• Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis:​ implications for the microanatomic and cellular mechanisms of bone loss. (lievers.net)
  • Trabecular bone density and loading history:​ regulation of connective tissue biology by mechanical energy. (lievers.net)
  • Bone histomorphometry:​ analysis of trabecular bone dynamics. (lievers.net)
  • Fyhrie DP, Carter DR. A unifying principle relating stress to trabecular bone morphology. (lievers.net)
  • Most studies investigating human lumbar vertebral trabecular bone (HVTB) mechanical property-density relationships have presented results for the superior-inferior (SI), or "on-axis" direction. (asme.org)
  • CT allows both the acquisition of bone morphology and measurement of bone density in a living individual. (hindawi.com)
  • While weight-bearing activity is generally thought to increase bone density, a new study finds that for preadolescent and adolescent girls, too much high-impact activity can lead to stress fractures. (sciencedaily.com)
  • When the researchers adjusted for other risk factors (age, later onset of menstruation and family history of osteoporosis and low bone density), the association between high-impact sports and fractures only strengthened. (sciencedaily.com)
  • Simulation of formation of inversion channel (electron density) and attainment of threshold vol-tage (IV) in a nanowire MOSFET. (wikipedia.org)
  • In calculating the net change in local bone apparent density, the technique takes into account the bone surface area available for osteoblastic and osteoclastic activity. (lievers.net)
  • Influence of physical activity on the regulation of bone density. (lievers.net)
  • Simulation tools-such as finite element analysis and computational fluid dynamics-are used in many disciplines to recreate expected and unexpected outcomes in the development stage of a range of products. (fda.gov)
  • Its "secret sauce" is using finite element analysis (FEA) simulation to see how the bone would perform in real activities, so surgeons can reduce the amount of hardware needed and improve stability. (3dprint.com)
  • As bone adapts to changes of these mechanical loads, according to Wolff's law, TKR will thus lead to bone remodeling. (utwente.nl)
  • This model was used to develop a system to analyze the stresses on the teeth and supporting bone structure during occlusion based on the finite element method and to examine the possibility of mechanical simulation. (hindawi.com)
  • The mechanical properties of bone are so fundamental to the ability of our skeletons to support movement, provide protection for our vital organs and ultimately affect our quality of life. (cgw.com)
  • Dr. Srivastava specializes in Mechanical Engineering has a deep knowledge of areas including dynamics and control systems, numerical modeling and simulation, and mechanics of materials. (exponent.com)
  • There is an increasing and unfulfilled demand of bone substitutes with optimal mechanical ---------------------------------------------------------------------------------------------------------------------------------------- Potential applications of portland cement on bone tissue engineering. (udea.edu.co)
  • We postulate that genotype, systemic metabolic conditions, and local tissue interactions establish the level of local tissue mechanical stimulation (attractor state) appropriate for the maintenance of bone tissue. (lievers.net)
  • The mechanical behaviour of cancellous bone. (lievers.net)
  • Quantitative Response of Bone to Mechanical Stress [PhD thesis]. (lievers.net)
  • Osteoregulatory nature of mechanical stimuli:​ function as a determinant for adaptive remodeling in bone. (lievers.net)
  • Influences of mechanical stress on prenatal and postnatal skeletal development. (lievers.net)
  • I hope that mechanical computer models will be accepted in medicine to a greater extent, both to improve the diagnosis of diseases, and to predict disease development and how different treatment methods can affect a patient. (lu.se)
  • Zumbrunn said it all starts with a broken bone, but complex fractures have a high rate of re-operation, and the surgeries themselves are often inefficient. (3dprint.com)
  • 2. The spine shortens and bones lose calcium putting a person at higher risk for fractures. (who.int)
  • Femoral acetabular impingement (FAI) is thought to be a key underlying reason for the development of osteoarthritis of the hip. (biomedcentral.com)
  • Sagittal slices (n=9) of femoral porcine cartilage-bone, 10 mm thick, were loaded using a five-axis custom test machine with a curved (radius 90 mm) steel indenter. (biomedcentral.com)
  • Relationships between loading history and femoral cancellous bone architecture. (lievers.net)
  • A femoral stem may be tightly packed at the neck for stiffness, then transition to a porous foam at the bone interface. (am-material.com)
  • For hips, lattice femoral stems and acetabular cups promote bone ingrowth for biological fixation. (am-material.com)
  • Characterization of bone marrow-derived mesenchymal /j.yexcr.2008.11.013 Baker N, Boyette L, Tuan-R S. 2015. (udea.edu.co)
