• Recording MF activity during the PREP sessions was more difficult than I imagined, as there were several confounding factors limiting my analysis of the data, with the two more important as follows: 1) The trainers led the students through about 5 different Focus levels (i.e., different audio frequencies) in less than one hour, which led to very complex responses in the physiological markers. (indiana.edu)
  • Electrodes are placed on the student's fingers to measure skin temperature, galvanic skin response (GSR) and skin potential voltage. (indiana.edu)
  • We introduce materials, device designs, wireless power delivery and communication strategies, and overall system architectures for skin-like, battery-free sensors of temperature and pressure that can be used across the entire body. (northwestern.edu)
  • Dr. Davis is interested in physiological responses to body-core temperature stresses and local temperature stresses placed on the body. (smu.edu)
  • Decrease of skin blood flow in fingers to 6.3 milligrams per 100 grams of tissue per minute, an increase in peripheral resistance, and a drop of skin temperature were observed. (cdc.gov)
  • Earlier research has shown that the brain has an internal spatial image of the body, which is continuously updated based on touch, pain, temperature and pressure - known as the somatosensory system - received from skin, joints and muscles, as well as from visual and auditory signals. (newswise.com)
  • Accordingly, Exergen, incorporating a patented and well-proven arterial heat balance method, developed instrumentation for non-invasive arterial temperature assessment on the skin over temporal artery. (exergen.com)
  • The TAT detects the heat naturally emitting from the skin surface over the temporal artery using a patented arterial heat balance system to automatically account for the effects of ambient temperature on the skin. (exergen.com)
  • Using a powerful concentration of sandalwood oil (at a much higher intensity that you would find in the average bottle), researchers measured an array of physiological responses such as respiration rate, skin temperature, blood pressure, and the like. (naturallivingideas.com)
  • These temperature-sensitive nociceptor neurons become activated when the temperature at their free endings in the skin or mucosae reaches noxious levels, provoking acute pain and rapid avoidance reflexes. (oxfordhandbooks.com)
  • In humans at rest, a skin temperature of around 33°C is experienced as thermoneutral, with lower temperatures felt as cool/cold and higher temperatures as warm/hot (Vriens, Nilius, & Voets, 2014 ). (oxfordhandbooks.com)
  • This study suggests that pericytes represent a potent stem cell population in the skin that is capable of modifying the ECM microenvironment and promoting epidermal tissue renewal from non-stem cells, a previously unsuspected role for pericytes. (nih.gov)
  • The extract also inhibited the nuclear translocation of NF-κB in an epidermal skin model, and induced the expression of VEGF-A to promote the microcirculation in a dermal microtissue model. (frontiersin.org)
  • The permeability of ondansetron from an aqueous suspension through shed snake skin as a model membrane was very low and in order to improve it, several enhancers were tested. (biomedsearch.com)
  • The permeability coefficient increased after pretreatment of the shed snake skin with Azone, oleic acid or lauryl alcohol. (biomedsearch.com)
  • The ultrasonic wave stimulates skin tissue and improves permeability of the membrane to promoted collagen tissue, reduces wrinkles and fine lines Ultrasound will also lift the skin resulting in a younger and healthier look. (sylvancompany.com)
  • We then present the main arguments that have been used to provide theoretical support for polygraph testing and evaluate them in relation to current understanding of human psychological and physiological responses. (nap.edu)
  • and it is difficult to disentangle the roles of physiological responses, interrogators' skill, and examinees' beliefs in order to make clear attributions of practical results to the validity of the test. (nap.edu)
  • Pulse and respiration, as two indispensable components of vital signs, can provide both an accurate assessment of the physiological state and remarkable insights into the diagnosis and prognosis of related diseases ( 12 - 21 ). (sciencemag.org)
  • citation needed] In other applications, excess skin is grown purposely by expansion on the back or the buttocks, so that it can be harvested later for transplantation to another site where skin was lost due to trauma, extensive wounds, surgery, burns, etc. (wikipedia.org)
