.org)
blood flow is increased when blood vessels dilate due to a decrease in vascular resistance (Siddiqui, 2011). (aopwiki.org)
[1] Previous studies of the drug's cardiovascular effects have reported a marked decrease in blood pressure. (silverchair.com)
[10,11] In animals, a decrease in blood pressure has been observed in association with a decrease in peripheral vascular resistance. (silverchair.com)

In the thoracic aorta of OLETF rats, endothelium-dependent relaxation was markedly attenuated compared with that of control (LETO) rats in association with a significant increase in superoxide production (2,421.39 ± 407.01 nmol · min −1 · mg −1 ). (diabetesjournals.org)

Raynaud's phenomenon -- which causes tiny blood vessels in the skin to spasm in response to cold temperatures or stress -- occurs in almost all cases of scleroderma, an autoimmune disease, the researchers noted. (medpagetoday.com)

Hyperlipidemia, characterized by the abnormal blood lipid profiles, is one of the dominant factors of many chronic diseases such as diabetes, obesity, and cardiovascular diseases (CVD). (hindawi.com)
In 2013, the American Heart Association reported that proportions of American adults aged 20 or above had abnormal blood lipid serum profile (details are shown in Table 1 ) [ 4 ]. (hindawi.com)
Average percentage of abnormal blood lipid levels among Americans at age 20 or above [ 4 ]. (hindawi.com)

Guaranteeing our products are all-natural and non-GMO (genetically modified organisms). (pharmstrong.com)

While EPA and DHA reduced serum triglycerides, and also reduced the risk of coronary heart disease such as heart attacks. (healthyeatingdr.com)

TPR), the resistance to blood flow offered by the peripheral circulation, and blood pressure through relaxation of vascular smooth muscle cells (VSMCs) (Siddiqui, 2011). (aopwiki.org)

More importantly, the bioprinted constructs with neural cell integration facilitate rapid innervation and mature into organized muscle tissue that restores normal muscle weight and function in a rodent model of muscle defect injury. (nature.com)
The formation of new vessels in the hypoxic area restores blood flow, provides oxygen and nutriments to the surviving cells, and promotes the migration and engraftment of new cells. (elifesciences.org)

If the blood vessels are capable of dilating, a strong erection should develop within 5 minutes. (medscape.com)

The effects of propofol on endothelin-1-induced intracellular signaling in an aortic smooth muscle cell line, A10 cells, were examined. (silverchair.com)

In this study, we examined whether an alteration in the microbiota affects blood pressure and intestinal permeability in spontaneously hypertensive rats (SHRs). (bvsalud.org)
High blood pressure affects blood vessels throughout the body, including those that feed the kidneys. (blimpt.com)

Characterized by an influx of white blood cells, redness, heat, swelling, pain, and dysfunction of the organs involved, inflammation has different names when it appears in different parts of the body. (drsircus.com)
Elevated blood sugar and inflammation, which damage collagen and interfere with its production. (lifeextension.com)

However, these agents failed to modify the secretion elicited by high Ca2ϩ in nanomolar concentrations of the antiestrogen ICI 182,780 glands treated with the ionophore A-23187 (calcimycin), sug- (fulvestrant). (drugstodaypdf.com)

The atherosclerotic process is accelerated by a myriad of factors, such as the release of inflammatory chemokines and cytokines, the generation of reactive oxygen species (ROS), growth factors, and the proliferation of vascular smooth muscle cells. (hindawi.com)
These constructs (mm 3 -cm 3 scale) consisted of tens to hundreds of long parallel myofiber bundles, containing densely packed, highly viable, and aligned muscle cells. (nature.com)
In physiological systems, active ROS levels, which can be produced in healthy smooth muscles, endothelial and adventitious cells in the systemic and pulmonary vasculatures are responsible for routine regulation of cellular and physiologic responses [7]. (heraldopenaccess.us)
in villous and extravillous trophoblasts, the trophoblast basement membrane, the endothelial basal lamina, foetal blood vessels, foetal and maternal red blood cells, and amnionic cells. (angiogenesis-blog.com)
In order to identify cells immunopositive for angiogenin, we used markers for trophoblast, vascular endothelial and smooth muscle cells, haematopoietic cells, angiogenic status, and proliferation. (angiogenesis-blog.com)
These results suggest that propofol inhibits endothelin-1-induced intracellular signaling in vascular smooth muscle cells. (silverchair.com)
HN - 2008 BX - Granulosa Cells, Cumulus MH - Coronary Sinus UI - D054326 MN - A07.231.908.194.500 MS - A short vein that collects about two thirds of the venous blood from the MYOCARDIUM and drains into the RIGHT ATRIUM. (bvsalud.org)

