Significantly reactive oxygen ischemia time. Medical search. Frequent questions

Tourniquet release during the late period of TKR can induce ischaemic-reperfusion injury, eliciting the activation of neutrophils, circulating pro-inflammatory cytokines, and reactive oxygen species [ 2 , 3 ]. (medsci.org)
Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury (AKI). (mdpi.com)
The administration of Cordyceps sinensis extract significantly reduced focal cerebral ischemic/reperfusion injury. (biomedcentral.com)
7 The metabolism of fatty acids and glucose undergoes adaptive changes in the myocardium due to ischemia-reperfusion injury after cardiopulmonary resuscitation (CPR). (dirjournal.org)
Cryonics patients frequently experience ischemic & reperfusion injury between the time when the heart stops and cryostorage begins. (benbest.com)
PQQ powerfully protects brain cells against oxidative damage following ischemia-reperfusion injury-the inflammation and oxidative damage that result from the sudden return of blood and nutrients to tissues deprived of them by stroke. (elementnutraceuticals.com)
Over the last decade, improvements in surgical techniques, lung preservation, immunosuppression, and management of ischaemia/reperfusion injury and infections have made intermediate-term survival after lung transplantation an achievable goal. (ersjournals.com)
Over the last decade, improvements in surgical techniques, lung preservation, immunosuppression, and management of ischaemia/reperfusion injury and infections have contributed to increase the 1‐yr patient survival after lung transplantation (LTx) to 70-80% 1 . (ersjournals.com)

To provide in vivo evidence that DJ‑1 is involved in the delayed cardioprotection induced by ischemic preconditioning (IPC) against oxidative stress caused by ischemia/reperfusion (I/R), the present study subjected male Sprague‑Dawley rats to IPC (3 cycles of 5‑min coronary occlusion/5‑min reperfusion) 24 h prior to I/R (30‑min coronary occlusion/120‑min reperfusion). (spandidos-publications.com)
Myocyte-restricted Hmox1 transgenic mice exposed to MI exhibited significantly improved survival and LV function, lower interstitial fibrosis and oxidative stress. (springer.com)
Ischemia from vascular disease induces oxidative stress and injury to nerves via an increase in the production of reactive oxygen species. (medscape.com)
Activation of Sirt1 with resveratrol improved cell's resistance to oxidative stress, whereas inhibition of Sirt1 with EX527 significantly reduced cell viability after cellular oxidative stress. (frontiersin.org)
During the early stage of cerebral I/R injury, significantly-swollen mitochondria decrease adenosine triphosphate (ATP) and produce excessive reactive oxygen species (ROS) and oxidative stress, finally resulting in cell death [ 6 ]. (biomedcentral.com)
The following findings suggest that NAC could significantly protect stem cell viability and stemness during oxidative stress and exert better and prolonged effects in bioroot intragrafts. (biomedcentral.com)
Tissue necrosis caused by both oxidative stress and the inflammatory response further prevents nutrients and oxygen from reaching viable cells, which contributes to expanding the necrotic area and leads to implant failure [ 7 ]. (biomedcentral.com)
Livers treated with NMP combined with BMMSCs showed better liver function, relieved histopathological damage, reduced oxidative stress injury and ferroptosis, and the mechanism of reduction was associated with downregulation of intracellular reactive oxygen species (ROS) and free Fe²⁺ levels. (medscimonit.com)

IPC involves single or multiple brief periods of sublethal ischemia, which increase myocardial resistance to a greater subsequent insult. (spandidos-publications.com)
Conclusions: SAHA prevents I/R induced-mitochondrial dysfunction and loss, and reduces myocardial ROS production when given before or after the ischemia. (wustl.edu)
The key mechanisms underlying myocardial I/R injury include increased intracellular calcium concentration, sudden generation of reactive oxygen species (ROS) and inflammatory cytokines, adenosine triphosphate (ATP) depletion, and development of metabolic acidosis. (researchsquare.com)
Therefore, it is crucial in the clinical setting to detect myocardial metabolism conditions in real-time to evaluate the latent cardiac injury and make optimum treatment plans during the ROSC. (dirjournal.org)
In the present study, we investigated for the first time whether PEMF treatment could improve the myocardial ischaemia/reperfusion (I/R) injury and uncovered its underlying mechanisms. (pemfglobal.com)
In our study, we demonstrated for the first time that extracorporeal PEMF has a novel effect on myocardial I/R injury. (pemfglobal.com)
Tribulus terrestris L. was evaluated for its cardioprotective property against myocardial ischemia in a cell line model. (amrita.edu)

