Severity of allergic lung disease. Medical search. Frequent questions

Co-morbidities of asthma include sinusitis, nasal polyposis, gastro-esophageal reflux disease (GERD) and allergic rhinitis. (medscape.com)
Results from the Asthma Phenotypes in the Inner City (APIC) study, reported in 2016, pinpointed sensitivity to multiple allergens, poor lung function, allergic rhinitis and exposure to second-hand smoke as major factors associated with asthma severity in children. (nih.gov)
Associations with lung function, bronchial hyper-responsiveness (BHR), allergic sensitisation, asthma and rhinitis were analysed. (bmj.com)
Recently, the presence of local allergy in the nasal cavity was found in a number of patients diagnosed previously with non-allergic rhinitis [ 6 - 8 ]. (j-rhinology.org)
WO2009074829 and WO2010142985 also disclose peptidyl nitrile inhibitors as dipeptidyl-peptidase I (DPPI) inhibitors for the treatment asthma, COPD or allergic rhinitis. (justia.com)
Clinical history of asthma and rhinitis was recorded, and lung function was assessed (spirometry, methacholine provocation and exhaled nitric oxide fraction). (ersjournals.com)
The work environment is one of the main causes of allergic rhinitis. (scirp.org)
The study determined the prevalence of allergic rhinitis and its associated risk factors in these vendors. (scirp.org)
Symptoms of allergic rhinitis were defined as the simultaneous presence of rhinorrhea, nasal congestion and sneezing in the absence of respiratory infection. (scirp.org)
A logistic regression analysis was performed to determine the relationship between socio-demographic characteristics, occupational factors, and allergic rhinitis. (scirp.org)
Results of the study show a prevalence of 43% of allergic rhinitis among vendors. (scirp.org)
The prevalence of allergic rhinitis was high among vendors in Dakar. (scirp.org)
Our data suggest that exposure to air pollution at the workplace in vendors could lead to allergic rhinitis. (scirp.org)
The causes of the increase in the prevalence of allergic rhinitis remain to be determined. (scirp.org)
In sub-Saharan Africa, the International Study of Asthma and Allergies in Childhood (ISAAC) survey [10] showed the existence of allergic rhinitis with differences in prevalence between countries ranging from 7.5% in Ethiopia to 49% in Ivory Coast. (scirp.org)
Air pollution from cars is therefore a major risk factor for increasing the prevalence of allergic rhinitis. (scirp.org)
However, this association is not widely known in developing countries because the majority of epidemiological studies on air pollution from road traffic and allergic rhinitis are done in developed countries. (scirp.org)
Many people with ABPA also suffer from allergic conditions such as atopic dermatitis (eczema), urticaria (hives) , allergic rhinitis (hay fever) and sinusitis . (aaaai.org)

Various lung insults, including air pollution, smoking and allergens can induce reactive oxygen species (ROS) in the lung [ 1 ]. (ersjournals.com)
1 The onset of asthma is often preceded by allergic disease (eczema or hay fever) and a positive result of skin tests with allergens (atopy). (bmj.com)
Some people suffer asthma attacks when they breathe in allergens (small particles capable of causing allergic reactions, such as pollens and moulds), and when traffic pollution is high. (ukbiobank.ac.uk)
This 3-year project will identify determinants that influence the frequency and severity of asthma attacks and the occurrence of other allergic diseases, what makes people more vulnerable to outdoor allergens and whether exposure to traffic pollution makes it worse. (ukbiobank.ac.uk)

