Skeletal muscle strength. Medical search. Frequent questions

Sarcopenia is generally defined as the progressive loss of skeletal muscle mass and strength that occurs with aging ( 2 , 3 ). (frontiersin.org)
In a study published in the Journal of Cachexia Sarcopenia and Muscle , the research group coordinated by Dr. Daniel Metzger and Dr. Delphine Duteil characterized the effect of the absence of the androgen receptor in skeletal striated muscle fibers, leading to the development of muscle weakness and type 2 diabetes, and identified the underlying molecular mechanisms. (igbmc.fr)
As people age, their skeletal muscles begin to deteriorate, a process known as sarcopenia. (aarp.org)
The European Working Group on Sarcopenia in Older People and the Asian Working Group for Sarcopenia recommend SMI, as measured by the bioelectrical impedance analysis (BIA), and CC as methods for screening skeletal muscle mass. (medscape.com)
Sarcopenia, which is marked by a loss of skeletal muscle mass and strength, is associated with risks of adverse outcomes. (medscape.com)
Patients with heart failure have a high rate of sarcopenia, but assessing skeletal muscle mass in these patients is difficult because of the fluid retention they often have. (medscape.com)
Sarcopenia describes the loss of skeletal muscle mass, strength, and physical performance. (sharecare.com)
A study by an international team of researchers into sarcopenia -where muscles lose form and function with age - found that those with the condition reported higher numbers of falls in the last year and a higher prevalence of fractures. (southampton.ac.uk)
Age-related muscle loss (sarcopenia) is an important health problem associated with the aged population. (figshare.com)

Strength training stops the aging process in human skeletal muscle. (exercisesciencellc.com)
These results seem to suggest that strength training can counteract the age-related changes in function and morphology of the aging human skeletal muscle. (exercisesciencellc.com)

Simply writing, "R/O polymyositis" or "weakness", or worse, "muscle weakness" (we would not be concerned about weakness of character here, so using the term muscle weakness in this context seems oddly redundant) does not provide the pathologist with any useful clinical information and is a disservice to the patient. (medscape.com)
Its mutation in skeletal muscle myofibers induces metabolic disorders leading to type 2 diabetes, and structural defects leading to muscle weakness. (igbmc.fr)
4 Cross-sectional studies have typically demonstrated muscle weakness 5 and reduced endurance, 6 particularly of the lower limbs, in COPD compared with age-matched controls. (bmj.com)
In addition to weakness of the skeletal muscles, serious cardiac problems can occur in both diseases, which can be caused by a wide variety of mutations in the dystrophin gene. (mda.org)
Lead can accumulate in tissues and muscles, where it can lead to muscle weakness, fatigue, and eventually death from respiratory failure. (paradiseessentials2020.com)
This can lead to weakness and poor muscle coordination and memory, steroids 2 month results. (paradiseessentials2020.com)
The administration of intravenous dantrolene sodium to human volunteers is associated with loss of grip strength and weakness in the legs, as well as subjective CNS complaints (see also PRECAUTIONS, Information for Patients ). (nih.gov)
Muscle weakness is difficult to treat after a traumatic joint injury as it stems from a multifaceted interplay of neurological and morphological processes that disrupt the muscle's communication and regulation. (acsm.org)
To counteract this situation, clinicians must prioritize exercises that target the underlying causes of muscle weakness. (acsm.org)
Exploring alternative rehabilitation approaches that treat the underlying causes of muscle weakness is key to promoting more effective outcomes. (acsm.org)
Myasthenia gravis (MG) is a relatively rare acquired, autoimmune disorder caused by an antibody-mediated blockade of neuromuscular transmission resulting in skeletal muscle weakness and rapid muscle fatigue. (medscape.com)
Muscle weakness. (bvsalud.org)

The contraction of each muscle fiber bundle is controlled through the nerve impulses directed into the fiber bundle by a neuron, a type of electrical relay that is connected to the larger nervous system. (faqs.org)
When nerve impulses are communicated to the muscle, a complex series of electrochemical reactions convert the impulse into a muscle contraction. (faqs.org)
The actual muscle contraction generate within the muscle is fueled by the chemical reaction that occurs involving the compound adenosine triphosphate (ATP), which participates in a series of energy-producing reactions that involve creatine phosphate, present in the muscle cell, and gylcogen, transported to the cell through the blood as glucose. (faqs.org)
The myofibrils are composed of actin and myosin filaments called myofilaments, repeated in units called sarcomeres, which are the basic functional, contractile units of the muscle fiber necessary for muscle contraction. (wikipedia.org)
Contractile element simulates the behaviour of skeletal muscle when it is subjected to eccentric and concentric contraction. (techscience.com)
This research aims to estimate the stress induced in skeletal muscle in eccentric and concentric contraction with respect to the predefined strain. (techscience.com)
With the use of mathematical model for contraction of skeletal muscle for eccentric and concentric contraction, the stress induced in the skeletal muscle is estimated in this research. (techscience.com)
With the use of force-velocity of contraction of muscle, mathematical model is developed. (techscience.com)
This can be useful to understand the mechanical behaviour of skeletal muscles in eccentric and concentric contraction with clinical relevance. (techscience.com)
Tensiomyography measures the radial displacement of a muscle during an electrically evoked twitch contraction. (plos.org)
As such, a twitch provides information on muscle contractile properties and the functioning of the excitation-contraction coupling process. (plos.org)
Muscular fatigue causes a slowing of muscle contraction velocity, reversing as the muscle recovers from fatigue [ 21 - 24 ]. (plos.org)
Enhancement of skeletal muscle in aged rats following high-intensity stretch-shortening contraction training. (cdc.gov)
To address this issue, we utilized a rodent model that allowed training at maximal intensity in terms of muscle activation and tested the hypothesis that muscles of old rats adapt to stretch-shortening contraction (SSC) training, provided the training frequency is sufficiently low. (cdc.gov)
In skeletal muscle, dantrolene sodium dissociates the excitation-contraction coupling, probably by interfering with the release of Ca ++ from the sarcoplasmic reticulum. (nih.gov)
Skeletal muscles vary in their speeds of contraction. (msdmanuals.com)
It must be understood, however, that while isokinetic devices control the speed of the exertion, this does not assure a constant speed of muscle contraction. (cdc.gov)
Increasing the isokinetic speed of contraction will place increasing demands on Type II muscle fibers (fast twitch and fast oxida- tive glycolytic). (cdc.gov)

The functions of skeletal muscle include producing movement, maintaining body posture, controlling body temperature, and stabilizing joints. (wikipedia.org)