Reperfusion of ischemic areas could exacerbate ischemic brain damage through the generation of reactive oxygen species. (biomedcentral.com)

The low survival rate or dysfunction of extracellular matrix (ECM)-based engineered organs caused by the adverse effects of unfavourable local microenvironments on seed cell viability and stemness, especially the effects of excessive reactive oxygen species (ROS), prompted us to examine the importance of controlling oxidative damage for tissue transplantation and regeneration. (biomedcentral.com)

We hypothesize that SAHA protects the myocardium by maintaining mitochondrial homeostasis and reducing reactive oxygen species (ROS) production during I/R injury. (wustl.edu)

Our previous study revealed that hypoxia preconditioning of H9c2 cardiomyocytes significantly increased the de novo synthesis of DJ-1 and induced cardioprotection against prolonged hypoxic injury 24 h later ( 17 ). (spandidos-publications.com)
Persistent injury to the caudate putamen and thalamus at P1 was significantly correlated with hypertonic motor deficits in the hypoxic group. (jneurosci.org)
Antibody arrays revealed that nine proteins were significantly increased in hypoxic CM compared with normoxic CM. Furthermore, compared with vehicle and N-CM groups, the protein levels of PI3K and p‐Akt/Akt ratio in the transplanted hearts significantly increased in the H-CM group. (researchsquare.com)
Hypoxic ischemia (HI) involves multiple mechanisms, but the detailed pathogenesis is still unclear. (frontiersin.org)
Then ischemia was induced by exposing cells to ischemia buffer, in a hypoxic chamber, maintained at 0.1% O2, 95% N2 and 5% CO2, for 1 h. (amrita.edu)

After hypoxia and ischemia, the production of reactive oxygen species (ROS) rapidly accumulates and leads to mitochondrial dysfunction and delayed neuronal death. (frontiersin.org)
However, whether NRP-1 can repair mitochondrial structure and promote functional recovery after cerebral ischemia is still unknown. (biomedcentral.com)
Therefore, promoting the mitochondrial structural repair and functional recovery is the crucial for the amelioration of the neurological damage after cerebral ischemia. (biomedcentral.com)
Elevated levels of solute carrier family 14 member 1 expression induced mitochondrial reactive oxygen species accumulation, diminished the intracellular adenosine triphosphate level, and destroyed both mitochondrial membrane potential integrity and mitochondrial morphology. (biomedcentral.com)

The extract with high phenolic content (T. terrestris L. ethyl acetate extract-TTME) was further characterized for its chemical constituents and taken forward for evaluation against cardiac ischemia. (amrita.edu)

Preterm Fetal Hypoxia-Ischemia Causes Hypertonia and Motor Deficits in the Neonatal Rabbit: A Model for Human Cerebral Palsy? (jneurosci.org)
Prenatal hypoxia-ischemia to the developing brain has been strongly implicated in the subsequent development of the hypertonic motor deficits of cerebral palsy (CP) in premature and full-term infants who present with neonatal encephalopathy. (jneurosci.org)
Antenatal hypoxia-ischemia at preterm gestation results in hypertonia and abnormalities in motor control. (jneurosci.org)
These findings provide a unique behavioral model to define mechanisms and sequelae of perinatal brain injury from antenatal hypoxia-ischemia. (jneurosci.org)
Hypoxia-ischemia (H-I) is also associated with subsequent cerebral injury in a disproportionately high percentage of the survivors of premature birth ( Volpe, 2001 ). (jneurosci.org)
Most previous studies have employed models of cerebral hypoxia-ischemia in postnatal animals. (jneurosci.org)
In the present study, a new neurobehavioral battery of tests was used to characterize the motor performance of newborn pups after sustained hypoxia-ischemia to the preterm rabbit fetus at 67-70% gestation. (jneurosci.org)
Autophagy is a process that relies on lysosomal pathways for the degradation of cytoplasmic proteins and organelles and plays an important role in the pathology of brain injury such as hypoxia ischemia[ 3 ]. (ijpsonline.com)