Whilst usually benign in nature, they can sometimes cause symptoms such as cough or an exacerbation of existing disease such as asthma. (wikipedia.org)
Beyond the direct symptoms, it is possible to have general signs of underlying lung pathology such as digital clubbing-especially when there has been an underlying disease such as tuberculosis or where disease has caused heart failure (known as cor pulmonale). (wikipedia.org)
Depending on the severity of the condition, people with asthma may experience mild symptoms or a flare-up of symptoms, an " asthma attack . (everydayhealth.com)
In individuals with milder cases of asthma, symptoms may occur rarely and be easy to manage with treatment - but for others with what's considered severe asthma, symptoms occur daily or more frequently and are difficult to manage with treatment, according to the National Heart, Lung, and Blood Institute . (everydayhealth.com)
Some people with allergic asthma , for example, may experience an allergic reaction from essential oils that triggers their asthma symptoms , he says. (everydayhealth.com)
2 3 Impaired lung function in childhood predicts asthmatic symptoms as a teenager, although this association might be confounded by undiagnosed asthma. (bmj.com)
For employees who work in construction, trade occupations, industrial, mechanics and HVAC, daily exposures to harmful substances can build up over time and cause symptoms of lung problems. (ohsonline.com)
Workers who stay inside more frequently can have worsened symptoms of pre-existing respiratory diseases or not be able to escape these pollutants. (ohsonline.com)
People with respiratory diseases may find their symptoms aggravated by both the winter season and where you work. (ohsonline.com)
Lung inflammation and shortness of breath are also symptoms of coal dust exposure. (ohsonline.com)
The first indications of allergic bronchopulmonary aspergillosis are usually symptoms such as wheezing, cough, and shortness of breath, and a mild fever. (msdmanuals.com)
Traditionally, asthma has been regarded as a disease characterised by chronic inflammation and remodelling, primarily of the large airways, which leads to airflow obstruction and asthma-specific symptoms. (ersjournals.com)
Hence, Hogg and colleagues, who also first used the term "small airway disease" [ 7 ], described the distal airways as the "silent zone" of the airway tree as extensive disease can be present without symptoms or changes in conventional lung function tests [ 14 ]. (ersjournals.com)
To classify your asthma severity, your doctor will consider how often you have signs and symptoms and how severe they are. (mayoclinic.org)
Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML): Monitor patients with breast and lung cancer using UDENYCA in conjunction with chemotherapy and/or radiotherapy for signs and symptoms of MDS/AML. (drugs.com)
Symptoms of White Fungus immune systems or lung diseases their lifetime, women have a 40 to 50 risk be due to another condition. (descansario.com)
However, even if your cat's symptoms seem to disappear, it is very important to continue with treatment because the underlying inflammation is still simmering and can cause long-term disease. (petmd.com)
The signs and symptoms vary and can range from mild to life-threatening depending on the type of vasculitis, the specific affected area and the severity of the condition. (outsourcestrategies.com)
Moreover, asthma symptoms correlate poorly with abnormalities of lung function 9 and airway inflammation, 10 , 11 and thus in isolation may suggest a less severe form of the disease than is actually present. (cmaj.ca)
Asthma is an inflammatory disease 13 associated with symptoms resulting from abnormalities of airway function, in particular wide, short-term variations in airflow resistance in the intrapulmonary airways. (cmaj.ca)
The chronic inflammation of asthma is associated with airway hyperresponsiveness that leads to recurrent symptoms, yet lung function may nevertheless remain normal. (cmaj.ca)

Some people with allergic asthma may experience allergic reactions to essential oils. (everydayhealth.com)
Allergic reactions to mold are the most common health effects of mold. (pureairenvironmental.com)
Allergic reactions may happen immediately or develop after a period of time following exposure. (pureairenvironmental.com)
Both growing mold and mold spores may lead to allergic reactions. (pureairenvironmental.com)
Allergic reactions may occur in multiply-exposed individuals with extreme inflammatory response around the exposed area of the skin. (cdc.gov)
Serious allergic reactions, including anaphylaxis: Permanently discontinue UDENYCA in patients with serious allergic reactions. (drugs.com)
Patients with a history of serious allergic reactions to human granulocyte colony-stimulating factors such as pegfilgrastim products or filgrastim products. (nih.gov)
The condition can occur either on its own, or may be linked to certain other factors like immune system disorders, infections (hepatitis B or C), allergic reactions to medications, and certain types of cancers (such as leukemia and lymphoma). (outsourcestrategies.com)

Aerocrine, Inc. announced the following scientific abstract, Characterization of Allergic Airway Inflammation in Patients with COPD using Fractional exhaled Nitric Oxide Level (FeNO)s, presented at the 2013 American Thoracic Society International Conference. (technologynetworks.com)
Asthma can coexist with chronic obstructive pulmonary disease (COPD), particularly in older adults, a condition labeled overlap syndrome. (technologynetworks.com)
COPD severity was classified according to guidelines from the Global Initiative for Chronic Obstructive Lung Disease (GOLD). (technologynetworks.com)
Pulmonologists are learning how they can help direct treatment for asthma patients, but with this additional clinical research we are demonstrating that because of overlap disease it can also help for care of their patients with COPD who may have an asthma component (Overlap Syndrome). (technologynetworks.com)
Your doctor will perform a physical exam to rule out other possible conditions, such as a respiratory infection or chronic obstructive pulmonary disease (COPD). (mayoclinic.org)
For example, asbestos makes development of lung cancer more likely, while coal mine dust causes chronic obstructive pulmonary disease (COPD) through incremental loss of lung function. (sjweh.fi)
Thus, inhibitors of Cathepsin C could potentially be useful therapeutics for the treatment of neutrophil-dominated inflammatory diseases such as chronic obstructive pulmonary disease (COPD), pulmonary emphysema, asthma, multiple sclerosis, and cystic fibrosis (Guay et al. (justia.com)
2007). Vitamin D may also play a role in the development of obstructive lung diseases like asthma and COPD (Janssens, Lehouck et al. (vitamindwiki.com)
IFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes. (medscape.com)