  • The software upgrade enables the systems to mimic porous bone structures, fibrotic tissue, and ligaments so medical professionals can create models that behave just like human bone. (cgw.com)
  • The compressive behavior of bone as a two-phase porous structure. (lievers.net)
  • Dr. Srivastava has deep experience in scientific programming, numerical modeling and simulation using Matlab and Octave, as well as experience with finite difference and finite element methods for dynamic simulations. (exponent.com)
  • Mathematical modeling and numerical solutions for functionally dependent bone remodeling. (lievers.net)
  • Thus, it is assumed that the data can be utilized for 3D FE modeling with material properties set precisely to reflect the detailed morphology and internal bone structures. (hindawi.com)
  • This included the database development and business accounting structures for automating client/medical records. (hubpages.com)
  • Three-dimensional (3D) printed patient-specific implants are becoming increasingly popular as these can be customized to avoid critical structures, achieve perfect alignment to individual bone contours, and may provide better stability. (frontiersin.org)
  • One example is cellular lattice structures with bone-like porosity. (am-material.com)
  • A three-dimensional finite element model of the lower first premolar, with the three layers of enamel, dentin, and pulp, and the mandible, with the two layers of cortical and cancellous bones, was directly constructed from noninvasively acquired CT images. (hindawi.com)
  • Researchers at the Computational Mechanics and Experimental Biomechanics Lab at Tel Aviv University conducted a clinical evaluation of the characteristics of bone models that were 3D printed on the Digital Anatomy system, specifically focusing on how accurately they replicated screw pull-out force and driving torque using cortical and cancellous screws. (cgw.com)
  • Bone remodeling, I:​ theory of adaptive elasticity. (lievers.net)
  • The purpose of the current study was to look at the effects of cam-type impingement on the generation of shear strains at the bone/cartilage interface, using both experimental and finite element simulation methods. (biomedcentral.com)
  • Maximal shear strain was found at the cartilage-bone interface, and was a function of compressive loading level. (biomedcentral.com)
  • The results of this study indicate high shear strain at the bone/cartilage interface is a possible mechanism leading to cartilage delamination, and may be the mechanism behind cartilage degradation in patients with cam-type FAI. (biomedcentral.com)
  • My research team has driven the development of mechanobiological prediction models forward, previously for bones and recently for cartilage and tendons. (lu.se)
  • The second goal was to compare the outcomes of these remodeling simulations with clinical dual energy X-ray absorptiometry (DEXA) data. (utwente.nl)
  • The post-operative bone remodeling was simulated to resemble 5 years of clinical time after surgery. (utwente.nl)
  • In the clinical data the BMD in the medial ROI on average decreased from 0.97 to 0.57 g/cm2, while in simulations each of the models showed different behavior. (utwente.nl)
  • The distal ROI on average had an almost constant BMD value in the clinical data around 0.75 g/cm2 but did increase from 0.53 to 0.72 g/cm2 in the simulation results. (utwente.nl)
  • This can be attributed to a number of uncertainties and assumptions in both the clinical data, like unknown patient activity and measurement errors in the BMD data and in the FE model, like the bone remodeling algorithm, the applied boundary conditions, used alignments and used implant orientations. (utwente.nl)
  • EDEN PRAIRIE, MN & REHOVOT, Israel - 3D printing leader Stratasys Ltd. has enhanced its J750 Digital Anatom 3D printer with advanced bone capabilities that don't just look real but are actually biomechanically realistic, backed by clinical research. (cgw.com)
  • Parfitt AM. The physiologic and clinical significance of bone histomorphometric data. (lievers.net)
  • In addition, we develop better diagnostic methods for musculoskeletal diseases such as osteoarthritis, by combining knowledge from clinical images with computer simulation models. (lu.se)
  • High-fidelity haptic and visual rendering for patient-specific simulation of temporal bone surgery. (wikipedia.org)
  • In contrast, whether inserting a screw or drilling or sawing a bone, medical professionals can expect haptic feedback from Digital Anatomy models that is very realistic, and each model can be created from an actual patient scan. (cgw.com)
  • The 2020 study concluded that orthopedic screws pull-out force in the 3D-printed models had a similar haptic response to human cadaver bone. (cgw.com)
  • The hospital will have a state-of-the-art robotics, haptic, and surgical-medical simulation center. (embracingtheworld.org)
  • The net daily rate of apposition or resorption on a bone surface is determined by the difference between the actual stimulus and the tissue attractor state and can be modulated by other biologic factors. (lievers.net)