At 24 h after stroke, NADPH-stimulated superoxide production by arteries from the infarcted core did not differ from levels generated by arteries from control rats, whereas levels were significantly lower 72 h after stroke. (gla.ac.uk)
However, at both time points after stroke, superoxide production by arteries from the ischemic penumbra was 8-fold greater than levels generated by arteries from control rats. (gla.ac.uk)
In the present work, a hypoxia/reoxygenation (H/R) model in NRK-52E cells and ischemia-reperfusion model in rats were used. (mdpi.com)
The results showed that the TFs significantly attenuated cell injury and markedly decreased serum creatinine (Cr) and blood urea nitrogen (BUN) levels in rats. (mdpi.com)
Cordyceps sinensis extract significantly improved the outcome in rats after cerebral ischemia and reperfusion in terms of neurobehavioral function. (biomedcentral.com)
Ischemia was induced by permanent occlusion of the middle cerebral artery in rats, via surgical insertion of a nylon filament into the internal carotid artery. (biomedcentral.com)

The cascade of events leading to neuronal injury and death in ischemia includes the release of cytokines and free radicals, and induction of inflammation, apoptosis, and excitotoxicity [ 1 ]. (biomedcentral.com)
This "cytokine storm" plays a decisive role in COVID-19, causing excessive liberation of interleukin-6, Interleukin-1 and TNFα among other inflammatory cytokines which are reflected in increased plasma reactive C protein and leukocytosis. (scientificarchives.com)
Cytokines also profoundly affects platelets and coagulation/fibrinolytic systems causing thrombosis, bleeding and severe limb ischemia. (scientificarchives.com)

These findings suggested that MQ exerts a neuroprotective effect in cerebral ischemia by blocking apoptosis via the p-JNK/Bax pathway. (archive.org)
Rutin has demonstrated the neuroprotective effect on brain ischemia. (fuqna.com)

Flow cytometry assessed the apoptosis rates and the levels of reactive oxygen species. (archive.org)

Reactive oxygen species play a role in neuronal damage following cerebral ischemia-reperfusion. (gla.ac.uk)
The improved motor recovery in Hv1 -/- mice was associated with decreased interleukin-1β, reactive oxygen/ nitrogen species production and reduced neuronal loss. (researchsquare.com)
Lentivirus (LV)-NRP-1 was transfected into rat primary cortical neuronal cultures before a 2-h oxygen-glucose deprivation and reoxygenation (OGD/R) injury to neurons. (biomedcentral.com)

Both in vitro and in vivo models of cerebral ischemia/reperfusion (I/R) injury presented a sharp increase in NRP-1 expression. (biomedcentral.com)

Thus, development of strategies targeting particular subsets of inflammatory cells and providing well-timed resolution of inflammation may be crucial for proper healing and recovery. (springer.com)
Vi postulerer, at senescens af mesenkymale stamceller (MSC), multipotente celler med pro-angiogene aktiviteter, er en af de mekanismer, hvormed systemisk inflammation udøver hæmmende effekter på angiogenese i præeklampsi. (biomedicalhouse.com)
In addition, Hyperbaric Oxygen Therapy can also remarkably reduce inflammation in the body as a whole. (vibratrim.net)

However, whether the increase in DJ-1 expression mediates protection against ischemia/reperfusion (I/R) injury in vivo during the late phase of IPC remains to be determined. (spandidos-publications.com)
Uterine ischemia in the dams resulted in a distinct neurobehavioral phenotype in the newborn pups, which was characterized by an increase in forelimb tone that was significantly correlated with histological evidence of persistent injury to subcortical motor pathways involving the basal ganglia and anterior thalamus. (jneurosci.org)
Short-term cardiac stress, induced by ischemia-reperfusion (I/R) injury resulted in impaired left ventricular (LV) recovery and increased infarct size in heterozygous Hmox1-deficient (Hmox1 +/− ) mice [ 55 ]. (springer.com)
Aims: The FDA-approved histone deacetylase (HDAC) inhibitor, suberoylanilide hydroxamic acid (SAHA, Vorinostat) has been shown to induce cardiomyocyte autophagy and blunt ischemia/reperfusion (I/R) injury when administered at the time of reperfusion. (wustl.edu)
In heart transplantation, donor hearts inevitably suffer from ischemia/reperfusion (I/R) injury, which leads to primary graft dysfunction and affects patients' survival rate. (researchsquare.com)
Previous studies have shown that ischemia/reperfusion (I/R) injury acts as a significant role in PGD(4), contributing to adverse short- and long-term clinical outcomes in the recipients. (researchsquare.com)
Cardiopulmonary bypass (CPB) causes systemic inflammatory response and ischemia-reperfusion (IR) injury. (hindawi.com)
However, CPB inevitably causes systemic inflammatory response and ischemia-reperfusion (IR) injury, which can negatively affect postoperative cardiac function and a patient's long-term prognosis [ 1 ]. (hindawi.com)
The in vivo results showed that per-treatment of PEMF could significantly improve the cardiac function in I/R injury group. (pemfglobal.com)
Previous studies suggest that the cyclooxygenase-2 (COX-2) inhibitor nimesulide has a remarkable protective effect against different types of brain injury including ischemia. (biomedcentral.com)

