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  • viral
  • Khoury G., May E. Regulation of early and late simian virus 40 transcription: overproduction of early viral RNA in the absence of a functional T-antigen. (medkursor.ru)
  • The AKR murine leukemia viruses do not contain acute transforming oncogenes ( 4 ) and are thought to transform cells as a result of activating cellular proto-oncogenes in the vicinity of viral integration into chromosomal DNA ( 5 ). (jimmunol.org)
  • Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccines. (asm.org)
  • Antibodies against synthetic peptides of herpes simplex virus type 1 glycoprotein D and their capability to neutralize viral infectivity in vitro. (asm.org)
  • A C-terminal domain in the avian sarcoma-leukosis virus pol gene product is not essential for viral replication. (asm.org)
  • Relationships between H-2 and viral antigens in murine oncornavirus-induced tumors. (histrecmed.fr)
  • Nonhuman primate cells are resistant to infection by HIV-1, and studies of viral DNA formation and those involving pseudotyped viruses indicate that the block is at an early postentry step ( 17 , 18 , 33 ). (asm.org)
  • Integration of viral DNA into host DNA was first discerned for the prophage of the temperate bacteriophage lambda by Andre Lwoff in 1950 and for the simian DNA virus SV40 in cultured mammalian cells in 1968 [ 8 ]. (royalsocietypublishing.org)
  • For small DNA tumour viruses, the full replication cycle occurs via non-integrated circular viral genomes, whereas viral integration into host DNA usually leads to abortive infection and sometimes to cell transformation. (royalsocietypublishing.org)
  • Becker S., Fenyo E. M., Klein E. The «natural killer» cell in the mouse does not require H - 2 homology and is not directed against type or group - specific antigens of murine С viral proteins. (medkursor.ru)
  • Photochemical addition of the cross-linking reagent 4,5', 8-trimethylpsoralen (trioxaslen) to intracellular and viral simian virus 40 DNA-histone complexes. (asm.org)
  • Purification of virus-specific RNA from chicken cells infected with avian sarcoma virus: identification of genome-length and subgenome-leghth viral RNAs. (asm.org)
  • During virus assembly, all retroviruses specifically encapsidate two copies of full-length viral genomic RNA in the form of a non-covalently linked RNA dimer. (biomedcentral.com)
  • Thus, the main hypothesis currently being tested in clinical trials is that CTL responses can be induced safely in humans and will impact upon viral load and disease progression as they have done in primate models of simian-human immunodeficiency virus (SHIV) infection. (centrallakesclinic.biz)
  • gene
  • Lai Ching-Juh, Nathans D. The ВС gene of simian virus 40. (medkursor.ru)
  • Mapping and identification of the vaccinia virus thymidine kinase gene. (asm.org)
  • Functional mapping of Autographa california nuclear polyhedrosis virus genes required for late gene expression. (asm.org)
  • Vaccinia virus-encoded ribonucleotide reductase: sequence conservation of the gene for the small subunit and its amplification in hydroxyurea-resistant mutants. (asm.org)
  • The discovery of human gene products that are expressed in these cells and are essential for virus replication has raised the possibility that nonhuman organisms, particularly rodents, might be engineered to express these molecules, thereby rendering them able to support a productive HIV-1 replication cycle ( 8 , 20 , 26 ). (asm.org)
  • One such activity is exhibited by the product of a murine gene, Fv1 , which can confer substantial resistance to infection by murine leukemia virus (MLV) ( 15 , 24 , 28 , 30 ). (asm.org)
  • Barbacid M., Stephenson J. R., Aaronson S. A. Gag Gene of mammalian type - С RNA tumour viruses. (medkursor.ru)
  • Benjamin T. L. Tumor viruses and cellular gene expression. (medkursor.ru)
  • recombinant
  • In macaque models, vaccination with DNA plasmids or recombinant viruses bearing SIV SHIV antigenic inserts leads to significant attenuation of viremia after subsequent infection with the highly pathogenic X4-tropic hybrid isolate SHIV89.6P. Although they do not afford sterilizing immunity under any regimen tested thus far, such vaccines enable long-term suppression of viremia and prevent disease progression. (centrallakesclinic.biz)
  • characterization
  • Characterization of nerve growth factor-dependent herpes simplex virus latency in neurons in vitro. (asm.org)
  • Isolation and preliminary characterization of temperature-sensitive mutants of encephalomyocarditis virus. (asm.org)
  • Characterization of a DNA-protein complex and capsomere subunits derived from polyoma virus by treatment with ethyleneglycol-bis-N,N'-tetraacetic acid and dithiothreitol. (asm.org)
  • Biologic, serologic, and molecular characterization of several HIV-1 and HIV-2 strains has revealed their extensive heterogeneity and how viruses can evolve differently in the same individual in the immune system, bowel, and the brain. (ucsf.edu)
