• known as "good" cholesterol), very low-density lipoprotein cholesterol, triglycerides, lipoprotein(a) (a family of lipoprotein particles varying in density and size), and ratio of total or LDL-C to HDL-C, were there any significant effects of policosanol. (health.am)
  • Lipoprotein lipase (LPL), the rate-limiting enzyme for hydrolysis of plasma lipoprotein triglycerides, is a normal constituent of the arterial wall. (jci.org)
  • The metabolic syndrome was considered present if three or more of its component parameters (obesity, elevated blood pressure, reduced high density lipoprotein (HDL) cholesterol, elevated triglycerides, and abnormal glucose levels) were present in each officer. (cdc.gov)
  • Gemfibrozil is a lipid regulating agent which decreases serum triglycerides and very low density lipoprotein (VLDL) cholesterol, and increases high density lipoprotein (HDL) cholesterol. (nih.gov)
  • While modest decreases in total and low density lipoprotein (LDL) cholesterol may be observed with gemfibrozil therapy, treatment of patients with elevated triglycerides due to Type IV hyperlipoproteinemia often results in a rise in LDL-cholesterol. (nih.gov)
  • In the primary prevention component of the Helsinki Heart Study, in which 4081 male patients between the ages of 40 and 55 were studied in a randomized, double-blind, placebo-controlled fashion, gemfibrozil therapy was associated with significant reductions in total plasma triglycerides and a significant increase in high density lipoprotein cholesterol. (nih.gov)
  • This subgroup of Type IIb gemfibrozil group patients had a lower mean HDL-cholesterol level at baseline than the Type IIa subgroup that had elevations of LDL-cholesterol and normal plasma triglycerides. (nih.gov)
  • Atorvastatin reduces levels of "bad" cholesterol and triglycerides in the blood while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL). (canadapharmacyonline.com)
  • Total cholesterol, triglycerides and low density lipoprotein cholesterol were not associatedwith moderate Á/severe CAA, while high density lipoprotein cholesterol was protective (OR: 0.4, CI: 0.2 Á/0.8). (pdfmedfinder.com)
  • Fenofibrate is a widely available, low-cost generic drug previously approved by the United States Food and Drug Administration and many other regulatory agencies to reduce the number of fatty substances, such as cholesterol and triglycerides, in the blood, while increasing "good" cholesterol (high-density lipoprotein cholesterol known as HDL). (globaloncologyacademy.org)
  • It is defined by the presence of visceral obesity, elevated triglycerides, decreased HDL, elevated blood pressure and blood glucose. (bvsalud.org)
  • Sedentary behaviors reduce lipoprotein lipase activity, muscle glucose, protein transporter activities, impair lipid metabolism, and diminish carbohydrate metabolism. (researchgate.net)
  • In type I diabetic kidney transplant recipients the levels of HDL cholesterol (1.88 (0.63) mmol/L), postprandial lipemia, and lipoprotein lipase activity were intermediate between pancreas-kidney transplant patients and healthy controls. (ox.ac.uk)
  • Proposed mechanisms of action of OM3FAs include inhibition of diacylglycerol acyltransferase, increased plasma lipoprotein lipase activity, decreased hepatic lipogenesis, and increased hepatic β-oxidation. (ku.edu)
  • If you have a family history of this condition, you should have blood tests to check very low density lipoprotein (VLDL) and triglyceride levels. (medlineplus.gov)
  • The distinctly elevated HDL cholesterol in pancreas-kidney transplant patients can be readily explained by the low postprandial triglyceride levels resulting from a high activity of lipoprotein lipase. (ox.ac.uk)
  • Systemic uric acid concentrations are influenced by dietary levels of purine rich foods, body mass index (BMI), and cardiometabolic risk factors, such as high blood pressure, high density lipoprotein (HDL), triglyceride levels and fasting blood glucose. (salimetrics.com)
  • People with this condition also have high levels of very low density lipoprotein (VLDL). (medlineplus.gov)
  • Omega-3 contains HDL (High-density lipoproteins) which are essential for the production of various enzymes for proper breakdown of fat inside the body. (stroudtimes.com)
  • Our study aimed to assess the cholesterol efflux capacity (CEC) of HDL as a negative risk factor for CVD in individuals with obesity and identify the factors associated with improvement in CEC 3 months following bariatric surgery. (biomedcentral.com)
