• Sister Mary Joseph nodule is associated with multiple peritoneal metastases and a poor prognosis. (wikipedia.org)
  • Sister Mary Joseph nodules represent metastases in the peritoneal cavity that enter the umbilicus usually from ovarian malignancy but can be seen in gastro-intestinal tumours including pancreas. (radiopaedia.org)
  • Metastases may cause a Sister Mary Joseph nodule. (wikipedia.org)
  • Sister Mary Joseph nodule is a well known cutaneous metastases. (radiopaedia.org)
  • Eligible adult patients have histologically confirmed colorectal adenocarcinoma, liver metastases measurable on computed tomography scan and untreatable by either surgical resection or local ablation, and they may have limited extra-hepatic disease, defined as ≤5 nodules in the lung and/or one other metastatic site which is amenable to future definitive treatment. (ox.ac.uk)
  • Yendluri V, Centeno B, Springett G. Pancreatic cancer presenting as a Sister Mary Joseph's nodule: case report and update of the literature. (wikipedia.org)
  • Nodules will also, rarely, originate from appendix cancer spillage and pseudomyxoma peritonei. (wikipedia.org)
  • In medicine, the Sister Mary Joseph nodule or more commonly node, also called Sister Mary Joseph sign, refers to a palpable nodule bulging into the umbilicus as a result of metastasis of a malignant cancer in the pelvis or abdomen. (wikipedia.org)
  • In medicine, the Sister Mary Joseph nodule or more commonly node, also called Sister Mary Joseph sign, refers to a palpable nodule bulging into the umbilicus as a result of metastasis of a malignant cancer in the pelvis or abdomen. (wikipedia.org)
  • The CT scan revealed a 3cm x 5cm mass involving the tail of the pancreas (Figure 1), as well as a 1.3cm nodule in the liver, likely representing a metastasis of the pancreatic primary. (ispub.com)
  • PET- CT revealed FDG avid thickening in the stomach with cutaneous nodules, skeletal and abdominal lymph nodes metastasis. (juniperpublishers.com)
  • The predominant manifestation of the cutaneous metastasis was a nodule or mass (73%) and the most common site of the skin lesion was non-umbilicus rather than umbilicus. (nih.gov)
  • Sister Mary Joseph nodules represent metastatic cancer of the umbilicus. (biomedsearch.com)
  • CT of the abdomen with oral and intravenous contrast revealed a large metastatic deposit in right lobe of the liver (Figure 1).Additionally an enhancing nodule was seen involving the rectus sheath at the level of the umbilicus (Figure 1). (appliedradiology.com)
  • Metastatic umbilical nodules are known as Sister Joseph's nodules (SJN), named after the brilliant first assistant to Dr. W.J. Mayo of theMayo Clinic. (appliedradiology.com)
  • We also have a rare and unusual metastatic presentation: 'giant' bilateral ovarian tumors and subcutaneous nodules, concurrently. (biomedcentral.com)
  • Sister Mary Joseph's umbilical nodule designates an exceptional location umbilical metastatic of cancer, which is generally often pelvic adenocarcinoma. (issr-journals.org)
  • Pancreatic cancer accounts for 7-9% of Sister Mary Joseph's nodules (2,3). (isciii.es)
  • Sister Mary joseph nodule as a presenting sign of pancreatobiliary adenocarcinoma. (biomedsearch.com)
  • We present here the case of a 30-year-old nullipara, who had an umbilical nodule (Sister Mary Joseph's) and was found on imaging to have a pelvic tumor which was suspected to be an ovarian cancer. (scirp.org)
  • In this issue's Clinical Vistas Briefs, readers are asked to determine the cause of an ulcerated umbilical nodule and vaginal bleeding in a 62-year-old woman and to diagnose isolated purple stripes on the back of a 15-year-old boy (page 929 ). (cmaj.ca)
  • Cutaneous nocardiosis can present as subcutaneous nodules with pustules, abscesses with sinus tract formation, ulcers, granulomas or lymphocutaneous infection. (clinmedjournals.org)
