• Previously, acute graft versus host disease (GVHD) required symptoms within the first 100 days of transplantation and chronic GVHD after day 100. (medscape.com)
  • establish a convolutional neural network-based model to predict acute graft-versus-host disease (aGVHD) after allogeneic hematopoietic stem cell transplantation. (nature.com)
  • Graft versus host disease (GVHD), a severe immunogenic complication of allogeneic hematopoietic stem cell transplantation (HSCT), represents the most frequent cause of transplant-related mortality (TRM). (hindawi.com)
  • Intestinal aGvHD can occur after stem cell transplantation when the immune cells of the donor (the graft) consider the recipient's body (the host) as foreign and attack the organs and tissue. (businesswire.com)
  • An acute graft-versus-host disease activity index to predict survival after hematopoietic cell transplantation with myeloablative conditioning regimens. (nature.com)
  • Prospective evaluation for upper gastrointestinal tract acute graft-versus-host disease after hematopoietic stem cell transplantation. (nature.com)
  • Developed for decision-makers, this Graft vs. Host Disease - Epidemiology Forecast - 2032 report provides a detailed panorama on the incidence and prevalence of this severe complication of allogeneic stem cell transplantation in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. (researchandmarkets.com)
  • Graft-versus-host disease is a potentially serious complication of allogeneic stem cell transplantation. (researchandmarkets.com)
  • Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality after allogeneic stem cell transplantation. (nih.gov)
  • Scholars@Duke publication: Novel Scoring Criteria for the Evaluation of Ocular Graft-versus-Host Disease in a Preclinical Allogeneic Hematopoietic Stem Cell Transplantation Animal Model. (duke.edu)
  • Ocular complications occur after transplantation in 60% to 90% of chronic graft-versus-host disease (GVHD) patients and significantly impair vision-related quality of life. (duke.edu)
  • Preliminary human and animal studies indicate that AAT may considerably reduce the severity of GVHD, which is one of the key, life threatening complications of allogeneic stem cell transplantation. (kamada.com)
  • The relationship between the oral and gut microbiome of pediatric patients with hematologic disorders and Graft-versus-Host Disease (GVHD) after transplantation. (who.int)
  • Approximately one-third of children with acute myeloid leukemia (AML) experience disease relapse despite risk-adapted intensive multiagent chemotherapy with or without hematopoietic cell transplantation (HCT) [ 1 ]. (biomedcentral.com)
  • The first evidence for the therapeutic effectiveness of natural killer (NK) cells in AML was established in a study of 57 adult patients, in which none of the 20 individuals who received haploidentical cell transplantation from a killer immunoglobulin-like receptor (KIR)-human leukocyte antigen (HLA)-mismatched donor experienced disease relapse [ 2 ]. (biomedcentral.com)
  • Approximately 30-70% of patients who have undergone allogeneic (allo) hematopoietic stem cell transplantation (HSCT) eventually experience chronic graft-versus-host disease (cGVHD). (biomedcentral.com)
  • Pediatric allogeneic hematopoietic stem cell transplantation (AHSCT) recipients with chronic graft-versus-host disease (cGVHD) are at high risk for endocrinopathies, particularly impaired bone mineral density (BMD). (qxmd.com)
  • GVHD prophylaxis Graft versus host disease (GVHD) is one of the major causes of death in patients undergoing allogeneic hematopoietic cell transplantation. (web.app)
  • African Americans and Caucasians were matched for age, donor-recipient HLA match, graft type and transplantation year. (aamds.org)
  • For the purposes of this document, HSCT is defined of the CDC, the Infectious Diseases Society of America, as any transplantation of blood or marrow-derived he- and the American Society of Blood and Marrow Trans- matopoietic stem cells, regardless of transplant type plantation," which was published in the Morbidity and (allogeneic or autologous) or cell source (bone marrow, Mortality Weekly Report [1]. (cdc.gov)
  • Transplant infectious disease : an official journal of the Transplantation Society 2022 6 24 (4): e13879. (cdc.gov)
  • Boy who developed stage 3 skin involvement with acute graft versus host disease (GVHD) despite receiving prophylaxis with cyclosporin A. The donor was a sister matched for human leukocyte antigen. (medscape.com)