Mitochondria, a powerhouse of the cell, are rich in a large number of enzymes, which not only participate in cellular oxidative phosphorylation and ATP synthesis, but also regulate intracellular calcium ions and reactive oxygen species to maintain cellular homeostasis. (biomedcentral.com)

These data show that nimesulide protects against permanent focal cerebral ischemia, even with a 2 h post-treatment delay. (biomedcentral.com)

Lactate dehydrogenase (LDH) and creatine kinase‑MB (CK‑MB) release, infarct size, cardiac function, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) activities, malondialdehyde (MDA), intracellular reactive oxygen species (ROS), and DJ‑1 protein expression levels were assessed. (spandidos-publications.com)
Real-time PCR was used to evaluate the mRNA expression levels, and Western blotting was used to analyze the changes in protein levels of p-JNK, Bax, cleaved Caspase3. (archive.org)
Compared to the oxygen-glucose deprivation/reperfusion group, the protein and mRNA expressions of p-JNK, Bax, cleaved Caspase3 was decreased significantly. (archive.org)
BMMSCs also significantly improved the expression level of microtubule-associated protein 1 light chain 3 (LC3)-II in both DCD donor livers and ROS-induced injured IAR-20 cells, including upregulating the expression of ferritin. (medscimonit.com)
C- reactive protein (CRP), which measures the overall inflammatory response in the body, is a common marker for cancer. (vibratrim.net)

Our study shows that the expression of Sirt1 was downregulated after oxygen-glucose deprivation. (frontiersin.org)
The goal of this study was to explore the regulatory mechanism of trehalose on the autophagy death of SHSY5Y cells induced by oxygen and sugar deprivation from the aspect of glycolysis. (ijpsonline.com)
Human SH-SY5Y cells were divided into three groups includes control group (control), model group (oxygen and sugar deprivation) and experimental group (oxygen and sugar deprivation+trehalose). (ijpsonline.com)
Trehalose can reduce the damage of SH-SY5Y cells caused by oxygen and sugar deprivation. (ijpsonline.com)
The symptoms of brain ischemia reflect the anatomical region undergoing blood and oxygen deprivation. (wikipedia.org)
Further, irregular heartbeats may result in formation of blood clots, thus leading to oxygen deprivation to all organs. (wikipedia.org)

Ischaemic preconditioning describes the phenomenon where transient and brief ischaemia confers protection against a subsequent prolonged and injurious period of ischaemia. (medsci.org)
Conclusions This research displays the correlation between your time and energy to significant LVOT incline decline subsequent septal perforator balloon stoppage along with the degree of ultimate slope reaction right after ASA. (gp120inhibitor.com)

At the same time, supplementation of Cordyceps sinensis extract significantly boosted the defense mechanism against cerebral ischemia by increasing antioxidants activity related to lesion pathogenesis. (biomedcentral.com)
The defense mechanism against cerebral ischemia was by increasing antioxidants activity related to lesion pathogenesis. (biomedcentral.com)

Reactive nitrogen species (RNS), like reactive oxygen species, impose severe stresses on damaged neurons. (elementnutraceuticals.com)

