• First-rib fractures are considered indicators for increased morbidity and mortality in major trauma. (medscape.com)
  • Eating disorders (EDs) and disordered-eating behaviors (DEBs), pose a high risk of morbidity and mortality, threatening physical health, emotional health, and overall quality of life. (humankinetics.com)
  • Dr. Staudenmayer was promoted to Associate Professor of Surgery in 2016, and continues her research, policy and advocacy work to improve the care and outcomes for patients with traumatic injuries and critical surgical illnesses. (stanford.edu)
  • It is also sued to treat coloboma or people whose iris have been damaged by traumatic injuries. (avocure.com)
  • BACKGROUND: Individual extracerebral organ dysfunction is common after severe traumatic brain injury (TBI) and impacts outcomes. (bvsalud.org)
  • Assessing outcomes objectively is challenging, but the evolution of injury severity scoring systems with sufficient precision and reproducibility now permits trauma centers to compare their processes and outcomes, facilitating identification of best practices that form the foundations of quality improvement programs. (medscape.com)
  • This study was performed to determine the incidence, injury patterns, and outcomes of blunt iliac artery injuries (BIAIs) in association with moderate or severe pelvic fractures. (uthscsa.edu)
  • As whole-body computed tomography (CT) scanning in severely injured trauma patients has been shown to yield beneficial outcomes and is commonly performed in current trauma practice, specific CT findings may be helpful in determining the need for MT. The inferior vena cava (IVC) diameter on the initial CT image has been reported to be a potential predictor of mortality or the necessity for MT [ 2 , 13 - 15 ]. (ceemjournal.org)
  • For all eligible patients, blood sample was drawn for measurement of serum level of vitamin D3 and the correlation of this vitamin with outcomes such as mortality, renal failure, liver failure and etc. was assessed. (ac.ir)
  • Simple rib fractures are the most common injury sustained following blunt chest trauma , accounting for more than half of thoracic injuries from nonpenetrating trauma. (medscape.com)
  • An accurate method for quantitatively summarizing injury severity has many potential applications. (medscape.com)
  • Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. (nih.gov)
  • The extent to which the findings of increased mortality in observational studies may be attributed to the antipsychotic drug as opposed to some characteristic(s) of the patients is not clear. (nih.gov)
  • Journal of Trauma - Injury, Infection and Critical Care , 67 (4), 715-718. (uthscsa.edu)
  • Using a large hospital administrative database, CDC assessed in-hospital mortality risk overall and by demographic and clinical characteristics during the Delta (July-October 2021), early Omicron (January-March 2022), and later Omicron (April-June 2022) variant periods() among patients hospitalized primarily for COVID-19. (cdc.gov)
  • Acute brain injury (ABI) can lead to systemic complications including GI dysfunction. (bvsalud.org)
  • A cohort study by Hemmila et al that included 2,373,130 trauma patients reported statistically significant hospital improvements in major complications and venous thromboembolism, as well as improvements in mortality or hospice after participation in regional collaborative trauma quality improvement programs. (medscape.com)
  • BIAI was also associated with higher mortality, lower extremity amputation, compartment syndrome, and overall complications. (uthscsa.edu)
  • Conclusion: BIAI is a rare diagnosis, but when present it is associated with a higher rate of overall complications and mortality. (uthscsa.edu)
  • [ 1 ] These fractures are rarely life-threatening in themselves but can be an external marker of more severe visceral injury inside the abdomen and the chest. (medscape.com)
  • Motor vehicle accidents were associated with 51.6% of injuries, and blunt chest injury accounted for 95% of rib fractures. (medscape.com)
  • 7 days) was associated with an increased Injury Severity Score (median score, 24), greater number of rib fractures (median, 6), higher rate of lung contusion, and flail chest (35.3% of patients). (medscape.com)