  • Bariatric surgery (metabolic surgery) is the preferred therapeutic intervention for weight loss among individuals with severe obesity. (biomedcentral.com)
  • Participants were excluded if they met any of the following criteria: endocrinal causes of obesity like Cushing's syndrome, very high risk of anesthetic complications like ASA grade IV, or severe psychiatric disorders like schizophrenia. (biomedcentral.com)
  • The study included 56 individuals with obesity, of whom 30 individuals underwent Roux-en-Y gastric bypass surgery (RYGB) and twenty-six underwent sleeve gastrectomy (SG). (biomedcentral.com)
  • We analyzed data from the School District of Philadelphia for 4 school years (2006-2007 through 2009-2010) to assess the prevalence of and trends in obesity and severe obesity among public school children. (cdc.gov)
  • Both obesity and severe obesity were more common among students in grades 6 through 8 than among children in lower grades or among high school students. (cdc.gov)
  • Asian girls had much lower rates of obesity and severe obesity than any other group. (cdc.gov)
  • Although obesity and severe obesity declined during the 4-year period in almost all demographic groups, the decreases were generally smaller in the groups with the highest prevalence, including high school students, Hispanic males, and African American females. (cdc.gov)
  • Although these data suggest that the epidemic of childhood obesity may have begun to recede in Philadelphia, unacceptably high rates of obesity and severe obesity continue to threaten the health and futures of many school children. (cdc.gov)
  • Our primary goals were to assess the prevalence of obesity and severe obesity among children in the School District of Philadelphia and to determine whether the prevalence of obesity and severe obesity changed between 2006-2007 and 2009-2010, the most recent school year for which data were available. (cdc.gov)
  • and new chronic pulmonary disease (eg, chronic obstructive pulmonary disease, bronchitis, pneumonoconiosis, or asthma) in those without prior chronic pulmonary disease (D). Hollow markers indicate no significant difference between participants with and without severe obesity. (jamanetwork.com)
  • According to NCEP ATP III, an individual should be considered as having MS when he or she presents at least three of the following factors: visceral obesity, hypertriglyceridemia, HDL (reduced cholesterol), altered hypertension and fasting glycemia 27 . (bvsalud.org)
  • For the metabolic syndrome in which multiple mild abnormalities in lipids, waist size (abdominal circumference), blood pressure, and blood sugar increase the risk of CHD, the designated HDL cholesterol levels that contribute to the syndrome are sex-specific. (medscape.com)
  • Plasma lipoproteins are macromolecular complexes of lipids and proteins that are classified by density and electrophoretic mobility. (medscape.com)
  • We determined fasting lipids, lipoproteins and lipolytic enzymes, as well as postprandial lipid metabolism after a standardized oral fat load. (ox.ac.uk)
  • Risk factors progressively attenuated with age, the absolute riskattributable to blood lipids is greater among the elderly Extracranial carotid artery atherosclerosis (CAA) is a Further, intervention studies have shown that major cause of cerebral infarction and transient ischemic lowering of low density lipoprotein (LDL) cholesterol attacks, a disease primarily of the elderly. (pdfmedfinder.com)
  • The researchers measured HDL levels in these mice and found that concentrations of HDL were 80 percent lower than in normal mice. (sciencedaily.com)
  • Omega-3-acid ethyl esters capsules are a combination of ethyl esters of omega 3 fatty acids, principally eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), indicated as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe (≥500 mg/dL) hypertriglyceridemia. (nih.gov)
  • Omega-3-acid ethyl esters may increase levels of low-density lipoprotein (LDL). (nih.gov)
  • Omega-3-acid ethyl esters capsules are indicated as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe (greater than or equal to 500 mg/dL) hypertriglyceridemia. (nih.gov)
  • Low levels of high-density lipoprotein cholesterol (HDL), or hypoalphalipoproteinemia (HA), includes a variety of conditions, ranging from mild to severe, in which concentrations of alpha lipoproteins or high-density lipoprotein (HDL) are reduced. (medscape.com)