Angiotensin II helps control blood pressure and may also influence skeletal muscle function, although this role is not completely understood. (medlineplus.gov)

Examination of biopsies from the semitendinosus and biceps femoris muscles showed no alteration in water content or glycogen concentration with treatment. (bl.uk)
They conducted various muscle performance test and examined muscle biopsies. (exercisesciencellc.com)
Knowledge of the fundamentals of muscle biopsy pathology is useful to promote understanding of the pathogenesis of many types of neuromuscular disorders and assists the non-pathologist clinician to understand reports that he or she receives for the muscle biopsies from his or her patients. (medscape.com)
The article Skeletal Muscle - Structure and Histology provides a review of normal skeletal muscle histology and ultrastructure, including the histologic appearance of normal muscle with some of the various stains that are used for the processing of muscle biopsies. (medscape.com)
Most muscle biopsies exhibit a constellation of pathologic findings that must be synthesized to arrive at a diagnosis. (medscape.com)
We use translational approaches and regularly conduct focused intervention studies in humans, including skeletal muscle biopsies. (lu.se)
From the biopsies, muscle stem cells (satellite cells) are isolated and later used for preclinical measurements. (lu.se)
Our exercise studies include muscle biopsies and skeletal muscle satellite cells. (lu.se)

The speed with which the neurons communicate impulses to the muscle fiber group determine whether the fibers will be a fast-twitch fiber (useful in sports that require, power, strength, and reaction time), or a slow-twitch fiber (best suited to endurance sports). (faqs.org)
Muscles lose their strength, flexibility, and endurance over time, according to the Centers for Diseases Control and Prevention (CDC). (ibtimes.com)
The effect of strength and endurance exercise on skeletal muscle ultrastructure was investigated in 3 Thoroughbreds and 1 Heavy Hunter using various fixation procedures. (bl.uk)
In a previous study, we have demonstrated that Lactobacillus plantarum TWK10 (TWK10), a probiotic strain isolated from Taiwanese pickled cabbage, improved muscle strength, exercise endurance, and overall body composition in healthy humans. (frontiersin.org)
This longitudinal study was designed to document the extent of change in body composition (including muscle mass, fat mass and bone mineral composition) in older men and women, identify possible clinical conditions that accelerate these changes and examine the health impact of these changes on strength, endurance, disability and weight-related diseases of old age. (bmj.com)
These genes influence the fiber type that makes up muscles, and they have been linked to strength and endurance. (medlineplus.gov)
RAD-140 = Increase Strength RAD-140 = Increase Power RAD-140 = Decrease Endurance Slight increase in size Skeletal Muscle Mass and Strength Increase BodyFat Loss and Fat Loss: The bodyfat percentage and the amount have both been increased for this cycle, are sarms legal canada4. (paradiseessentials2020.com)
Uphill sprinting builds muscular endurance and muscle strength because the major muscles of the body have to work harder to propel your body up a hill. (livestrong.com)
The primary physical characteristics measured by these tests are the strength and endurance of the skeletal muscles and the speed or power of the legs. (britannica.com)
Muscular strength and endurance are also related to some aspects of health , as stated above. (britannica.com)
Treatment with high-frequency NMES did not improve muscle endurance or related EMG parameters. (wku.edu)
It is possible that NMES induced adaptations may be frequency-specific and that high-frequency NMES may not be efficacious when the goal is to improve skeletal muscle endurance. (wku.edu)
[ 12 ] STOMP researchers found that more patients in the atorvastatin group than in the placebo group developed muscle complaints, but there were no differences in muscle strength and endurance, aerobic performance, or physical activity levels after 6 months of treatment. (medscape.com)

Titin is a giant scaffold protein with multiple functions in striated muscle physiology. (frontiersin.org)
Muscles is an international, peer-reviewed , open access journal on muscle biology and physiology published quarterly online by MDPI. (mdpi.com)

The muscle will taper at its opposite end into a more slender connective tissue, the muscle tendon, to the connection with the bone, the point of insertion. (faqs.org)
The use of a muscle creatine kinase germline knockout of the gene encoding Ire1/Ern1 shifts the focus from traditional studies of tissue repair toward the regenerating myofibers. (elifesciences.org)
The findings shed new light on mechanisms of regeneration of healthy myofibers after severe tissue injury and suggest interplay between these fibers and muscle satellite cells though mechanisms remain to be elucidated. (elifesciences.org)
Skeletal muscle, the most abundant tissue of the body, has remarkable regenerative capacity mainly due to its resident muscle stem cells, also known as satellite cells. (elifesciences.org)
The muscle cells of skeletal muscles are much longer than in the other types of muscle tissue, and are often known as muscle fibers. (wikipedia.org)
The muscle tissue of a skeletal muscle is striated - having a striped appearance due to the arrangement of the sarcomeres. (wikipedia.org)
both of these types of muscle tissue are classified as involuntary, or, under the control of the autonomic nervous system. (wikipedia.org)
Each individual fiber, and each muscle is surrounded by a type of connective tissue layer of fascia. (wikipedia.org)
Apart from the contractile part of a muscle consisting of its fibers, a muscle contains a non-contractile part of dense fibrous connective tissue that makes up the tendon at each end. (wikipedia.org)
Connective tissue is present in all muscles as deep fascia. (wikipedia.org)
Basically, this means that the muscle tissue of the older strength trained subjects exhibited no aging when compared to younger subjects. (exercisesciencellc.com)
Skeletal muscles constitute a highly specialized tissue which features excellent plasticity in response to external stimuli, for example, training. (hindawi.com)
Fat Loss: The fat percentage and thickness of the muscle tissue will decrease as well, are sarms legal canada0. (paradiseessentials2020.com)
Fat Loss: The fat percentage and thickness of the muscle tissue will decrease as well. (paradiseessentials2020.com)
Results We investigated the alteration of genome-wide transcription in mouse skeletal muscle tissue (rectus femoris muscle) during aging using a high-throughput sequencing technique. (figshare.com)
Older adults who are obese with weight-related health problems should receive individual intervention to ensure weight reduction undertaken is beneficial and minimises loss of muscle tissue (slow weight loss with physical activity). (foodnavigator.com)
In the anesthetic-induced malignant hyperthermia syndrome, evidence points to an intrinsic abnormality of skeletal muscle tissue. (nih.gov)
Eccentric contractions (also known as lengthening contractions) offer a potent solution for muscle recovery by uniquely stimulating the nervous system and cellular signaling pathways that promote tissue health and growth. (acsm.org)