  • Shortly before graft infusion, GVHD prophylaxis (immunosuppression) is started. (hindawi.com)
  • At the Aflac Cancer and Blood Disorders Center, we provide long-term, specialized care to children and teens who have been diagnosed with chronic graft-versus-host disease (GVHD) as a result of a blood and marrow transplant (BMT). (choa.org)
  • Chronic graft-versus-host disease (GVHD) can occur in children who have received a BMT for their cancer or blood disorder diagnosis. (choa.org)
  • [6] Chronic graft-versus-host disease also attacks the above organs, but over its long-term course can also cause damage to the connective tissue and exocrine glands . (wikipedia.org)
  • Graft-versus-host disease is categorized into two types: acute and chronic graft-versus-host disease. (researchandmarkets.com)
  • Furthermore, in the 7MM, the 5-year prevalence of chronic graft-versus-host disease was ~23,080 in 2022, which is likely to increase to ~26,300 cases by 2032. (researchandmarkets.com)
  • The overall severity of chronic graft-versus-host disease is classified as mild, moderate, or severe based on organ-specific grading (number of organs and severity). (researchandmarkets.com)
  • Approximately ~45% of 5-year prevalent cases of chronic graft-versus-host disease belong to the moderate category. (researchandmarkets.com)
  • Skin (~59%), oral mucosa (~53%), eyes (~53%), lungs (~43%), liver (~29%), joints and fascia (~28%), and gastrointestinal (~23%) are the most often affected organs by chronic graft-versus-host disease. (researchandmarkets.com)
  • The two main types of Graft vs. Host Disease are acute Graft vs. Host Disease and Chronic Graft vs. Host Disease. (researchandmarkets.com)
  • Data on the impact of chronic Graft-versus-host disease (cGvHD) on cognitive function (CF) and quality of life (QoL) of long-term transplant survivors are sparse. (biomedcentral.com)
  • The influence of total body irradiation (TBI) as part of the conditioning regimen and chronic graft-versus-host disease (cGvHD) on cognitive function (CF) and quality of life (QoL) of very long-term survivors is still unclear. (biomedcentral.com)
  • Impaired Bone Mineral Density in Pediatric Patients with Chronic Graft-versus-Host Disease. (qxmd.com)
  • We report 33 patients with cGVHD who were referred to the National Institutes of Health (NIH) for the Natural History of Clinical and Biological Factors Determining Outcomes in Chronic Graft-versus-Host Disease Study (NCT 0092235) and underwent formal BMD assessment via dual-energy X-ray absorptiometry (DEXA). (qxmd.com)
  • A randomized, placebo-controlled trial of oral beclomethasone dipropionate as a prednisone-sparing therapy for gastrointestinal graft-versus-host disease. (nature.com)
  • MCW Cancer Center scientists identify new therapy to reduce the severity of gastrointestinal graft versus host disease and improve patient outcomes. (mcw.edu)
  • The intensity of the conditioning regimen correlates with the incidence and severity of OM, but no studies have analyzed this relationship among various conditioning regimens. (elsevierpure.com)
  • Correlate incidence and severity of graft-versus-host disease with relapse and survival in patients treated with this regimen. (bioseek.eu)
  • May 30, 2015 We hypothesized that CBD may decrease GVHD incidence and severity after alloHCT. (web.app)
  • The day-100 cumulative incidence of grade III-IV, but not grade II-IV acute graft versus host disease (GVHD) was higher in African Americans compared to Caucasians (29% vs. 13%, p=0.006). (aamds.org)
  • Though the 5-year cumulative incidence of chronic GVHD was not significantly different between the racial groups, African Americans were more likely to have extensive chronic GVHD compared to Caucasians (72% vs. 49%, p=0.06). (aamds.org)
  • [ 4 ] They found that the incidence of severe mucositis (WHO grades 3 and 4) was no higher than 10% (and in most cases much lower) in any of the disease groups. (medscape.com)
  • In allogeneic HSCT, donor T cells target malignant hematopoietic cell populations, creating a graft-versus-tumor effect. (medscape.com)
  • Low-dose post-transplant cyclophosphamide (PTCy) in conjunction with anti-thymocyte globulin (ATG) appears as a potentially effective graft-versus-host disease (GVHD) prevention strategy in haploidentical hematopoietic cell transplant (haplo-HCT). (biomedcentral.com)
  • Graft-versus-host disease is a potentially serious complication in a recipient of an allograft (usually a haematopoietic stem cell transplant) that arises from the attack of recipient tissues (such as the skin, liver or gut) by donor-derived T cells. (nature.com)
