Loading...
  • Mice
  • One application of the dorsal skin chamber in mice used two-photon confocal microscopy to examine tumor gene expression, angiogenesis, and physiology in a green fluorescent protein (GFP)-expressing tumor ( 1 ). (pnas.org)
  • tumor
  • For example, one of his techniques involves a tiny glass window implanted in the skin of a mouse that allows scientists to track individual cancer cells as they spread a tumor site and attack other parts of the body. (yu.edu)
  • Single tumor cells, expressing green fluorescent protein, were seeded on the brain image through a scalp skin-flap. (pnas.org)
  • Lung tumor microfoci representing a few cells are viewed through a skin-flap over the chest wall, while contralateral micrometastases were imaged through the corresponding skin-flap. (pnas.org)
  • A skin-flap over the liver allowed imaging of physiologically relevant micrometastases originating in an orthotopically implanted tumor. (pnas.org)
  • Possible future technical developments are suggested by the image, through a lower-abdominal skin-flap, of an invasive prostate tumor expressing both red and green fluorescent proteins in separate colonies. (pnas.org)
  • penetration
  • However, transdermal drug delivery often faces the problem of insufficient or no penetration of active pharmaceutical substances through the skin. (omicsonline.org)
  • The aim of this contribution is to describe advantages and disadvantages of transdermal administration of drugs and the structure of the skin as a barrier preventing penetration of any heterogeneous substances into the body. (omicsonline.org)
  • Cancer
  • This technique could one day be used for assessing the effectiveness of specific drugs in preventing cancer from metastasizing. (yu.edu)
  • levels
  • Following a 1 gram dose and utilizing a special skin window technique to determine levels of the antibiotic, it was noted that therapeutic levels were found in the interstitial fluid. (nih.gov)
  • Following a 1-gram dose and utilizing a special skin window technique to determine levels of the antibiotic, it was noted that therapeutic levels were.Augmentin, Co-amoxiclav advantages, disadvantages, FDA indications and off-label uses, interesting facts.Antibiotic Resistance, Part 1: Gram-positive Pathogens Catherine M.Moderate-risk patients who are allergic to ampicillin and amoxicillin. (mondaymorningmusings.me)
  • basic
  • Covering all aspects of skin disease from basic science through pathology and epidemiology to clinical practice, the text is recognized for its unparalleled coverage of diagnosis. (rooksdermatology.com)
  • important
  • The most important is the outermost layer of epidermis, the horny layer ( stratum corneum , SC), which is in fact the skin barrier. (omicsonline.org)
  • animals
  • 1970). When animals immunized in this fashion were skin tested 5-7 days later, sites of antigenic challenge developed intradermal infiltrates containing large numbers of basophilic granulocytes, as well as lymphocytes (H. Dvorak et al . (springer.com)
  • include
  • The ideal properties of a molecule that effectively penetrates through the SC include drug solubility, penetrability (drug gets into the skin), permeation (drug passing through the skin), and resorption in blood or lymphatic vessels. (omicsonline.org)