Many people affected by chronic pulmonary aspergillosis have an underlying lung disease, most commonly tuberculosis, allergic bronchopulmonary aspergillosis, asthma, or lung cancer. (wikipedia.org)
Allergic bronchopulmonary aspergillosis is an allergic lung reaction to a type of fungus (most commonly Aspergillus fumigatus ) that occurs in some people with asthma or cystic fibrosis. (msdmanuals.com)
In allergic bronchopulmonary aspergillosis, in contrast, the fungus does not actually invade the lung tissue and directly destroy it. (msdmanuals.com)
Six patients (6/20, 30%) exhibited allergic bronchopulmonary aspergillosis (ABPA). (biomedcentral.com)
Allergic bronchopulmonary aspergillosis (ABPA) is an allergic or hypersensitive reaction to a fungus known as Aspergillus fumigatus. (aaaai.org)
A case of allergic bronchopulmonary aspergillosis successfully treated with mepolizumab. (medscape.com)

Mechanistic and therapeutic approaches to occupational exposure-associated allergic and non-allergic asthmatic disease. (cdc.gov)
examine BAL samples from asthmatic patients challenged with diluent or allergen, and from patients with/without AHR, to establish the specific oxidised PCs that associate with AHR and are induced by allergic lung challenge. (ersjournals.com)
2 ] hypothesised that the phosphatidylcholines are prime oxidising targets in the asthmatic airway based on their relative abundance, and that oxidised phosphatidylcholines (OxPC) are mechanistic effectors of oxidised stress in asthma, suggested by prior research demonstrating the ability of OxPC to perpetuate inflammation in ageing-related diseases, and their known causal role in both acute lung injury and acute respiratory distress syndrome [ 3 - 5 ]. (ersjournals.com)
Schwab, AD & Poole, JA 2023, ' Mechanistic and Therapeutic Approaches to Occupational Exposure-Associated Allergic and Non-Allergic Asthmatic Disease ', Current allergy and asthma reports , vol. 23, no. 6, pp. 313-324. (nebraska.edu)
2000. Exhaled nitric oxide as an indicator of severity of asthmatic inflammation. (cdc.gov)
Environmental exposure in sensitized individuals is a major inducer of airway inflammation, which is a hallmark finding in the asthmatic lung. (medscape.com)

One relevant sample type for investigating chronic lung inflammation is bronchoalveolar lavage fluid (BALF), which provides a snapshot of the immune cells present in the alveolar space. (bvsalud.org)
Twenty-four hours after the final challenge, the lungs and bronchoalveolar lavage fluid (BALF) were collected to assess AAD. (nature.com)
Elevated α-defensin levels in plasma and bronchoalveolar lavage fluid from patients with myositis-associated interstitial lung disease. (medscape.com)

The respiratory disease causes sporadic inflammation and narrowing of the airways in the lungs, leading to spells of wheezing , chest tightness, and shortness of breath . (everydayhealth.com)
Have you ever been diagnosed with asthma (an allergic respiratory disease)? (worldbank.org)
This question serves to identify individuals with a diagnosed case of asthma (sometimes called an allergic respiratory disease). (worldbank.org)
Asthma is the most common chronic respiratory disease worldwide. (ukbiobank.ac.uk)
Asthma is the most common chronic respiratory disease in Canada, affecting about 2.2 million adults and 0.8 million children. (cmaj.ca)
For these reasons, major epidemics of respiratory disease caused by new variants of influenza continue to occur. (cdc.gov)

The prevalence of asthma and allergic sensitization was 4 and 6 times lower in the Amish population, with higher median endotoxin levels in house dust. (medscape.com)
The frequency, severity and preventability of occupational lung diseases contribute to the ongoing prevalence. (ohsonline.com)
Estimates of relative risk for paired combinations of occupational risk factor and disease were collated with data on the population prevalence of exposure to calculate population attributable fractions (PAF) (3), which then were multiplied by estimates of the total population impact of the disease (in terms of deaths and disability-adjusted life-years) to derive burdens attributable to occupation (2). (sjweh.fi)
This survey will help NCHS and CBER, FDA measure the prevalence of allergies in the United States and determine if the prevalence has changed since previous HANES surveys, which indicated that approximately 20 percent of the U.S. population is affected by allergic diseases. (cdc.gov)
Due, in part, to the increasing prevalence impact these exposures have on the large number of affected of this disease, the possible relationship between asthma and patients and potentially susceptible consumers. (cdc.gov)
Prevalence of pre-transplant anti-HLA antibodies and their impact on outcomes in lung transplant recipients. (medscape.com)
The prevalence, burden and risk factors associated with chronic obstructive pulmonary disease in Commonwealth of Independent States (Ukraine, Kazakhstan and Azerbaijan): results of the CORE study. (medscape.com)