  • While recovering from a blood and marrow transplant (BMT), this sickle cell disease patient discovered a love of cooking. (choa.org)
  • The acute or fulminant form of the disease (aGvHD) is normally observed within the first 10 to 100 days post-transplant, [9] [10] and is a major challenge to transplants owing to associated morbidity and mortality. (wikipedia.org)
  • Total allogenic transplant cases of graft-versus-host disease in the 7MM range from ~24,440 in 2022 to ~29,600 in 2032. (researchandmarkets.com)
  • the disease is a side effect that is common after an allogeneic bone marrow transplant. (researchandmarkets.com)
  • As an allogeneic transplant recipient, the patient might experience either form of Graft vs. Host Disease, either form, or neither. (researchandmarkets.com)
  • Graft-versus-host disease (GVHD) is the leading cause of complications after an allogeneic stem cell transplant. (uchicagomedicine.org)
  • Prior allogeneic hematopoietic stem cell transplant (HSCT) or donor lymphocyte infusion within 6 months prior to enrollment, current acute graft versus host disease grade 2-4 by Glucksberg criteria or severity B-D by by International Bone Marrow Transplant Registry (IBMTR) index or history of severe (grade 3-4) acute graft versus host disease. (moffitt.org)
  • Graft-versus-host disease (GVHD) is a frequent complication after a stem cell transplant using donor cells. (bmtinfonet.org)
  • Given the severity, the doctors advised an immediate stem cell transplant. (parentsguidecordblood.org)
  • In the absence of a suitable family donor, stem cells from a closely matching unrelated donor are the fallback transplant strategy to ensure lower rates of complications such as graft versus host disease 1 . (parentsguidecordblood.org)
  • But this doesn't guarantee that the transplant itself will succeed in treating the original disease. (medlineplus.gov)
  • Graft versus host disease occurs as a result of stem cell transplant rejection. (web.app)
  • The drug of choice for prevention of CMV disease in solid-organ transplant patients is valganciclovir. (medscape.com)
  • Graft-versus-host disease ( GvHD ) is a syndrome , characterized by inflammation in different organs. (wikipedia.org)
  • Newer research indicates that other graft-versus-host disease target organs include the immune system (the hematopoietic system , e.g., the bone marrow and the thymus ) itself, and the lungs in the form of immune-mediated pneumonitis . (wikipedia.org)
  • An assessment of the degree of involvement of these organs determines the severity of acute graft-versus-host disease. (researchandmarkets.com)
  • Learn who's at risk for developing graft-versus-host disease (GVHD), how it affects organs and tissues, treatment options and steps you can take to minimize the risk and severity of GVHD. (bmtinfonet.org)
  • Acute GVHD usually starts as scattered erythematous macules and papules that involve a greater percentage of total body surface area as the severity of GVHD increases. (medscape.com)
  • Acute GVHD severity grading is based on target organ assessments. (nature.com)
  • Our data suggest some of the observed survival differences between Caucasians and African Americans may be explained by higher rates of acute GVHD and severity of chronic GVHD. (aamds.org)
  • Patients who develop steroid-refractory (SR)-cGVHD are the most severely impacted due to significant disease and financial burden. (biomedcentral.com)
  • Ocular surface inflammation and dry eye disease are the most common manifestations of ocular GVHD. (duke.edu)
  • Ocular GVHD can be viewed as an excellent preclinical model that can be studied to understand the immune pathogenesis of this common and debilitating disease. (duke.edu)
  • Ocular Graft Versus-host Disease Patients Exhibit Impaired Corneal Biomechanics. (arvojournals.org)
  • Increased levels of tear matrix metalloproteinase-9 (MMP-9) have been detected in ocular graft versus host disease (oGVHD) patients. (arvojournals.org)
  • In 2022, the 7MM mortality-adjusted treated acute graft-versus-host disease patients were ~9,830 in first-line, and these cases are expected to increase to ~11,740 cases by 2032. (researchandmarkets.com)
  • Graft-versus-host disease (GVHD) is a complication that occurs following allo-HSCT and is a major driver of posttransplant morbidity and mortality [ 2 ]. (biomedcentral.com)
  • Aggressive resuscitation, nutritional support, thorough surgical excision of infected wounds, early wound closure, grafting and the development of effective topical and systemic chemotherapy have largely improved morbidity and mortality rates of burn patients. (who.int)