  • An arbitrary cutoff is the 10th percentile of HDL cholesterol levels. (medscape.com)
  • The common, mild forms of HA have no characteristic physical findings, but patients may have premature coronary heart or peripheral vascular disease, as well as a family history of low HDL cholesterol levels and premature CHD. (medscape.com)
  • This review addresses the pathogenesis and presenting features of, and the diagnostic tests, therapeutic interventions, and follow-up strategies for, low HDL cholesterol levels. (medscape.com)
  • Plasma total cholesterol levels were not different between the two groups, but DPPD feeding increased the levels of triglyceride (73%, P = 0.007) and HDL cholesterol (26%, P = 0.045). (jci.org)
  • PTSD symptoms were measured with the Impact of Event scale (IES), divided into categories of subclinical, mild, moderate and severe symptom levels. (cdc.gov)
  • Understanding more about how HDL is produced could lead to new treatments to raise its levels. (sciencedaily.com)
  • Low levels of HDL are associated with higher risk of heart attacks, even when total cholesterol levels are normal. (sciencedaily.com)
  • If we want to raise HDL levels, it might make sense to focus on drugs that target the liver," he said. (sciencedaily.com)
  • We will look at levels of heart disease in mice that cannot produce HDL in the liver versus mice that cannot produce it in the vessel walls," said Parks. (sciencedaily.com)
  • Experiment results revealed PSO possessed hypolipidemic and anti-hypertensive activity as it lowered DBP and LDL and increased HDL levels. (scielo.br)
  • Pancreas transplantation with systemic venous drainage of the graft causes elevated plasma levels of insulin, known to be a potent regulator of plasma lipoprotein metabolism. (ox.ac.uk)
  • You have high blood levels of LDL (low density lipoprotein or "bad") cholesterol. (clarksnutrition.com)
  • Gemfibrozil increases levels of high density lipoprotein (HDL) subfractions HDL 2 and HDL 3 , as well as apolipoproteins AI and AII. (nih.gov)
  • p = 0.001] despite a decrease in HDL-C levels. (biomedcentral.com)
  • Emerging data show that high density lipoprotein cholesterol levels, an established negative risk factor for cardiovascular disease improves after bariatric surgery [ 9 ]. (biomedcentral.com)
  • At approved doses, all formulations substantially reduce triglyceride and very-low-density lipoprotein levels. (ku.edu)
  • Consuming collagen can help to maximize HDL levels, which means good cholesterol that can reach up to 6% approximately. (bergencountymedicalspa.com)
  • Retrospective 654 hospitalized patients focused on low-density lipoprotein cholesterol levels, also showing results for HCQ with 605 HCQ patients, unadjusted 30 day mortality relative risk RR 0.37, p = 0.008. (c19hcq.org)
  • Non-survivors had lower total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-c) levels during the entire course of the disease with complete resolution among survivors. (c19hcq.org)
  • This study explored the mediating role of five statin-related biochemical factors [i.e., low-density lipoprotein (LDL)-cholesterol, high-density lipoprotein (HDL)-cholesterol, triglyceride, glucose, and high sensitivity C-reactive protein levels]. (drrath.education)
  • Low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol levels are decreased. (medscape.com)
  • Like other members of its class (the "statins"), simvastatin lowers total serum cholesterol and particularly low density lipoprotein (LDL) cholesterol concentrations, thereby reducing the risk of atherosclerosis and its complications - myocardial infarction and stroke. (nih.gov)
  • The study involved subjects with serum non-HDL-cholesterol of over 200 mg/dL and no previous history of coronary heart disease. (nih.gov)
  • For example, in one of their studies, Proudfit et al 3 concentrated on the number of severe stenoses and correlated them to clinical characteristics such as duration of the history of angina pectoris, distribution of pain, and serum cholesterol. (dovepress.com)
  • Decrease occurs in severe inflammation, acute hepatitis, and cirrhosis. (wikipedia.org)
  • The immune responses associated with severe and fatal COVID-19 manifestations include defective antiviral mechanisms such as type I interferon (IFN) responses ( 3 , 4 ), imbalanced T cell responses ( 5 , 6 ), abnormal expansion of potentially dysfunctional B cells ( 7 ), exuberant inflammation driven by altered myeloid responses ( 8 , 9 ), and production of potentially pathogenic antibodies (autoantibodies and/or proinflammatory antibodies) ( 10 - 12 ). (frontiersin.org)
