The enzyme sialate O-acetylesterase (EC 3.1.1.53) catalyzes the reaction N-acetyl-O-acetylneuraminate + H2O = N-acetylneuraminate + acetate In human it is encoded by the SIAE gene located on chromosome 11. (wikipedia.org)
Human Sialic acid O-acetyl esterase (SIAE) - mediated changes in sensitivity to etoposide in a medulloblastoma cell line. (open.ac.uk)
Amino acids2
While all coronaviruses contains these proteins, a subset (HEV, HCV-OC43 and BCV) is now recognized to possess an additional glycopolypeptide (gp65), which is unrelated to S or M. N protein The number of amino acids in the N protein has been determined by cloning and sequencing for MHV strains A59 (Armstrong et al. (pdfroom.com)
The conserved space positive by the neutralizing antibody is a peptide of roughly 12 amino acids in dimension and ideally 8-10 amino acids. (kits-elisa.com)
Terminal1
α(2-3,6,8,9) Sialidase Au cleaves all cleaves all non-reducing terminal sialic acid residues from complex carbohydrates and glycoproteins. (ludger.com)
Glycoproteins1
The sialyltransferase ST6GAL1 that adds α2-6 linked sialic acids to N-glycans of cell surface and secreted glycoproteins is prominently associated with many human cancers. (nature.com)
Antibody1
The present invention is extra directed to a package deal and a means for detecting the presence and determining focus of an antibody that inhibits HIV-1 fusion-associated epitope, a peptide on gp41 with the amino acid sequence represented by GCSGKLIC. (kits-elisa.com)
Enzyme1
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. (nih.gov)
Sialidase2
Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9(4)-O-acetylesterase, and sialidase. (wikipedia.org)
To also make O-acetylated sialyl residues susceptible to the action of its sialidase and sialic acid uptake system, Tannerella produces NanS, an O-acetylesterase with two putative catalytic domains. (bvsalud.org)
Homo1
LOCUS BC068450 2914 bp mRNA linear HUM 17-JUL-2006 DEFINITION Homo sapiens sialic acid acetylesterase, mRNA (cDNA clone MGC:87009 IMAGE:5278370), complete cds. (nig.ac.jp)
Lectins1
15. Sensing the neuronal glycocalyx by glial sialic acid binding immunoglobulin-like lectins. (nih.gov)
Uptake1
5. Exploring the Impact of Ketodeoxynonulosonic Acid in Host-Pathogen Interactions Using Uptake and Surface Display by Nontypeable Haemophilus influenzae. (nih.gov)
Influenza2
Moreover, bovine coronavirus exhibits an acetylesterase activity in vitro using bovine submaxillary mucin as substrate similar to the enzymatic activity found in influenza C viruses. (mssm.edu)
These results suggest that, like influenza C viruses, human coronavirus OC43 and bovine coronavirus recognize O-acetylated sialic acid or a similar derivative as cell receptor. (mssm.edu)
Genes1
Based on the transcriptional profiles generated by reverse transcriptase PCR, the sgu locus can be classified into at least three regulatory units: 1) sialic acid- or sialo oligosaccharide -inducible genes, 2) constitutively expressed genes that can be down-regulated by catabolite repression, and 3) constitutively expressed genes. (unl.edu)