Loading...
  • polymerase chain re
  • Using conventional histological (light and electron microscopic examinations), immunohistological (immunofluorescent and immunoperoxidase), and molecular histological (in situ hybridisation and polymerase chain reaction (PCR) in situ hybridisation) techniques, the immunopathology of uveitis has been studied using inflamed ocular tissue. (bmj.com)
  • vertebrate
  • Immunofluorescence with monoclonal and polyclonal antibodies against multiple epitopes of vertebrate titin further supports its localization to condensed mitotic human chromosomes, suggesting a role for titin not only in myofibrillar assembly and muscle elasticity, but potentially in the architecture of mitotic chromosomes. (rupress.org)
  • This allows us to conclude that the paralemmin gene family arose early and has been maintained throughout vertebrate evolution, suggesting functional diversification and specific biological roles of the paralemmin isoforms. (jove.com)
  • ventral
  • We show that Traf4 is required for efficient apical constriction during ventral furrow formation and for proper localization of Armadillo to the apical position in constricting cells. (asm.org)
  • 1996
  • Even though autoantibody production may be an epiphenomenon of autoimmune diseases, autoantibody targets in scleroderma are very specific ( White, 1996 ). (rupress.org)
  • mRNAs
  • Activation of IRE1 and ATF6 causes transcriptional activation of genes needed for folding in the ER, whereas PERK activation results in a general decrease in translation initiation and selective translation of specific mRNAs through phosphorylation of eIF2α. (biologists.org)
  • We propose that some mRNAs are more sensitive to eIF2α phosphorylation than others, and that this causes specific patterning defects. (biologists.org)
  • diagnosis
  • In clinical medicine, autoantibodies have been used to establish diagnosis, estimate prognosis, follow the progression of a specific autoimmune disease, and, finally, increase our knowledge of the pathophysiology of autoimmunity. (rupress.org)
  • molecular
  • 3 The messenger RNAs of many cytokines and growth factors can be detected by molecular histological techniques. (bmj.com)
  • This is the first report of molecular marker localization on algal chromosomes. (biomedsearch.com)
  • This research provides evidence for the benefit of using FISH for identifying molecular markers for sex identification, isolation of specific genes linked to this marker in the females, and sex determination of S. japonica gametophytes in the future. (biomedsearch.com)
  • nucleotide
  • Conversely, blocking the GDP-GTP nucleotide exchange reaction leads to constitutive Golgi localization, suggesting that Garz cycles in a GEF-activity-dependent manner between cytoplasmic and Golgi-membrane-localized pools. (biologists.org)
  • marker
  • Marker-assisted analysis of six BMP signaling components ( dpp, gbb, scw, tkv, sax, sog ) by RNA interference revealed that both serosa and amnion specification of M. abdita are dependent on BMP activity. (biologists.org)
  • A sex-specific marker is one of the best ways to make this determination. (biomedsearch.com)
  • Based on the known female-related FRML-494 marker, co-electrophoresis and Southern blot profiles demonstrated that it was inheritable and specific to female gametophytes. (biomedsearch.com)
  • CONCLUSIONS/SIGNIFICANCE: Our data suggest that this marker was a female chromosome-specific DNA sequence. (biomedsearch.com)
  • sequence
  • The paralemmin genes have also maintained specific features of gene organisation and sequence. (jove.com)
  • The completion of the human genome sequence, along with that of many other species, has highlighted the challenge of ascribing specific function to non coding sequences. (jove.com)
  • activation
  • According to this view, inappropriate UPR activation can cause specific patterning defects during embryo development. (biologists.org)
  • The heterotrimeric G protein, defined by its alpha-subunit Concertina, contributes to the localization and activation of RhoGEF2 ( 37 ). (asm.org)
  • further
  • Paralemmin-1 and palmdelphin were further duplicated in the teleost fish specific genome duplication. (jove.com)
  • evidence
  • Overexpression of CG11340 increased sensitivity to dietary copper, and RNAi and ends-out knockout of CG11340 resulted in copper tolerance, providing evidence for a specific nonneuronal role for this subunit in D. melanogaster . (g3journal.org)
  • common
  • The metazoan LGIC lineages expanded from clades present in the last common bilaterian ancestor, and extant metazoa now exhibit lineage-specific clades ( Dent 2006 ). (g3journal.org)