The term describes several disease presentations with considerable overlap, ranging from an aspergilloma-a clump of Aspergillus mold in the lungs-through to a subacute, invasive form known as chronic necrotizing pulmonary aspergillosis which affects people whose immune system is weakened. (wikipedia.org)
Chronic pulmonary aspergillosis as a term encompasses a number of different presentations of varying severity. (wikipedia.org)
This leads to a state known colloquially as "destroyed lung", and has features resembling treated pulmonary tuberculosis. (wikipedia.org)
It is more common in people who are elderly or dependent on alcohol, or with diseases such as diabetes, malnutrition, chronic obstructive pulmonary disease or HIV/AIDS. (wikipedia.org)
Chronic pulmonary aspergillosis can cause bleeding into the lung parenchyma which can range from mild to life-threatening. (wikipedia.org)
The third section follows with chapters on associations of vitamin D with the risk for viral infections, asthma and allergies, chronic obstructive pulmonary disease, cystic fibrosis, tuberculosis, and finally, lung cancer with an emphasis on ongoing research and clinical issues and needs for future research in each field. (vitamindwiki.com)
It can advance throughout the lungs to more severe dyspnea, pulmonary hypertension and respiratory impairment. (ohsonline.com)
In the 1970s, the first physiological studies using indirect measurements of the distal airways (primarily nitrogen washout) focused attention on the role of small airways in diseases like asthma and chronic obstructive pulmonary disease [ 15 - 17 ]. (ersjournals.com)
There may also be pulmonary function evidence of restrictive lung disease (10,12). (cdc.gov)
Which factors may be predictive of postoperative pulmonary complications among patients with pulmonary diseases? (medscape.com)
The cutoff point of clinical chronic obstructive pulmonary disease questionnaire for more symptomatic patients. (medscape.com)

By clarifying the roles of both host- (genetic) and virus- (environment) specific factors that contribute to the frequency and severity of viral LRTI, it may be possible to determine if severe LRTIs cause asthma, or if asthma susceptibility predisposes patients to severe LRTI in response to viral infection. (atsjournals.org)
Overview of Pneumonia Pneumonia is an infection of the small air sacs of the lungs (alveoli) and the tissues around them. (msdmanuals.com)
Aspergillosis Aspergillosis is an infection, usually of the lungs, caused by the fungus Aspergillus . (msdmanuals.com)
This condition is an infection, not an allergic reaction. (msdmanuals.com)
The manifestations of zoonotic hookworm infection are the result of inflammatory reaction to the migrating larvae in the skin or, less commonly, migration in deeper tissues such as lungs, intestinal tract, or possibly the eye. (cdc.gov)
Single tracks or multiple tracks may be present, depending on the severity of infection. (cdc.gov)
Infection, genes, and hormone changes may be linked to the disease. (medlineplus.gov)
The soil of parks and playgrounds is commonly contaminated with the eggs of T canis, and infection may cause human disease that involves the liver, heart, lung, muscle, eye, and brain. (medscape.com)
A chest X-ray can help identify any structural abnormalities or diseases (such as infection) that can cause or aggravate breathing problems. (mayoclinic.org)
This is especially the case in young children where infectious illnesses are commonly associated with skin rashes (exanthema, and urticaria) and antibiotics used in the context of acute infection can be incorrectly labelled as the allergic trigger. (hse.ie)
These cellular effects are important for host responses against infection and the development of allergic lung diseases like asthma. (vitamindwiki.com)
Immunity to these antigens -- especially to the hemagglutinin -- reduces the likelihood of infection and lessens the severity of disease if infection occurs. (cdc.gov)

Cystic Fibrosis (CF) Cystic fibrosis is a hereditary disease that causes certain glands to produce abnormally thick secretions, resulting in tissue and organ damage, especially in the lungs and the digestive tract. (msdmanuals.com)

Allergic asthma is the most common type of asthma , affecting roughly 60 percent of the more than 25 million Americans with asthma, according to the Asthma and Allergy Foundation of America . (everydayhealth.com)
The National Heart, Lung, and Blood Institute will use the allergy data in conjunction with other exam and interview data to increase our understanding of chronic obstructive lung disease. (cdc.gov)
CST1 is thus a possible biomarker of the severity of allergic airway disease and a possible therapeutic target for the future treatment of airborne allergy. (ersjournals.com)

In some people, the effects of the allergic reaction combine with the effects of the fungus to damage the airways and lungs. (msdmanuals.com)
This may damage the airways and result in permanent lung damage. (aaaai.org)

In an ovalbumin (OVA)-induced murine model of allergic lung disease, CBA/Ca mice develop much lower levels of lung eosinophilia, lung oedema, mucus hypersecretion and airways obstruction than BALB/c and C57BL/6 strains. (sahmri.org.au)
This obstruction of the lungs is reversible, either spontaneously or with medication. (worldbank.org)
On the co-primary endpoints for both trials at 24 weeks, patients treated with Dupixent (dupilumab) added to a standard-of-care corticosteroid nasal spray experienced a 51% and 57% improvement in their nasal congestion/obstruction severity compared to 15% and 19% improvement with nasal spray alone. (pharmatimes.com)