Check the level of protein, glucose, and blood in the urine. (blimpt.com)
Blood glucose test. (blimpt.com)
Since the kidneys are the ones that filter out the blood residues, and diabetes is manifested by too much glucose in the blood, the kidney function is overstimulated. (blimpt.com)

Thyroid hormones affect cardiac output and vascular resistance, and thus can modify kidney perfusion. (medscimonit.com)

This study examined the efficacy of quercetin in preventing the hypoxia-mediated increase in Phosphodiesterase-5 (PDE-5) levels in the lung, leading to the diminution of alveolar smooth muscles vasoconstriction and curtailed transvascular leakage. (heraldopenaccess.us)
Research had also confirmed that exacerbation in ROS production due to hypoxia is amongst major factors for the occurrence of vasoconstriction in the smooth muscles of lung endothelium [5,6]. (heraldopenaccess.us)
In order to standardize the care of patients with COPD and present evidence-based recommendations, the National Heart, Lung, and Blood Institute (NHLBI) and the World Health Organization (WHO) launched the Global Initiative for Chronic Obstructive Lung Disease (GOLD) in 2001. (basicmedicalkey.com)

MAIN OUTCOME MEASURES Diameter of the proximal and distal segments of the epicardial coronary arteries and coronary blood flow. (bmj.com)

Because diabetes and high blood pressure are responsible for two-thirds of the cases of chronic kidney failure, following proper treatment to control these conditions also means a diminished risk of renal function. (blimpt.com)

Neural input into this bioprinted skeletal muscle construct shows the improvement of myofiber formation, long-term survival, and neuromuscular junction formation in vitro. (nature.com)

These approaches have achieved bioengineered skeletal muscle tissue fabrication with cellular alignment in vitro, and some showed a degree of therapeutic potential in vivo. (nature.com)
The placenta assumes several roles essential for successful pregnancy: it is an exchanger between the foetal and maternal blood circulation and also an endocrine tissue ([13], for review), and it provides local immune protection for the foetus. (angiogenesis-blog.com)

CBD Gel Roller - The fastest way to soothe overworked muscles and joints is to target them directly with a CBD and menthol-infused topical product that penetrates to provide prompt relief. (pharmstrong.com)
[4] Physical therapy and bracing may help strengthen muscles and support joints. (wikipedia.org)

Blood tests, blood pressure monitoring, and DTPM of the renal cortex were performed. (medscimonit.com)
Lymph capillary network can be expected to alter blood pressure via regulating interstitial electrolyte and volume balance. (bvsalud.org)
It is concluded that lymphatic contractile function was enhanced in hypertensive model rats, which could be mediated by dysregulation of the ROCK pathway possibly through RGS16.NEW & NOTEWORTHY Lymph capillary controls interstitial electrolyte and volume balance, which may blunt increased blood pressure. (bvsalud.org)
Women who are pregnant should be warned about things such as pre-labor rupture of membranes, drop in blood pressure with anesthesia, precipitate birth (very fast, active labor), malposition of bleeding, and more. (wikipedia.org)
When vasodilation is impaired due to decreased NO availability, SVR and blood pressure become elevated. (aopwiki.org)
When vasodilation is impaired, SVR increases, in turn increasing blood pressure. (aopwiki.org)
Omega 3 fatty acids have been shown to reduce blood pressure and can be incorporated into your diet by eating oily fish or seeds such as chia seeds, flaxseeds and nuts. (healthyeatingdr.com)
Three-week treatment of SHRs with rosiglitazone and/or enalapril significantly reduced blood pressure, insulin resistance, fasting insulin, and ET-1 levels and increased adiponectin levels to values comparable with those observed in vehicle-treated WKY controls. (diabetesjournals.org)
Blood pressure decreases when propofol is administered. (silverchair.com)
Blood pressure control. (blimpt.com)
Thus, treating elevated blood pressure, which involves quitting smoking, following a dietary diet and regular movement, is essential for the maintenance of renal function, suggests nephrologist in Gurgaon . (blimpt.com)

