• This is a "connection" page, showing publications James Liao has written about Proto-Oncogene Proteins c-sis. (uchicago.edu)
  • Proto-Oncogene Proteins c-mdm2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • This graph shows the total number of publications written about "Proto-Oncogene Proteins c-mdm2" by people in this website by year, and whether "Proto-Oncogene Proteins c-mdm2" was a major or minor topic of these publications. (umassmed.edu)
  • Below are the most recent publications written about "Proto-Oncogene Proteins c-mdm2" by people in Profiles. (umassmed.edu)
  • Proto-Oncogene Proteins p21(ras)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
  • Below are the most recent publications written about "Proto-Oncogene Proteins p21(ras)" by people in Profiles. (uchicago.edu)
  • A specialized protein structure at the centromere region on a sister chromatid. (freezingblue.com)
  • Interestingly Ctcf is definitely a zinc finger DNA binding protein that regulates transcription governs enhancer function and is involved in sister chromatid cohesion. (healthyguide.info)
  • It encodes a protein that prevents separin from promoting sister chromatid separation during mitosis [ 3 ]. (biomedcentral.com)
  • In order to provide each daughter cell with the exact right set of 46 chromosomes, the sister chromatids are stably entrapped by large, circular protein complex named cohesins. (amsterdamumc.org)
  • The pituitary tumour transforming gene (PTTG), also known as securin, is a mitotic checkpoint protein which inhibits sister chromatid separation during mitosis. (birmingham.ac.uk)
  • The synonymous codons were assumed to be neutral and to have no effect on the transgenic proteins, and presumed to be safe [2] ( Bt Toxins in Genetically Modified Crops: Regulation by Deceit , SiS 22). (i-sis.org.uk)
  • Cellular DNA-binding proteins encoded by the sis gene ( GENES, SIS ). (nih.gov)
  • However, unlike oncogenes such as PDGFB or ras, Wnt-1 and -2 failed to induce detectable transformed foci following transfection, and stable NIH3T3 transfectants lacked tumor forming capacity. (tau.ac.il)
  • I began a very specific treatment, the targeted gene therapy, based on my genes that were oncogenes. (burzynskipatientgroup.org)
  • DNA from both transformed and tumor cells derived from transformed cells were subjected to differential PCR to detect changes in gene copy number and gene expression of five proto-oncogenes (K-ras, c-fos, c-jun, sis, erb-B2) and two tumor supressor genes (p53, p16). (cdc.gov)
  • Tumor cells showed increased copy number of the K-ras gene and increased expression of c-fos, erbB2 and K-ras, while c-myc and sis were under expressed. (cdc.gov)
  • Sepased, an enzyme for resolving the cohesion of Chromatide Sister, is an oncogene and overexpressed in many human cancer. (separase.com)
  • The region of a chromosome where two sister chromatids are joined and where spindle microtubules attach during mitosis and meiosis. (freezingblue.com)
  • The resulting sister chromatid cohesion allows sister chromatids to be orderly aligned in metaphase and attached to microtubules from opposite poles. (amsterdamumc.org)
  • the process that duplicated chromosomes (the sister chromatids) remain connected from the time of their synthesis in S-phase until their separation in anaphase, to allow the proper distribution of DNA over two new daughter cells. (amsterdamumc.org)
  • The goal of cell division is to separate the duplicated sister chromatids (in figure above in red) with the help of the mitotic spindle (in green). (unige.ch)
  • In addition, cohesion loss can be detected in many cancer cell lines, upon activation of oncogenes in normal cells and by genetic or pharmacological perturbation of DNA replication. (amsterdamumc.org)
  • In our lab, we try to answer questions such as: how does oncogenic transformation affect sister chromatid cohesion? (amsterdamumc.org)
  • How does the DNA helicase DDX11 (mutated in the cohesinopathy Warsaw Breakage Syndrome) contribute to replication fork progression, sister chromatid cohesion and DNA damage response? (amsterdamumc.org)
  • This will increase our understanding of the complex interplay between sister chromatid cohesion and DNA replication, and may provide clinical opportunities if specific vulnerabilities of cancer cells with defective cohesion can be found and targeted. (amsterdamumc.org)
  • Overexpression of c-sis causes tumorigenesis. (nih.gov)
  • Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis. (umassmed.edu)