  • Reports have demonstrated that fluoxetine hydrochloride can induce bone resorption in rats by blocking 5-HT reuptake 10 . (bvsalud.org)
  • Potential applications of portland cement on bone tissue engineering. (udea.edu.co)
  • Tissues cultured in the multi-organ chip (from left to right: skin, heart, bone, liver, and endothelial barrier) maintained their tissue-specific structure and function after being linked by vascular flow. (columbia.edu)
  • A tendon transfer involves moving the tissue that connects human muscles to bones to help restore movement to a part of the body like a hand or foot. (cnet.com)
  • Tailored implants better match a patient's bone contours, improving short and long term fixation. (am-material.com)
  • Meta thinks the key to improving these avatars could be in learning more about the bones, muscles and joints that make up the human body's musculoskeletal system. (cnet.com)
  • This musculoskeletal simulation can perform complex movements such as twirling a pen. (cnet.com)
  • It's a broad subject, but my research focuses on the musculoskeletal system's tissues, i.e. bones, joints, and tendons. (lu.se)
  • Off-the-shelf manufactured bone models also lack those patient-specific characteristics, and other traditional 3D printing solutions are biomechanically unrealistic. (cgw.com)
  • In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. (lu.se)
  • As a graduate student, Bruckner accepted what she was taught, that the foot, a bewildering heap of 26 bones and 23 joints, is a marvelous biomechanical contraption that propels humans with speed and remarkable control-proof of evolutionary adaptation. (discovermagazine.com)
  • Facebook parent company Meta said it's created a new AI platform that builds realistic simulations of the muscles, bones and joints that enable humans to move. (cnet.com)
  • The transformation of the Resident Temporal Bone Laboratory into an advanced simulation and wellness space is one of the Department of Otorhinolaryngology-Head and Neck Surgery's key priorities. (montefiore.org)
  • We resolve the spatio-temporal development of the disease spread through the population in great detail and are able to find non-trivial correlations of infection and fatality rares with a variety of societal factors. (lu.se)
  • In this light, a mathematical model that considers hematopoietic dynamics in the diseased state of the bone marrow and peripheral blood is proposed and used to address findings about CSCs. (ebi.ac.uk)
  • We performed targeted molecular dynamics simulation to obtain trajectory of conformational change from inactive to active form. (intechopen.com)
  • Model analyses and simulations suggest that the emergence of the cancer stem cell population alongside other malignant cells engenders higher dimensions of complexity in the evolution of malignancy in the bone marrow and peripheral blood at the expense of healthy hematopoietic development. (ebi.ac.uk)
  • On the five-year horizon, we intend to create a state-of-the-art simulation lab facility for training otolaryngology residents and students in procedural skills. (umc.edu)
  • Her focus has been on using state-of-the-art simulation to transform pediatric training and education. (cgw.com)
  • Covering the key areas including the properties of biomaterials, common measuring techniques and modelling, Biomechanics of the Musculo-skeletal System, Third edition also integrates historical aspects thus building a bridge between old and familiar knowledge and the latest developments in biomechanics. (chipsbooks.com)
  • Roesler H. The history of some fundamental concepts in bone biomechanics. (lievers.net)
  • A specifically designed cryogenic probe was applied to the spinal cord for one minute through the created bone defect. (frontiersin.org)
  • Using a 3D surface model for the mandible, four plate designs were created and evaluated for their properties to stabilize a defined 30 mm critical-size bone defect. (frontiersin.org)
  • Donations to the Otolaryngology Resident Unrestricted Fund support every aspect of resident education and development. (umc.edu)
  • Today, a team of researchers from Columbia Engineering and Columbia University Irving Medical Center reports that they have developed a model of human physiology in the form of a multi-organ chip consisting of engineered human heart, bone, liver, and skin that are linked by vascular flow with circulating immune cells, to allow recapitulation of interdependent organ functions. (columbia.edu)
  • After establishing the human body simulation recognition model, use MATLAB to extract the K bone information. (hindawi.com)
  • From 1997 through 2003, he was Fellow and Scientific Advisor at Intuitive Surgical in Mountain View, CA. He joined the faculty at Stanford in 1999 where his research has focused on the design of robots for interaction with and near humans as well as haptics and surgical simulation. (wikipedia.org)
  • My primary research goals are to understand why children with ASD often tune out from the social world and how this impacts social skill and brain development, and to identify remediation strategies that motivate children with ASD to engage in social interactions. (stanford.edu)
