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AdenocarcinomaMucinsJaagsiekte sheep retrovirusPulmonary Adenomatosis, OvineMucin 5ACLung NeoplasmsAdenocarcinoma, Bronchiolo-AlveolarMesotheliomaErigeronRespiratory MucosaMucin-2Keratin-7Carcinoma, MucoepidermoidAdenocarcinoma, MucinousMucin-5BPulmonary Surfactant-Associated Protein AGoblet CellsGastric MucinsReceptor, Epidermal Growth FactorImmunohistochemistryProteolipidsPseudomyxoma PeritoneiLungTumor Markers, BiologicalVanadium CompoundsSolitary Pulmonary NoduleEpithelial CellsPulmonary SurfactantsPneumonectomyMetaplasiaPancreatic NeoplasmsEsophageal NeoplasmsKeratinsImmunoenzyme TechniquesMucusAdenocarcinoma, PapillaryTransforming Growth Factor alphaBarrett EsophagusCarcinoma, Pancreatic DuctalPrognosisLeukocyte ElastaseStomach NeoplasmsSheepGene Expression Regulation, NeoplasticTumor Cells, CulturedTomography, X-Ray ComputedCell Line, TumorCardiaNuclear ProteinsColonic NeoplasmsMutationInterleukin-13RNA, MessengerTranscription FactorsIn Situ HybridizationSensitivity and SpecificityUp-RegulationEsophagogastric JunctionNeoplasm StagingCarcinoma in SituIn Situ Hybridization, FluorescenceMucin-1Carcinoma, Squamous CellPrecancerous ConditionsEndometrial NeoplasmsMucin-4Neoplasms, Multiple PrimaryIntestinal NeoplasmsSignal TransductionGene Expression RegulationPhosphorylationProstatic NeoplasmsCells, CulturedNeoplasm InvasivenessCarcinoma, Signet Ring CellMammary Neoplasms, ExperimentalDuodenal NeoplasmsCarcinoma, EndometrioidCecal NeoplasmsAdenocarcinoma, Clear CellColorectal NeoplasmsRectal NeoplasmsNeoplasm ProteinsAdenomaTissue Array AnalysisGenes, rasAmpulla of VaterNeoplasm TransplantationCommon Bile Duct NeoplasmsKeratin-20Neoplasm MetastasisDNA, NeoplasmMucin-6Antineoplastic AgentsIleal NeoplasmsSurvival RateReverse Transcriptase Polymerase Chain ReactionPancreaticoduodenectomyLymphatic MetastasisAntigens, Neoplasm

TumorsCarcinomaPoorly-differentiatedIdiopathicPapillaryAirwayDiffuseAbundantCancersLung cancerNeoplasmsCommonlySubtypesMucusMalignantRefersSignsSquamous cell carcSignet ring cellMinimally invasive adenocarcinomaMucinous adenocarcinomaEndocervical AdenocarcinomaHistologicAlveolarParaneoplastic syndromesPrognosisHistologicalNoduleSolitaryPeptideLung cancersBladderCitationClassificationChronicInfectionsDemonstratePatientsAcinarRareFeaturesPrimaryCasesFamilyFull

Tumors4

• [ 1 ] This article focuses on cutaneous paraneoplastic syndromes caused by solid tumors. (medscape.com)
• Triphasic pancreatic-protocol computed tomography is the best initial diagnostic test for pancreatic cancer, and on this modality these tumors appear as a hypodense solid mass. (coek.info)
• A small proportion of these tumors show large ducts lined by neoplastic cells, the so-called large-duct variant of adenocarcinoma. (coek.info)
• He is also involved in other areas of clinical oncology as well as in translational research on immunology and biomarkers on solid tumors. (unav.edu)

Carcinoma7

• The most common paraneoplastic syndromes associated with adenocarcinoma of the lung are described below: Hypercalcemia of malignancy is more common in squamous cell carcinoma of the lung, but can occur in adenocarcinoma as well. (wikipedia.org)
• 2. Signet-ring cell carcinoma, scirrhous carcinoma, solid carcinoma (poorly-differentiated). (poznayka.org)
• Microscopically, early gastric carcinoma is a typical glandular adenocarcinoma, usually well-differentiated. (poznayka.org)
• carcinoma in situ in the stomach (a state of severe cellular atypia or dysplasia, without invasion across the basement membrane of the glands). (poznayka.org)
• Microscopically, it may be an adenocarcinoma or signet-ring cell carcinoma, extensively infiltrating the stomach wall, but due to marked desmoplasia cancer cells may be difficult to find. (poznayka.org)
• carcinoma contains abundant pools of mucin in which are seen a small number of tumor cells, sometimes having signet-ring appearance. (poznayka.org)
• In spite of their aggressive biologic behavior, some ductal adenocarcinomas show bland nuclear features, making the distinction of benign lesion from an invasive carcinoma difficult, particularly on small biopsy specimens (Fig. 1). (coek.info)