  • Oncogene is a peer-reviewed scientific journal published under the Nature Portfolio addressing cancer cell genetics and the structure and function of oncogenes. (wikipedia.org)
  • Oncogene received a 2021 impact factor of 8.756 and received Journal Citation Reports rankings of 38th out of 245 journals in the category Oncology, 16th out of 175 in the category Genetics & Heredity, 41st out of 194 in the category Cell Biology, and 40th out of 296 in the category Biochemistry & Molecular Biology. (wikipedia.org)
  • LncRNA NEAT1 acts as an oncogene and contributes to the development of HCC. (bvsalud.org)
  • this may be in part because they have a higher rate of triple-negative breast cancer (negative for estrogen and progesterone receptors and human epidermal growth factor receptor [HER2] oncogene), which has a poorer prognosis than other types. (msdmanuals.com)
  • These findings establish that both Wnt signaling and pattern of growth alterations differ from those of oncogenes which activate proliferative signaling pathways in NIH3T3 cells. (tau.ac.il)
  • ESPL1 / separase, a cysteine ​​endopeptidase, is a key player in centrosome duplication and mitotic sister chromatid separation. (separase.com)
  • This gene product is involved in cell cycle progression, p53-mediated apoptosis, transcription activator of several other oncogenes [ 4 ] and DNA repair [ 5 ]. (biomedcentral.com)
  • D1 was originally identified as a candidate oncogene activated inside a subset of parthyroid tumors through genetic rearrangement [1]. (healthyguide.info)
  • An open access online-only sister journal, Oncogenesis, was established in 2012 by Douglas R. Green, who was then Oncogene's editor-in-chief. (wikipedia.org)
  • While none of the transformed cells showed changes in gene amplification, increases in the expression of c-jun and p16 were observed and sis was under expressed. (cdc.gov)
  • Chromosomal instability and aneuploidy are not only symptoms of cancer cells, they can directly cause or enhance cancer formation, as they create dosage imbalances between oncogenes and tumour suppressors, and contribute to the development of cancer drug resistances. (unige.ch)
  • A. Oncogenes in Phylogeny Neoplasia is not limited to human beings, or to mammals, but develops in all taxonomic groups of recent Eumetazoa and even in multicellular plants. (science-connections.com)
  • Nevertheless, there has been an apparent "marked deterioration of health" reported with the introduction of GM crops based on inspection of official data (see [10] Scientific American Disinformation on GMOs , SiS 60). (i-sis.org.uk)
  • My husband, twin sister and I researched and we found ourselves at the Burzynski clinic in mid-January 2010. (burzynskipatientgroup.org)
  • Serum oncogene proteins in hazardous-waste workers. (cdc.gov)
  • A study of serum oncogene proteins in hazardous waste workers was conducted. (cdc.gov)
  • Blood samples were collected and analyzed for nine oncogene proteins by a serum immunoblotting technique with monoclonal antibodies. (cdc.gov)
  • Transforming proteins coded by sis oncogenes. (nih.gov)
  • Proto-Oncogene Proteins c-met" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • This graph shows the total number of publications written about "Proto-Oncogene Proteins c-met" by people in this website by year, and whether "Proto-Oncogene Proteins c-met" was a major or minor topic of these publications. (umassmed.edu)
  • Below are the most recent publications written about "Proto-Oncogene Proteins c-met" by people in Profiles. (umassmed.edu)
  • The proto-oncogene c-sis codes for a growth factor which is the B chain of PLATELET-DERIVED GROWTH FACTOR. (bvsalud.org)
  • v-sis Platelet Derived Growth Factor beta polypeptide is the viral homologue of PDGFB. (medindex.am)
  • 2. Expression of proto-oncogenes in xenografts of human renal cell carcinomas. (nih.gov)
  • 19. Comparative analysis of the human and feline c-sis proto-oncogenes. (nih.gov)
  • Only two workers had trace positive bands (less than a two fold increase above background) for the ras oncogene protein. (cdc.gov)
  • In the previous study, 10 workers were positive for at least one serum oncogene protein of type ras, fes, or sis. (cdc.gov)
  • Chronic inhalation exposure to environmental carcinogens such as polycyclic aromatic hydrocarbons (PAHs), cigarette smoke, 4‐aminobiphenyl (4‐ABP), ethylene oxide, and styrene is associated with elevations in biomarkers such as DNA adducts, protein adducts, sister chromatid exchanges (SCEs), chromosomal aberrations, gene mutation, and/or oncogene activation. (nyu.edu)