  • Graft versus host disease (GVHD) pathophysiology is a complex interplay between cells that comprise the adaptive and innate arms of the immune system. (cannabisclinicians.org)
  • OSAKA, Japan & CAMBRIDGE, Mass.--( BUSINESS WIRE )--Takeda ( TSE:4502/NYSE:TAK ) today announced late-breaking data from the Phase 3 GRAPHITE study presented at the 2023 Tandem Meetings, demonstrating vedolizumab achieved a statistically significant and clinically meaningful improvement in lower gastrointestinal (GI) aGvHD-free survival by Day 180 after allo-HSCT with no relevant differences in safety profile versus placebo. (businesswire.com)
  • Opportunistic infections (OIs) are defined as any in- the infusion of hematopoietic stem cells from a donor fections that occur with increased frequency or severity into a patient who has received chemotherapy, which in HSCT patients. (cdc.gov)
  • HSCT patients are presumed immunocompetent if they are at least 24 months post-HSCT, are not receiving immunosuppressive therapy, and do not have graft- versus-host disease (GVHD). (cdc.gov)
  • HSCT) has significantly modified the prognosis of when the pathological process involves BM or when patients with hereditary or acquired hematological, hematopoietic toxicity is the limiting factor in the oncological and immunological diseases and it is the aggressive treatment of the disease. (bvsalud.org)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • There are 9 sections in Reprints or correspondence: Dr. Clare A. Dykewicz, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Mailstop A12, Atlanta, GA 30333 (cad3 the guidelines. (cdc.gov)
  • from any individual except oneself and solar radiation, and most of the leukaemia by a genotoxic mech- or an identical twin will provoke an chemical alkylating agents used in anism after its use in anticancer immune reaction against the graft- anticancer chemotherapy. (who.int)
  • White blood cells of the donor's immune system which remain within the donated tissue (the graft) recognize the recipient (the host) as foreign (non-self). (wikipedia.org)
  • In the clinical setting, graft-versus-host disease is divided into acute and chronic forms, and scored or graded on the basis of the tissue affected and the severity of the reaction. (wikipedia.org)
  • In addition, M. Cheng reports a patent Methods for detecting tissue damage, graft versus host disease, and infections using cell-free DNA profiling pending, and a patent Methods for assessing the severity and progression of SARS-CoV-2 infections using cell-free DNA pending. (medrxiv.org)
  • They are sometimes referred to as rheumatic diseases, connective tissue disorders, or collagen vascular disorders. (ssa.gov)
  • Its severity depends on the differences in tissue type between patient and donor. (drcremers.com)
  • In persons with Kawasaki disease and dermatomyositis, IVIG is thought to inhibit the generation of membrane attack complexes (C5b-C9) and subsequent complement-mediated tissue damage by binding the activated components C3b and C4b, thus preventing their deposition on target surfaces. (medscape.com)
  • While disruption of immune homeostasis can occur systemically, it can also be localized to a specific tissue as seen in inflammatory disorders such as psoriasis, inflammatory bowel diseases, and tumors, thus underscoring the importance of immune homeostasis at tissue level in maintaining health. (jefferson.edu)
  • Patients with a history of immunodeficiency (except for acquired hypogammaglobulinemia), patients with active autoimmune disease requiring systemic immunosuppressive therapy (i.e. (moffitt.org)
  • Severe mucositis was defined as either grades 2 to 4 or grades 3 and 4, depending on the studies' definition of severity. (elsevierpure.com)
  • With a deep dive on the burden and diagnosis rates, and factors contributing to epidemiology changes, this report offers an essential tool for understanding the disease and planning better interventions. (researchandmarkets.com)
  • The overall objective of the guidelines is to provide up-to-date, evidence-based recommendations for the diagnosis and management of the full spectrum of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and SJS-TEN overlap in adults during the acute phase of the disease. (medscape.com)
  • The diagnosis of CMV pneumonia can be suggested by chest radiography findings, but these findings cannot be used to differentiate between other common causes of pneumonia in immunocompromised hosts. (medscape.com)