  • The most common mechanism of injury for rib fractures in elderly persons is a fall from height or from standing. (medscape.com)
  • [ 11 ] Because first and second rib fractures are often associated with vascular injury, ED physicians should consider angiography for such patients, especially if symptoms and signs of neurovascular compromise are present. (medscape.com)
  • Background: Although infrequent, injury to the common or external iliac artery in association with pelvic fractures can be devastating, and descriptive data are lacking. (uthscsa.edu)
  • Methods: Patients with moderate or severe pelvic fractures (abbreviated injury score of 3 or 4) were identified from the National Trauma Databank. (uthscsa.edu)
  • 90), Glasgow Coma Score ≤8, Injury Severity Score (ISS) ≥25, femur or lumbosacral fractures, solid organ injury, vascular injury, and hollow viscus injury. (uthscsa.edu)
  • The association of BIAI with moderate or severe pelvic fractures was studied. (uthscsa.edu)
  • Results: Of 6,377 patients with moderate or severe pelvic fractures, 221 (3.5%) had an associated BIAI. (uthscsa.edu)
  • Patients with BIAI were more likely to have ED hypotension, Glasgow Coma Score ≤8, ISS ≥25, genitourinary injury, bowel injury, and severe (abbreviated injury score 4) pelvic fractures. (uthscsa.edu)
  • Vigilance is warranted in the diagnosis and management of this infrequent injury, especially in the setting of severe pelvic fractures. (uthscsa.edu)
  • Pelvic fractures are severe injuries with frequently associated multi-system trauma and a high mortality rate. (biomedcentral.com)
  • Our aim was to assess the association of the pelvic fracture pattern according to the Tile classification system with transfusion requirements and mortality rates, and to evaluate the correlation between the use of pelvic binders and arterial angio-embolization and the mortality of patients with pelvic fractures. (biomedcentral.com)
  • Tile C pelvic fractures are associated with higher transfusion requirements and a higher mortality rate than Tile A or B fractures. (biomedcentral.com)
  • Pelvic fractures are caused by high-energy forces and usually imply the presence of multiple injuries. (biomedcentral.com)
  • While ISS was overwhelmingly predictive of mortality, 12 articles reported limited feasibility of ISS and/or AIS. (bmj.com)
  • Resuscitation, timely identification and adequate treatment of pelvic hemorrhage and significant associated injuries are essential [ 5 ]. (biomedcentral.com)
  • Deaths were analyzed based on injury mechanism (penetrating, blunt trauma and low energy blunt trauma) and cause of death (traumatic brain injury (TBI), hemorrhage, organ dysfunction and other/unknown). (biomedcentral.com)
  • hemorrhage 16.3%, organ dysfunction 15.0%, and other/unknown for 10.1% of the deaths. (biomedcentral.com)
  • Recent changes in trauma care include an emphasis on pain treatment to decrease the potent inflammatory response that results in hyper-coagulability, organ dysfunction, systemic inflammatory response, lung injury, brain injury, depression, and post-traumatic stress disorder [ 1 ]. (biomedcentral.com)
  • Similarly, this technique can be used retrospectively to identify and control for differences in baseline injury severity between patient populations. (medscape.com)
  • Model-estimated adjusted mortality risk differences (aMRDs) (measures of absolute risk) and adjusted mortality risk ratios (aMRRs) (measures of relative risk) for in-hospital death were calculated comparing the early and later Omicron periods with the Delta period. (cdc.gov)
  • Arterial angio-embolization for pelvic bleeding ( p = 0.05) and prehospital pelvic binder placement ( p = 0.5) were not associated with differences in mortality rates. (biomedcentral.com)
  • Perhaps the most important role for injury severity scoring is in trauma care research. (medscape.com)
  • Mortality is used as an outcome parameter of trauma care. (biomedcentral.com)
  • 1 Improvements in the organization of trauma care have resulted in significant reductions in mortality in high-income countries (HIC), such as the USA and Canada. (bmj.com)
  • 46 ] Computed tomography (CT scan) is the main modality used to evaluate the severity of injury. (surgicalneurologyint.com)