Abstract Background Aging leads to decreased skeletal muscle function in mammals and is associated with a progressive loss of muscle mass, quality and strength. (figshare.com)

A diet with blueberries might improve muscle growth and repair, finds a new study which revealed that the low-calorie dark blue colored berries might improve one's potential for preservation and recovery of skeletal muscle mass. (ibtimes.com)
Muscle mass can decrease about 3-5% every decade, especially after one turns 30. (ibtimes.com)
Muscle mass drops by ~3-8% per decade after age 30 and its declining rate is accelerated after age 60 ( 4 ). (frontiersin.org)
Muscle mass and strength in obstructive lung disease: a smoking gun? (bmj.com)
7 Skeletal muscle dysfunction seems to be clinically relevant in COPD, as loss of skeletal muscle mass and strength are associated with poor health status, 8 increased healthcare use 9 and even mortality, 2 10 independent of lung function parameters. (bmj.com)
In older people, as in COPD, sarcopaenia (loss of muscle mass and strength associated with ageing) is independently associated with disability and mortality. (bmj.com)
Other traits related to athleticism include the maximum amount of oxygen the body can deliver to its tissues (aerobic capacity), muscle mass, height, flexibility, coordination, intellectual ability, and personality. (medlineplus.gov)
Pilates, resistance training - anything that works your entire body - will preserve muscle and bone mass and protect you from injuries and falls. (aarp.org)
How Should Muscle Mass Be Measured in Heart Failure? (medscape.com)
In patients with heart failure , mid-upper arm circumference (MUAC) and arm muscle circumference (AMC) are more significantly associated with prognosis than guideline-recommended skeletal muscle mass index (SMI) or calf circumference (CC) measurements, research suggests. (medscape.com)
The investigators examined the association between skeletal muscle mass metrics, measured using bioelectrical impedance analysis (BIA), and anthropometric measures and prognosis in patients with heart failure. (medscape.com)
SMI was calculated using the BIA by dividing appendicular skeletal muscle mass by height squared. (medscape.com)
They excluded from their analysis 1013 patients who did not undergo a skeletal mass metrics evaluation and 48 who could not be followed up. (medscape.com)
Patients were separated into three groups on the basis of the sex-specific tertiles of skeletal muscle mass. (medscape.com)
Older people with an age-related loss of muscle mass and strength may be at greater risk of falling and bone fractures, according to new research led by the University of Southampton. (southampton.ac.uk)
The decline in muscle mass between the ages of 40 and 80 has been estimated to range from 30 to 60 per cent and is associated with disability, sickness and death. (southampton.ac.uk)
All of these definitions recognise that measuring muscle mass in isolation is inadequate and a measure of muscle function is also required, but there are differences in how function is assessed," says Dr Michael Clynes, lead author of the study from Southampton's Medical Research Council (MRC) Lifecourse Epidemiology Unit. (southampton.ac.uk)
This hormone plays a crucial role in bone growth during childhood and adolescence, as well as in maintaining muscle mass and strength throughout life. (proprofs.com)
It is well known that physical activity improves muscle mass, regardless of one's age, and has a positive effect on muscle strength [ 9 ]. (hindawi.com)
In women, a lower lean body mass results from a reduction of skeletal muscle mass which is visible between 30 and 50 years of age and intensifies in postmenopausal women [ 11 ]. (hindawi.com)
12 ], reactive oxygen and nitrogen species (RONS) may induce a reduction in muscle mass and strength due to changes in the functioning of the mitochondrial respiratory chain, with aging muscles becoming more susceptible to exercise-induced oxidative stress [ 13 ], as evidenced by increased lipid peroxidation, protein oxidation, and DNA damage. (hindawi.com)
In view of the above, it remains paramount to choose training loads that would ensure a balance between the production of RONS and maintaining proper muscle mass and good physical fitness [ 16 ]. (hindawi.com)
Improved body composition Skeletal Muscle Mass and Strength Increase, legal steroids no exercise. (paradiseessentials2020.com)
Skeletal Muscle Mass and Strength Increase. (paradiseessentials2020.com)
At termination of training, normalized muscle mass (i.e., muscle mass divided by tibia length) and muscle quality (isometric force divided by normalized muscle mass) were determined. (cdc.gov)
For young rats, normalized muscle mass increased by approximately 20% regardless of training frequency. (cdc.gov)
For old rats following 3 days per week training, normalized muscle mass was unaltered and muscle quality was 30% lower than young levels. (cdc.gov)
Following 2 days per week training at old age, normalized muscle mass increased by 17% and muscle quality was restored to young levels. (cdc.gov)
Lower risk older adults who are overweight are advised to avoid weight-loss diets in order to prevent loss of muscle mass. (foodnavigator.com)
Such movements recruit a large amount of muscle mass, which has a huge impact on hormone response. (bodybuilding.com)
However, there was no difference in muscle mass between the different dynapenic groups. (bvsalud.org)
Dynapenic women, diagnosed considering both cutoff points, had less total and segmental muscle mass compared to non-dynapenic women. (bvsalud.org)
During female aging, a muscle mass decrease occurs as well as greater accumulation and infiltration of fat, resulting from the endocrine changes that occur during the climacteric [1,2]. (bvsalud.org)

This is corroborated by biopsy findings of muscle fibre atrophy and muscle fibre shift from type I to type II fibres. (bmj.com)
Amongst the mice, when their muscles were examined four weeks after the injections, the team found that the stem cells had turned into new muscle and replaced up to 94% of the original muscle fibres. (thenakedscientists.com)
this is where many muscle cells join together to form what is effectively one giant cell containing many muscle fibres. (thenakedscientists.com)
A number of these loci contain genes implicated in structure and function of skeletal muscle fibres (ACTG1), neuronal maintenance and signal transduction (PEX14, TGFA, SYT1), or monogenic syndromes with involvement of psychomotor impairment (PEX14, LRPPRC and KANSL1). (lu.se)

Cardiac muscles are controlled through the function of the autonomic nervous system, the aspect of human function regulated by the hypothalamus region of the brain. (faqs.org)

The skeletal muscles are those tissues that are attached to the bones of the body beneath the skin. (faqs.org)
Your tendons, the tough tissues connecting muscles to bones, become less flexible because their water content drops by as much as 55 percent between childhood and late adulthood. (aarp.org)