  • An increasingly important aspect of the research work at ZIH is the development of algorithms for modeling the biological processes that occur in cells. (tu-dresden.de)
  • Currently, the startup offers three products - Lite, Research, and Libraries - for different levels of simulation use. (3dprint.com)
  • In addition, as the Director of Research and Development for the OpenSim software project, she guides the project's development team and serves as the voice of the software user/researcher. (stanford.edu)
  • With the development of image recognition and pattern recognition, action recognition has become a hot research direction in the field of computer actions. (hindawi.com)
  • This research could accelerate development of prosthetics, physical rehab, and surgery techniques. (cnet.com)
  • The idea with this ongoing large- scale activity, which addresses all industrial sectors, is to identify the most important strategic areas for Sweden where industry, the public sector and academia should collaborate to boost research, development and innovation. (lu.se)
  • Journal of Bone and Mineral Research. (lu.se)
  • Salisbury's work is organized around the following topics: Robot Hands:multi-finger hand mechanisms, control systems and perception techniques Haptics: interfaces and rendering techniques Robot Arms:force controllable robotic arms Personal Robotics: robots to work near and with humans, HRI Medical Robotics: user interfaces and surgical simulation Salisbury, J.K., Jr. (1999). (wikipedia.org)
  • It's going to decrease surgical time, it's going to decrease morbidity and mortality, and help us decrease anesthesia time, which is better for brain development. (cgw.com)
  • CustomSurg, which also provides 3D printed bone models and a virtual surgical plan, is in the proof of concept phase, and working on a patent application related to its core process. (3dprint.com)
  • Its treatment often requires aggressive surgical removal of bone. (frontiersin.org)
  • Development Goals (SDGs). (who.int)
  • The aging simulation exercise individualizes the effects of physiological aging by forcing students to experience functional losses. (who.int)
  • The aim of this work is to analyze different design techniques, which can later be used for the development of implants made of biocompatible materials. (frontiersin.org)
  • FGM hip implants better replicate the performance of natural bone. (am-material.com)
  • They help avert issues like bone atrophy and thigh pain associated with traditional implants. (am-material.com)
  • Human bone is expensive, difficult to obtain, and hard to acquire with the precise pathology characteristics needed, such as with tumors or reflecting different ages. (cgw.com)
  • Together, results provide novel support for the hypothesis that deficits in representing the reward value of social stimuli, including the human voice, impede children with ASD from actively engaging with these stimuli and consequently impair social skill development. (stanford.edu)
  • Simulations of the model are carried out by considering various parameter scenarios that reflect different experimental situations involving disease evolution in human hosts. (ebi.ac.uk)
  • The medical industry has traditionally used human bone from cadavers, or legacy 3D printing solutions, all of which have proven inadequate. (cgw.com)
  • The development of the human blood-CSF-brain barrier. (cdc.gov)
  • The simulation and calculation techniques developed herein were applied to a set of human subject data that were acquired for a purpose other than evaluating aluminum. (purdue.edu)
  • The human subject data included both bone Al from NAA and fingernail Al from mass spectrometry measurements. (purdue.edu)
  • Senior capstone design introduces Biomedical Engineering students to the development of products of real-life impact on human health. (cmu.edu)
  • Functional adaptation in long bones:​ establishing in vivo values for surface remodeling rate coefficients. (lievers.net)
  • Design of novel in vivo neutron activation analysis system for noninvasive quantification of Mn in bone with Monte Carlo simulations. (cdc.gov)
  • Unlike other known experimental methods of SCI simulation (compression, contusion, etc.), the proposed technique is characterized by minimal invasiveness, high precision, and reproducibility. (frontiersin.org)
  • Through simulation and calculation, it was demonstrated that the NAA experimental parameters resulted in an elevated detection limit for aluminum that is above Al skeletal loads observed in healthy individuals. (purdue.edu)
  • The ensuing model, resulting from a modification and refinement of a recent model, develops out of the position that mathematical models of CSC development, that are few at this time, are needed to provide insightful underpinnings for biomedical findings about CSCs as the CSC idea gains traction. (ebi.ac.uk)
  • Three of the simulations showed an increase in BMD over time and two of the simulations showed a decrease over time. (utwente.nl)
  • In the simulations an average decrease from 0.35 to 0.20 g/cm2 was observed. (utwente.nl)