  • We analyzed the contribution of MOF to crude and adjusted mortality (age and AIS head) by using logistic regression analysis. (bvsalud.org)
  • Crude and adjusted (age and AIS head) mortality was higher in patients who developed MOF (odds ratio 6.28 [95% confidence interval 4.58-8.60] and odds ratio 5.20 [95% confidence interval 3.53-7.45]), respectively. (bvsalud.org)
  • To address hemorrhage from pelvic injuries, the early application of pelvic binders is now recommended and arterial angio-embolization is widely used for controlling arterial bleeding. (biomedcentral.com)
  • Major hemorrhage remains a leading cause of early death after severe trauma [ 1 ]. (ceemjournal.org)
  • Patients younger than 16 years old and those with cardiac arrest on arrival, penetrating mechanism of injury, Injury Severity Score of less than 9, and those who had not undergone contrast-enhanced CT scans of the torso were excluded. (ceemjournal.org)
  • The ability to predict survival after trauma is perhaps the most fundamental use of injury severity scoring, Furthermore, injury severity scoring can provide objective correlations with resource utiliziation such as length of stay and costs of treatment, as well as inform clinical decisions regarding management of injuries of specific severity. (medscape.com)
  • However, trauma mortality prediction in individual patients by any scoring system is limited and is in general no better than good clinical judgment. (medscape.com)
  • Injury severity scoring is indispensable in stratifying patients into comparable groups for prospective clinical trials. (medscape.com)
  • Clinical review of all trauma deaths was essential to interpret mortality. (biomedcentral.com)
  • Objective: To develop French guidelines on the management of patients with severe abdominal trauma. (bvsalud.org)
  • Securing high-quality mortality statistics requires systematic evaluation of all trauma deaths. (biomedcentral.com)
  • Of the 7422 admissions, 343 deaths were identified of which 36 (10.5%) involved causes not related to the injury. (biomedcentral.com)
  • Thirty-day trauma mortality included 10.5% deaths not directly related to the injury and the exclusion of patients dead on arrival significantly affected the unadjusted mortality rate, ISS, median age and time to death. (biomedcentral.com)
  • Background About 5.8 million people die each year as a result of injuries, and nearly 90% of these deaths occur in low and middle-income countries (LMIC). (bmj.com)
  • Independent risk factors for BIAI included severe pelvic fracture, ED hypotension, ISS ≥25, genitourinary injury, and bowel injury. (uthscsa.edu)
  • The value of the pelvic fracture pattern for predicting transfusion requirements and mortality is not entirely clear. (biomedcentral.com)
  • Data on patient demographics, use of pelvic binders and arterial angio-embolization, transfusion requirements and mortality were extracted from the institutional trauma registry and analyzed. (biomedcentral.com)
  • The Injury Severity Score (ISS) is an established medical score to assess trauma severity. (wikipedia.org)
  • The aim of this study was to assess the effect of Vitamins C and E on mortality, intensive care unit (ICU) length of stay, and Glasgow Outcome Scale-Extended (GOS-E) score of traumatic brain injury (TBI) patients. (surgicalneurologyint.com)
  • Abstract To effectively assess the injury risk of the blunt impact of the SIR-X sponge grenade on the human thorax, in this paper, we used a numerical simulation technique to test the non-lethal kinetic energy projectiles that blunt impact on the Hybrid III 50th dummy model. (journaltocs.ac.uk)
  • Mortality Risk Among Patients Hospitalized Primarily for COVID-19 During the Omicron and Delta Variant Pandemic Periods - United States, April 2020-June 2022. (cdc.gov)
  • Abbreviated Injury Scale E-scooter crashes: Are they a risky underestimated new mode of transport? (ac.ir)
  • These elements, in turn, lead to the reduction of fatalities and injuries in road traffic crashes and disabilities induced by traffic accidents in the world, as well as the related effects, be they economic or psychological, with a view to improving health and safety standards for road users and achieving a better life quality. (qscience.com)