Following immunization with OVA, CBA/Ca mice developed a robust systemic allergic response, with high levels of total and OVA-specific IgE and increases in peripheral blood eosinophils. (sahmri.org.au)
It can also occur due to certain rheumatic diseases such as rheumatoid arthritis, systemic lupus erythematosus (SLE/ lupus) or Sjogrens syndrome. (outsourcestrategies.com)

The presence of multiple types of ROS associates with asthma severity and cardinal features of the disease, including airway hyperresponsiveness (AHR) and inflammation. (ersjournals.com)
Asthma is a heterogeneous disease characterized by airway chronic inflammation together with airway hyperresponsiveness 1 . (nature.com)
Results showed significant and clinically important treatment benefits on markers such as lung function, airway hyperresponsiveness and exhaled nitric oxide, which are all predictors of the risk of future adverse outcomes such as exacerbations. (health.am)

The drop in temperature, weakening of the immune system and shortage of sunlight can produce seasonal respiratory diseases. (ohsonline.com)
Aspergillus can invade the lungs and cause serious pneumonia in people with an impaired immune system. (msdmanuals.com)
Specific pathogen may play a critical role in the allergic airway diseases (AAD) pathogenesis by affecting the immune system 5 . (nature.com)
Studies have shown that the enzyme 1a- hydroxylase, which catalyzes the last and rate limiting step in the synthesis of active 1,25- dihydroxyvitamin D3 (1,25D), and the vitamin D receptor (VDR), which mediates the actions of vitamin D, are expressed widely in the body, including the lungs and cells of the immune system. (vitamindwiki.com)
However, in certain people, the immune system overreacts to the antigens of Aspergillus fumigatus found in the lungs. (aaaai.org)

Asthma is a chronic disease in which the airways in the lungs become inflamed. (nih.gov)

Objectives To investigate the influence of childhood living environment and biodiversity indicators on atopy, asthma and lung function in adulthood. (bmj.com)

It is an autoimmune disease. (medlineplus.gov)
Poor indoor air quality can lead to health problems such as headaches, fatigue, respiratory issues, and even long-term health effects like heart disease and autoimmune disorders. (scottleeheating.com)

Examples include collapsed lungs which have formed bullae, chronic obstructive lung disease, lung cancer, and fibrocavitary sarcoidosis. (wikipedia.org)
Oxidative stress is a major pathogenic driver in many diseases, and evidence to date suggests the obstructive lung disease asthma is no exception. (ersjournals.com)

The dose, exposure frequency, and nature of the causal agent influence the inflammatory pathomechanisms that inform asthma disease phenotype and progression. (cdc.gov)
While surveillance, systems engineering, and exposure mitigation strategies are essential preventative considerations, no targeted medical therapies are currently available to ameliorate lung injury post-exposure and prevent chronic airway disease development. (cdc.gov)
Summary: The course of occupational lung disease that follows exposure is informed by individual predisposition, immunobiologic response, agent identity, overall environmental risk, and preventative workplace practices. (cdc.gov)
Risk factors for asthma include a family history of allergic disease, the presence of allergen-specific immunoglobulin E (IgE), viral respiratory illnesses , exposure to aeroallergens , cigarette smoke, obesity , and lower socioeconomic status. (medscape.com)
Rationale Evidence has suggested that exposure to environmental or microbial biodiversity in early life may impact subsequent lung function and allergic disease risk. (bmj.com)
This uncommon disease is similar to pneumonia and can develop in susceptible individuals after brief or prolonged exposure to mold. (pureairenvironmental.com)
Such attribution is straightforward where a disease occurs only as a consequence of occupational exposure (eg, coal workers' pneumoconiosis, byssinosis). (sjweh.fi)
Exposure to cotton, flax, or hemp dust is also associated with disease. (cdc.gov)
The severity of health consequences can vary depending on the individual's sensitivity to pollutants and the duration of exposure. (scottleeheating.com)
Despite continuous exposure to potential pathogens only rarely do the lungs become colonized or infected. (vitamindwiki.com)
Asthma is gener- exposure to consumer products is gaining public attention and ally defined as a chronic inflammatory disease of the lung increasingly becoming a research priority. (cdc.gov)
CC16 levels correlate with cigarette smoke exposure in bronchial epithelial cells and with lung function decline in smokers. (medscape.com)