  • The rates of BMD impairment and VCF in our pediatric cohort were significantly higher than those seen in the adult AHSCT recipients who were concurrently enrolled on the same study at the NIH and had similar cGVHD severity. (qxmd.com)
  • 2. Autoimmune disorders (14.00D) . Autoimmune disorders are caused by dysfunctional immune responses directed against the body's own tissues, resulting in chronic, multisystem impairments that differ in clinical manifestations, course, and outcome. (ssa.gov)
  • This equilibrium between pro- and anti-inflammatory immune responses, termed " immune homeostasis ", is critical for the health of the host. (jefferson.edu)
  • Acquired aplastic anemia (AA) is a rare heterogeneous disease characterized by pancytopenia and hypoplastic bone marrow. (pedemmorsels.com)
  • The presence of a microorganism within a host may occur with varying duration, but may become a source of potential transmission. (cdc.gov)
  • GvHD can also occur after a blood transfusion , known as Transfusion-associated graft-versus-host disease or TA-GvHD if the blood products used have not been gamma irradiated or treated with an approved leukocyte reduction system. (wikipedia.org)
  • Formerly, negative pressure isolation room, an AIIR is a single-occupancy patient-care room used to isolate persons with a suspected or confirmed airborne infectious disease. (cdc.gov)
  • Background There is potentially considerable variation in the nature and duration of the care provided to hospitalised patients during an ongoing infectious disease epidemic or pandemic. (medrxiv.org)
  • The ECS is also involved in several pathophysiological diseases such as cancer, cardiovascular diseases, and neurodegenerative diseases. (thctotalhealthcare.com)
  • who are latently infected with an on- Certain pharmaceutical drugs, Immunosuppression as a medi- cogenic virus are at greatly increased ionizing and ultraviolet radiation, cal therapy is used to treat autoim- risk for developing virus-related or infection with certain viruses mune diseases such as lupus ery- cancers when they become immu- and parasites can cause immu- thematosus or rheumatoid arthritis. (who.int)
  • X-rays or other types of ionizing in much higher dosage, are used to and there is excess risk of B-cel radiation, immunosuppression is maintain the functional and anatom- non-Hodgkin lymphoma (NHL) when most pronounced if the entire body, ical integrity of foreign tissues graft- immunosuppression is accompanied rather than a limited area, is irra- ed onto another individual, such as by continuing immune stimulation diated. (who.int)
  • Home 1 / Graft vs. Host Disease 2 / Signaling Through the Type 2 Cannabinoid Receptor Regulates the Severity. (cannabisclinicians.org)
  • Medicine Central , im.unboundmedicine.com/medicine/view/Select-5-Minute-Pediatric-Consult/14101/all/Graft_Versus_Host_Disease. (unboundmedicine.com)
  • Specific Populations Pediatric Patients: In a pharmacokinetic study of BUSULFEX in 24 pediatric patients, the population pharmacokinetic (PPK) estimates of BUSULFEX for clearance (CL) and volume of distribution (V) were determined. (clustermed.info)
  • Proposals that increase the knowledge of efficacy and safety of immunoglobulins, specifically pharmacokinetics in chronic inflammatory demyelinating polyneuropathy (CIDP) including wear-off, dose titration, dose conversion from intravenous immunoglobulins (IVIg) to subcutaneous immunoglobulins (SCIg), loading dose and dosing by body mass index (BMI) or fat percent versus weight, quality-of-life in CIDP patients, health economics in CIDP and specific sub-populations, such as elderly and pediatric patients. (cslbehring.ch)
  • Treatment-related adverse events were reported in 24.8% versus 28.4%, and treatment related serious adverse events in 8.5% versus 6.5% of patients treated with placebo versus vedolizumab, respectively. (businesswire.com)
  • Dermatologic manifestations are an important aspect of graft versus host disease (GVHD). (medscape.com)
  • Patients may need to be treated for months to years depending on the symptoms and severity. (choa.org)
  • The disease- develop various infections at different times posttransplanta- specific sections address prevention of exposure and disease for tion, reflecting the predominant host-defense defect(s). (cdc.gov)
  • The cyclic peptide NR58-3.14.3 was shown to be a powerful anti-inflammatory agent in vivo, inhibiting inflammation in a number of disease models such as atherosclerosis, ischemia, lung disease, surgical adhesions, endometriosis and pulmonary graft-versus-host disease. (wikipedia.org)