Increasing ALA, made no significant difference to blood clots of the coronary arteries supplying the heart (coronary events), but slightly reduced cardiovascular events (diseases related to blood vessels such as clots and rhythm problems). (healthyeatingdr.com)

I: The distress of heart responsiveness to the blood of conditions that cannot Excrete together determined by the common health. (augenta.net)
10,000-fold more potent for PDE5 than for PDE3, an enzyme found in the heart and blood vessels. (theodora.com)
Angina Decubitus/Angina pectoris (Latin for squeezing of the chest) - is chest pain, discomfort, or tightness that occurs when an area of the heart muscle is receiving decreased blood oxygen supply. (rxharun.com)
The lack of oxygen rich blood to the heart is usually a result of narrower coronary arteries due to plaque buildup, a condition called atherosclerosis. (rxharun.com)
This type is caused by a blood clot that blocks the blood vessel, and it will cause a heart attack if the blockage isn't removed. (rxharun.com)
Your heart muscle needs a constant supply of oxygen. (rxharun.com)
The coronary arteries carry blood containing oxygen to the heart. (rxharun.com)
When the heart muscle has to work harder, it needs more oxygen. (rxharun.com)

Autoimmune anti-HIV-1gp120 antibody with antiidiotype-like activity in sera and immune complexes of HIV-1-related immunologic thrombocytopenia. (jci.org)

In this study, we examined lymph vessel function focusing on contractile response in hypertensive rats. (bvsalud.org)
When compared with WKY control rats, 12-week-old vehicle-treated SHRs were hypertensive, overweight, and insulin resistant, with elevated fasting levels of insulin and ET-1 and reduced serum adiponectin levels. (diabetesjournals.org)

The cholesterol-fed LDLR-/- mice offer a new model for the study of environmental and genetic factors that modify the processes of atherosclerosis and xanthomatosis. (jci.org)
Symptoms of angina occur when the coronary arteries are narrowed or blocked by atherosclerosis or by a blood clot. (rxharun.com)

CBD Balm - Our thick, skin-smoothing balm features only five holistic ingredients, including organic beeswax, organic lavender essential oil, and organic eucalyptus essential oil. (pharmstrong.com)
In general, people with this variant have skin that is soft, smooth, and velvety and bruises easily, and may have chronic muscle and/or bone pain. (wikipedia.org)

The foetal circulation extends through the placental villous tree, bathing in maternal blood that enters the intervillous space utero-placental arteries. (angiogenesis-blog.com)

Secondary endpoints included change in the absolute number of attacks, the Raynaud's Condition Score, the duration of attacks, the pain score, endothelial dysfunction, and serum biomarker levels. (medpagetoday.com)

Endothelial dysfunction is a disease of the endothelial lining of the small arterioles that reduces the ability to vasodilate when needed to increase blood flow. (msdmanuals.com)

It is also commonly used in cryopreservation of blood vessels along with the other glycosaminoglycans and protein suspensions. (wikipedia.org)

Blood and urine samples were collected during both studies and vascular tone was measured using laser Doppler imaging. (cambridge.org)
The kidneys perform the important function of filtering excess residues and fluids from the blood, which are then excreted through the urine. (blimpt.com)
Capillary vessels become more porous and begin to escape from residues and proteins that should not be filtered normally reach the urine, says nephrologist in Noida . (blimpt.com)

Sex-based differences in pain recognition and drug responses, fluid balance, and the blood-brain barrier are recognized but their impact on migraine is not well studied. (frontiersin.org)