  • A major trauma (or polytrauma) is defined as the Injury Severity Score being greater than 15. (wikipedia.org)
  • Multiorgan failure was defined using the Sequential-related Organ Failure Assessment as the alteration of two or more organs with a score of ≥ 3. (bvsalud.org)
  • The AIS is the basis for the Injury Severity Score (ISS), which is the most widely used measure of injury severity in patients with trauma. (medscape.com)
  • Although, decisions for individual patients should never be based solely on a statistically derived injury severity score, scoring systems can nonetheless serve to estimate quantitatively the level of acuity of injured patients that are applied to adjustments in hospital outcome assessments. (medscape.com)
  • The overall age was 71 years, Injury Severity Score (ISS) 29 and time to death 24 hours (all medians). (biomedcentral.com)
  • Therefore, decisions for individual patients should never be based solely on a statistically derived injury severity score. (medscape.com)
  • Our study suggests that using Vitamins C and E could decrease mortality and length of ICU stay and improve the GOS-E score and functions of the patients with severe TBI. (surgicalneurologyint.com)
  • Abstract During the last decades, there has been an increase in the development and use of kinetic energy non-lethal projectiles, mainly because of their ability to neutralise without inflicting serious injuries. (journaltocs.ac.uk)
  • During this time, NIOSH developed a risk-based model to resume fieldwork, balancing the public health benefit of such fieldwork with the risks of severe acute respiratory syndrome coronavirus 2 exposure and transmission. (cdc.gov)
  • These factors predispose the child to unique patterns of injury as well as unique resuscitative requirements. (netce.com)
  • This course will focus on the patterns of childhood trauma and measures to reduce the mortality and morbidity of these devastating injuries. (netce.com)
  • Characterization of injury severity is crucial to the scientific study of trauma, yet the actual measurement of injury severity began only 50 years ago. (medscape.com)
  • The Abbreviated Injury Scale (AIS) is an anatomically based consensus-derived global severity scoring system that classifies each injury in every body region according to its relative severity on a six-point ordinal scale: Minor Moderate Serious Severe Critical Maximal (currently untreatable). (wikipedia.org)
  • Traumatic brain injury (TBI) is an acute injury to the skull caused by external sources that can be classified into mild, moderate, and severe according to the patient's condition. (surgicalneurologyint.com)
  • 42 ] Severe TBI carries a 30% mortality risk, and roughly half of the patients with moderate or severe TBI regain their independence. (surgicalneurologyint.com)
  • Taking N-acetyl cysteine by mouth for at least 6 months seems to decrease flare-ups by about 40% in people with moderate to severe COPD. (medlineplus.gov)
  • Increased Mortality in Elderly Patients with Dementia-Related Psychosis: Clozapine is not approved for this condition. (nih.gov)
  • The AIS Committee of the Association for the Advancement of Automotive Medicine (AAAM) designed and improves upon the scale. (wikipedia.org)
  • Since its introduction, by the Association for the Advancement of Automotive Medicine (AAAM) International Injury Scaling Committee (IISC), the parent organization of the AIS modified the AIS, most recently in 2005 (AIS-2005). (medscape.com)
  • Even though these are intended to temporarily incapacitate individuals, it is often encountered that kinetic impact projectiles can cause penetration, severe injuries, permanent disabilities and even mortality. (journaltocs.ac.uk)
  • Demographic information, injury type and mechanism, ISS (AIS 05), comorbidity (ASA class) were collected and medical records reviewed. (biomedcentral.com)
  • Compared to pentazocine, ketamine was associated with improved blood pressure for patients with serious injuries. (biomedcentral.com)
  • In addition to the humane reasons for providing optimal pain relief, pain relief is required because the systemic response to pain affects nearly all organ systems. (biomedcentral.com)