Ischemia and reperfusion can cause serious brain damage in stroke or cardiac arrest. (benbest.com)
Given immediately before induction of stroke in animal models, PQQ significantly reduces the size of the damaged brain area. (elementnutraceuticals.com)
This leads to poor oxygen supply or cerebral hypoxia and thus leads to the death of brain tissue or cerebral infarction/ischemic stroke. (wikipedia.org)
Other effects that may result from brain ischemia are stroke, cardiorespiratory arrest, and irreversible brain damage. (wikipedia.org)
citation needed] Other pathological events that may result in brain ischemia include cardiorespiratory arrest, stroke, and severe irreversible brain damage. (wikipedia.org)

However, it is not easy to apply ischaemic preconditioning in a clinical setting because brief organ ischaemia should be preceded after real ischaemic time [ 8 ]. (medsci.org)
The application of RIPC into clinical fields is more useful than ischaemic preconditioning because it is easy to apply briefly preceding ischaemia to distant organs such as the limbs. (medsci.org)
These data reveal that nursing based on oxygen administration can improve the clinical efficacy of renal cell carcinoma therapies, being safe and effective. (biomedcentral.com)
The treatment for renal parenchymal tumors has changed over time, and this trend continues today as a result of technological progress made with clinical research and improved diagnostic and therapeutic tools. (biomedcentral.com)

However, it is now generally accepted that the mammalian brain may be more resistant to ischemia than previously thought. (biomedcentral.com)
In 1974, Hossmann and Zimmermann demonstrated that ischemia induced in mammalian brains for up to an hour can be at least partially recovered. (wikipedia.org)

This orbital compression will result in ophthalmic and central retinal artery occlusion which lead to ischemia in the inner retina and the patient may experience sudden unilateral blindness and eye pain. (wikipedia.org)

The authors found that the aerobic oxidation of glucose was reduced, and the anaerobic glycolysis was significantly enhanced in the myocardium in the early stage of CPR. (dirjournal.org)

Ischemia leads to alterations in brain metabolism, reduction in metabolic rates, and energy crisis. (wikipedia.org)
A way that Hyperbaric Oxygen Therapy Chamber can affect cancer cells is through a reduction in hypoxia, a low-oxygen condition that is common in cancerous tumors. (vibratrim.net)

Methods and final results: Fasted Sprague-Dawley test subjects were gavaged with some other concentrations regarding green tea leaf (GTE) 2 before Three months minutes involving comfortable ischemia from the quit lateral lean meats lobe (30% of liver organ). (gp120inhibitor.com)

Meanwhile, the organ protective effect of ischaemic preconditioning could be induced when the episodic ischaemia is at distant tissues or organs, the concept being termed remote ischaemic preconditioning (RIPC) [ 9 ]. (medsci.org)
Ischemia is the condition suffered by tissues & organs when deprived of blood flow -- mostly the effects of inadequate nutrient & oxygen. (benbest.com)

Furthermore, the tourniquet could help reduce the operation time. (biomedcentral.com)
reported that the use of a tourniquet in TKA resulted in a much shorter operation time[ 3 ]. (biomedcentral.com)

Thus, the activity of NADPH-oxidase is enhanced in cerebral arteries from the ischemic penumbra at 24 h and 72 h following cerebral ischemia. (gla.ac.uk)
Additionally, NADPH-oxidase activity is temporarily enhanced after cerebral ischemia within arteries from non-ischemic parts of the brain. (gla.ac.uk)
Ischemia within the arteries branching from the internal carotid artery may result in symptoms such as blindness in one eye, weakness in one arm or leg, or weakness in one entire side of the body. (wikipedia.org)
Ischemia within the arteries branching from the vertebral arteries in the back of the brain may result in symptoms such as dizziness, vertigo, double vision, or weakness on both sides of the body[citation needed]. (wikipedia.org)
Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population. (wikipedia.org)
citation needed] Compression of blood vessels may also lead to brain ischemia, by blocking the arteries that carry oxygen to the brain. (wikipedia.org)
citation needed] Blockage of arteries due to plaque buildup may also result in ischemia. (wikipedia.org)

A total of 64 patients with renal cell carcinoma were divided into the observation group (nursing based on oxygen administration) and the control group (conventional nursing). (biomedcentral.com)
Nursing based on oxygen administration decreased the value of renal function indexes, serum inflammatory factors, and tumor markers in renal cell carcinoma patients. (biomedcentral.com)