Clinical data available for each subject also allowed correlation analyses between specific OxPC levels and lung function data. (ersjournals.com)
It is not known whether viral bronchiolitis directly contributes to asthma causation or simply identifies infants at risk for subsequent wheezing, as from an atopic predisposition or preexisting abnormal lung function. (atsjournals.org)
You may be given lung function tests to determine how much air moves in and out as you breathe. (mayoclinic.org)
Lung function tests often are done before and after taking a medication to open your airways called a bronchodilator (brong-koh-DIE-lay-tur), such as albuterol. (mayoclinic.org)
If your lung function improves with use of a bronchodilator, it's likely you have asthma. (mayoclinic.org)
This test may be used even if your initial lung function test is normal. (mayoclinic.org)
Air pollution from truck traffic and lung function in children living near motorways. (cdc.gov)
For example, exacerbation of pre-existing asthma by occupational inhalation of irritants may be apparent from serial measurements of lung function when an employee is at, and away from, work. (sjweh.fi)
Moreover, in CRSwNP patients, the severity of disease was related with blood eosinophil (%), eosinophil (%), and ECP levels in NLFs, whereas olfactory function was associated with blood eosinophil (%) and ECP levels in NLFs. (j-rhinology.org)
CRSwNP is a disease with high allergic inflammation that has negative impacts on the severity of disease and olfactory function. (j-rhinology.org)
Also of note, in a pre-specified group of patients with comorbid asthma, Dupixent significantly improved lung function and asthma control. (pharmatimes.com)
A study by the Woolcock Institute of Medical Research in Sydney is the first to demonstrate that in patients with very mild or well-controlled asthma, regular treatment with low dose ICS leads to significantly better day-to-day lung function. (health.am)
Results indicated that a "ceiling" effect for lung function, often assumed to prevail in mild asthma, does not exist. (health.am)
Even patients whose lung function is over 90% of predicted normal value may have room to further improve their personal best with treatment. (health.am)
However for those participants receiving ICS during the study, their lung function was better, they had less airway inflammation and less airway twitchiness. (health.am)
The clinical value of using digital tools to assess adherence and lung function in uncontrolled asthma is not known. (cdc.gov)

Rheumatoid arthritis (RA) is a disease that leads to inflammation of the joints and surrounding tissues. (medlineplus.gov)
DPPI is constitutively expressed in many tissues with highest levels in lung, kidney, liver and spleen (Kominami et al. (justia.com)
Vitamin D generated in tissues is responsible for many of the immunomodulatory actions of vitamin D. The effects of vitamin D within the lungs include increased secretion of the antimicrobial peptide cathelicidin, decreased chemokine production, inhibition of dendritic cell activation and alteration of T cell activation. (vitamindwiki.com)

Background: Acute kidney injury (AKI) commonly occurs in coronavirus disease 2019 (COVID-19) patients who have been hospitalised and is associated with a poor prognosis. (bvsalud.org)
Lung infiltrates are commonly apparent on chest X-rays. (cdc.gov)

Cat asthma is a recurring respiratory (breathing) condition that is characterized by inflammation (swelling) in the lungs and narrowing of the airways. (petmd.com)

5 Predictors of asthma in adulthood include various markers of initial severity,*RF 6-8* other atopic conditions, 4 7 8 and a family history of asthma. (bmj.com)
Vitamin A concentrations in lung, serum and liver were measured post pneumonia until early adulthood. (nature.com)
Whether neonatal S. pneumoniae pneumonia promoted adulthood allergic asthma was associated with vitamin A levels remains unclear. (nature.com)
In this study, we established a neonatal non-lethal S. pneumoniae pneumonia mice model and monitored vitamin A levels in lung, serum and liver until early adulthood. (nature.com)
We also explored the effects of vitamin A supplement after neonatal S. pneumoniae pneumonia on the development of adulthood allergic asthma. (nature.com)

The pathological understanding is further complicated by the influences of disease severity, the complexities of the lung itself and the associated heterogeneity of pathological changes throughout the bronchial tree. (ersjournals.com)

Pneumonias are lung infections that are usually caused by bacteria, viruses, and most fungi. (msdmanuals.com)
People with compromised immune systems or those with chronic lung disease can develop serious infections of the lungs due to molds. (pureairenvironmental.com)
These observations have led to a surge of epidemiological and basic research studies examining the effects of vitamin D on immune responses, lung infections and the development of lung diseases. (vitamindwiki.com)

Numerous reviews on the importance of small airways in asthma and other airway diseases have been published in recent years, including the following [ 8 - 12 ]. (ersjournals.com)

How often asthma attacks happen, as well as how severe they are, is influenced by a person's sex, age, if they smoke, whether they have other allergic diseases such as hayfever and eczema, as well as many other factors. (ukbiobank.ac.uk)

CONCLUSIONS: The data suggest that the frequency of MCps increases in symptomatic patients with allergic asthma. (bvsalud.org)
FeNO is useful for identifying patients with allergic airway inflammation who will have a beneficial response to treatment with an inhaled corticosteroid. (technologynetworks.com)

Background The clinical presentation of children sensitised to dog dander varies from asymptomatic to severe allergic airway disease, but the genetic mechanisms underlying these differences are not clear. (ersjournals.com)
Conclusions Overexpression of CST1 is associated with more severe allergic airway disease in children sensitised to dog dander. (ersjournals.com)
Severe allergic reaction . (medicalnewstoday.com)
Clinical and economic impact of a one-year treatment with omalizumab in patients with severe allergic asthma within a drug programme in Poland. (medscape.com)