  • From the time we start treating this respiratory virus, by day three, four and five of treatment the virus goes from the lungs and then it starts attacking the kidneys and causing severe acute kidney failure that we've never seen before. (pennybutler.com)
  • The risk for COVID-19-associated mortality increases with age, disability, and underlying medical conditions (1). (cdc.gov)
  • Invasive monitors (eg, arterial lines, central lines, and Swan-Ganz catheters) may provide additional data about various hemodynamic parameters (eg, preload, afterload, end-organ perfusion and cardiac output) that are useful in high-risk patients susceptible to tissue hypoperfusion. (medscape.com)
  • These geriatric EDs have geriatric-trained physician and nursing staff as well as specialized equipment, such as gurneys with pressure-reducing mattresses that reduce risk of pressure injuries and improved lighting and acoustics to promote vision and hearing. (msdmanuals.com)
  • The logistic regression analysis showed that age, hemodynamic instability, the need of packed red blood cells concentrates in the initial 24 h, the severity of brain injury, and the need for invasive neuromonitoring were significantly associated with MOF development. (bvsalud.org)
  • MOF was associated with age, hemodynamic instability, the need of packed red blood cells concentrates in the initial 24 h, the severity of brain injury, and the need for invasive neuromonitoring. (bvsalud.org)
  • It seems that consumption of vitamin D supplements might be helpful in decreasing the prevalence of infection, sepsis, and mortality caused by it, especially in older age. (ac.ir)
  • Blunt cerebrovascular injuries (BCVIs) after trauma have traditionally been a rare diagnosis, occurring in 1%-2% of all blunt trauma patients. (bmj.com)
  • In addition to her MD degree, She undertook PhD training in nanomedicine for cancer/infectious disease early detection and to identify potential new treatments for severe infectious/cancer patients. (stanford.edu)
  • Headache, learning disability, epilepsy, and infectious or traumatic head injury were the most common diagnoses. (c-metinhibitors.com)
  • The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. (lookformedical.com)
  • Only age (r=-0.261, p=0.037) and mortality (r=-0.426, p=0.025) showed a significant correlation with mean vitamin D. Sepsis patients with older age and those who died had a lower level of vitamin D. Area under the ROC curve of serum vitamin D level regarding 1-month mortality of the sepsis patients was 0.701 (95%CI: 0.439 â€" 0.964). (ac.ir)
  • A significant and indirect correlation was found between the serum level of vitamin D3 and mortality as well as older age. (ac.ir)
  • Aortic injury is closely associated with a widening of greater than 8 cm measured at the widest points of the mediastinum on an upright anteroposterior chest radiograph. (medscape.com)
  • Therefore, all injuries to the chest should be regarded as potentially life threatening. (journaltocs.ac.uk)
  • The Young-Burgess classification is based on the injury mechanism (lateral compression, anteroposterior compression and vertical shear forces). (biomedcentral.com)
  • Post-traumatic amnesia (PTA), i.e. the period of time running from the injury to recovery of anterograde memory, constitutes the most important parameter in the classification of these injuries 1 . (openorthopaedicsjournal.com)
  • This article reviews the conceptual and statistical background necessary to understand injury severity scoring, presents the most common scoring systems, and addresses new ideas and trends in trauma scoring. (medscape.com)
  • Researchers use multiple independent variables (eg, age, injury severity) to predict the dependent variable (or outcome). (medscape.com)
  • The ability to predict outcome from trauma (ie, mortality) is perhaps the most fundamental use of injury severity scoring, a use that arises from the patient's and the family's desires to know the prognosis. (medscape.com)
  • Consensus regarding previously established parameters for return to play and careful titration of physical activity throughout the ED recovery process are suggested as important for preserving health, preventing re-injury, or relapse and facilitating successful return to sport participation. (humankinetics.com)