The increase in intracellular cGMP and calcium level results in the production of reactive oxygen species (ROS) which damage macular cone cells and leading to macular degeneration. (wikipedia.org)
Another ATP-driven pump helps keep extracellular calcium ions (Ca 2+ ) 10,000 times more concentrated than within the cytoplasm. (benbest.com)
In times of high metabolic demand and adequate availability of oxygen, elevated calcium in mitochondria can increase ATP production by stimulation of three enzymes in the Krebs citric acid cycle: pyruvate dehydrogenase, alpha-ketoglutarate and isocitrate dehydrogenase. (benbest.com)

Further, HEE treatment during training significantly reduced the markers of tissue damage. (biomedcentral.com)
and global ischemia, which encompasses wide areas of brain tissue. (wikipedia.org)
Hyperbaric oxygen (HBO) treatment has for centuries been used to improve or cure disorders involving hypoxia and ischemia, by enhancing the amount of dissolved oxygen in the plasma and thereby increasing O2 delivery to the tissue. (vibratrim.net)

Further, symptoms can last from a few seconds to a few minutes or extended periods of time. (wikipedia.org)

Thus, we hypothesize that Cordyceps sinensis possess protective effect of against ischemia-induced brain infarction by modulating 17β-estradiol production. (biomedcentral.com)
Brain ischemia is a condition in which there is insufficient bloodflow to the brain to meet metabolic demand. (wikipedia.org)
The main symptoms of brain ischemia involve impairments in vision, body movement, and speaking. (wikipedia.org)
The causes of brain ischemia vary from sickle cell anemia to congenital heart defects. (wikipedia.org)
Symptoms of brain ischemia can include unconsciousness, blindness, problems with coordination, and weakness in the body. (wikipedia.org)
Accordingly, this discovery raised the possibility of intervening after brain ischemia before the damage becomes irreversible. (wikipedia.org)
The symptoms of brain ischemia range from mild to severe. (wikipedia.org)
Similar to cerebral hypoxia, severe or prolonged brain ischemia will result in unconsciousness, brain damage or death, mediated by the ischemic cascade. (wikipedia.org)
Brain ischemia has been linked to a variety of diseases or abnormalities. (wikipedia.org)
Sickle cell anemia may cause brain ischemia associated with the irregularly shaped blood cells. (wikipedia.org)
citation needed] A heart attack can also cause brain ischemia due to the correlation that exists between heart attack and low blood pressure. (wikipedia.org)
Therefore, brain ischemia can result from events other than heart attacks. (wikipedia.org)
citation needed] Congenital heart defects may also cause brain ischemia due to the lack of appropriate artery formation and connection. (wikipedia.org)

Conclusion: Preconditioning which has a individual mouth dosage involving GTE ameliorates ischemia-reperfusion damage in liver. (gp120inhibitor.com)
These leukocytes produce oxygen-derived free radicals that can directly damage graft cells via cell membrane damage. (biomedcentral.com)

It provides direct protection against hypoxia by its anti-apoptotic, anti-oxidative, and anti-inflammatory properties and for its angiogenic capacity that allows the oxygen supply to ischemic tissues. (molvis.org)

Additionally, earlier studies in 2009 and 2007 discovered that those conventional cancer patients who utilized Hyperbaric Oxygen Therapy as well have longer survival times and deal with fewer side effects. (vibratrim.net)

After heart transplantation, the donor heart preservation with normoxic CM was associated with shorter re-beating time, histopathological scores, and left ventricular systolic diameter, higher ejection fraction, and fractional shortening of transplanted hearts. (researchsquare.com)

Most of the energy (ATP) generated in the mitochondria requires oxygen, but in the absence of oxygen some energy can be generated in the cytoplasm outside of the mitochondria by glycolysis , wherein a glucose molecule produces two molecules of ATP and lactate. (benbest.com)

However, oxygen therapy might cause the accumulation of distal bronchial viscous secretions because of positive pressure ventilation mode, and thus increase airway resistance, aggravate systemic hypoxia [15]. (researchgate.net)

MSCs significantly reversed the imbalance of glycolysis in sperm and testis induced by testicular torsion-detorsion, as evidenced by increasing the expression of phosphoglycerate kinase 2 and glyceraldehyde-3-phosphate dehydrogenase-spermatogenic, activating Akt, and increasing glycogen synthase kinase 3 (GSK3), which led to the increase in glycolysis cascades and ATP production. (biomedcentral.com)
Breathing in 100% oxygen in a high pressure environment can help stimulate healing on all levels by promoting the production of therapeutic chemicals in the body. (vibratrim.net)