  • Several drugs cross the placental barrier and some have teratogenic effects on the fetus, which may cause dysfunction and disorders during embryonic development, particularly during the first three months of intrauterine life 2 . (bvsalud.org)
  • Symptoms related to bone marrow dysfunction, such as anemia, leukopenia, or thrombocytopenia, are rare at presentation but can also be observed in the later stages of the disease. (medscape.com)
  • During the entire study period (days 1-60 of the post-trauma period), the necrotic processes and the development of the glial scar (lesion evolution) were contained in the surgically approached vertebral space (Th13). (frontiersin.org)
  • Answering questions from the judges, Mir explained that the software simulates parts in their production processes, has a current total revenue of around $70k, and is focused on expanding its simulation solution for DED 3D printing. (3dprint.com)
  • The anterior rim of the bony orbit, the orbital rim, is formed by orbital processes from the maxilla, zygoma, and frontal bone. (medscape.com)
  • However, appropriate image-based simulation models, which would assist the continued development of these new imaging methods are missing. (lu.se)
  • The FDA encourages medical device manufactures, simulation software developers, and academic institutions to collaborate and explore how simulation tools can be leveraged to help eliminate this public health concern. (fda.gov)
  • Mariam Mir, co-founder of startup AdditiveLab , told us about its metal AM simulation software. (3dprint.com)
  • AdditiveLab's six co-founders have over 30 years worth of experience in the AM industry between them, not to mention over 50 years worth in simulation, and its business model is to develop and distribute its software. (3dprint.com)
  • A second study, which was recently published in eLife, examined neural processing of mother's voice, a biologically salient and implicitly rewarding sound which is associated with cognitive and social development, in children with ASD. (stanford.edu)
  • First, we aim to study longitudinal development of social brain circuitry in minimally verbal children with ASD, a severely affected subpopulation that has been vastly underrepresented in the ASD literature. (stanford.edu)
  • In order to deeply study the relevance of the embedded action recognition system in collecting football training positioning data, this paper uses simulation model establishment method, data collection method, and theory and practice combination method to collect samples, analyzes the embedded action recognition system, and streamlines the algorithm. (hindawi.com)
  • Followup study on the mortality and the development of leukemia in 44 pancytopenic patients with chronic benzene exposure. (cdc.gov)
  • Fluoxetine, at the doses administered during pregnancy in this study, did not alter the morphological development of the coronal dentin-pulp complex in their offspring. (bvsalud.org)
  • By using the image intensities in the pre-operative CT scans, bone material properties could be assigned to all elements of the models. (utwente.nl)
  • Zumbrunn explained that the startup creates 3D models from CT scans, and then realigns the bone, using simulation, to the way it should look. (3dprint.com)
  • Researchers are using computer simulations to investigate how ultrasound and tiny bubbles injected into the bloodstream might break up blood clots, limiting the damage caused by a stroke in its first hours. (rdworldonline.com)
  • Using computer technology as a support when building a simulation model, the first thing you need to have is a certain computer technology because when building a simulation model, not all objects can be modeled. (hindawi.com)
  • At this time, only computer technology can be used as a support to build a simulation model of some objects and create an action recognition system that can record the position data in football training. (hindawi.com)
  • 3D Simulation: Virtual reality (VR) is an interactive computer-generated experience that takes place in a simulated environment. (labroots.com)
  • Virtual reality (VR) is a technology that immerses users in a computer-generated simulation of a 3D environment. (labroots.com)
  • Although everyone has the same basic bones and muscles, the parts aren't always connected the same way. (discovermagazine.com)
  • Measurements were carried out to evaluate the accuracy of the MCNP6 simulations and to determine the detection capabilities of the system for aluminum. (purdue.edu)
  • This is mainly due to a lack of models that describe the complex interaction between tissues within a muscle and its surroundings, e.g., muscle fibres, fascia, vasculature, bone, skin, and subcutaneous fat. (lu.se)
  • Before radiation is delivered there is a planning process called a "simulation" where the cancer and normal tissues are mapped. (medlineplus.gov)
  • Vitamin D plays an essential role in calcium homeostasis and bone health, however researches during y culturales. (udea.edu.co)
  • Adequate calcium intake can prevent bone loss. (who.int)