  • Having an adequate amount of Omega-3 in your diet can also help you to alleviate the most severe inflammation. (stroudtimes.com)
  • Nonalcoholic fatty liver disease (NAFLD) is a chronic liver condition that ranges from isolated liver fat accumulation to severe inflammation and necrosis [known as nonalcoholic steatohepatitis (NASH)], in the absence of alcohol abuse and other causes of liver disease, such as viruses, autoimmunity, or drug-induced hepatitis. (medscape.com)
  • [ 5 ] Many mechanisms have been postulated to explain this association ( i.e., more severe insulin resistance, subclinical inflammation, ectopic fat accumulation with potential cardiolipotoxicity, and worse dyslipidemia). (medscape.com)
  • The alpha-1 fraction does not disappear in alpha 1-antitrypsin deficiency, however, because other proteins, including alpha-lipoprotein and orosomucoid, also migrate there. (wikipedia.org)
  • A low HDL cholesterol level is thought to accelerate the development of atherosclerosis because of impaired reverse cholesterol transport and possibly because of the absence of other protective effects of HDL, such as decreased oxidation of other lipoproteins. (medscape.com)
  • Low density lipoprotein is protected from oxidation and the progression of atherosclerosis is slowed in cholesterol-fed rabbits by the antioxidant N,N'-diphenyl-phenylenediamine. (jci.org)
  • Lipoproteins from DPPD-fed rabbits contained DPPD and were much more resistant to oxidation than control lipoproteins. (jci.org)
  • A prospective analysis by Mora et al investigated the link between cholesterol and cardiovascular events in women and found baseline HDL-C level was consistently and inversely associated with incident coronary and CVD events across a range of LDL-C values. (medscape.com)
  • Though bariatric surgery has been shown to ameliorate proatherogenic dyslipidemia, the present study aimed to examine the effect of bariatric surgery on the cholesterol efflux capacity of HDL in a cohort from the Indian population. (biomedcentral.com)
  • Acute-onset, severe hypertension that is accurately measured using standard techniques and is persistent for 15 minutes or longer is considered a hypertensive emergency. (medscape.com)
  • Intravenous (IV) labetalol and hydralazine have long been considered first-line medications for the management of acute-onset, severe hypertension in pregnant women and women in the postpartum period. (medscape.com)
  • Une recherche documentaire a été effectuée dans PubMed de 1980 à 2021 en utilisant diverses combinaisons de termes MeSH comme tabac, diabète, hypertension, dyslipidémie, trouble dépressif majeur, trouble bipolaire, schizophrénie. (bvsalud.org)
  • The ABCA1 protein is found in many parts of the body, so scientists have been unsure which specific tissues are involved in HDL production. (sciencedaily.com)
  • So, for cholesterol to travel through, it is coated with a layer of protein to make it a lipoprotein. (ecopolitan.com)
  • Atherosclerosis 165 (2002) 317 Á/325 Apolipoproteins A-I and B (apo A-I and B) are the major protein constituents of the high density lipopro-tein (HDL) and LDL fractions, respectively. (pdfmedfinder.com)
  • We report a case of full resolution of severe COVID-19 due to convalescent plasma transfusion. (frontiersin.org)
  • Longitudinal unbiased proteomic analysis of plasma and single-cell transcriptomics of peripheral blood cells conducted prior to and at multiple times after convalescent plasma transfusion identified the key biological processes associated with the transition from severe disease to disease-free state. (frontiersin.org)
  • Moderate reductions in total plasma cholesterol and low density lipoprotein cholesterol were observed for the gemfibrozil treatment group as a whole, but the lipid response was heterogeneous, especially among different Fredrickson types. (nih.gov)
  • Genest J, Mora S, Libby P. Lipoprotein disorders and cardiovascular disease. (medlineplus.gov)
  • Even staining in this zone is due to alpha-1 lipoprotein (high density lipoprotein - HDL). (wikipedia.org)