  • RNAs
  • The late spliced 19S and 16S RNAs of simian virus 40 can be synthesized from a common pool of transcripts. (asm.org)
  • Genetic
  • Kumar V., Eckner R. J., Bennett M. Mechanism of genetic resistance to immune suppression by friend leukemia virus: the role of marrow - dependent cells. (medkursor.ru)
  • Alizon M, Wain-Hobson S, Montagnier L, Sonigo P (1986) Genetic variability of the AIDS virus: nucleotide sequence analysis of two isolates from African patients. (springer.com)
  • Coffin JM (1986) Genetic variation in AIDS viruses. (springer.com)
  • Genetic diversity of enzootic isolates of vesicular stomatitis virus New Jersey. (asm.org)
  • tumour
  • He postulated that RNA tumour viruses made DNA copies which then integrated into host chromosomal DNA, analogous to integration of prophage in bacteria. (royalsocietypublishing.org)
  • Indeed, germ-line integration has not yet been described for DNA tumour viruses, although we now know that it occasionally occurs with human herpesvirus 6 [ 9 , 10 ]. (royalsocietypublishing.org)
  • infectivity
  • Here, we show that rodent cells exhibit differential sensitivity to infection by vesicular stomatitis virus G-pseudotyped lentiviruses and that differences between human immunodeficiency virus type 1 and simian immunodeficiency virus (SIVmac) infectivity are sometimes, but not always, governed by determinants in capsid-p2. (asm.org)
  • Levy
  • Research in the Levy laboratory is directed at understanding the interaction of viruses and the immune system in microbial pathogenesis. (ucsf.edu)
  • restriction
  • Fv1-mediated restriction of MLV infection can be overcome at high multiplicities of infection, and infection of restricting cells can give rise to multihit titration curves, implying that infection by one virus particle is facilitated by the presence of others ( 1 , 7 , 10 , 13 , 31 , 34 ). (asm.org)
  • Because of this and the fact that precisely the same saturation phenomenon that was described in the context of murine Fv1-mediated restriction is also observed in human cells ( 36 ), it is probable that humans also express an inhibitor, termed Ref1, that exhibits restriction specificity similar to that of Fv1 b . (asm.org)
  • chromosomal
  • Biegeleisen K., Rush M. G. Association of herpes simples virus type I DNA with host chromosomal DNA during productive infection. (medkursor.ru)
  • Herpes
  • Herpes simplex virus mRNA species mapping in EcoRI fragment I. (asm.org)
  • Structures of herpes simplex virus type 1 genes required for replication of virus DNA. (asm.org)
  • Mapping of functional and antigenic domains of the alpha 4 protein of herpes simplex virus 1. (asm.org)
  • Mapping early transcripts of herpes simplex virus type 1 by electron microscopy. (asm.org)
  • influenza a vir
  • An influenza a virus specific and HLA DRw8 restricted T cell clone cross reacting with a transcomplementation product of the HLA DR2 and DR4 haplotypes. (histrecmed.fr)
  • Removal of carbohydrate from influenza A virus and its hemagglutinin and the effect on biological activities. (asm.org)
  • species
  • Within a species, the viruses isolated can display considerable diversity of biological properties. (springer.com)
  • Beth E., Cikes M., Schloen L. Interspecies species- and type - specific determinants of human papovaviruses (JC and BK) and of simian virus 40. (medkursor.ru)
  • resistance
  • In addition, this report outlines several special circumstances (e.g., delayed exposure report, unknown source person, pregnancy in the exposed person, resistance of the source virus to antiretroviral agents, or toxicity of the PEP regimen) when consultation with local experts and/or the National Clinicians' Post-Exposure Prophylaxis Hotline ([PEPline] 1-888-448-4911) is advised. (cdc.gov)
  • type
  • Evolutionarily conserved epitopes on human immunodeficiency virus type 1 (HIV-1) and feline immunodeficiency virus reverse transcriptases detected by HIV-1-infected subjects. (ucsf.edu)
  • replication
  • The recognition of the importance of Rous's discovery after such a long delay was largely owing to the cell transformation assay in monolayer culture of chick embryo fibroblasts reported by Temin & Rubin [ 7 ] in 1958 which enabled quantitative experimental studies of virus replication and cell transformation. (royalsocietypublishing.org)
  • hepatitis B vir
  • This report updates and consolidates all previous U.S. Public Health Service recommendations for the management of health-care personnel (HCP) who have occupational exposure to blood and other body fluids that might contain hepatitis B virus (HBV), hepatitis C virus (HCV), or human immunodeficiency virus (HIV). (cdc.gov)
  • Avoiding occupational blood exposures is the primary way to prevent transmission of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) in health-care settings ( 1 ). (cdc.gov)
  • spleen
  • Loss of pathogenicity of spleen focus-forming virus after pseudotyping with Akv. (asm.org)