  • This work is revealing that the control of body and organ size does not reside in any specific cellular or molecular mechanism but that it is a systems property in which cellular, physiological and environmental signals all contribute in inextricable ways to produce the final phenotype. (duke.edu)
  • Some people experience prickling skin, hallucinations, dizziness, or even hiccups as signals that a brutal migraine is on the way. (spiritualityhealth.com)
  • However, most reported textile electronics can either periodically target a single physiological signal or miss the explicit details of the signals, leading to a partial health assessment. (sciencemag.org)
  • To date, most wearable electronics for detecting subtle physiological signals are based on ultrathin substrates such as polyethylene terephthalate, polydimethylsiloxane, polyimide, glass, and silicone ( 22 - 26 ). (sciencemag.org)
  • Of course, longevity is a genetic, hereditary phenomenon. (baltictimes.com)
  • Here, we examined whether autophagy contributes to the longevity of NMRs by assessing the effects of the PI3K/Akt pathway inhibitor LY294002 and the autophagy inhibitor chloroquine (CQ) on autophagy and apoptosis in NMR skin fibroblasts. (pubmedcentralcanada.ca)
  • That group has also shown that NMRs have evolved a higher concentration of high-molecular-mass hyaluronan in the skin to provide the skin elasticity needed for life in underground tunnels, which may confer added benefits of cancer resistance and longevity [ 12 ]. (pubmedcentralcanada.ca)
  • Free radical concept of aging discusses the biochemical phenomenon of aging. (hubpages.com)
  • Free radicals are not new to the body and are a part of the destruction in the biochemical and physiological process in tissue repair and cellular replication as people age. (hubpages.com)
  • Detailed biochemical profiling of mammalian target of rapamycin signaling in tumors, skin, and peripheral blood mononuclear cells (PBMCs), after a single administration of 5 mg/kg RAD001, indicated that RAD001 treatment blocked phosphorylation of the translational repressor eukaryotic initiation factor 4E-binding protein 1 and inactivated the translational activator ribosomal protein S6 kinase 1 (S6K1). (aacrjournals.org)
  • LAMA5 was of particular interest as we had previously shown that it promotes skin regeneration both in vitro and in vivo. (nih.gov)
  • LPS-Stimulated Human Skin-Derived Stem Cells Enhance Neo-Vascularization during Dermal Regeneration. (nih.gov)
  • Thus, current and future research efforts of his laboratory are geared towards using adult skin-derived ABCB5+ stem cells as a transplantable cell source for novel therapeutic applications in tissue engineering and regeneration, and for stem cell-based modulation of transplant allograft rejection and autoimmune disorders. (lifeboat.com)
  • Frank and his colleagues were interested in a particular protein called ABCB5, which is expressed on the surface of some progenitor skin cells and has been shown to confer cancer drug resistance to melanoma. (lifeboat.com)
  • His laboratory has cloned and characterized a novel human ATP-binding cassette (ABC) transporter, ABCB5, which marks mesenchymal stem cell (MSC) subpopulations in human and murine skin. (lifeboat.com)
  • His work has demonstrated a unique regulatory role of ABCB5 in the newly recognized phenomenon of stem cell fusion, and in cell fusion-dependent growth and differentiation. (lifeboat.com)
  • The identification and characterization of ABCB5 P-glycoprotein as a marker of adult skin-associated stem cells has allowed Markus to initiate studies regarding the differentiation plasticity and immunomodulatory capacity of this unique cell subset in vitro and in vivo. (lifeboat.com)
  • In tandem with fundamental approaches to further establish ABCB5 as an identifier of melanoma stem cells and to characterize the functional roles of ABCB5 in physiological and cancer stem cells, Dr. Frank's laboratory explores the clinical relevance of ABCB5 as a biomarker of melanoma progression, prognosis, and outcome, and to investigate the therapeutic efficacy of ABCB5 targeting in preclinical animal models of human malignant melanoma. (childrenshospital.org)
  • 35 degrees C, potentially reducing respiratory water loss by approximately 65% at T(a)=10 degrees C to approximately 30% at T(a)=35 degrees C. Cutaneous evaporative cooling was significant for both species, with skin resistance decreasing as T(a) increased. (nih.gov)