  • In studies of mice, we provided the first definitive proof that the liver is the source of about 80 percent of the high-density lipoprotein (HDL), or 'good' cholesterol, that circulates in the blood," said John S. Parks, Ph.D., senior researcher, from the school of medicine, which is part of Wake Forest University Baptist Medical Center. (sciencedaily.com)
  • The study explores the hypothesis by investigating effects of consumption of 1000 mg of PSO on total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL), systolic (SBP) and diastolic (DBP) blood pressure ((BP). (scielo.br)
  • However, this is not accompanied by increased non-high-density lipoprotein cholesterol, which is thought to provide a better indication of cardiovascular risk in this patient population. (ku.edu)
  • HDL, or high-density lipoprotein, plays an important role in the risk of heart disease. (bergencountymedicalspa.com)
  • High-density lipoprotein (HDL) cholesterol - HDL carries LDL away from the arteries and promotes free blood flow. (arcpointlabs.com)
  • Increase High Density Lipoprotein (Hdl} Naturally. (cholesterol-guide-review-solution.com)
  • The US National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) redefined the HDL cholesterol level that constitutes a formal coronary heart disease (CHD) risk factor. (medscape.com)
  • For men, a high-risk HDL cholesterol level is still less than 40 mg/dL, but for women, the high-risk HDL cholesterol level is less than 50 mg/dL. (medscape.com)
  • Both LPL & apoC-II deficiency usually present in childhood with recurrent episodes of severe abdominal pain due to acute pancreatitis. (medquizzes.net)
  • Two years into the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide research effort has defined the immunopathology of COVID-19 ( 1 , 2 ). (frontiersin.org)
  • We assessed preadmission achievement of the European Society of Cardiology targets for low-density lipoprotein-cholesterol (LDL- C ) control in patients admitted for acute coronary syndrome. (revespcardiol.org)
  • Results indicated a significantly increased prevalence of the metabolic syndrome among those officers in the severe PTSD symptom category compared with the lowest PTSD severity category (prevalence ratio (PR) = 3.31, 95% C.1. (cdc.gov)
  • Adjustment for several demographic and lifestyle factors (age, education, smoking, alcohol intake) reduced the magnitude of the prevalence ratio slightly for the severe versus subclinical PTSD category (PR = 2.69, 95% C/. = 0.79 - 9.13), with adjustment for age and education accounting for most of the attenuation (PR = 2.71, 95% C/. = 0.99-7.37). (cdc.gov)
  • You can see that you can have a very high HDL and a modestly elevated Cholesterol, and still have a good ratio. (ecopolitan.com)
  • An apo B/apo A-I ratio E/1 wasassociated with moderate Á/severe CAA (OR: 2.4, CI: 1.3 Á/4.4), and the association varied by race (Hispanics OR: 4.3, CI: 1.8 Á/10;non-Hispanics, OR: 1.4, CI: 0.6 Á/3.2). (pdfmedfinder.com)
  • Therefore, receiving collagen supplements can certainly assist even more in lowering the risk of developing any moderate to severe heart conditions. (bergencountymedicalspa.com)
  • apo A-I B/1.2 g/l (OR: 2.0, CI:1.0 Á/3.3) and apo B E/1.4 g/l (OR: 2.0, CI: 1.1 Á/3.6) were associated with moderate Á/severe CAA. (pdfmedfinder.com)
  • Thus, in an elderlypopulation, apo A-I and B were determinants of moderate Á/severe CAA, and the degree of association varied by race/ethnicity# 2002 Elsevier Science Ireland Ltd. All rights reserved. (pdfmedfinder.com)
  • Individuals with inflammatory diseases, cardiomyopathy, renal diseases (detected by hematuria tests) or other severe diseases were excluded from this study. (biomedcentral.com)
  • The biochemical parameters, inflammatory status and CEC of HDL was measured for the obese individuals before bariatric surgery and at 3 months after surgery. (biomedcentral.com)
  • Lipoprotein lipase increases low density lipoprotein retention by subendothelial cell matrix. (jci.org)
  • The very favorable lipid profile in post-diabetic pancreas-kidney transplant recipients could be expected to counteract the severe atherosclerotic risk of long-standing diabetes. (ox.ac.uk)
  • Epidemiological studies have shown that both low HDL-cholesterol and high LDL-cholesterol are independent risk factors for coronary heart disease. (nih.gov)
  • Severe hypertriglyceridemia (≥ 500 mg/dL) is also a risk factor for pancreatitis. (ku.edu)
  • To test their hypothesis and learn more about how HDL is produced, the researchers developed mice without the ABCA1 gene in the liver -- which means their livers cannot produce HDL. (sciencedaily.com)