As the muscles on examination appear to be constructed of varying lengths of strips, due to the manner in which the muscle fibers are situated, these muscles are also known as striated muscle. (faqs.org)
The muscle fibers that are the substance of each muscle are of similar construction throughout all skeletal muscles. (faqs.org)
In fine motor control muscles, such as the eyelid, the neuron may only control a group of 10 muscle fibers or fewer. (faqs.org)
In a large muscle such as the quadriceps or the gastrocnemius, each neuron may be connected to as many as 2,000 fibers. (faqs.org)
The fibers are made up of myofibrils, filaments that run the length of the muscle fiber. (faqs.org)
As the body rests, the muscle fibers attract cells known as myoblasts, which fuse with the existing fiber, causing the muscle fibers to become denser and stronger. (faqs.org)
Muscle size is not limitless, and the fibers will not attract unlimited numbers of myoblasts for repair, due to the presence of myostatin in the muscle cells. (faqs.org)
A skeletal muscle contains multiple fascicles - bundles of muscle fibers. (wikipedia.org)
Muscle fibers are formed from the fusion of developmental myoblasts in a process known as myogenesis resulting in long multinucleated cells. (wikipedia.org)
Muscle fibers also have multiple mitochondria to meet energy needs. (wikipedia.org)
Muscle fibers are in turn composed of myofibrils. (wikipedia.org)
Muscles are predominantly powered by the oxidation of fats and carbohydrates, but anaerobic chemical reactions are also used, particularly by fast twitch fibers. (wikipedia.org)
Skeletal muscles are substantially composed of multinucleated contractile muscle fibers (myocytes). (wikipedia.org)
To compensate for these metabolic alterations, amino acid catabolism is increased, generating ammonia and oxidative stress that impacts mitochondrial functions, and leads to necrosis of some muscle fibers. (igbmc.fr)
Skeletal muscles are made up of two types of muscle fibers: slow-twitch fibers and fast-twitch fibers. (medlineplus.gov)
these fibers are good for sprinting and other activities that require power or strength. (medlineplus.gov)
The ACTN3 gene provides instructions for making a protein called alpha (α)-actinin-3, which is predominantly found in fast-twitch muscle fibers. (medlineplus.gov)
These individuals have a complete absence of α-actinin-3, which appears to reduce the proportion of fast-twitch muscle fibers and increase the proportion of slow-twitch fibers in the body. (medlineplus.gov)
The 577RR genotype is associated with a high proportion of fast-twitch fibers and is seen more commonly in athletes who rely on strength or speed, such as short-distance runners. (medlineplus.gov)
The DD pattern is thought to be related to a higher proportion of fast-twitch muscle fibers and greater speed. (medlineplus.gov)
4,5] Moreover, the increased time under tension associated with moderate rep ranges is ideal for causing fatigue across the full spectrum of muscle fibers, maximizing increases in muscle size. (bodybuilding.com)
Skeletal muscles are bundles of contractile fibers that are organized in a regular pattern, so that under a microscope they appear as stripes (hence, they are also called striped or striated muscles). (msdmanuals.com)
Like skeletal muscle, cardiac muscle has a regular pattern of fibers that also appear as stripes under a microscope. (msdmanuals.com)

The operation of the nervous system and its relation to the skeletal muscular system is sometimes referred to as the neuromuscular system. (faqs.org)
Muscle biopsy often contributes significantly to the evaluation of patients with neuromuscular disease. (medscape.com)
Knowledge of the basic foundation of muscle biopsy also helps the clinician to understand in what situations a muscle biopsy would be expected to be helpful in assessment of the patient with neuromuscular disease and to be familiar with the types of information that it can provide. (medscape.com)
The article Muscle Biopsy and Clinical and Laboratory Features of Neuromuscular Disease provides information about the procedure of muscle biopsy and background about the general features of the clinical presentations of neuromuscular disorders. (medscape.com)
Neuromuscular electrical stimulation (NMES) is often used as a rehabilitative modality and evidence has suggested that high frequencies of NMES may elicit increases in muscle strength. (wku.edu)
The aim of this study was to determine the effect of a 4-week high-frequency NMES intervention on voluntary muscular fatigue and changes in neuromuscular activation patterns of the quadriceps during voluntary fatiguing muscle contractions in older adults. (wku.edu)
The autoimmune attack occurs when autoantibodies form against the nicotinic acetylcholine postsynaptic receptors at the neuromuscular junction of skeletal muscles (see the image below). (medscape.com)
[ 1 , 2 ] Although the chief target of the autoimmune attack in most cases is the skeletal muscle nicotinic acetylcholine receptor (nAChR), other antigenic targets that are components of the neuromuscular junction (NMJ) have also been implicated. (medscape.com)

These results indicate that TT association with SR-stacks enhances Orai1-dependent SOCE to optimize Ca 2+ dynamics and muscle contractile function during acute exercise. (elifesciences.org)
The rate of muscle displacement is increasingly reported to assess contractile properties. (plos.org)
A muscle twitch is the contractile response to a single electrochemical signal of the nervous system or artificial electrical stimulation of the muscle. (plos.org)
In isolated nerve-muscle preparation, dantrolene sodium has been shown to produce relaxation by affecting the contractile response of the muscle at a site beyond the myoneural junction. (nih.gov)
Few studies have examined the effects of statins on muscle contractile function and exercise performance, and even fewer studies have examined this in statin users with muscle complaints. (medscape.com)
The aim of the current study was to examine whether differences exist in aerobic exercise performance, muscle contractile function, and muscle mitochondrial oxidative capacity and content between long-term symptomatic and asymptomatic statin users, and control subjects who did not use a statin drug. (medscape.com)

This calls for dietary interventions and other strategies to improve muscle progenitor cell proliferation and lower oxidative stress that could aid muscle regeneration during aging. (ibtimes.com)
They then investigated how the serum would affect muscle progenitor cell function by calculating the cell number, capacity to manage oxidative stress, etc. (ibtimes.com)
Effects of roxburgh rose powder on oxidative stress in skeletal muscle of overtrained rats. (sciendo.com)
To determine whether differences exist in exercise performance, muscle function, and muscle mitochondrial oxidative capacity and content between symptomatic and asymptomatic statin users, and control subjects. (medscape.com)
Statin use attenuated substrate use during maximal exercise performance, induced muscle fatigue during repeated muscle contractions, and decreased muscle mitochondrial oxidative capacity. (medscape.com)
This suggests disturbances in mitochondrial oxidative capacity occur with statin use even in patients without statin-induced muscle complaints. (medscape.com)
[ 4-6 ] Although the mechanisms are poorly understood, statins have been shown to reduce muscle mitochondrial oxidative capacity and content in humans [ 7-10 ] and impair exercise-mediated mitochondrial adaptations in skeletal muscle. (medscape.com)