  • A periumbilical mass is not always a Sister Mary Joseph nodule. (wikipedia.org)
  • 3 Additionally, owing to the increasing number of cross-sectional imaging performed in patients under evaluation for malignancies, the radiologist may be the first to diagnose a periumbilical nodule. (appliedradiology.com)
  • Medical imaging, such as abdominal ultrasound, may be used to distinguish a Sister Mary Joseph nodule from another kind of mass. (wikipedia.org)
  • 4 On contrast CT they have been reported to appear as solid well-defined, enhancing lesions encompassing 3 forms: subcutaneous nodule, dermal deposits, or peritoneal mass extending into the anterior abdominal wall. (appliedradiology.com)
  • A 44-year-old male presented with complaints of multiple nodules over the body, abdominal discomfort, loss of appetite and loss of weight for 2 months. (juniperpublishers.com)
  • On further evaluation, Contrast enhanced computed tomography (CECT) of the chest and abdomen showed multiple tiny nodules in bilateral lungs, multiple mediastinal lymph nodes, multiple soft tissue deposits in the anterior abdominal wall, left chest wall as well as intramuscular deposits in right gluteal muscle with suspicious mural thickening in gastroesophageal junction, cardia and body of stomach. (juniperpublishers.com)
  • Umbilical nodules should prompt clinical evaluations, as these tumors are usually associated with poor prognosis. (biomedsearch.com)
  • Valderrabano P, Khazai L, Thompson ZJ, Otto KJ, Hallanger-Johnson JE, Chung CH, Centeno BA, McIver B. Association of Tumor Size With Histologic and Clinical Outcomes Among Patients With Cytologically Indeterminate Thyroid Nodules. (moffitt.org)
  • Histologically most nodules are adenocarcinomas although squamous cell carcinoma, carcinoid, and lymphoma have also been reported. (appliedradiology.com)
  • Atypical fibroxanthomas (AFX) are rare cutaneous tumors, which typically present as a solitary ulcerated papule or nodule on sun-damaged skin. (bvsalud.org)
  • We report a rare case of primary lung cancer with presentation of multiple pulmonary nodules in a 62-year-old male laborer by occupation, chronic smoker (40 pack-years) who presented with 6 month history of dry cough, exertional breathlessness and fever off and on. (ccij-online.org)
  • Nodules will also, rarely, originate from appendix cancer spillage and pseudomyxoma peritonei. (wikipedia.org)
  • This nodule may indicate cancer or designates a recurrence. (issr-journals.org)
  • Upon physical examination, asymptomatic violaceous nodules were observed on the right anterior axillary fold, occipital scalp, chest and abdomen (Fig. 1). (nih.gov)
  • Sister Mary Joseph nodules can be painful to palpation. (wikipedia.org)
  • Endometriosis -the endometrial tissue outside the uterus-can present as a painful nodule in the belly button that can bleed during menstruation (32) . (ehealthstar.com)
  • 5 This may manifest as a morphologically firm nodule, a profound node, an indurated plaque or nodule with a vascular appearance, an uncharacteristic diffuse hardening of the umbilical region, or as a fissured and ulcerated lesion with some fetid discharge. (ispub.com)
  • The eponymous term Sister Mary Joseph nodule was coined in 1949 by Hamilton Bailey. (wikipedia.org)
  • The authors report the case of a Sister Mary Joseph nodule originating from the bifurcation of the common hepatic duct. (biomedsearch.com)
  • But there is one condition called Sister Mary Joseph nodule which is common in the advanced stage. (demoslab.org)
  • Sister Mary Joseph Dempsey (born Julia Dempsey) was a Catholic nun and surgical assistant of William J. Mayo at St. Mary's Hospital in Rochester, Minnesota from 1890 to 1915. (wikipedia.org)
  • She drew Dr. Mayo's attention to the nodule and he published the first article about it in 1928. (blogspot.com)
  • We perform a brief review of umbilical nodules. (bvsalud.org)