  • These results profoundly alter our concept of how HDL is manufactured in the body and establish the liver as the single most important source of HDL in a mouse model," said Parks, a professor of pathology. (sciencedaily.com)
  • They are also starting a project to compare the effects of the HDL produced in the liver with the HDL produced in the walls of blood vessels. (sciencedaily.com)
  • Rare but potentially severe adverse events include liver injury, myopathy, rhabdomyolysis, and immune-mediated necrotizing myopathy. (nih.gov)
  • Long-term complications such as muscular and cardiac symptoms as well as liver fibrosis/cirrhosis and hepatocellular carcinoma may have a severe impact on prognosis and quality of life. (nih.gov)
  • Thus, officers with severe PTSD symptoms were approximately three times more likely to have the metabolic syndrome and education may account for some of this association. (cdc.gov)
  • Ichthyotic symptoms may range from mild hyperkeratosis of the palms and soles to severe scaling of lamellar ichthyosis type observed on the trunk. (medscape.com)
  • The oxidative modification of low density lipoprotein (LDL) may play an important role in atherosclerosis. (jci.org)
  • After 10 wk, the DPPD-fed animals had less severe atherosclerosis than did the control animals: thoracic aorta lesion area was decreased by 71% (P = 0.0007), and aortic cholesterol content was decreased by 51% (P = 0.007). (jci.org)
  • In addition, most lipoproteins, have been consistently associated with population-based studies of carotid atherosclerosis have CAA It is notable that for coronary artery so far been performed among Caucasians and in a few disease, although the magnitude of the association is cases African Americans, but there is little informationavailable for Hispanics. (pdfmedfinder.com)
  • Black people are more likely than white people to have severe high blood pressure , as well as heart disease . (webmd.com)
  • Low-density lipoprotein (LDL) cholesterol - Too much LDL cholesterol in your blood can cause blockages in your arteries. (arcpointlabs.com)
  • This impedes blood flow, leading to potentially severe heart disease. (arcpointlabs.com)
  • The etiology of HDL deficiencies ranges from secondary causes, such as smoking, to specific genetic mutations, such as Tangier disease and fish-eye disease. (medscape.com)
  • The Investigators will test the hypothesis that 2-HOBA will reduce modification of HDL and LDL and improve HDL function in humans with heterozygous FH. (nih.gov)
  • An increase appears in severe alcoholics and in women during pregnancy and in puberty. (wikipedia.org)
  • Cases data showed a significant reduction in endpoint LDL and DBP values along with a likewise significant increase in HDL cholesterol. (scielo.br)
  • The mean increase in HDL-cholesterol among the Type IIb patients in this study was 12.6% compared to placebo. (nih.gov)
  • DHA-containing formulations may also increase low-density lipoprotein cholesterol. (ku.edu)
  • While showing initial promise, statins have become highly controversial because of their severe long-time side-effects, including an increase in heart failure, diabetes, and coronary artery calcification. (drrath.education)
  • One or more members of your immediate family (parents or siblings) had premature severe heart disease. (clarksnutrition.com)
  • Much less attention has been placed on characterizing the biological events associated with the clinical resolution of severe COVID-19, even though understanding disease resolution at the molecular and cellular level might contribute new targets of therapeutic interventions against severe COVID-19. (frontiersin.org)
  • One clinical trial from the Netherlands showed wheat germ -derived policosanol ineffective in lowering total cholesterol and low-density lipoprotein cholesterol (LDL-C), sometimes called "bad" cholesterol. (health.am)
  • Plasmapheresis: The main indication for plasmapheresis in patients with RD is a severe or rapidly worsening clinical condition. (medscape.com)
  • Severe heart disease means either a heart attack or sudden death assumed to be heart-related. (clarksnutrition.com)
  • In the review from 1999 through 2006, there were 662 reports of atorvastatin ( Lipitor® ) associated transient global amnesia and severe memory loss. (cholesterol-guide-review-solution.com)
  • Policosanol was tolerated well and no severe adverse events occurred. (health.am)