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  • enhancer
  • 000114841 001__ 114841 000114841 005__ 20181203021031.0 000114841 037__ $$aARTICLE 000114841 245__ $$aCharacterization of a new tissue-specific transcription factor binding to the simian virus 40 enhancer TC-II (NF-kappa B) element 000114841 269__ $$a1992 000114841 260__ $$c1992 000114841 336__ $$aJournal Articles 000114841 500__ $$aSwiss Institute for Experimental Cancer Research, Epalinges. (epfl.ch)
  • Accumulation of p300 mediates transcriptional repression of simian virus 40 enhancer in undifferentiated F9 embryonal carcinoma cells -- Ota et al. (aacrjournals.org)
  • Gene
  • Targeting the retinoblastoma protein by MC007L, gene product of the molluscum contagiosum virus: detection of a novel virus-cell interaction by a member of the poxviruses. (semanticscholar.org)
  • Membrane
  • Membrane fusion as a mechanism of simian virus 40 entry into different cellular compartments. (asm.org)
  • The hydrophobic virus binds and integrates into the ER lipid bilayer to initiate membrane penetration. (asm.org)
  • However, prior to membrane transport, the hydrophobic SV40 recruits the ER-resident Hsp70 BiP, which holds the virus in a transport-competent state until it is ready to cross the ER membrane. (asm.org)
  • Here we probed how BiP disengages from SV40 to enable the virus to penetrate the ER membrane. (asm.org)
  • When poised for membrane transport, BiP must be released from the hydrophobic SV40 so that the virus can bind to the ER membrane and initiate membrane penetration. (asm.org)
  • cellular
  • The study of DNA tumors viruses has been an extremely important tool in understanding the cellular pathways that regulate cell division and are disrupted in cancer. (bio-medicine.org)
  • Understanding the mechanisms through which these viruses interact with the cellular machinery that regulates cell division may lead to new insights into the pathways that cause cancer. (bio-medicine.org)
  • render
  • During entry, SV40 traffics to the ER, where host-induced conformational changes render the virus hydrophobic. (asm.org)
  • Type
  • It does not act synergistically in determining virus inactivation with UV light and is equally effective on wild type and a late mutant of SV40. (biomedsearch.com)
  • spread
  • Because viruses may spread more efficiently and be more pathogenic in immunocompromised individuals, we also tested for SV40 lymphoproliferative disorders that had developed in immunocompromised patients. (levelofhealth.com)
  • enable
  • Many nonenveloped viruses have evolved an infectious cycle that culminates in the lysis or permeabilization of the host to enable viral release. (umass.edu)