The Ca 2+ -related activation of intracellular second messenger systems, the increase in reactive oxygen species formation, as well as hypoxia itself triggers the expression of a large number of pro-inflammatory genes following cerebral ischemia. (biomedcentral.com)

The lower doses failed to significantly reduce infarction but showed a beneficial effect on neurological function. (biomedcentral.com)

In vitro studies demonstrated that MQ enhanced the cell survival rates and decreased the levels of reactive oxygen species. (archive.org)
The sCA-125 levels were significantly higher in noncancer patients than those in the cancer patients, while the pCA-125 levels showed no significant difference between the two groups. (go.jp)
According to experts, time spent in a Hyperbaric Oxygen Therapy Chambe r can drastically elevate oxygen levels in the blood stream. (vibratrim.net)
Furthermore, high levels of oxygen can also promote the growth of new blood vessels. (vibratrim.net)

Following 90min involving warm ischemia aminotransferase (AST), alanine aminotransferase (T), and also lactate dehydrogenase (LDH) improved substantially to 1946 +/- 272/3244 +/- 757 U/L, 1680 +/- 134/2080 +/- 379 U/L, along with 7857 +/- 1851/2036 +/- 1193 U/L from 2/6 , respectively. (gp120inhibitor.com)

In the early stage of ischemia and hypoxia, cells will increase the energy supply to the ischemic area, especially the functional area of the ischemic penumbra, by regulating glycolysis. (ijpsonline.com)

Significantly lower incidence of left ventricle (LV) free wall rupture was noted between 3rd and 5th day after MI in Hmox1 −/− mice resulting in their better overall survival. (springer.com)
Splenectomy decreased the numbers of circulating inflammatory Ly6C hi monocytes in blood, reduced the numbers of proinflammatory cardiac macrophages and significantly improved the post-MI LV function in Hmox1 −/− mice. (springer.com)
CNS and behavioral activity of rutin were on hole board, thiopental-induced sleeping time and locomotor activity tests in mice. (fuqna.com)

From the point of view of "self-medication" or "preventive medicine," Cordyceps sinensis was used in the prevention of cerebral ischemia in this paper. (biomedcentral.com)
These experimental results suggest that complement Cordyceps sinensis extract is protective after cerebral ischemia in specific way. (biomedcentral.com)
J 'm Coll Cardiol Intv Next year;Four:1030-4) (Chemical) Next year by the National University involving Cardiology BasisRange: Polyphenolic elements involving green tea (Camellia sinensis) have been shown to be powerful scavengers of reactive oxygen kinds (ROS). (gp120inhibitor.com)

Even though oxygen is necessary for cellular survival, a high percentage of air in normal atmosphere is made up of only about 21% oxygen. (vibratrim.net)

The time between transplantation and onset of BOS can range from a few months to several years, but in most series, the median time to diagnosis is 16-20 months. (ersjournals.com)

Anatomy29

Organisms10

Diseases30

Chemicals and Drugs82

Analytical, Diagnostic and Therapeutic Techniques and Equipment58

Phenomena and Processes42

Disciplines and Occupations2

Technology, Industry, Agriculture1

Information Science2

Named Groups2

Health Care18

Reperfusion injury8

Oxidative stress8

Myocardial7

Generation of reactive oxygen1

Excessive reactive oxygen1

Reducing reactive oxygen1

Hypoxic5

Mitochondrial4

Cardiac ischemia1

Hypoxia-ischemia8

Rats6

Cytokines3

Neuroprotective effect2

Apoptosis1

Neuronal3

Models of cerebral1

Inflammation3

Injury10

Intracellular calcium1

Focal1

Protein5

Deprivation6

Subsequent2

Pathogenesis2

Nitrogen species1

Stroke5

Clinical4

Mammalian2

Occlusion1

Myocardium1

Reduction2

Methods1

Organs2

Tourniquet2

Arteries7

Renal2

Calcium3

Tissue3

Periods1

Brain13

Damage2

Tissues1

Additionally1

Left ventricular1

Mitochondria1

Accumulation1

Production2

Genes1

Neurological1

Levels4

Lactate1

Penumbra1

Mice3

Sinensis3

Survival1

Onset1