  • The Crested Pigeon had a lower skin resistance than the Brush Bronzewing at T(a)=45 degrees C. The Brush Bronzewing had apparently reached its maximum cutaneous water loss at 30 degrees C and relied on panting to cool at higher T(a). (nih.gov)
  • Its morphological features suggest that it is an active, inherently programmed phenomenon, and it has been shown that it can be initiated or inhibited by a variety of environmental stimuli, both physiological and pathological.The structural changes take place in two discrete stages. (nih.gov)
  • Since it has been suggested that 40-Hz EEG activity is the physiological expression of focused arousal (Sheer, 1989), the increase of 40-Hz activity in high hypnotizables during hypnosis was interpreted as indicating the greater capacity of these subjects in focussing of attention on relevant stimuli. (mcmaster.ca)
  • A compression/ischemia-induced (differential) nerve block in conjunction with repeated quantitative sensory testing of A-delta and C-fibre function using cold and warm stimuli was used to assess which nerve fibre population that contributes to pain at perception threshold level using 1 s (vF1) and 10 s (vF10) von Frey filament stimulation of the skin. (degruyter.com)
  • In addition to the effects of chronological ageing, sunlight exposure and other environmental and endogenous stimuli, the climacteric appears to exert some dramatic consequences on skin biology and aspect. (uliege.be)
  • Furthermore, by examining how Purkinje cells respond to two distinct conditional stimuli and to a compound stimulus, we provide evidence that could potentially help explain the somewhat counterintuitive overexpectation phenomenon, which was derived from the Rescorla-Wagner model. (pnas.org)
  • The superficial temporal artery demonstrates the necessary requirements for the skin thermometry method: it is easily accessible, contains no mucous membranes, and notably, it has no or very few arteriovenous anastomoses (AVA).1,2 Lack of AVA's means that perfusion rate is reliable under essentially all conditions, and the blood flow is relatively free of vasomotor control in response to thermomoregulatory stimuli. (exergen.com)
  • Continuum mechanics approaches can be used to model skin growth during tissue expansion and non-linear finite element methods can be used to computationally simulate different tissue growth scenarios. (wikipedia.org)
  • In future experiments, I hope to measure both MF activity and REG output to determine if these methods are measuring the same phenomenon. (indiana.edu)
  • A test with good construct validity is one that uses methods that are defensible in light of the best theoretical and empirical understanding of those mechanisms, the external factors that may alter the mechanisms and affect test results, and the measurement issues affecting the ability to detect the signal of the phenomenon being measured and exclude extraneous influences. (nap.edu)
  • Equally, studies of the physiological and genetic mechanisms underpinning colour variation are burgeoning. (royalsocietypublishing.org)
  • Confidence in polygraph testing, especially for security screening, therefore also requires evidence of its construct validity, which depends, as we have noted, on an explicit and empirically supported theory of the mechanisms that connect test results to the phenomenon they purport to be diagnosing. (nap.edu)
  • Although phenomena associated with the model have previously been linked to nucleo-olivary inhibition, many questions regarding the neural mechanisms underlying the model still remain. (pnas.org)
  • Neural mechanisms for several phenomena related to the Rescorla-Wagner model have already been proposed ( 5 ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ - 16 ). (pnas.org)
  • His laboratory research focuses on the physiological and pathological roles of the human P-glycoprotein family of ATP-binding cassette (ABC) transporters. (lifeboat.com)
  • However, a combination of family history and CB IgE and skin assessment may be used to identify babies at high risk of allergy for participation in prevention studies. (nih.gov)
  • The phenomena of perceptual alterations in hypnosis as those of positive and negative hallucinations are some of the most compelling experiences of highly hypnotizable subjects. (mcmaster.ca)