  • However, excess inflammation can be harmful to the host and to counteract this process, the immune system has also evolved to modulate anti-inflammatory responses. (jefferson.edu)
  • The University of Chicago Medicine Comprehensive Cancer Center offers a multidisciplinary GVHD Clinic designed to prevent the disease and to provide comprehensive, prompt care for patients who develop it. (uchicagomedicine.org)
  • The doctors and specialists at the Aflac Cancer and Blood Disorders Center understand the importance of early detection and treatment for graft-versus-host disease (GVHD). (choa.org)
  • Oral beclomethasone dipropionate for treatment of human intestinal graft-versus-host disease. (nature.com)
  • Oral beclomethasone dipropionate for the treatment of gastrointestinal acute graft-versus-host disease (GVHD). (nature.com)
  • Historically, patients with this debilitating disease have had limited treatment options, and disease-modifying agents were not available. (cancernetwork.com)
  • This modulation results in the differential expression/activity of the components of the ECS that may be beneficial in the treatment of a number of diseases. (thctotalhealthcare.com)
  • This manuscript in-depth review will investigate the potential of the ECS in the treatment of various diseases, and to put forth the suggestion that many of these secondary metabolites of Cannabis sativa L. (hereafter referred to as " C. sativa L." or "medical cannabis"), may also have potential as lead compounds in the development of cannabinoid-based pharmaceuticals for a variety of diseases. (thctotalhealthcare.com)
  • Initial therapy of acute graft-versus-host disease with low-dose prednisone does not compromise patient outcomes. (nature.com)
  • Despite little evidence on how the values of such variables change over the course of a crisis (such as the current COVID-19 pandemic), they may nevertheless be used as proxies for disease severity, outcome measures for clinical trials, and to inform planning and logistics. (medrxiv.org)
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
  • In my laboratory, I plan on continuing studies to dissect the mechanisms underlying immune homeostasis in non-lymphoid tissues (peripheral tissues) such as the intestine, by focusing not only on GPR15 but also beyond, by setting up novel approaches, with the hope that such findings can be used to develop therapeutic methods for restoring the immune balance that is lost in inflammatory or infectious diseases and cancer. (jefferson.edu)
  • ed tissues, the intensity of which and chemical alkylating agents are varies with the degree of antigenic considered to cause cancer primar- Immunosuppressive difference between graft and host. (who.int)
  • In the 7MM, the acute graft-versus-host disease incident cases were ~10,340 in 2022, which are likely to increase to ~12,360 by 2032. (researchandmarkets.com)
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 12 76 (3): 521-527. (cdc.gov)
  • Many factors affect the balance between a graft-versus-tumor effect and GVHD, including genetic differences between donor and host and the magnitude of the T-cell response. (medscape.com)
  • The Neuroprotective Effects of the CB2 Agonist GW842166x in the 6-OHDA Mouse Model of Parkinson's Disease. (cannakeys.com)
  • Basile MS, Mazzon E. The Role of Cannabinoid Type 2 Receptors in Parkinson's Disease. (cannakeys.com)
  • Cell Therapy for Parkinson's Disease: What Next? (lu.se)
  • GVHD occurs when donor immune cells recognize and attack host antigens. (medscape.com)
  • We undertook a systematic review to determine the current evidence for the use of PROMs in assessment of QOL, symptom burden, and disease severity of patients with GVHD. (nih.gov)
  • Estimating influenza disease burden from population-based surveillance data in the United States. (cdc.gov)
  • Genetic Predisposition of Anti-Cytomegalovirus Immunoglobulin G Levels and the Risk of 9 Cardiovascular Diseases. (cdc.gov)
  • The physical assessment showed moderate ascites and small liver size, and no other peripheral evidence of chronic liver disease was observed. (bvsalud.org)
  • In the multifocal motor neuropathy disease state, IVIG intercedes to stop complement deposition that is triggered by anti-GM1 antibodies. (medscape.com)
  • interestingly, antibodies against granulocyte macrophage colony-stimulating factor, interferon, interleukin 1, and interleukin 6 in immune globulin have biologic activity in vivo. (medscape.com)