Poorly-differentiated1

• Macroscopically, ulcerative carcinomas are poorly-differentiated adenocarcinomas, which invade deeply into the stomach wall. (poznayka.org)

Idiopathic1

• Idiopathic pulmonary hemosiderosis. (radiopaedia.org)

Papillary2

• 1. Adenocarcinoma: papillary, mucoid, trabecular (well-differentiated). (poznayka.org)
• Microscopically, fungating or polypoid carcinomas are well-differentiated adenocarcinomas, commonly papillary type. (poznayka.org)

Airway5

• Despite progress in animal studies, the genes and their expression pattern involved in mucus production and secretion in human airway epithelium are not well understood. (biomedcentral.com)
• We hypothesized that comparison of the transcriptomes of the small airway epithelium of individuals that express high vs low levels of MUC5AC, the major macromolecular component of airway mucus, could be used as a probe to identify the genes related to human small airway mucus production/secretion. (biomedcentral.com)
• The identification of the genes associated with increased airway mucin production in humans should be useful in understanding the pathogenesis of airway mucus hypersecretion and identifying therapeutic targets. (biomedcentral.com)
• Little is known about the gene networks associated with the synthesis and secretion of mucins in the human small airway epithelium. (biomedcentral.com)
• The process of mucus production and secretion is central to the normal defense of the lung, with mucus an important component of the airway mucociliary escalator that continuously cleanses the lung of inhaled particulates, pathogens and xenobiotics [ 1 ]. (biomedcentral.com)

Diffuse1

• Diffuse pulmonary nodules. (radiopaedia.org)

Abundant1

• Histologically, most ductal adenocarcinomas are composed of glandlike structures embedded in an abundant desmoplastic stroma. (coek.info)

Cancers1

• Like many lung cancers, adenocarcinoma of the lung is often advanced by the time of diagnosis. (wikipedia.org)

Lung cancer3

• Adenocarcinoma of the lung is the most common type of lung cancer, and like other forms of lung cancer, it is characterized by distinct cellular and molecular features. (wikipedia.org)
• Adenocarcinoma is more common in patients with a history of cigarette smoking, and is the most common form of lung cancer in younger women and Asian populations. (wikipedia.org)
• citation needed] Adenocarcinoma, like other forms of lung cancer, is usually advanced or metastatic at time of diagnosis. (wikipedia.org)

Neoplasms1

• Neoplasms containing cyst-like formations or producing mucin or serum. (lookformedical.com)

Commonly1

• Most cases of paraneoplastic AN involve an adenocarcinoma,[5] most commonly one arising in the gastrointestinal tract (stomach or liver[3] ) and less commonly in the lungs, ovaries, uterus, breasts, kidneys, prostate or bladder. (medscape.com)

Subtypes1

• Lung adenocarcinoma is further classified into several subtypes and variants. (wikipedia.org)

Mucus3

• Mucus hypersecretion contributes to the morbidity and mortality of smoking-related lung diseases, especially chronic obstructive pulmonary disease (COPD), which starts in the small airways. (biomedcentral.com)
• This strategy identified both mucus production and secretion related genes under control of a network composed of multiple transcription factors. (biomedcentral.com)
• This novel strategy enabled identification of a 73 "MUC5AC-associated core gene" list with 9 categories, which control a series of processes from mucin biosynthesis to mucus secretion. (biomedcentral.com)

Malignant1

• PANCREATIC DUCTAL ADENOCARCINOMA CLINICAL FEATURES Ductal adenocarcinoma of the pancreas is the most common malignant neoplasm of the pancreas. (coek.info)

Refers3

• The Chang sign refers to the dilatation and abrupt change in caliber of the main pulmonary artery due to pulmonary embolism 1 . (radiopaedia.org)
• Pulmonary hemosiderosis (PH) refers to iron deposition within the lung. (radiopaedia.org)
• Although the term " siderosis " strictly just means any deposition of surplus iron in the body, when used as a stand-alone term it usually refers to pulmonary siderosis. (radiopaedia.org)