Autoimmune antiidiotype-like antibody (Ab2) directed against anti-HIV-1gp120 (Ab1) was found in high titer in the sera of 10 consecutive homosexual and 11 narcotic addict HIV-1-related immunologic thrombocytopenia (HIV-1-ITP) patients, was barely detectable in 10 nonthrombocytopenic HIV-1 sero-positive individuals, and was not detectable in 5 normal subjects by use of a solid-phase RIA. (jci.org)
At the single cell level, estrogens modified the total catecholamine release with high and low affinity, re- kinetics of exocytosis at nanomolar range. (drugstodaypdf.com)

While host nerve integration and formation of NMJs were evident within the implanted skeletal muscle constructs, we observed that the constructs did not support the full restoration of defected muscles at 8-week post-implantation, which is likely due to the delayed integration of host nerve. (nature.com)

9,000-fold more potent for PDE5 than for PDE8, PDE9, and PDE10 and 14-fold more potent for PDE5 than for PDE11A1, an enzyme found in human skeletal muscle. (theodora.com)

The term angiogenesis was coined by Arthur T. Hertig in 1935 to describe the formation of new blood vessels in the placenta [11]. (angiogenesis-blog.com)

It receives blood from a vein in the nasal cavity, runs backwards, and gradually increases in size as blood drains from veins of the brain and the DURA MATER. (bvsalud.org)

Papaverine is also present in combinations of opium alkaloid salts such as papaveretum (Omnopon, Pantopon) and others, along with morphine, codeine, and in some cases noscapine and others in a percentage similar to that in opium, or modified for a given application. (wikipedia.org)

We previously showed that bioprinted human skeletal muscle constructs were able to form multi-layered bundles with aligned myofibers. (nature.com)
These results suggest that the 3D bioprinted human neural-skeletal muscle constructs can be rapidly integrated with the host neural network, resulting in accelerated muscle function restoration. (nature.com)
This strategy has been applied to develop a three-dimensional (3D) human muscle model with endothelium specificity and endomysium for the study of fibrosis 22 . (nature.com)
We also demonstrated the feasibility of using these 3D bioprinted human skeletal muscle constructs to treat critical-sized muscle defect injuries with structural and functional restoration in a rodent model 2 . (nature.com)

However, the function of lymphatic vessel in hypertension is poorly understood. (bvsalud.org)

The sildenafil was in a modified-release formulation to allow once-daily dosing, they noted, and for this study, Raynaud's phenomenon was defined as episodic digital pallor followed by cyanosis, erythema, or both in response to cold or emotion. (medpagetoday.com)

Offered in mint, orange, and natural flavor, when you administer these potent drops under your tongue, the beneficial compounds begin absorbing into your sublingual blood vessels, bypassing typical digestion to deliver quick results. (pharmstrong.com)
20% of the original mass invariably results in functional impairment with limited regeneration capacity, which requires reconstructive surgical procedures such as autologous muscle flap transfers 1 . (nature.com)

It measures the amount of residues resulting from muscle activity. (blimpt.com)

Health Status: The risk of point of the beta-oxidation, series, or blood as not Attached by the serous or by more age dysproteinemias. (augenta.net)

Anatomy67

Organisms16

Diseases10

Chemicals and Drugs97

Analytical, Diagnostic and Therapeutic Techniques and Equipment21

Psychiatry and Psychology4

Phenomena and Processes40

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena1

Information Science4

Health Care1

Endothelial cells4

Arterial3

Platelets1

Corpora cavernosa1

Corpus cavernosum2

Contraction4

Penile1

Decrease4

Endothelium-dependent1

Spasm1

Lipid3

Genetically modified1

Coronary heart d1

VSMCs1

Restores2

Erection1

Aortic1

Affects2

Inflammation2

Secretion1

Cells7

Glucose3

Vascular resistance1

Lung3

Epicardial1

Kidney1

Survival1

Tissue2

Joints2

Pressure11

Diseases1

Heart8

Immune1

Rats2

Atherosclerosis2

Skin2

Circulation1

Levels1

Flow1

Protein1

Urine3

Fluid balance1

High2

Nerve1

Found1

Formation1

Increases1

Percentage1

Human4

Function1

Response1

Results2

Amount1

Status1