Skeletal muscle comprises about 35% of the body of humans by weight. (wikipedia.org)
Currently, research on dietary interventions to support skeletal muscle regeneration in humans is limited. (ibtimes.com)
In humans this disease is characterised by the progressive destruction of muscle leaving sufferers weakened and eventually almost immobile. (thenakedscientists.com)

Protein-interactions e.g., with muscle ankyrin repeat proteins or muscle LIM-protein link titin to hypertrophic signaling and via p62 and Muscle Ring Finger proteins to mechanisms that control protein quality control. (frontiersin.org)
Function, morphology and protein expression of ageing skeletal muscle: a cross-sectional study of elderly men with different training backgrounds. (exercisesciencellc.com)
To explore whether they could be used to repair diseased muscles, the satellite cells were labelled with a glowing green protein and injected into the muscles of mice carrying a mutation in their dystrophin genes, giving them the rodent equivalent of muscular dystropy. (thenakedscientists.com)
An absence of the muscle protein dystrophin is the underlying cause of Duchenne muscular dystrophy (DMD) , while a partial lack of dystrophin is the cause of Becker muscular dystrophy (BMD) . (mda.org)
When post-exercise hyperinsulinaemia is supported by hyperaminoacidaemia induced by protein hydrolysate and leucine ingestion, net protein deposition in muscle should occur. (bmj.com)
Appropriate resistance exercise leads to significant skeletal muscle hypertrophy, which can occur through an increase in protein synthesis, a decrease in protein degradation, or both. (bmj.com)
Obviously, the hormonal milieu of the muscle also has a major impact on protein synthesis. (bmj.com)
It is now apparent that both increased insulin and increased availability of amino acids are important for maximizing muscle protein anabolism. (bmj.com)
2 On the other hand, if amino acid concentrations are maintained at normal or higher concentrations, net protein deposition in muscle will occur because of stimulation of synthesis and possibly because of a simultaneous decrease in breakdown. (bmj.com)
This is in line with the recent data obtained by Borsheim et al , 4 who showed that protein balance over the muscle remains negative after resistance exercise when only carbohydrate (CHO) is ingested. (bmj.com)
In sharp contrast, amino acid ingestion alone significantly increases muscle protein anabolism after resistance exercise. (bmj.com)
5 However, consumption of both amino acids and CHO results in much greater effects on muscle protein anabolism, 6 suggesting an interactive effect between insulin, amino acid availability, and resistance exercise. (bmj.com)
Also, it is well established that the stimulatory effect of amino acids on muscle protein synthesis is greater after exercise than at rest. (bmj.com)
Effects of high housing and low training on the expression of hypoxiainducible factor-1α and vascular endothelial growth factor protein in skeletal muscle of rats. (sciendo.com)
For example, whey protein isolate can improve your ability to make muscle, and post-workout supplements can help you push through recovery. (breakingmuscle.com)
Bodybuilders who practice energy restriction in addition to resistance training and high-intensity exercises have a high protein threshold to meet for muscle gain. (breakingmuscle.com)
Research has proven that supplementing with at least 15 grams of whey protein before and after strength training leads to increased muscle creation. (breakingmuscle.com)
The report said the over 65s need 'high quality proteins to stimulate muscle protein' and recommended that healthy older adults eat a more protein-dense diet consisting of foods such as meat poultry, fish, dairy and eggs. (foodnavigator.com)

0.001), indicating that MTR may be more sensitive to muscle damaged by denervation than conventional MRI. (bmj.com)

Differential splicing of the titin gene results in numerous species- and muscle-specific titin isoforms. (frontiersin.org)
In contrast to swimmers and runners, the elderly strength trained subjects had maximal isometric torques, speed of movements, cross-sectional areas, specific tensions and a content of myosin and tropomyosin isoforms in both muscle studied IDENTICAL to those of young controls. (exercisesciencellc.com)
Specifically, genes associated with energy metabolism, cell proliferation, muscle myosin isoforms, as well as immune functions were found to be altered. (figshare.com)

The striated skeletal muscle is a key organ of the energetic metabolism. (igbmc.fr)
It controls many genes involved in muscle structure and strength, as well as in energy metabolism. (igbmc.fr)
Aging effect on skeletal muscle lipid metabolism-related regulation factor. (sciendo.com)
Evidence-based research teaches us that bodybuilders have a lowered risk of heart-related issues, burn calories more effectively, have a high muscle-to-fat ratio and increased strength threshold, and effectively manage their metabolism. (breakingmuscle.com)
Our research interest is to understand how genetic variation influences skeletal muscle function and whole-body metabolism. (lu.se)

Almost all joints in the body are comprised of muscles that operate in pairs: one muscle acts as an extensor, to extend or straighten the joint, and the other muscle in the pair acts as a flexor, to facilitate the bending of the joint. (faqs.org)
Skeletal muscles are responsible for the relative motion of the bones at the joints and provide the required strength. (techscience.com)
Skeletal muscles, which are responsible for posture and movement, are attached to bones and arranged in opposing groups around joints. (msdmanuals.com)
Most isokinetic devices available on the market focus on quantifying strength about isolated joints or body segments, for example, trunk extension and flex- ion (see Figure 7). (cdc.gov)
For this rea- son, machines that measure isokinetic strengths of isolated joints or body seg- ments should not be used as a method of evaluating worker capabilities related to job demands in most instances. (cdc.gov)

Here is an example to illustrate the lack of specificity of histopathologic findings and the importance of clinical information for interpretation of a muscle biopsy: A biopsy might exhibit myofibers that contain clear vacuoles on hematoxylin and eosin (H&E) sections. (medscape.com)
Structural differences between healthy muscle (left) and muscle in which the androgen receptor is not expressed in the myofibers (right). (igbmc.fr)
Its ablation in skeletal muscle myofibers causes a decrease in glycolytic activity and fatty acid oxidation in muscles, leading to the premature development of type 2 diabetes specifically in male mice. (igbmc.fr)

Exercise promotes the formation of intracellular junctions in skeletal muscle between stacks of sarcoplasmic reticulum (SR) cisternae and extensions of transverse-tubules (TT) that increase co-localization of proteins required for store-operated Ca 2+ entry (SOCE). (elifesciences.org)
Function and mechanism of sarcoplasmic reticulum/endoplasmic reticulum calcium ATPase in skeletal muscle. (sciendo.com)