Signs2

• It is one of several described signs of pulmonary embolus on chest radiographs . (radiopaedia.org)
• 1. Plain Film Signs in Pulmonary Embolism (with CT correlate), Kirwadi A, Bickle IC. (radiopaedia.org)

Squamous cell carc4

• Adenocarcinoma is the most frequently occurring subtype, constituting approximately 40% of all NSCLCs, with squamous cell carcinoma close behind, and "others" representing the remaining cases. (medscape.com)
• [ 7-9 ] Bevacizumab (Avastin, Genentech, South San Francisco, CA), in combination with carboplatin and paclitaxel, is not recommended for patients with squamous cell carcinoma because pulmonary hemorrhage occurs with greater frequency with bevacizumab in patients with this histologic subtype. (medscape.com)
• The most common paraneoplastic syndromes associated with adenocarcinoma of the lung are described below: Hypercalcemia of malignancy is more common in squamous cell carcinoma of the lung, but can occur in adenocarcinoma as well. (wikipedia.org)
• NSCLC accounts for ∼ 85% of all lung cancers and has multiple histological subtypes including adenocarcinoma and central squamous cell carcinoma . (amboss.com)

Signet ring cell1

• 20. Comparison of the immunophenotypes of signet-ring cell carcinoma, solid adenocarcinoma with mucin production, and mucinous bronchioloalveolar carcinoma of the lung characterized by the presence of cytoplasmic mucin. (nih.gov)

Minimally invasive adenocarcinoma1

• In this revised classification, a major update is the introduction of the terms adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA). (cap.org)

Mucinous adenocarcinoma1

• The provided sections demonstrate an invasive, non-mucinous adenocarcinoma of the lung with a wide range of histologic growth patterns. (cap.org)

Endocervical Adenocarcinoma1

• Molecular Correlates of Invasion Pattern in HPV-Associated Endocervical Adenocarcinoma: Emergence of Two Distinct Risk-Stratified Tiers. (stanford.edu)

Histologic2

• The pathophysiology of adenocarcinoma is complicated, but generally follows a histologic progression from cells found in healthy lungs to distinctly dysmorphic, or irregular cells. (wikipedia.org)
• Subsequent studies evaluating the prognostic significance of this classification system confirm that the predominant histologic pattern correlates well with survival, with lepidic predominant having the best prognosis, micropapillary and solid predominant the worst, and papillary and acinar predominant in between. (cap.org)

Alveolar3

• 3.0 cm) adenocarcinoma with growth restricted to neoplastic cells along preexisting alveolar structures (lepidic growth), lacking stromal, vascular or pleural invasion. (cap.org)
• MH - A549 Cells UI - D000072283 MN - A11.251.210.190.80 MN - A11.251.860.180.80 MN - A11.436.54 MS - An immortalized cell line derived from human ADENOCARCINOMA, ALVEOLAR basal epithelial cells isolated from the lungs of a male patient in 1972. (nih.gov)
• do not routinely add ADENOCARCINOMA, ALVEOLAR HN - 2017 MH - Abdominal Oblique Muscles UI - D000071596 MN - A2.633.567.50.375 MS - Muscles of the anterolateral abdominal wall consisting of the external oblique and the internal oblique muscles. (nih.gov)

Paraneoplastic syndromes1

• Late-stage disease can manifest with pulmonary symptoms, extrapulmonary symptoms, paraneoplastic syndromes (e.g., syndrome of inappropriate antidiuretic hormone secretion , hypercalcemia ), and/or signs of metastatic disease. (amboss.com)

Prognosis1

• A second major change in the IASLC/ATS/ERS classification is modification of the WHO category of "mixed subtype," which comprised roughly 85% of all lung adenocarcinomas and encompassed a wide variety of tumors with variable prognosis. (cap.org)

Histological1

• Pulmonary pneumocytoma is a rare benign tumor which is microscopically characterized by four main histological components (solid, papillary, sclerotic, and hemangiomatous) in varying proportions. (radiopaedia.org)

Nodule2

• Pulmonary sclerosing hemangioma manifesting as a nodule with irregular air clefts on high-resolution CT. (radiopaedia.org)
• Lung cancer may be diagnosed after the incidental discovery of a pulmonary nodule on imaging. (amboss.com)

Solitary1

• Solitary pulmonary nodules: dynamic enhanced multi-detector row CT study and comparison with vascular endothelial growth factor and microvessel density. (radiopaedia.org)