  • Oncogene Protein p21(ras)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
  • Transforming protein encoded by ras oncogenes. (uams.edu)
  • Oncogene protein p21(ras) has been directly implicated in human neoplasms, perhaps accounting for as much as 15-20% of all human tumors. (uams.edu)
  • Below are the most recent publications written about "Oncogene Protein p21(ras)" by people in Profiles over the past ten years. (uams.edu)
  • 11. The Hardy-Zuckerman 2-FeSV, a new feline retrovirus with oncogene homology to Abelson-MuLV. (nih.gov)
  • PDGF is the major serum polypeptide mitogen for cells of mesenchymal origin and has two dissimilar subunits, A and B. The B chain has homology to SIS and is alone sufficient for mitogenesis. (medindex.am)
  • 14. Human cytomegalovirus (strain AD169) contains sequences related to the avian retrovirus oncogene v-myc. (nih.gov)
  • Secuencias de ADN asociadas a retrovirus (v-sis) originalmente aisladas del virus del sarcoma simio (SSV). (bvsalud.org)
  • Retrovirus-associated DNA sequences (v-sis) originally isolated from the simian sarcoma virus (SSV). (bvsalud.org)
  • 10. Aberrant oncogene expression in uncultured human sarcoma and melanoma. (nih.gov)
  • Identification of 5' human c-sis coding sequences that are not homologous to the transforming gene of simian sarcoma virus. (nih.gov)
  • 4. Molecular cloning of the feline c-fes proto-oncogene and construction of a chimeric transforming gene. (nih.gov)
  • 1. Expression of the human fes cellular oncogene in renal cell tumors. (nih.gov)
  • 3. Expression of cellular oncogenes in primary cells from human acute leukemias. (nih.gov)
  • 5. Specific expression of cellular oncogenes c-myc and c-myb in T-cell lines established from three types of bovine lymphosarcomas. (nih.gov)
  • 9. Expression of cellular oncogenes in teratoma-derived cell lines. (nih.gov)
  • 17. Different pattern of expression of cellular oncogenes in human non-small-cell lung cancer cell lines. (nih.gov)
  • Mutations in the c-met proto-oncogene are associated with papillary renal carcinoma and other neoplasia. (umassmed.edu)
  • The authors conclude that the occurrence of only two cases of oncogene activation suggests that the workers have minimized their exposures to hazardous wastes by wearing protective clothing and equipment and observing appropriate work practices. (cdc.gov)
  • Activation of the ras oncogene in the two workers may be a reflection of their cigarette smoking. (cdc.gov)
  • Identification of anaplastic lymphoma kinase (ALK) as an NB oncogene raised the possibility of using ALK tyrosine kinase inhibitors (TKIs) in treatment of patients with activating ALK mutations. (scilifelab.se)
  • Oncogene is a peer-reviewed scientific journal published under the Nature Portfolio addressing cancer cell genetics and the structure and function of oncogenes. (wikipedia.org)
  • Il faut une quan-tité remar-quable de coor-di-na-tion pour faire ce que fait le cancer, en exploi-tant parfai-te-ment et de manière répé-tée le fonc-tion-ne-ment élaboré du cycle cellu-laire. (lebonheurestpossible.org)
  • Another peculiar sign on presentation is known as a 'Sister Mary Joseph nodule,' which is an occasionally painful lump in the umbilicus secondary to metastatic cancer in this location (Figure 1). (sarcomahelp.org)
  • Strângerea de fonduri s-a încheiat Despre Barb Taylor, for all of her years, a loving mother, daughter, sister, wife, friend, and a dedicated kindergarten teacher for 24 years at Egyptian School in Tamms, IL. (constiintaortodoxa.ro)
  • This method allowed, for the first time, the reconstruction of the C-MYC ( a proto-oncogene ) activated network that is important for the induction of a series of malignancies and tumours. (unibo.it)
  • Oncogene received a 2021 impact factor of 8.756 and received Journal Citation Reports rankings of 38th out of 245 journals in the category Oncology, 16th out of 175 in the category Genetics & Heredity, 41st out of 194 in the category Cell Biology, and 40th out of 296 in the category Biochemistry & Molecular Biology. (wikipedia.org)
  • PDGFRB is a receptor tyrosine kinase and has been implicated in atherogenesis and in cell transformation by the SIS oncogene. (thermofisher.com)
  • Mom, Sister, Grand mom (some cases) doubles a woman's risk. (kindystores.com)
  • El proto-oncogén c-sis codifica un factor de crecimiento que es la cadena B del FACTOR DE CRECIMIENTO DERIVADO DE PLAQUETAS. (bvsalud.org)