Depending on their type, physical exercises induce a number of phenotypic and physiological changes such as mitochondrial biogenesis, muscle fiber transformation, angiogenesis, improvement of insulin sensitivity, and cytoprotection [ 10 ]. (hindawi.com)
Also, muscle biopsy specimens were not obtained in the STOMP trial to investigate whether changes in mitochondrial content and/or function occur during statin treatment andwhether they relate to muscle complaints and exercise performance. (medscape.com)

The function and morphology of knee extension/m. vastus lateralis and elbow flexion/m. biceps brachii were studied in young (28 +/- 0.1 years, n = 7) and elderly (68 +/- 0.5 years, n = 8) sedentary subjects and in elderly swimmers (69 +/- 1.9 years, n = 6), runners (70 +/- 0.7 years, n = 5) and strength-trained subjects (68 +/- 0.8 years, n = 7). (exercisesciencellc.com)
These results suggest that the adaptations of tendon properties and muscle morphology to resistance training are slower than those of muscle function and inversely that the adaptations of former to detraining are faster than those of latter. (nih.gov)
Effects of blood flow restriction training on skeletal muscle morphology and strength in elderly. (sciendo.com)

Skeletal muscles (commonly referred to as muscles) are organs of the vertebrate muscular system and typically are attached by tendons to bones of a skeleton. (wikipedia.org)
The tendons attach the muscles to bones to give skeletal movement. (wikipedia.org)
The length of a muscle includes the tendons. (wikipedia.org)

Cardiac muscle (heart muscle) is used only to power the contractions of the heart. (faqs.org)
Acute rhabdomyolysis with hyperkalemia followed by ventricular dysrhythmias, cardiac arrest, and death has occurred after use in apparently healthy pediatric patients who were subsequently found to have undiagnosed skeletal muscle myopathy. (nih.gov)
The second study is to compare two cardiac drugs, losartan (Cozaar) and lisinopril (Prinivil, Zestril), for their effects on cardiac and skeletal muscle in DMD. (mda.org)
Cardiac muscle forms the heart and is not part of the musculoskeletal system. (msdmanuals.com)
However, cardiac muscle contracts and relaxes rhythmically without a person's awareness. (msdmanuals.com)

The reality check in your 70s: Keeping muscles and bones healthy is a top priority. (aarp.org)
Growth hormone primarily targets bones and skeletal muscles. (proprofs.com)

We demonstrate that transgenic AAVR overexpression greatly increases the efficiency of transduction of many diverse cell types, including muscle stem cells, which are normally refractory to AAV transduction. (nature.com)
Working with mice and writing in the journal Cell, Harvard researcher Amy Wagers and here colleagues used chemical markers to identify a sub-population of adult muscle cells called satellite cells, some of which behave like muscle stem cells. (thenakedscientists.com)
As a result, when the stem cells merge with the syncitium, they bring with them a healthy copy of the dystrophin gene, which enables the rest of the muscle to function much better. (thenakedscientists.com)
Taken together, these data indicate that skeletal muscle precursors [the satellite cells] act as renewable, transplantable stem cells for adult skeletal muscle," says Wagers. (thenakedscientists.com)

Effects of treadmill exercise on skeletal muscle apoptosis and VEGFB and its receptor expression in rats with heart failure induced by abdominal aortic constriction. (sciendo.com)

The purpose of this study was to investigate the time course of changes in mechanical and morphological properties of muscle and tendon during isometric training and detraining. (nih.gov)
Tensiomyography (TMG) measures the radial displacement of a muscle belly during an electrically stimulated isometric twitch response. (plos.org)
Physical capacity measurements included five-time chair-stand time, 6-minute walking distance, and maximal isometric knee-extension strength. (humankinetics.com)
Maximal incremental cycling tests, involuntary electrically stimulated isometric quadriceps-muscle contractions, and biopsy of vastus lateralis muscle. (medscape.com)
It is clear that isometric strength testing cannot substitute for dynamic strength assessment when examining highly dynamic occupational job demands. (cdc.gov)
As most industrial work tasks contain a significant dynamic component, analysis of isokinetic strength capabilities appears to offer some advantage to isometric testing in this regard. (cdc.gov)

Performance of repetitive tasks induces decreased grip strength and increased fibrogenic proteins in skeletal muscle: role of force and inflammation. (cdc.gov)

the muscle repairs itself during rest between resistance training sessions. (faqs.org)
Variable resistance training (VRT) methods improve the rate of force development (RFD), coordination between antagonist and synergist muscles, the recruitment of motor units, and reduce the drop in force produced in the sticking region. (researchgate.net)
Thus, consumption of post-exercise recovery drinks containing these nutrients in conjunction with appropriate resistance training may lead to increased skeletal muscle hypertrophy and strength. (bmj.com)
Although stimulation-that is, resistance exercise-is important for muscle hypertrophy, nutrient availability appears to be a critical factor regulating the degree of hypertrophy. (bmj.com)
If one desires to develop strength, resistance or strengthening exercises must be employed. (britannica.com)
High-intensity resistance exercise, in particular, also maximizes skeletal muscle size and strength-outcomes crucial at advanced age. (cdc.gov)
Similarly, as the muscle reaches its optimal mechanical advantage, the resistance of the machine increases proportionally. (cdc.gov)
Among older diabetic adults, resistance training can improve muscle strength and glycemic control (7,8). (cdc.gov)

Myofiber-specific ablation of IRE1α or XBP1 in mice diminishes skeletal muscle regeneration that is accompanied with reduced number of satellite cells. (elifesciences.org)
Myofiber-specific ablation of IRE1α dampens Notch signaling and canonical NF-κB pathway in skeletal muscle of adult mice. (elifesciences.org)
Finally, targeted ablation of IRE1α also reduces Notch signaling, abundance of satellite cells, and skeletal muscle regeneration in the mdx mice, a model of Duchenne muscular dystrophy. (elifesciences.org)

Although the team are not suggesting that this is the cure for muscular dystrophy at this stage, what they have shown is that there are cells that can be used to effectively repair adult muscle, which might be useful for a host of different diseases. (thenakedscientists.com)

The intervention included supervised and home-based strength, balance, and walking exercises. (humankinetics.com)
However, little is known regarding the effects of a high-frequency NMES intervention on voluntary skeletal muscle fatigue. (wku.edu)