We look forward to US regulatory action on our moderate-to-severe asthma application later this month, and are continuing our development program in additional Type 2 or allergic inflammatory diseases with high unmet need including pediatric asthma, pediatric and adolescent atopic dermatitis, eosinophilic esophagitis, and food and environmental allergies. (pharmatimes.com)

Eosinophilic pneumonitis has been reported to occur in patients with CLM, possibly due to deeper larval penetration involving the lungs. (cdc.gov)

The MCp frequency was determined by flow cytometry in ficoll-separated blood samples from patients with positive birch pollen-specific IgE, and analyzed in relation to basic and disease parameters. (bvsalud.org)
Because of the frequency and seriousness of these risks, we are alerting health care professionals and patients about them and that we are continuing to evaluate this potential safety issue with Prolia use in patients with advanced kidney disease, particularly those on dialysis. (medlineplus.gov)

Recently, there has been an interest in the role that vitamin D plays in the inception and progression of lung disease. (vitamindwiki.com)
Our data suggest that neonatal S. pneumoniae pneumonia induce serum vitamin A deficiency and long-time lung vitamin A reduction, vitamin A supplement after neonatal S. pneumoniae pneumonia inhibit the progression of asthma by altering CD4 + T cell subsets. (nature.com)
HYCAMTIN® for injection, as a single agent, is indicated for the treatment of patients with metastatic ovarian cancer after disease progression on or after initial or subsequent chemotherapy. (globalrph.com)
The recommended dosage of HYCAMTIN for injection is 1.5 mg/m² by intravenous infusion over 30 minutes daily for 5 consecutive days, starting on Day 1 of a 21-day cycle until disease progression or unacceptable toxicity. (globalrph.com)
Elucidation of the time course of disease onset, the mechanisms of disease progression, and the identity of etiologic agents is essential for effective prevention and treatment. (cdc.gov)

If uncontrolled, chronic lung damage may develop. (msdmanuals.com)

Severity also varies, with some asthma attacks being only mild while others can quickly become life threatening. (worldbank.org)

Purpose of Review: Occupational lung disease, including asthma, is a significant cause of disability worldwide. (cdc.gov)
Recent Findings: This article reviews contemporary understanding of allergic and non-allergic occupational asthma mechanisms. (cdc.gov)
When protective strategies fail, knowledge of underlying disease mechanisms is necessary to inform targeted therapy development to lessen occupational asthma disease severity and occurrence. (cdc.gov)
Particulate matter from occupational work is the primary source of respiratory diseases. (ohsonline.com)
Smoking in general drastically increases the risk for cancer and respiratory complications, but it can similarly provoke occupational lung diseases. (ohsonline.com)
2003. American Thoracic Society Statement: Occupational Contribution to the Burden of Airway Disease. (cdc.gov)
Occupational Diseases and Environmental Medicine , 5 , 106-120. (scirp.org)

However, subsequent physiological, imaging and pathological studies demonstrated that the small airways and even the lung parenchyma could be important contributors to the functional impairment seen in certain severe asthma patients, as some reports suggest asthma severity increases in proportion to the involvement of this compartment [ 5 , 6 ]. (ersjournals.com)

If left untreated, as the disease progresses the fungus can spread into the bloodstream causing a state known as fungemia. (wikipedia.org)
When workers consistently breathe in various substances including bacteria, certain chemicals and fungus spores, they can have an allergic lung disease. (ohsonline.com)
Certain people who inhale the fungus may become sensitized and develop a chronic allergic reaction. (msdmanuals.com)
A ball of fungus fibers, blood clots, and white blood cells may form in the lungs or sinuses. (msdmanuals.com)

The use of this medication depends upon the individual and the severity of ABPA. (aaaai.org)
If you are diagnosed with ABPA, you should be followed closely by your physician in order to prevent or minimize damage to your lungs. (aaaai.org)

Centers for Disease Control and Prevention. (cdc.gov)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. (cdc.gov)

CRSwNP is a chronic disease in which Type 2 or allergic inflammation causes polyps that obstruct the sinus and nasal passages, leading to severe congestion, nasal discharge, facial pain or pressure, and reduced sense of smell and taste. (pharmatimes.com)

Acute respiratory distress syndrome (ARDS): Evaluate patients who develop fever, lung infiltrates, or respiratory distress. (drugs.com)
This illness is called organic dust toxic syndrome (ODTS) and is syn- onymous with grain fever, silo unloaders' disease, inhalation fever, and toxic pneu- monitis. (cdc.gov)

Contribution: We propose a risk-based approach to guide clinical management of high risk patients, which departs significantly from the current disease-based model. (bvsalud.org)
Some reports have described delayed onset and persistent clinical diseases. (cdc.gov)
The results indicate that recently developed polygenic biomarkers for asthma, allergic disease, and COVID-19 hospitalization capture some of the individual differences in severity and clinical course of COVID-19 illness in a community population. (cdc.gov)