  • Chemical peels, for instance, are known for their ability to reduce the appearance of fine lines under the eyes and around the mouth, wrinkles caused by sun damage and aging, mild scars, certain types of acne, age spots, freckles, and dark patches (such as melasma caused by pregnancy and birth control pills) while improving the overall look and feel of skin. (thefaceexperts.com)
  • Skin microcirculation consists of two vascular plexuses: superficial at a depth of 400-500 μm and deep located at a depth of 1.9 mm below the skin surface. (termedia.pl)
  • Skin microcirculation may be affected both in systemic pathologies and specific skin disorders. (termedia.pl)
  • Septic and allergic shocks, global hypoxia, hypoxia-reperfusion injuries, coagulation disorders and activation of the immune system affect the skin microcirculation function. (termedia.pl)
  • Currently, several non-invasive techniques are available to assess the skin microcirculation. (termedia.pl)
  • During a hyperinsulinemic clamp, we measured leg blood flow with venous occlusion plethysmography, skin capillary density with capillaroscopy, endothelium-(in)dependent vasodilatation of skin microcirculation with iontophoresis of acetylcholine and sodium nitroprusside combined with laser Doppler fluxmetry, and skin vasomotion by Fourier analysis of microcirculatory blood flow. (jove.com)
  • The skin microcirculation is impaired. (uliege.be)
  • We further showed that skin pericytes could also act as mesenchymal stem cells, exhibiting the capacity to differentiate into bone, fat, and cartilage lineages in vitro. (nih.gov)
  • In this study, stem cells derived from human skin (SDSC) were activated with LPS and seeded in a commercially available dermal substitute to examine vascularization in vivo. (nih.gov)
  • Adrenaline, which in humans is produced in two small beanlike glands that sit atop the kidneys, not only causes the contraction of skin muscles but also influences many other body reactions. (scientificamerican.com)
  • For example, the "age champions" absorb fats and glucose differently, their skin is aging much more slowly, and they are less prone to cardiovascular diseases and diabetes. (baltictimes.com)
  • Lasers , which help tighten loose skin and even out skin tone (one of the most identifiable signs of aging in most studies). (thefaceexperts.com)
  • Skin aging, like most physiological phenomena, is the result of many things. (thefaceexperts.com)
  • the old symbol of eternity), skin aging and the Church's position on the issue of elderly care, and explain how this palliative responsibility is ontological and bioethical grounded for the elderly and not someone else's interests. (omicsonline.org)
  • The non-invasive method applied can be useful for objective and quantitative investigation of age-related changes in skin fatigue and evaluation of the effects of cosmetic and anti-aging topical products. (nih.gov)
  • Studies with human subjects in clinical sleep laboratories and in adjustable hospital beds demonstrate functionality of the sensors, with potential implications for monitoring of circadian cycles and mitigating risks for pressure-induced skin ulcers. (northwestern.edu)
  • Now let us see how the above factors control the distribution of blood flow in physiological situations. (washington.edu)
  • Some of the physiological factors that influence microvessels may be used as provocative tests. (termedia.pl)
  • Among other factors, friction impacts the nature of the vibrations generated by the relative movement of the fingertip skin against a probed object. (royalsocietypublishing.org)
  • They reported that the normal component of the grip force is influenced by three important factors: (i) the weight of the object, (ii) the friction between the object and the skin, and (iii) the safety margin set by the individual based on prior experience. (royalsocietypublishing.org)
  • However, a disease of pimples is the most common skin disease, which can occur even in any one such as women in the thirties to forties, or men who suffer from much stress. (freepatentsonline.com)
  • According to the journal, Maglie and Caproni diagnosed hematohidrosis, a rare disease marked by spontaneous discharge of "blood sweat" through intact skin. (cnn.com)
  • Disorders of thermoregulating function of skin circulation seem to be the cause of vibration disease. (cdc.gov)
  • Since under neutral conditions there is some steady sympathetic activity to the skin, reduction of the sympathetic effects allows vasodilation. (washington.edu)
  • We examined the effects of systemic hyperinsulinemia on skin microvascular function in eight healthy nondiabetic subjects. (jove.com)