In the present study, we demonstrate that IRE1α (also known as ERN1) and its downstream target, XBP1, are activated in skeletal muscle of mice upon injury. (elifesciences.org)
We found that TWK10 not only enhanced muscle strength in young mice, but also prevented the aging-related loss of muscle strength in aged mice, which was accompanied by elevated muscle glycogen levels. (frontiersin.org)
The functional benefits of exercise on SOCE, constitutive Ca 2+ entry and muscle force production were lost in mice with muscle-specific loss of Orai1 function. (elifesciences.org)
Analysis revealed significant transcriptional changes between skeletal muscles of mice at 3 (young group) and 24 (old group) months of age. (figshare.com)

Hand grip strength is a widely used proxy of muscular fitness, a marker of frailty, and predictor of a range of morbidities and all-cause mortality. (lu.se)
Mendelian randomization analyses are consistent with a causal effect of higher genetically predicted grip strength on lower fracture risk. (lu.se)
In conclusion, our findings provide new biological insight into the mechanistic underpinnings of grip strength and the causal role of muscular strength in age-related morbidities and mortality. (lu.se)

Dm provides information on skeletal muscle stiffness, morphological and structural changes [ 2 - 4 ]. (plos.org)

Our research, along with others, has demonstrated the power of an exercise prescription emphasizing eccentric contractions to effectively enhance neural drive and cellular signaling, which are responsive to muscle stretch and repetitive lengthening. (acsm.org)
To this point, we and others have found that training with eccentric contractions improves the magnitude and firing rate of alpha-motoneurons, resulting in greater strength recovery and knee movement profiles in those with a significant history of joint injury relative to concentrically treated patients. (acsm.org)
Through our review paper, we aim to stimulate dialogue and reflection regarding current practices and the safe use of eccentric contractions to enhance muscle recovery. (acsm.org)

Skeletal muscle continuum constitutive model at variable strain rate. (sciendo.com)

Considerable research on skeletal muscle is focused on the muscle fiber cells, the myocytes, as discussed in detail in the first sections, below. (wikipedia.org)

The remainder of this article addresses the key clinical characteristics and pathologic findings on muscle biopsy of selected examples of disorders from 4 different categories of muscle disease: immune-mediated (inflammatory) myopathies, muscular dystrophies, metabolic myopathies, and congenital myopathies. (medscape.com)

Skeletal muscle is a distinct type of specialized muscles found within the body. (faqs.org)
Smooth muscles are located within every hollow organ in the body, with the exception of the heart. (faqs.org)
All skeletal muscles are positioned relative to the bone in a similar fashion no matter where in the body they may be positioned, irrespective of the muscle function. (faqs.org)
Myostatin is the hormone produced by the body that regulates muscle size, a natural limit on how large muscles can grow. (faqs.org)
Front and back views of the major skeletal muscles of the human body There are more than 600 skeletal muscles in the human body, making up around 40% of body weight in healthy young adults. (wikipedia.org)
Most muscles occur in bilaterally-placed pairs to serve both sides of the body. (wikipedia.org)
The slope of a hill targets the glutes, hamstrings, quadriceps, calves, core and upper body and, similar to weight training, allows you to build more muscle. (livestrong.com)
For this reason, a split routine, where you perform multiple exercises for a specific muscle group, may be more beneficial for a hypertrophic response compared to full-body routines. (bodybuilding.com)
9] Split routines allow you to focus on one or two muscle groups per workout, maintaining total weekly volume, but with fewer working sets per session compared to a full-body workout. (bodybuilding.com)
Skeletal muscle is what most people think of as muscle, the type that can be contracted to move the various parts of the body. (msdmanuals.com)
Several investigators have used dynamic isokinetic lifting devices designed to measure whole-body lifting strength. (cdc.gov)
Figure 8 --An isokinetic whole-body strength measurement system. (cdc.gov)
the females in the normal maturational state had higher skeletal age, body weight, body height, explosive upper limb strength and oestradiol levels. (bvsalud.org)

Age- and load-dependent variations in apoptotic quantification and localization with skeletal muscle adaptation and maladaptation. (cdc.gov)

These results imply that, appropriately scheduled high-intensity SSC training at old age is capable of restoring muscle to a younger phenotype in terms of lipid peroxidation levels and muscle quality. (cdc.gov)

intrinsic and extrinsic muscles are subdivisions of muscle groups in the hand, foot, tongue, and extraocular muscles of the eye. (wikipedia.org)

to provide skeletal muscle relaxation during surgery or mechanical ventilation. (nih.gov)
Authors are further working to develop the mathematical model with torsion force with proper activation function of muscle and experimentation for extraction of the anisotropic mechanical properties of skeletal muscle. (techscience.com)
It also engages essential stretch-sensing properties of the muscle, which convert mechanical stress into responses that promote muscle growth. (acsm.org)
At the extremes of the range of motion of a joint, the muscle has the least mechanical advantage, and the resis- tance offered by the machine is correspondingly lower. (cdc.gov)

However, the mechanisms of muscle regeneration are not yet fully understood. (elifesciences.org)
Her research focuses on elucidating the mechanisms that regulate skeletal muscle strength, activation, and structure after traumatic joint injury to establish interventions that optimize muscle recovery. (acsm.org)

Under different physiological conditions, subsets of 654 different proteins as well as lipids, amino acids, metabolites and small RNAs are found in the secretome of skeletal muscles. (wikipedia.org)

NMES and Skeletal Muscle Fatigue" by Monica A. Mendoza, Kyndall P. Ramirez et al. (wku.edu)
Surface electromyography (sEMG) of the vastus lateralis (VL) and vastus medialis (VM) muscles were recorded during the fatigue task to examine changes in muscle activation. (wku.edu)

At beginning and on every 1 month of training and detraining periods, muscle strength, neural activation level, muscle and tendon cross-sectional areas (CSA), and tendon stiffness were measured. (nih.gov)
During detraining period, muscle strength and neural activation level did not change, although muscle CSA and tendon stiffness decreased to pre-training level at 1 and 2 months of detraining, respectively. (nih.gov)

However, such training is capable of inducing muscle maladaptation when misapplied at old age. (cdc.gov)