Any diagnostic procedure in severe asthma (or any disease) should have two aims: 1) better understanding or identifying the diagnosis, and 2) providing information on the heterogeneity of asthma phenotypes to guide therapy with the objective of improving outcomes. (ersjournals.com)
Mendelian randomization analysis confirms phenotypes across many organ systems, including conditions of the circulatory (heart failure, ischemic heart disease, atrial fibrillation), genitourinary (chronic renal failure), respiratory (respiratory failure, asthma), musculoskeletal and dermatologic systems. (cdc.gov)

both of whom tend to have increased amounts of mucus) and causes recurrent allergic inflammation in the lung. (msdmanuals.com)

Relatively little is known about the associations between PRS and COVID-19 severity or post-acute COVID-19 in community-dwelling individuals. (cdc.gov)

The larvae penetrate the bowel wall and migrate through vessels to the muscles, liver, and lung and sometimes to the eye and brain. (medscape.com)

As a result of the ongoing inflammation over an extended period of time, extensive fibrosis of the lung parenchyma occurs. (wikipedia.org)
Lung biopsies can target the large and small airways as well as the lung parenchyma. (ersjournals.com)

Vitamin D and the Lung: Mechanisms and Disease Associations delivers a concise, evidence-based review of the evidence for a role of vitamin D in various lung disorders. (vitamindwiki.com)
he second section of the book reviews aspects of vitamin D mechanisms on different immune cells, lung tissue, and genetics that have potential impact on lung disease. (vitamindwiki.com)
Written by an international group of expert authors, Vitamin D and the Lung: Mechanisms and Disease Associations is an essential text for researchers in the respiratory field and practicing clinicians including internists, pulmonologists, and primary care personnel. (vitamindwiki.com)
In this study these strains have been examined to identify mechanisms that control the recruitment and survival of eosinophils in the allergic lung. (sahmri.org.au)
These can be grouped into allergic, inflammatory, neurogenic, and physical mechanisms with current evidence in favour of a combination of allergic and inflammatory processes. (edu.pk)

[ 3 ] In Western countries, the financial burden on patients ranges from $300 to $1,300 per patient year, increasing with more severe disease. (medscape.com)

They leave permanent lung tissue scarring from the remaining asbestos that sticks to the lining of your lungs. (ohsonline.com)
Organic dust inflames the air sacks and scar tissue in the lungs. (ohsonline.com)
VetRxDirects staff is friendly, quick, knowledgeable, and they really go the extra mile to make sure your pet is taken care of If you are experiencing any about 10 minutes, let it cool off and gurgle the infusion around your mouth 2 Gingivitis is inflammation of the gum tissue and its an extremely common disease that can lead to receding gums. (descansario.com)

Four weeks after pneumonia, mice were sensitized and challenged with OVA to induce allergic airway disease (AAD). (nature.com)
Morbidity and mortality related to pneumonia and TRACHEOBRONCHITIS in ICU after lung transplantation. (medscape.com)

BALB/c mice expressed the highest levels of the eosinophil growth and survival factor interleukin (IL)-5 in the lungs and BAL eosinophils from these animals expressed more of the anti-apoptotic proteins Bcl-x L and Bcl-2 than cells from the other strains. (sahmri.org.au)
BALB/c mice expressed the highest levels of the eosinophil growth and survival factor interleukin (IL)-5 in the lungs and BAL eosinophils from these animals expressed more of the anti-apoptotic proteins Bcl-xL and Bcl-2 than cells from the other strains. (sahmri.org.au)

If exposed to both, their asthma may become very severe as breathing in traffic pollution can make the lungs especially sensitive. (ukbiobank.ac.uk)

Anatomy9

Organisms6

Diseases33

Chemicals and Drugs12

Analytical, Diagnostic and Therapeutic Techniques and Equipment25

Psychiatry and Psychology1

Phenomena and Processes5

Information Science1

Named Groups2

Health Care7

Rhinitis18

Allergens4

Symptoms21

Reactions8

COPD9

Bronchopulmonary6

Asthmatic6

Bronchoalveolar lavag3

Respiratory disease6

Prevalence7

Pulmonary11

Infection12

Cystic fibrosis1

Allergy3

Damage the airways2

Obstruction3

Systemic2

Hyperresponsiveness3

Immune System5

Airways in the lungs1

Atopy1

Autoimmune2

Obstructive2

Exposure12

Function16

Tissues3

Commonly2

Narrowing of the airways1

Adulthood5

Bronchial1

Infections3

Airway diseases1

Eczema1

Patients with allergic2

Severe allergic4

Atopic1

Occur1

Frequency2

Progression5

Chronic lung1

Mild1

Occupational7

Increases1

Fungus4

ABPA2

Centers for Diseas3

Inflammation causes1

Fever2

Clinical3

Phenotypes2

Recurrent1

Acute1

Liver1

Parenchyma2

Mechanisms5

Increasing with more severe1

Tissue3

Pneumonia2

Eosinophil2

Pollution1