Peptide2

• The production of this hormonally active peptide by cancer cells causes increased bone resorption via upregulation of osteoclasts, one of the cells responsible for bone remodeling. (wikipedia.org)
• 18. Tumor-associated neoexpression of the pS2 peptide and MUC5AC mucin in primary adenocarcinomas and signet ring cell carcinomas of the urinary bladder. (nih.gov)

Lung cancers1

• Like many lung cancers, adenocarcinoma of the lung is often advanced by the time of diagnosis. (wikipedia.org)

Bladder1

• 19. Clinicopathologic features and utility of immunohistochemical markers in signet-ring cell adenocarcinoma of the bladder. (nih.gov)

Citation1

• citation needed] Adenocarcinoma, like other forms of lung cancer, is usually advanced or metastatic at time of diagnosis. (wikipedia.org)

Classification1

• In 2011, an updated classification of pulmonary adenocarcinoma was issued jointly by the International Association for the Study of Lung Cancer (IASLC), the American Thoracic Society (ATS) and the European Respiratory Society (ERS). (cap.org)

Chronic1

• Lung cancer is more closely linked to chronic obstructive pulmonary disease with airflow compromise than to the disease without significant airway obstruction. (medscape.com)

Infections1

• It is used as a model for PULMONARY ALVEOLI function and virus infections, as a TRANSFECTION host, and for PRECLINICAL DRUG EVALUATION. (nih.gov)

Demonstrate1

• Radiographs demonstrate a 2.5 cm solid, subpleural lesion with spiculated borders involving the left upper lobe. (cap.org)

Patients4

• Adenocarcinoma is more common in patients with a history of cigarette smoking, and is the most common form of lung cancer in younger women and Asian populations. (wikipedia.org)
• Less than 1% of patients with adenocarcinoma of the lung will exhibit this finding, but when it does occur, it is a poor prognostic factor. (wikipedia.org)
• 16. Immunohistochemical screening and fluorescence in situ hybridization confirmation of ALK translocation in lung adenocarcinoma and its clinicopathological significance: a single-center large-scale investigation of Chinese patients. (nih.gov)
• Namely, an increasing number of patients with IEIs present with severe dysregulations of the central nervous, digestive, renal or pulmonary systems. (cdc.gov)

Acinar2

• This case first appeared as Performance Improvement Program in Surgical Pathology (PIP) 2013, case 22, and is adenocarcinoma, predominantly acinar type. (cap.org)
• Taken in totality, the tumor is best classified as adenocarcinoma, predominantly acinar type. (cap.org)

Rare3

• Hypertrophic pulmonary osteoarthropathy (HPO) is fairly rare in adenocarcinoma. (wikipedia.org)
• Pulmonary pneumocytomas , previously known as pulmonary sclerosing hemangiomas (PSH) , are rare benign neoplasms of the lung . (radiopaedia.org)
• A rare tumor of the lung: pulmonary sclerosing hemangioma (pneumocytoma). (radiopaedia.org)

Features5

• Adenocarcinoma of the lung is the most common type of lung cancer, and like other forms of lung cancer, it is characterized by distinct cellular and molecular features. (wikipedia.org)
• 1. Pulmonary adenocarcinoma with signet ring features: Detailed cytomorphologic analysis. (nih.gov)
• 2. Cytomorphological features of ALK-positive lung adenocarcinomas: psammoma bodies and signet ring cells. (nih.gov)
• 17. Pulmonary epithelioid hemangioendothelioma with prominent signet ring cell features mimicking metastatic adenocarcinoma. (nih.gov)
• Histopathological and CT features of pulmonary sclerosing haemangiomas. (radiopaedia.org)

Primary3

• 6. ALK translocation is associated with ALK immunoreactivity and extensive signet-ring morphology in primary lung adenocarcinoma. (nih.gov)
• 7. Napsin-A, TTF-1, EGFR, and ALK Status Determination in Lung Primary and Metastatic Mucin-Producing Adenocarcinomas. (nih.gov)
• 12. Primary signet ring cell adenocarcinomas of the lung: a clinicopathological study of 15 cases. (nih.gov)

Cases1

• Sixteen cases of pulmonary sclerosing haemangioma: CT findings are not definitive for preoperative diagnosis. (radiopaedia.org)

Family1

• Among mucin (MUC) family members, MUC4 showed the greatest increase in the resistant versus parental sublines. (bvsalud.org)

Full1

• Thus, in epizootic adenomatosis X PULM ADENOMATOSIS, OVINE the Indexer must use the heading as given instead of typi PULMONARY ADENOMATOSIS, OVINE in full. (nih.gov)