  • In addition, the effects of locally administered insulin on skin blood flow were assessed in 10 healthy subjects. (jove.com)
  • Insulin iontophoresis was used to study the local effects of insulin on skin blood flow. (jove.com)
  • In their early studies Slagboom and her colleagues noted that the long-livers and their relatives are different from "ordinary" people on a number of physiological parameters. (baltictimes.com)
  • Application of Cutometer area parameters for the study of human skin fatigue. (nih.gov)
  • The aim of this study was to compare the informativeness of Cutometer standard R-parameters with new area parameters regarding the age-related changes in human skin fatigue. (nih.gov)
  • Skin mechanical parameters analyzed by Win-Cutometer MPA software were R3, R4 and R9 (R-parameters), and F2 and F3 (area parameters). (nih.gov)
  • The mechanical parameters R4 and F3 are most indicative of human skin fatigue. (nih.gov)
  • In this paper, we present evidence from our eyeblink setup that builds on and advances prior thinking regarding the physiological basis of the Rescorla-Wagner model. (pnas.org)
  • This allowed mould to flourish unseen and undetected, until it made its presence felt by outbreaks of eye, nose, throat and skin irritations and eventually the smell from the emitted chemicals. (theconversation.com)
  • These ultrasonic propagation properties were determined from measurements through the intercostal tissues, from the surface of the skin to the parietal pleura. (biomedsearch.com)
  • Analysis using immunogold localization revealed that pericytes synthesized and secreted LAMA5 in human skin. (nih.gov)
  • In turn this has allowed us to reinterpret human skin coloration and even fashion and military camouflage. (royalsocietypublishing.org)
  • As a result, tapes, Band-Aids, or other mechanical fixtures are required to establish a compact contact between wearable electronics and human skin, which can cause irritation and inconvenience during extended periods of use ( 27 , 28 ). (sciencemag.org)
  • A search for arteriovenous anastomoses in human skin using ultrasound Doppler. (exergen.com)
  • Stretching the skin beyond normal expansion invokes several mechanotransduction pathways which increase mitotic activity and promote collagen synthesis. (wikipedia.org)
  • In a method and apparatus for determining a physiological activity signal in a subject using various movement sensors that each transmit a temporal movement. (patents.com)
  • These physiological markers vary with emotional level, physical relaxation and mental activity. (indiana.edu)
  • To investigate the industrial potential of this cell line in detail, we tested extract for antioxidant and anti-inflammatory activity in the mouse monocyte/macrophage cell-line J774A.1 and in reconstructed skin tissue models. (frontiersin.org)
  • What better way to insure your baby gets his "daily dose" of skin-to-skin contact than through the pleasurable, invigorating and fun activity of baby/ infant massage ? (pregnancy-info.net)
  • Moderate usage of Diamond Dermabrasion, accompany with skin products that penetrate through top skin layer that reach the dermis level, helps to replenish natural nutrients, restore cell activity, and promote skin health. (sylvancompany.com)
  • In an effort to find a physiological explanation for the "rubber hand illusion," Duke researchers focused on brain activity in the somatosensory and motor cortices of monkeys. (newswise.com)
  • The superficial temporal artery demonstrates the necessary requirements for the skin thermometry method: it is easily accessible, contains no mucous membranes, and notably, it has no or very few arteriovenous anastomoses (AVA). (exergen.com)
  • This study provides a valuable overview of the transcriptome changes and gives insight into the genetic background that may be responsible for sunlight-dependent versus -independent anthocyanin biosynthesis in berry skin. (jove.com)
  • These data show that inhibiting the Akt pathway promotes autophagy and apoptosis in NMR skin fibroblasts. (pubmedcentralcanada.ca)
  • Furthermore, LY294002 or CQ treatment decreased caspase-3, p53, and HIF1-α levels, suggesting that serum starvation or H2O2 treatment increase autophagy and apoptosis in NMR skin fibroblasts by inhibiting the PI3K/Akt pathway. (pubmedcentralcanada.ca)
  • Changes in skin blood circulation in human subjects were examined by occlusive plethysmography, rheography, thermometry, sphygmography, and capillaroscopy. (cdc.gov)