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  • genome
  • Many viruses encode their genetic information using an RNA genome. (wikipedia.org)
  • The reverse transcriptase makes a DNA copy of the LINE RNA that can be integrated into the genome at a new site. (wikipedia.org)
  • For example, after conversion of retroviral RNA into DNA inside a host cell, the newly produced retroviral DNA is integrated into the genome of the host cell. (wikipedia.org)
  • sequences
  • In nature complementarity is the base principle of DNA replication and transcription as it is a property shared between two DNA or RNA sequences, such that when they are aligned antiparallel to each other, the nucleotide bases at each position in the sequences will be complementary, much like looking in the mirror and seeing the reverse of things. (wikipedia.org)
  • inhibition
  • The inhibition occurred at two points in the viral life cycle, after fusion and before reverse transcription and during transcription of viral RNA from integrated provirus. (jimmunol.org)
  • inhibit
  • During the viral life cycle, viral RNA is present in the cytoplasm of cells after fusion and before reverse transcription, which presents a target that when acted on can inhibit infection before proviral integration. (jimmunol.org)
  • complementarity
  • In biotechnology, the principle of base pair complementarity allows the generation of DNA hybrids between RNA and DNA, and opens the door to modern tools such as cDNA libraries. (wikipedia.org)
  • While most complementarity is seen between two separate strings of DNA or RNA, it is also possible for a sequence to have internal complementarity resulting in the sequence binding to itself in a folded configuration. (wikipedia.org)