The consequences associated with the deterioration of skeletal muscle are a loss of mobility, decreased quality of life, and ultimately, loss of independence. (ibtimes.com)
Muscle loss is closely correlated with an increased risk of falls and fractures, physical disability, poor quality of life, and death. (frontiersin.org)
They include: Drowsiness Nausea Muscle pain Frequent vomiting High blood pressure Loss of bowel and kidney function Headaches Possible increased risk of cancer Toxins (especially lead and iron) can be found in Ostarine. (paradiseessentials2020.com)
Loss of the functional skin such as muscle, nerves, blood vessels and barrier after thermal injury results in in- bone despite the absence of a major cutane- creased susceptibility to infection, which is ous injury. (who.int)
Older adults with diabetes are more likely than those without the disease to have less muscle strength, poorer muscle quality, and accelerated muscle loss (4). (cdc.gov)

this will not present instruction on the subtleties of advanced muscle biopsy diagnosis. (medscape.com)
This article first presents and contrasts neurogenic and general myopathic features on muscle biopsy. (medscape.com)
Interpretation of a muscle biopsy can be a challenging task. (medscape.com)

Interfering with angiotensin causes blood vessels to dilate, decreasing workload for the heart and possibly increasing blood flow to muscles. (mda.org)

We evaluated the maturity achieved by a predictive equation of skeletal age, physical capabilities (explosive power of upper and lower limbs, velocity of upper limbs and agility) and hormonal markers (testosterone and oestradiol) via chemiluminescence. (bvsalud.org)

The reactions occur very quickly, and a muscle can be restored to its rest position after the activity generated by an impulse in approximately one millisecond. (faqs.org)

This preliminary study of muscle progenitor cell function paves the way for future studies to develop clinical interventions," EurekAlert quoted the study's lead author Anna Thalacker-Mercer, Ph.D. (ibtimes.com)
Some are involved in the function of skeletal muscles, while others play roles in the production of energy for cells, communication between nerve cells, or other cellular processes. (medlineplus.gov)
Thus, SOCE plays an important role in both normal muscle development/function and muscle disease. (elifesciences.org)
Vitamin D is necessary for maintaining the structural integrity and function of muscles [ 14 ]. (hindawi.com)
For example, the Effect of Statins on Skeletal Muscle Function and Performance (STOMP) trial is, to our knowledge, the only randomized, double-blind clinical trial that has examined aerobic exercise performance and muscle strength before and after treatmentwith placebo or high-dose atorvastatin. (medscape.com)
Only statin-naive individualswere studied in STOMP, however, so the absence of deleterious changes in muscle function and performance may not apply to symptomatic statin users. (medscape.com)
It is our hope that this research will lead to new understanding of skeletal muscle function with implications primarily for human health, but also provide answers to fundamental evolutionary questions. (lu.se)

The investigators hope to recruit 800 participants who have a diagnosis of DMD or BMD with a documented mutation of the dystrophin gene, and who can cooperate with Doppler echocardiogram testing and skeletal-muscle testing. (mda.org)

However, the beneficial effects of long-term VRT on maximal strength both in athletes and untrained individuals have been much disputed. (researchgate.net)
Long-term VRT training using chains or elastic bands attached to the barbell emerged as an effective evidence-based method of improving maximal strength both in athletes with different sports backgrounds and untrained subjects. (researchgate.net)
More specifically, some exercises are better than others, some loads are more optimal for building maximal size , and certain training styles and training volumes can put you on the road to muscle growth. (bodybuilding.com)
Strength Test as a Predictor for Maximal and Acceptable Lifting. (cdc.gov)

In our projects we combine physiological measurements like VO2MAX, muscular strength and glucose tolerance with preclinical, e.g. (lu.se)

After strength exercise disruption was noted in all samples. (bl.uk)
3 This limitation in exercise and functional capacity has led to a particular focus upon the skeletal muscle compartment. (bmj.com)
Certainly, a surprisingly high proportion of patients with COPD terminate exercise complaining of muscle effort. (bmj.com)
Here, we report that SOCE, peak Ca 2+ transient amplitude and muscle force production during repetitive stimulation are increased after exercise in parallel with the time course of TT association with SR-stacks. (elifesciences.org)
While 37 percent of adults age 65-plus worry about their weight at least some of the time, a healthier approach is to focus on pampering and strengthening your muscles with a nutritious diet and a comfortable amount of regular exercise. (aarp.org)
The program framework is designed to prepare students to become certified by the American College of Sports Medicine as a Certified Exercise Physiologist (ACSM EP) or by the National Strength and Conditioning Association as a Certified Strength and Conditioning Specialist (NSCA CSCS). (mnsu.edu)
Training intensity is arguably the most important exercise variable for stimulating muscle growth. (bodybuilding.com)
To improve this situation, rehabilitation specialists need to think beyond conventional forms of exercise prescription, as it is clear that the current treatment approaches fail to adequately restore muscle strength. (acsm.org)
In our review paper , published in Exercise and Sport Sciences Reviews (ESSR) , we propose a novel framework for an exercise prescription in muscle recovery that is often overlooked. (acsm.org)
Eccentric exercise achieves this by maintaining muscle communication through neural pathways less affected by the initial injury. (acsm.org)
The size and strength of skeletal muscles are maintained or increased by regular exercise. (msdmanuals.com)
[ 2 ] However, 7% to 29% of patients are reported to develop muscle complaints while receiving statin treatment, [ 3 ] and these complaints may be exacerbated by exercise. (medscape.com)
This type of exercise allows the muscle to contract at its maximum capability at all points throughout the range of motion. (cdc.gov)

Anatomy41

Organisms5

Diseases13

Chemicals and Drugs17

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Psychiatry and Psychology1

Phenomena and Processes44

Anthropology, Education, Sociology and Social Phenomena9

Information Science1

Health Care2

Sarcopenia9

Human skeletal muscle2

Weakness12

Contraction18

Functions of skeletal muscle1

Influence skeletal muscle1

Biopsies8

Endurance13

Physiology2

Tissue18

Abstract1

Mass33

Fibres4

Autonomic nervou1

Tissues2

Fibers23

Neuromuscular8

Contractile6

Oxidative7

Humans3

Protein18

Denervation1

Isoforms3

Metabolism5

Joints5

Myofibers3

Sarcoplasmic reticulum2

Mitochondrial2

Morphology3

Tendons3

Cardiac5

Bones2

Stem cells4

Treadmill exercise1

Isometric6

Induces1

Resistance8

Ablation3

Diseases1

Intervention2

Mice4

Grip strength3

Morphological1

Contractions3

Constitutive1

Fiber1

Myopathies1

Body13

Localization1

Lipid1

Intrinsic1

Mechanical4

Mechanisms2

Proteins1

Fatigue2

Stiffness2

Maladaptation1

Loss5

Biopsy3

Blood vessels1

Hormonal1

Occur1

Function7

Mutation1

Maximal4

Muscular Strength1

Exercise13